| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| G Carboni, P Tueting, L Tremolizzo, I Sugaya, J Davis, E Costa, A Guidott. Enhanced dizocilpine efficacy in heterozygous reeler mice relates to GABA turnover downregulation. Neuropharmacology. vol 46. issue 8. 2004-07-13. PMID:15111013. |
in contrast we found that the conversion index of glutamate into gaba (an indirect measurement of gaba turnover rate) is decreased in cortex, hippocampus and striatum of hrm when compared to wtm. |
2004-07-13 |
2023-08-12 |
mouse |
| Wenxia Zhou, Adam W Mailloux, Bruce J Jung, Hayward S Edmunds, Jacqueline F McGint. GABAB receptor stimulation decreases amphetamine-induced behavior and neuropeptide gene expression in the striatum. Brain research. vol 1004. issue 1-2. 2004-06-24. PMID:15033416. |
the purpose of this study was to investigate whether gaba(b) receptor activation blocks acute amphetamine-induced behavioral activity, dopamine release, and neuropeptide mrna expression in the striatum. |
2004-06-24 |
2023-08-12 |
Not clear |
| Michael Gruss, Katharina Brau. Age- and region-specific imbalances of basal amino acids and monoamine metabolism in limbic regions of female Fmr1 knock-out mice. Neurochemistry international. vol 45. issue 1. 2004-06-22. PMID:15082225. |
furthermore, compared to the wildtype animals, the juvenile knock-out mice displayed an increased level of neuronal inhibition in the hippocampus and brainstem reflected by decreased ratios of (aspartate + glutamate)/(taurine + gaba), as well as an increased dopamine (da) turnover in cortical regions, striatum, and hippocampus. |
2004-06-22 |
2023-08-12 |
mouse |
| Stella C Martin, Janine L Steiger, María Clara Gravielle, Helen R Lyons, Shelley J Russek, David H Far. Differential expression of gamma-aminobutyric acid type B receptor subunit mRNAs in the developing nervous system and receptor coupling to adenylyl cyclase in embryonic neurons. The Journal of comparative neurology. vol 473. issue 1. 2004-05-24. PMID:15067715. |
here we examine gaba(b)r expression from rat embryonic day 10 (e10) to e18 compared with adult and ask whether embryonic cortical neurons contain functional gaba(b)r. gaba(b)r1 transcript levels greatly exceed gaba(b)r2 levels in the developing neural tube at e11, and olfactory bulb and striatum at e17 but equalize in most regions of adult nervous tissue, except for the glomerular and granule cell layers of the main olfactory bulb and the striatum. |
2004-05-24 |
2023-08-12 |
rat |
| Stella C Martin, Janine L Steiger, María Clara Gravielle, Helen R Lyons, Shelley J Russek, David H Far. Differential expression of gamma-aminobutyric acid type B receptor subunit mRNAs in the developing nervous system and receptor coupling to adenylyl cyclase in embryonic neurons. The Journal of comparative neurology. vol 473. issue 1. 2004-05-24. PMID:15067715. |
consistent with expression differences, the binding affinity of gaba for gaba(b)rs is significantly lower in adult striatum compared with cerebellum. |
2004-05-24 |
2023-08-12 |
rat |
| G J Hathway, P P A Humphrey, K M Kendric. Somatostatin induces striatal dopamine release and contralateral turning behaviour in the mouse. Neuroscience letters. vol 358. issue 2. 2004-05-19. PMID:15026165. |
application of somatostatin to the striatum of the anaesthetized rat has previously been shown to elicit large increases in extracellular levels of dopamine and gaba via a glutamate-dependent mechanism. |
2004-05-19 |
2023-08-12 |
mouse |
