| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Adrina Kocharian, A David Redish, Patrick E Rothwel. Individual differences in decision-making shape how mesolimbic dopamine regulates choice confidence and change-of-mind. bioRxiv : the preprint server for biology. 2024-09-30. PMID:39345599. |
nucleus accumbens dopamine signaling is an important neural substrate for decision-making. |
2024-09-30 |
2024-10-02 |
mouse |
| Jun Huang, Sylvain Crochet, Carmen Sandi, Carl C H Peterse. Dopamine dynamics in nucleus accumbens across reward-based learning of goal-directed whisker-to-lick sensorimotor transformations in mice. Heliyon. vol 10. issue 18. 2024-09-26. PMID:39323852. |
dopamine dynamics in nucleus accumbens across reward-based learning of goal-directed whisker-to-lick sensorimotor transformations in mice. |
2024-09-26 |
2024-09-28 |
mouse |
| Jun Huang, Sylvain Crochet, Carmen Sandi, Carl C H Peterse. Dopamine dynamics in nucleus accumbens across reward-based learning of goal-directed whisker-to-lick sensorimotor transformations in mice. Heliyon. vol 10. issue 18. 2024-09-26. PMID:39323852. |
in the mammalian brain, dopamine release in nucleus accumbens is thought to contribute importantly to reward signals for learning and promoting synaptic plasticity. |
2024-09-26 |
2024-09-28 |
mouse |
| Jun Huang, Sylvain Crochet, Carmen Sandi, Carl C H Peterse. Dopamine dynamics in nucleus accumbens across reward-based learning of goal-directed whisker-to-lick sensorimotor transformations in mice. Heliyon. vol 10. issue 18. 2024-09-26. PMID:39323852. |
here, through longitudinal fiber photometry of a genetically-encoded fluorescent sensor, we investigated dopamine signals in the nucleus accumbens of thirsty head-restrained mice as they learned to lick a liquid reward spout in response to single deflections of the c2 whisker across varying reward contingencies. |
2024-09-26 |
2024-09-28 |
mouse |
| Jun Huang, Sylvain Crochet, Carmen Sandi, Carl C H Peterse. Dopamine dynamics in nucleus accumbens across reward-based learning of goal-directed whisker-to-lick sensorimotor transformations in mice. Heliyon. vol 10. issue 18. 2024-09-26. PMID:39323852. |
reward delivery triggered by well-timed licking drove fast transient dopamine increases in nucleus accumbens. |
2024-09-26 |
2024-09-28 |
mouse |
| Sara N Bramlett, Stephanie L Foster, David Weinshenker, John R Heple. Endogenous Regulator of G protein Signaling 14 (RGS14) suppresses cocaine-induced emotionally motivated behaviors in female mice. bioRxiv : the preprint server for biology. 2024-09-24. PMID:39314405. |
we report that rgs14 is strongly expressed in discrete regions of the ventral striatum and extended amygdala in wild-type mice, and is co-expressed with d1 and d2 dopamine receptors in neurons of the nucleus accumbens (nac). |
2024-09-24 |
2024-09-26 |
mouse |
| Sophia J Weber, Alex B Kawa, Madelyn M Beutler, Hayley M Kuhn, Alana L Moutier, Jonathan G Westlake, Lara M Koyshman, Cloe D Moreno, Amanda M Wunsch, Marina E Wol. Dopamine transmission at D1 and D2 receptors in the nucleus accumbens contributes to the expression of incubation of cocaine craving. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2024-09-19. PMID:39300272. |
dopamine transmission at d1 and d2 receptors in the nucleus accumbens contributes to the expression of incubation of cocaine craving. |
2024-09-19 |
2024-09-22 |
rat |
| Chih-Ting Wu, Diego Gonzalez Magaña, Jacob Roshgadol, Lin Tian, Karen K Rya. Dietary protein restriction diminishes sucrose reward and reduces sucrose-evoked mesolimbic dopamine signaling in mice. Appetite. 2024-09-11. PMID:39260700. |
we used modern optical sensors for measuring real-time nucleus accumbens (nac) dopamine dynamics during voluntary sucrose consumption, via fiber photometry, in male c57/bl6j mice maintained on low-protein high-carbohydrate (lphc) or control (con) diet for ∼5 weeks. |
2024-09-11 |
2024-09-14 |
mouse |
| Chenfeng Zhang, Diana Kúkeľová, Hannes Sigrist, Bastian Hengerer, Ramona F Kratzer, Philipp Mracek, Azar Omrani, Moritz von Heimendahl, Christopher R Pryc. Orphan receptor-GPR52 inverse agonist efficacy in ameliorating chronic stress-related deficits in reward motivation and phasic accumbal dopamine activity in mice. Translational psychiatry. vol 14. issue 1. 2024-09-06. PMID:39242529. |
one potential therapeutic approach is restoration of reward anticipation during appetitive behavior, deficits in which co-occur with attenuated nucleus accumbens (nac) activity, possibly due to nac inhibition of mesolimbic dopamine (da) signaling. |
2024-09-06 |
2024-09-10 |
mouse |
