| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| David Lau, Stephanie Tobin, Horia Pribiag, Shingo Nakajima, Alexandre Fisette, Dominique Matthys, Anna Kristyna Franco Flores, Marie-Line Peyot, S R Murthy Madiraju, Marc Prentki, David Stellwagen, Thierry Alquier, Stephanie Fulto. ABHD6 loss-of-function in mesoaccumbens postsynaptic but not presynaptic neurons prevents diet-induced obesity in male mice. Nature communications. vol 15. issue 1. 2024-12-16. PMID:39681558. |
abhd6 deletion in nucleus accumbens neurons and dopamine ventral tegmental area neurons produces contrasting effects on effortful responding for food. |
2024-12-16 |
2024-12-21 |
mouse |
| Philip J Clark, Volodar M Migovich, Sanjay Das, Wei Xi, Sandhya Kortagere, Rodrigo A Españ. Hypocretin Receptor 1 Blockade Early in Abstinence Prevents Incubation of Cocaine Seeking and Normalizes Dopamine Transmission. bioRxiv : the preprint server for biology. 2024-12-09. PMID:39651183. |
in the present studies, we first examined if incubation of cocaine seeking was associated with aberrant dopamine transmission in the nucleus accumbens after seven days of abstinence from intermittent access to cocaine. |
2024-12-09 |
2024-12-12 |
rat |
| Juan Enriquez-Traba, Miguel Arenivar, Hector E Yarur-Castillo, Chloe Noh, Rodolfo J Flores, Tenley Weil, Snehashis Roy, Ted B Usdin, Christina T LaGamma, Huikun Wang, Valerie S Tsai, Damien Kerspern, Amy E Moritz, David R Sibley, Andrew Lutas, Rosario Moratalla, Zachary Freyberg, Hugo A Tejed. Dissociable control of motivation and reinforcement by distinct ventral striatal dopamine receptors. Nature neuroscience. 2024-12-09. PMID:39653808. |
dopamine (da) release in striatal circuits, including the nucleus accumbens medial shell (mnacsh), tracks separable features of reward like motivation and reinforcement. |
2024-12-09 |
2024-12-12 |
mouse |
| Kelsea R Gildawie, Kerri E Budge, Fair M Vassoler, Elizabeth Yen, Elizabeth M Byrne. Differential Effects of Prenatal Buprenorphine and Methadone on Postnatal Growth and Gene Expression in the Nucleus Accumbens. Developmental psychobiology. vol 67. issue 1. 2024-12-08. PMID:39648276. |
rnascope in situ hybridization was then used to measure expression of genes in the nucleus accumbens (nac) previously associated with hyperphagia in nows infants, including proopiomelanocortin (pomc), neuropeptide y2 receptors (npy2r), and dopamine type 2 receptors (drd2). |
2024-12-08 |
2024-12-11 |
human |
| Zhigang Chen, Shaoyi Duan, Jialu Li, Jianming Su, Hongyu Le. T-2 toxin triggers depression-like behaviors via upregulation of dopamine transporter in nucleus accumbens of male mice. Ecotoxicology and environmental safety. vol 289. 2024-12-01. PMID:39616663. |
t-2 toxin triggers depression-like behaviors via upregulation of dopamine transporter in nucleus accumbens of male mice. |
2024-12-01 |
2024-12-06 |
mouse |
| Zhigang Chen, Shaoyi Duan, Jialu Li, Jianming Su, Hongyu Le. T-2 toxin triggers depression-like behaviors via upregulation of dopamine transporter in nucleus accumbens of male mice. Ecotoxicology and environmental safety. vol 289. 2024-12-01. PMID:39616663. |
in addition, the reduced dopamine (da) level and elevated dopamine transporter (dat) level were found in reward center nucleus accumbens (nac) receiving daergic projection from ventral tegmental area (vta) in brain after t-2 toxin administration, while there was no significant alteration in da synthesis-related tyrosine hydroxylase (th) and aromatic l-amino acid decarboxylase (aadc) in vta and da storage-related vesicle monoamine transporter 2 (vmat2) in nac. |
2024-12-01 |
2024-12-06 |
mouse |