| Henry J Waldvogel, Andy Billinton, Julia H White, Piers C Emson, Richard L M Faul. Comparative cellular distribution of GABAA and GABAB receptors in the human basal ganglia: immunohistochemical colocalization of the alpha 1 subunit of the GABAA receptor, and the GABABR1 and GABABR2 receptor subunits. The Journal of comparative neurology. vol 470. issue 4. 2004-04-28. PMID:14961561. |
that is, gaba acts through gaba(b) receptors, which are located on most of the cell types of the striatum, globus pallidus, and substantia nigra. |
2004-04-28 |
2023-08-12 |
human |
| Emilio Galván, María Sitge. Characterization of the participation of sodium channels on the rise in Na+ induced by 4-aminopyridine (4-AP) in synaptosomes. Neurochemical research. vol 29. issue 2. 2004-04-28. PMID:15002730. |
the participation of voltage-sensitive na+ channels (vssc) on the changes on internal (i) na+, k+, ca2+, and on da, glu, and gaba release caused by different concentrations of 4-ap was investigated in striatum synaptosomes. |
2004-04-28 |
2023-08-12 |
Not clear |
| Benjamin Di Cara, Denise Samuel, Pascal Salin, Lydia Kerkerian-Le Goff, Annie Daszut. Serotonergic regulation of the GABAergic transmission in the rat basal ganglia. Synapse (New York, N.Y.). vol 50. issue 2. 2004-02-24. PMID:12923817. |
here, we examined the consequences of 5,7-dihydroxytryptamine-induced lesion of 5-ht neurons on glutamic acid decarboxylase (gad) activity, mrna expression of the two isoforms of the enzyme, gad65 and gad67, gaba uptake, and extracellular gaba levels in the striatum. |
2004-02-24 |
2023-08-12 |
rat |
| Benjamin Di Cara, Denise Samuel, Pascal Salin, Lydia Kerkerian-Le Goff, Annie Daszut. Serotonergic regulation of the GABAergic transmission in the rat basal ganglia. Synapse (New York, N.Y.). vol 50. issue 2. 2004-02-24. PMID:12923817. |
by contrast, depolarization-induced increases in extracellular levels of gaba were larger in the striatum of 5-ht-deprived rats than in controls, which may be accounted for by an increase in a releasable pool of gaba due to increased synthesis rate. |
2004-02-24 |
2023-08-12 |
rat |
| L F Hernández, G Segovia, F Mor. Effects of activation of NMDA and AMPA glutamate receptors on the extracellular concentrations of dopamine, acetylcholine, and GABA in striatum of the awake rat: a microdialysis study. Neurochemical research. vol 28. issue 12. 2004-02-04. PMID:14649723. |
effects of activation of nmda and ampa glutamate receptors on the extracellular concentrations of dopamine, acetylcholine, and gaba in striatum of the awake rat: a microdialysis study. |
2004-02-04 |
2023-08-12 |
rat |
| L F Hernández, G Segovia, F Mor. Effects of activation of NMDA and AMPA glutamate receptors on the extracellular concentrations of dopamine, acetylcholine, and GABA in striatum of the awake rat: a microdialysis study. Neurochemical research. vol 28. issue 12. 2004-02-04. PMID:14649723. |
the effects of activation of the ampa and nmda ionotropic glutamate receptors on the extracellular concentration of dopamine, acetylcholine, (ach) and gaba in striatum of the awake rat was investigated. |
2004-02-04 |
2023-08-12 |
rat |
| Ryong-Moon Shin, Masao Masuda, Masami Miura, Hiromi Sano, Takuji Shirasawa, Wen-Jie Song, Kazuto Kobayashi, Toshihiko Aosak. Dopamine D4 receptor-induced postsynaptic inhibition of GABAergic currents in mouse globus pallidus neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 23. issue 37. 2004-01-16. PMID:14684868. |
in contrast, dopamine d2 receptor activation hyperpolarizes medium spiny neurons projecting from the striatum to the gp and inhibits gaba release. |
2004-01-16 |
2023-08-12 |
mouse |
