| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Vijay P Sarthy, Robert E Marc, Leonardo Pignataro, Kohichi Tanak. Contribution of a glial glutamate transporter to GABA synthesis in the retina. Neuroreport. vol 15. issue 12. 2004-11-29. PMID:15305132. |
in the present study, we have examined whether a glial glutamate transporter, glast, has a role in gaba synthesis in the mammalian retina. |
2004-11-29 |
2023-08-12 |
mouse |
| Anuradha Dhingra, Eva Faurobert, Nathan Dascal, Peter Sterling, Noga Vard. A retinal-specific regulator of G-protein signaling interacts with Galpha(o) and accelerates an expressed metabotropic glutamate receptor 6 cascade. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 24. issue 25. 2004-11-24. PMID:15215290. |
in retina, galpha(o1) is obligatory in mediating the metabotropic glutamate receptor 6 (mglur6)-initiated on response. |
2004-11-24 |
2023-08-12 |
xenopus_laevis |
| E M Ullian, W B Barkis, S Chen, J S Diamond, B A Barre. Invulnerability of retinal ganglion cells to NMDA excitotoxicity. Molecular and cellular neurosciences. vol 26. issue 4. 2004-11-10. PMID:15276156. |
to determine whether rgcs in an intact retina are vulnerable to excitotoxicity, we retrogradely labeled rgcs in vivo using fluorogold and exposed acutely isolated intact retinas to high concentrations of glutamate or nmda. |
2004-11-10 |
2023-08-12 |
rat |
| N Cuenca, I Pinilla, Y Sauvé, B Lu, S Wang, R D Lun. Regressive and reactive changes in the connectivity patterns of rod and cone pathways of P23H transgenic rat retina. Neuroscience. vol 127. issue 2. 2004-11-09. PMID:15262321. |
by 21 days of age in the p23h rat retina, there is already substantial loss of rods and reduction in rod bipolar dendrites along with reduction of metabotropic glutamate receptor 6 (mglur6) and rod-associated bassoon staining. |
2004-11-09 |
2023-08-12 |
rat |
| Juliette Johnson, David M Sherry, Xiaorong Liu, Robert T Fremeau, Rebecca P Seal, Robert H Edwards, David R Copenhage. Vesicular glutamate transporter 3 expression identifies glutamatergic amacrine cells in the rodent retina. The Journal of comparative neurology. vol 477. issue 4. 2004-10-21. PMID:15329888. |
vesicular glutamate transporter 3 expression identifies glutamatergic amacrine cells in the rodent retina. |
2004-10-21 |
2023-08-12 |
mouse |
| Simone Beretta, Laura Mattavelli, Gessica Sala, Lucio Tremolizzo, Anthony H V Schapira, Andrea Martinuzzi, Valerio Carelli, Carlo Ferrares. Leber hereditary optic neuropathy mtDNA mutations disrupt glutamate transport in cybrid cell lines. Brain : a journal of neurology. vol 127. issue Pt 10. 2004-10-15. PMID:15342361. |
this observation is particularly relevant since eaat1 is the major means of glutamate removal in the inner retina and this prevents retinal ganglion cells being damaged as a result of excitotoxicity. |
2004-10-15 |
2023-08-12 |
Not clear |
| Yee-Kong Ng, Xiao-Xia Zeng, Eng-Ang Lin. Expression of glutamate receptors and calcium-binding proteins in the retina of streptozotocin-induced diabetic rats. Brain research. vol 1018. issue 1. 2004-10-06. PMID:15262206. |
expression of glutamate receptors and calcium-binding proteins in the retina of streptozotocin-induced diabetic rats. |
2004-10-06 |
2023-08-12 |
rat |
| Yee-Kong Ng, Xiao-Xia Zeng, Eng-Ang Lin. Expression of glutamate receptors and calcium-binding proteins in the retina of streptozotocin-induced diabetic rats. Brain research. vol 1018. issue 1. 2004-10-06. PMID:15262206. |
the present results suggest that upregulation of glutamate receptors and calcium-binding proteins may reflect changes of the glutamate and calcium metabolism in the diabetic retina. |
2004-10-06 |
2023-08-12 |
rat |
| Michelle M Ward, Andrew I Jobling, Theresa Puthussery, Lisa E Foster, Erica L Fletche. Localization and expression of the glutamate transporter, excitatory amino acid transporter 4, within astrocytes of the rat retina. Cell and tissue research. vol 315. issue 3. 2004-10-05. PMID:14727177. |
localization and expression of the glutamate transporter, excitatory amino acid transporter 4, within astrocytes of the rat retina. |
2004-10-05 |
2023-08-12 |
rat |
| Michelle M Ward, Andrew I Jobling, Theresa Puthussery, Lisa E Foster, Erica L Fletche. Localization and expression of the glutamate transporter, excitatory amino acid transporter 4, within astrocytes of the rat retina. Cell and tissue research. vol 315. issue 3. 2004-10-05. PMID:14727177. |
mechanisms for the removal of glutamate are vital for maintaining normal function of the retina. |
2004-10-05 |