| Arlene Martínez-Rivera, Robert N Fetcho, Lizzie Birmingham, Jin Xu, Ruirong Yang, Careen Foord, Diego Scala-Chávez, Narmin Mekawy, Kristen Pleil, Virginia M Pickel, Conor Liston, Carlos M Castorena, Joshua Levitz, Ying-Xian Pan, Lisa A Briand, Anjali M Rajadhyaksha, Francis S Le. Elevating levels of the endocannabinoid 2-arachidonoylglycerol blunts opioid reward but not analgesia. Science advances. vol 10. issue 48. 2024-11-29. PMID:39612328. |
using fiber photometry with fluorescent sensors for calcium and dopamine (da), we find that enhancing 2-ag levels diminishes opioid reward-related nucleus accumbens (nac) activity and da neurotransmission. |
2024-11-29 |
2024-12-02 |
mouse |
| Refugio Cruz-Trujillo, Daniel Díaz-Urbina, José Alfredo Díaz-Gandarilla, Dolores Guadalupe Vidal-López, Rodrigo Erick Escartín-Pérez, Juan Manuel Mancilla-Diaz, Benjamín Florán, Juan Gabriel Tejas-Juáre. Stimulation of Dopamine D4 Receptors in the Nucleus Accumbens Shell Increases Palatable Food Intake in Satiated Male Rats: Modulation by NMDA and AMPA Receptors. Brain sciences. vol 14. issue 11. 2024-11-27. PMID:39595865. |
the nucleus accumbens (nac) plays a central role in this process, modulating reward mechanisms primarily via dopamine through d2-like receptors (d2r, d3r, d4r). |
2024-11-27 |
2024-11-29 |
rat |
| Pariya Shahani, Hedie Abolghasemi, Shima Abtin, Roghaye Mozafari, Nooshin Barikrow, Batool Ghorbani Yekta, Abbas Haghparas. The interaction effects between opioidergic and D1-like dopamine receptors in the nucleus accumbens on pain-related behaviors in the animal model of acute pain. Pharmacology, biochemistry, and behavior. 2024-11-25. PMID:39586363. |
the interaction effects between opioidergic and d1-like dopamine receptors in the nucleus accumbens on pain-related behaviors in the animal model of acute pain. |
2024-11-25 |
2024-11-28 |
rat |
| Alexa R Zimbelman, Benjamin Wong, Conor H Murray, Marina E Wolf, Michael T Stefani. Dopamine D1 and NMDA Receptor Co-Regulation of Protein Translation in Cultured Nucleus Accumbens Neurons. Neurochemical research. vol 50. issue 1. 2024-11-20. PMID:39567459. |
dopamine d1 and nmda receptor co-regulation of protein translation in cultured nucleus accumbens neurons. |
2024-11-20 |
2024-11-23 |
Not clear |
| Alexa R Zimbelman, Benjamin Wong, Conor H Murray, Marina E Wolf, Michael T Stefani. Dopamine D1 and NMDA Receptor Co-Regulation of Protein Translation in Cultured Nucleus Accumbens Neurons. Neurochemical research. vol 50. issue 1. 2024-11-20. PMID:39567459. |
here we used fluorescent noncanonical amino acid tagging (funcat) to examine whether dopamine modulates protein translation in cultured nucleus accumbens (nac) medium spiny neurons (msn). |
2024-11-20 |
2024-11-23 |
Not clear |
| Rui Wang, Li Zhu, Yunting Fan, Huiqing Du, Wei Han, Fanglin Guan, Yingjie Zhu, Tong Ni, Teng Che. Dopamine D3 receptor mediates natural and methamphetamine rewards via regulating the expression of miR-29c in the nucleus accumbens of mice. Neuropharmacology. 2024-11-03. PMID:39490406. |
dopamine d3 receptor mediates natural and methamphetamine rewards via regulating the expression of mir-29c in the nucleus accumbens of mice. |
2024-11-03 |
2024-11-06 |
mouse |
| Rui Wang, Li Zhu, Yunting Fan, Huiqing Du, Wei Han, Fanglin Guan, Yingjie Zhu, Tong Ni, Teng Che. Dopamine D3 receptor mediates natural and methamphetamine rewards via regulating the expression of miR-29c in the nucleus accumbens of mice. Neuropharmacology. 2024-11-03. PMID:39490406. |
the dopamine d3 receptor (d3r), principally confined to the nucleus accumbens (nac), is involved in regulating natural and drug rewards; however, the molecular mechanisms underlying the associated process remain unclear. |
2024-11-03 |
2024-11-06 |
mouse |