| Peter D Alfinito, Sheng-Ping Wang, Lawrence Manzino, Sonia Rijhsinghani, Gail D Zeevalk, Patricia K Sonsall. Adenosinergic protection of dopaminergic and GABAergic neurons against mitochondrial inhibition through receptors located in the substantia nigra and striatum, respectively. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 23. issue 34. 2003-12-16. PMID:14645494. |
when infused into the striatum, cpx (20 ng) potentiated, whereas dmpx (50 ng) prevented malonate-induced gaba loss, but up to 100 ng of cpx or 500 ng of dmpx did not alter malonate-induced striatal dopamine loss. |
2003-12-16 |
2023-08-12 |
mouse |
| I Gourfinkel-An, K Parain, A Hartmann, L Mangiarini, A Brice, G Bates, E C Hirsc. Changes in GAD67 mRNA expression evidenced by in situ hybridization in the brain of R6/2 transgenic mice. Journal of neurochemistry. vol 86. issue 6. 2003-10-17. PMID:12950446. |
a transgenic mouse model of the disease (r6/2) that expresses exon 1 of the human huntington gene with approximately 150 cag repeats has been developed, but gaba concentrations are reported to be normal in the striatum of these animals. |
2003-10-17 |
2023-08-12 |
mouse |
| Ornella Valenti, Michael J Marino, Marion Wittmann, Edward Lis, Anthony G DiLella, Gene G Kinney, P Jeffrey Con. Group III metabotropic glutamate receptor-mediated modulation of the striatopallidal synapse. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 23. issue 18. 2003-09-09. PMID:12904482. |
in rat midbrain slices, electrical stimulation of the striatum evoked gaba(a)-mediated ipscs recorded in all three types of gp neurons. |
2003-09-09 |
2023-08-12 |
mouse |
| Weilie Zhang, Gregory A Ordwa. The alpha2C-adrenoceptor modulates GABA release in mouse striatum. Brain research. Molecular brain research. vol 112. issue 1-2. 2003-07-31. PMID:12670699. |
the alpha2c-adrenoceptor modulates gaba release in mouse striatum. |
2003-07-31 |
2023-08-12 |
mouse |
| Weilie Zhang, Gregory A Ordwa. The alpha2C-adrenoceptor modulates GABA release in mouse striatum. Brain research. Molecular brain research. vol 112. issue 1-2. 2003-07-31. PMID:12670699. |
together, these data imply that alpha(2a)- and alpha(2c)-adrenoceptors are located on different neurons in the striatum, that alpha(2c)-adrenoceptor-mediated effects on striatal gaba release are mediated by an endogenous catecholamine that could be dopamine, and that the alpha(2c)-adrenoceptor effect of rx821002 does not occur at the gabaergic terminal. |
2003-07-31 |
2023-08-12 |
mouse |
| Laurent Nguyen, Brigitte Malgrange, Ingrid Breuskin, Lucien Bettendorff, Gustave Moonen, Shibeshih Belachew, Jean-Michel Rig. Autocrine/paracrine activation of the GABA(A) receptor inhibits the proliferation of neurogenic polysialylated neural cell adhesion molecule-positive (PSA-NCAM+) precursor cells from postnatal striatum. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 23. issue 8. 2003-05-30. PMID:12716935. |
autocrine/paracrine activation of the gaba(a) receptor inhibits the proliferation of neurogenic polysialylated neural cell adhesion molecule-positive (psa-ncam+) precursor cells from postnatal striatum. |
2003-05-30 |
2023-08-12 |
rat |
| Laurent Nguyen, Brigitte Malgrange, Ingrid Breuskin, Lucien Bettendorff, Gustave Moonen, Shibeshih Belachew, Jean-Michel Rig. Autocrine/paracrine activation of the GABA(A) receptor inhibits the proliferation of neurogenic polysialylated neural cell adhesion molecule-positive (PSA-NCAM+) precursor cells from postnatal striatum. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 23. issue 8. 2003-05-30. PMID:12716935. |
we demonstrated that psa-ncam+ neuronal precursors from postnatal striatum expressed gaba(a)r subunits in vitro and in situ. |
2003-05-30 |
2023-08-12 |
rat |