| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| B Costall, R J Naylo. A comparison of the abilities of typical neuroleptic agents and of thioridazine, clozapine, sulpiride and metoclopramide to antagonise the hyperactivity induced by dopamine applied intracerebrally to areas of the extrapyramidal and mesolimbic systems. European journal of pharmacology. vol 40. issue 1. 1977-01-28. PMID:791660. |
the abilities of the agents tested to antagonise a hyperactivity induced by dopamine in the striatum or in the mesolimbic areas, the nucleus accumbens and tuberculum olfactorium, are compared with the potential of these agents to induce extrapyramidal side effects and to exert an antipsychotic action in man. |
1977-01-28 |
2023-08-11 |
rat |
| C J Pycock, R W Horto. Possible GABA-mediated control of dopamine-dependent behavioural effects from the nucleus accumbens of the rat. Psychopharmacology. vol 49. issue 2. 1977-01-25. PMID:825904. |
similarly on day 1, the direct injection of dopamine into the nucleus accumbens of rats previously injected with eos did not evoke the usual hyperactivity response. |
1977-01-25 |
2023-08-11 |
rat |
| G N Woodruff, P S McCarthy, R J Walke. Studies on the pharmacology of neurones in the nucleus accumbens of the rat. Brain research. vol 115. issue 2. 1977-01-03. PMID:184877. |
in the nucleus accumbens neurones were inhibited by dopamine, adtn, ergometrine, dibutyryl cyclic amp, glycine and gamma-aminobutyric acid. |
1977-01-03 |
2023-08-11 |
rat |
| G N Woodruff, P S McCarthy, R J Walke. Studies on the pharmacology of neurones in the nucleus accumbens of the rat. Brain research. vol 115. issue 2. 1977-01-03. PMID:184877. |
the results are consistent with the suggestion that dopamine is an inhibitory transmitter in the nucleus accumbens and in the caudate nucleus and support the hypothesis that the effects of dopamine are mediated by cyclic amp. |
1977-01-03 |
2023-08-11 |
rat |
| G N Woodruff, P S McCarthy, R J Walke. Studies on the pharmacology of neurones in the nucleus accumbens of the rat. Brain research. vol 115. issue 2. 1977-01-03. PMID:184877. |
the locomotor stimulants adtn and ergometrine mimicked the inhibitory actions of dopamine in both the striatum and in the nucleus accumbens. |
1977-01-03 |
2023-08-11 |
rat |
| G N Woodruff, P S McCarthy, R J Walke. Studies on the pharmacology of neurones in the nucleus accumbens of the rat. Brain research. vol 115. issue 2. 1977-01-03. PMID:184877. |
these results support the suggestion that dopamine receptors in the nucleus accumbens are involved in the actions of locomotor stimulant drugs. |
1977-01-03 |
2023-08-11 |
rat |
| B Costall, R J Naylo. Apomorphine as an antagonist of the dopamine response from the nucleus accumbens. The Journal of pharmacy and pharmacology. vol 28. issue 7. 1976-11-01. PMID:8619. |
apomorphine as an antagonist of the dopamine response from the nucleus accumbens. |
1976-11-01 |
2023-08-11 |
Not clear |
| M F Roizen, I J Kopin, J Zivin, E A Muth, D M Jacobowit. The effect of two anesthetic agents on norepinephrine and dopamine in discrete brain nuclei, fiber tracts, and terminal regions of the rat. Brain research. vol 110. issue 3. 1976-10-01. PMID:947471. |
only in the nucleus accumbens was the dopamine level increased by both anesthetics; cyclopropane, but not halothane anesthesia, also increased the dopamine content of the caudate nucleus, while halothane, but not cyclopropane anesthesia, significantly decreased the dopamine level of the ventral nucleus of the thalamus. |
1976-10-01 |
2023-08-11 |
rat |
| B Costall, R J Naylor, C D Marsden, C J Pycoc. Serotoninergic modulation of the dopamine response from the nucleus accumbens. The Journal of pharmacy and pharmacology. vol 28. issue 6. 1976-09-25. PMID:7657. |
serotoninergic modulation of the dopamine response from the nucleus accumbens. |
1976-09-25 |
2023-08-11 |
Not clear |
| G Bartholin. Differential effect of neuroleptic drugs on dopamine turnover in the extrapyramidal and limbic system. The Journal of pharmacy and pharmacology. vol 28. issue 5. 1976-09-01. PMID:6752. |
in gallamine-immobilized cats, the caudate nucleus and the nucleus accumbens septi were perfused by means of a push-pull cannula and dopamine was measured in the perfusate. |
1976-09-01 |
2023-08-11 |
rat |