| Abhinav Goyal, Juan Rojas Cabrera, Charles D Blaha, Kendall H Lee, Hojin Shin, Yoonbae O. Ventral tegmental area deep brain stimulation reverses ethanol-induced dopamine increase in the rat nucleus accumbens. Biomedical engineering letters. vol 14. issue 6. 2024-10-28. PMID:39465114. |
recent work has postulated that high frequency deep brain stimulation (dbs) of the ventral tegmental area may reduce dopamine transmission to the nucleus accumbens following acute drug of abuse exposure, thereby mitigating the drug's addictive potential. |
2024-10-28 |
2024-10-30 |
rat |
| Abhinav Goyal, Juan Rojas Cabrera, Charles D Blaha, Kendall H Lee, Hojin Shin, Yoonbae O. Ventral tegmental area deep brain stimulation reverses ethanol-induced dopamine increase in the rat nucleus accumbens. Biomedical engineering letters. vol 14. issue 6. 2024-10-28. PMID:39465114. |
ventral tegmental area deep brain stimulation reverses ethanol-induced dopamine increase in the rat nucleus accumbens. |
2024-10-28 |
2024-10-30 |
rat |
| Abhinav Goyal, Juan Rojas Cabrera, Charles D Blaha, Kendall H Lee, Hojin Shin, Yoonbae O. Ventral tegmental area deep brain stimulation reverses ethanol-induced dopamine increase in the rat nucleus accumbens. Biomedical engineering letters. vol 14. issue 6. 2024-10-28. PMID:39465114. |
the neurophysiology of alcohol use disorder (aud) is complex, but a major contributor to addictive phenotypes is the tendency for drugs of abuse to increase tonic extracellular dopamine (da) levels in the nucleus accumbens (nac). |
2024-10-28 |
2024-10-30 |
rat |
| Huma Ikram, Iqra Atique, Umaira M Moosa, Darakhshan Jabeen Halee. Mitigation of addictive effects induced by lorazepam through concurrent administration of SSRI: Interplay of serotonin and dopamine in caudate and nucleus accumbens. Pakistan journal of pharmaceutical sciences. vol 37. issue 5. 2024-10-26. PMID:39460971. |
mitigation of addictive effects induced by lorazepam through concurrent administration of ssri: interplay of serotonin and dopamine in caudate and nucleus accumbens. |
2024-10-26 |
2024-10-29 |
rat |
| Régulo Olivares-García, Laura López-Cruz, Carla Carratalá-Ros, Paula Matas-Navarro, John D Salamone, Mercè Corre. Mild forced exercise in young mice prevents anergia induced by dopamine depletion in late adulthood: relation to CDNF and DARPP-32 phosphorylation patterns in nucleus accumbens. Neuropharmacology. 2024-10-23. PMID:39442910. |
mild forced exercise in young mice prevents anergia induced by dopamine depletion in late adulthood: relation to cdnf and darpp-32 phosphorylation patterns in nucleus accumbens. |
2024-10-23 |
2024-10-26 |
mouse |
| Karin Ademar, Lisa Ulenius, Anna Loftén, Bo Söderpalm, Louise Adermark, Mia Ericso. Separate mechanisms regulating accumbal taurine levels during baseline conditions and following ethanol exposure in the rat. Scientific reports. vol 14. issue 1. 2024-10-15. PMID:39406746. |
ethanol-induced dopamine release in the nucleus accumbens (nac) is associated with reward and reinforcement, and for ethanol to elevate nac dopamine levels, a simultaneous increase in endogenous taurine is required within the same brain region. |
2024-10-15 |
2024-10-18 |
rat |
| Maximilian Tufvesson-Alm, Cajsa Aranäs, Sebastian Blid Sköldheden, Jesper Vestlund, Christian E Edvardsson, Elisabet Jerlha. LEAP2, a ghrelin receptor inverse agonist, and its effect on alcohol-related responses in rodents. Translational psychiatry. vol 14. issue 1. 2024-10-02. PMID:39358354. |
into the third ventricle) prevented the ability of alcohol to cause locomotor stimulation in male mice, suppressed the memory of alcohol reward and attenuated the dopamine release in the nucleus accumbens caused by alcohol. |
2024-10-02 |
2024-10-05 |
mouse |