2023-08-12 |
rat |
| Michelle M Ward, Andrew I Jobling, Theresa Puthussery, Lisa E Foster, Erica L Fletche. Localization and expression of the glutamate transporter, excitatory amino acid transporter 4, within astrocytes of the rat retina. Cell and tissue research. vol 315. issue 3. 2004-10-05. PMID:14727177. |
in this study we examined the expression and localization of the glutamate transporter eaat4 in the rat retina using rt-pcr and immunocytochemistry. |
2004-10-05 |
2023-08-12 |
rat |
| Michelle M Ward, Andrew I Jobling, Theresa Puthussery, Lisa E Foster, Erica L Fletche. Localization and expression of the glutamate transporter, excitatory amino acid transporter 4, within astrocytes of the rat retina. Cell and tissue research. vol 315. issue 3. 2004-10-05. PMID:14727177. |
double labelling of eaat4 and the glutamate transporter eaat1 (glast) revealed extensive colocalization suggesting that astrocytes in the retina express at least two types of glutamate transporters. |
2004-10-05 |
2023-08-12 |
rat |
| Michelle M Ward, Andrew I Jobling, Theresa Puthussery, Lisa E Foster, Erica L Fletche. Localization and expression of the glutamate transporter, excitatory amino acid transporter 4, within astrocytes of the rat retina. Cell and tissue research. vol 315. issue 3. 2004-10-05. PMID:14727177. |
these results suggest that astrocytes within the retina are well placed to provide mechanisms for glutamate removal as well as controlling cellular excitability. |
2004-10-05 |
2023-08-12 |
rat |
| Robert F Mille. D-Serine as a glial modulator of nerve cells. Glia. vol 47. issue 3. 2004-10-04. PMID:15252817. |
however, d-serine proved to be an effective coagonist at the "glycine-binding" site of the n-methyl-d-aspartate (nmda) glutamate receptors, and this observation led to chemical analyses that have now revealed the presence of high levels of d-serine in the central nervous system, including many regions of the brain and retina. |
2004-10-04 |
2023-08-12 |
Not clear |
| Olivier Payet, Christine D'Aldin, Laurence Maurin, Claude Bonne, Agnès Mulle. Anti-excitotoxic activity of trimetazidine in the retina. Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics. vol 20. issue 1. 2004-09-03. PMID:15006162. |
the effect of the drug on the extracellular accumulation of glutamate induced by chemical ischemia was studied by incubating rat retina in vitro. |
2004-09-03 |
2023-08-12 |
rat |
| Olivier Payet, Christine D'Aldin, Laurence Maurin, Claude Bonne, Agnès Mulle. Anti-excitotoxic activity of trimetazidine in the retina. Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics. vol 20. issue 1. 2004-09-03. PMID:15006162. |
these results demonstrate that trimetazidine which is recognized as an efficient drug against ischemic injuries, is also capable of protecting the retina against excitotoxicity by reducing ischemia-induced accumulation of glutamate due in particular to glial transporter inhibition. |
2004-09-03 |
2023-08-12 |
rat |
| Xiong-Li Yan. Characterization of receptors for glutamate and GABA in retinal neurons. Progress in neurobiology. vol 73. issue 2. 2004-08-26. PMID:15201037. |
glutamate and gamma-aminobutyric acid (gaba) are major excitatory and inhibitory neurotransmitters in the vertebrate retina, "a genuine neural center" (ramón y cajal, 1964, recollections of my life, c.e. |
2004-08-26 |
2023-08-12 |
Not clear |
| Xiong-Li Yan. Characterization of receptors for glutamate and GABA in retinal neurons. Progress in neurobiology. vol 73. issue 2. 2004-08-26. PMID:15201037. |
in recent years, glutamate receptors and gaba receptors in the retina have been extensively studied, using multi-disciplinary approaches. |
2004-08-26 |
2023-08-12 |
Not clear |
| Xiong-Li Yan. Characterization of receptors for glutamate and GABA in retinal neurons. Progress in neurobiology. vol 73. issue 2. 2004-08-26. PMID:15201037. |
a variety of glutamate receptor and gaba receptor subtypes found in the retina perform distinct functions, thus providing a wide range of neural integration and versatility of synaptic transmission. |
2004-08-26 |
2023-08-12 |
Not clear |
| A M LeDay, S Ganguly, K H Kulkarni, A Dash, C A Opere, S E Ohi. Effect of hydrogen peroxide on amino acid concentrations in bovine retina and vitreous humor, ex vivo. Methods and findings in experimental and clinical pharmacology. vol 25. issue 9. 2004-08-20. PMID:14685296. |
the aim of the present study was to investigate the effect of h2o2 on glutamate and glycine levels in the bovine retina and vitreous humor, ex vivo. |
2004-08-20 |
2023-08-12 |
cattle |