| S Wilk, S D Glic. Dopamine metabolism in the nucleus accumbens: the effect of clozapine. European journal of pharmacology. vol 37. issue 1. 1976-09-01. PMID:1278242. |
dopamine metabolism in the nucleus accumbens: the effect of clozapine. |
1976-09-01 |
2023-08-11 |
rat |
| S Wilk, S D Glic. Dopamine metabolism in the nucleus accumbens: the effect of clozapine. European journal of pharmacology. vol 37. issue 1. 1976-09-01. PMID:1278242. |
dopamine metabolism in the nucleus accumbens of the rat was studied by gas chromatographic quantitation of 3,4-dihydroxyphenylacetic acid (dopac) and homovanillic acid (hva). |
1976-09-01 |
2023-08-11 |
rat |
| G N Woodruff, P H Kelly, A O Elkhawa. Effects of dopamine receptor stimulants on locomotor activity of rats with electrolytic or 6-hydroxydopamine-induced lesions of the nucleus accumbens. Psychopharmacologia. vol 47. issue 2. 1976-08-02. PMID:1273217. |
in contrast, rats with selective 6-hydroxydopamine-induced lesions of dopamine terminals in the nucleus accumbens showed a strong stimulation of locomotor activity following injection of this dose or ergometrine. |
1976-08-02 |
2023-08-11 |
rat |
| G N Woodruff, P H Kelly, A O Elkhawa. Effects of dopamine receptor stimulants on locomotor activity of rats with electrolytic or 6-hydroxydopamine-induced lesions of the nucleus accumbens. Psychopharmacologia. vol 47. issue 2. 1976-08-02. PMID:1273217. |
these results support the view that the dopamine receptors in the nucleus accumbens are involved in the actions of locomotor stimulant drugs. |
1976-08-02 |
2023-08-11 |
rat |
| A J Pijnenburg, W M Honig, J A Van der Heyden, J M Van Rossu. Effects of chemical stimulation of the mesolimbic dopamine system upon locomotor activity. European journal of pharmacology. vol 35. issue 1. 1976-06-02. PMID:3421. |
bilateral administration of dopamine, but not of noradrenaline and serotonin, into the nucleus accumbens of non-pretreated rats resulted in stimulation of locomotor activity. |
1976-06-02 |
2023-08-11 |
rat |
| A J Pijnenburg, W M Honig, J A Van der Heyden, J M Van Rossu. Effects of chemical stimulation of the mesolimbic dopamine system upon locomotor activity. European journal of pharmacology. vol 35. issue 1. 1976-06-02. PMID:3421. |
d-amphetamine proved more effective than dopamine in producing locomotor stimulation, whereas both stimulant and depressant effects were observed following injection of apomorphine into the nucleus accumbens. |
1976-06-02 |
2023-08-11 |
rat |
| B Costall, R J Naylo. Antagonism of the hyperactivity induced by dopamine applied intracerebrally to the nucleus accumbens septi by typical neuroleptics and by clozapine, sulpiride and thioridazine. European journal of pharmacology. vol 35. issue 1. 1976-06-02. PMID:1253817. |
antagonism of the hyperactivity induced by dopamine applied intracerebrally to the nucleus accumbens septi by typical neuroleptics and by clozapine, sulpiride and thioridazine. |
1976-06-02 |
2023-08-11 |
Not clear |
| B Costall, R J Naylo. Antagonism of the hyperactivity induced by dopamine applied intracerebrally to the nucleus accumbens septi by typical neuroleptics and by clozapine, sulpiride and thioridazine. European journal of pharmacology. vol 35. issue 1. 1976-06-02. PMID:1253817. |
dopamine administered intracerebrally to the nucleus accumbens septi was shown to induce a dose-dependent hyperactivity following pretreatment with nialamide. |
1976-06-02 |
2023-08-11 |
Not clear |
| B Costall, R J Naylo. Antagonism of the hyperactivity induced by dopamine applied intracerebrally to the nucleus accumbens septi by typical neuroleptics and by clozapine, sulpiride and thioridazine. European journal of pharmacology. vol 35. issue 1. 1976-06-02. PMID:1253817. |
it is suggested that the ability of a drug to antagonise the hyperactivity induced by the injection of dopamine into the nucleus accumbens septi may be of value in the detection of antipsychotic activity. |
1976-06-02 |
2023-08-11 |
Not clear |
| P H Kelly, R J Miller, J L Neumeye. Aporphines. 16. Action of aporphine alkaloids on locomotor activity in rats with 6-hydroxydopamine lesions of the nucleus accumbens. European journal of pharmacology. vol 35. issue 1. 1976-06-02. PMID:1253829. |
in rats with selective bilateral lesions of dopamine terminals in the nucleus accumbens induced by microinjection of 6-hydroxydopamine both compounds produced a marked stimulation of locomotor activity. |
1976-06-02 |
2023-08-11 |
rat |