| Emily G Peck, Katherine M Holleran, Alyson M Curry, Kimberly M Holter, Paige M Estave, Jonathon P Sens, Jason L Locke, Olivia A Ortelli, Brianna E George, Monica H Dawes, Alyssa M West, Nancy J Alexander, Drew D Kiraly, Sean P Farris, Robert W Gould, Brian A McCool, Sara R Jone. Synaptogyrin-3 Prevents Cocaine Addiction and Dopamine Deficits. bioRxiv : the preprint server for biology. 2024-08-30. PMID:39211138. |
overexpression also enhanced nucleus accumbens dopamine signaling and prevented cocaine-induced deficits, suggesting a putative therapeutic role for synaptogyrin-3 in cocaine use disorder. |
2024-08-30 |
2024-09-04 |
rat |
| Jordan E Elum, Eric R Szelenyi, Barbara Juarez, Alexandria D Murry, Grigory Loginov, Catalina A Zamorano, Pan Gao, Ginny Wu, Scott Ng-Evans, Joshua X Yee, Xiangmin Xu, Sam A Golden, Larry S Zweife. Distinct dynamics and intrinsic properties in ventral tegmental area populations mediate reward association and motivation. Cell reports. vol 43. issue 9. 2024-08-29. PMID:39207900. |
we find that the dopamine subpopulation that projects to the nucleus accumbens (nac) core preferentially encodes reward-predictive cues and prediction errors. |
2024-08-29 |
2024-09-04 |
mouse |
| Xiajie Feng, Ziyuan Ye, Kailai Xie, Shuqing Zhu, Xin Wu, Zhonghua Sun, Xiaohua Feng, Yingfen Mo, Jingwen Liang, Gang Shu, Songbo Wang, Canjun Zhu, Qingyan Jiang, Lina Wan. Effects of heat stress on the feeding preference of yellow-feathered broilers and its possible mechanism. Journal of thermal biology. vol 124. 2024-08-24. PMID:39180919. |
in the central nervous system, consistent with the change in feeding preference, decreased dopamine in the nucleus accumbens (nac) and increased mrna levels of mao-b in the ventral tegmental area (vta) and nac were found in yellow-feathered broilers (p < 0.05). |
2024-08-24 |
2024-08-28 |
Not clear |
| Triana Acevedo-Huergo, Jonathan Sánchez-Yépez, María Soledad Mendoza-Trejo, Isela Hernández-Plata, Magda Giordano, Verónica Mireya Rodrígue. Hypoactivity and neurochemical alterations in the basal ganglia of female Sprague-Dawley rats after repeated exposure to atrazine. Frontiers in toxicology. vol 6. 2024-08-20. PMID:39161789. |
the atr administration increased dopamine and dopac content in the nucleus accumbens and the dopamine and dopac and serotonin and 5-hiaa content in the ventral midbrain. |
2024-08-20 |
2024-08-22 |
rat |
| Paolo S D'Aquil. Licking microstructure in response to novel rewards, reward devaluation and dopamine antagonists: possible role of D1 and D2 medium spiny neurons in the nucleus accumbens. Neuroscience and biobehavioral reviews. 2024-08-19. PMID:39159734. |
licking microstructure in response to novel rewards, reward devaluation and dopamine antagonists: possible role of d1 and d2 medium spiny neurons in the nucleus accumbens. |
2024-08-19 |
2024-08-22 |
Not clear |
| Paolo S D'Aquil. Licking microstructure in response to novel rewards, reward devaluation and dopamine antagonists: possible role of D1 and D2 medium spiny neurons in the nucleus accumbens. Neuroscience and biobehavioral reviews. 2024-08-19. PMID:39159734. |
evidence on the effect of dopamine d1 and d2-like antagonists and of manipulations of reward value on licking microstructure is reanalysed considering recent findings on the role of nucleus accumbens (nac) medium spiny neurons (msns) in the control of sugar intake. |
2024-08-19 |
2024-08-22 |
Not clear |
| Juan C Jiménez, Felipe Cortés-Salazar, Rosa I Ruiz-García, David Hernández, Florencio Mirand. The effects of intra-accumbal administration of the nicotinic acetylcholine receptor agonist cytisine on the operant oral self-administration of ethanol were prevented by the GABAB receptor agonist baclofen in rats. Pharmacology, biochemistry, and behavior. 2024-08-19. PMID:39159761. |
although the mesocorticolimbic dopamine (da) system is the main neurochemical substrate that regulates the addictive and reinforcing effects of ethanol (etoh), other neurotransmitter systems, such as the acetylcholine (ach) system, modulate daergic function in the nucleus accumbens (nacc). |
2024-08-19 |
2024-08-22 |
rat |
| Courtney G Kocum, Yonca Cam, Dusti A Shay, Tim A Schweizer, Ella R Konrad, Tabitha K Houska, Carlos A Sardina, Todd R Schachtman, Victoria J Vieira-Potter, Matthew J Wil. Voluntary wheel running access produces opposite effects in male and female rats on both palatable diet consumption and associated ventral striatal opioid- and dopamine-related gene expression. Frontiers in integrative neuroscience. vol 18. 2024-08-12. PMID:39131599. |
following the final 2 weeks of reestablished and sustained run vs. sed conditions in separate groups of both males and females, reward-related opioid and dopamine gene expression within the nucleus accumbens (acb) brain region were analyzed. |
2024-08-12 |
2024-08-14 |
rat |
| Qian Huang, Hiu Ham Lee, Bryan Volpe, Qingchen Zhang, Chang Xue, Brian C Liu, Yahia R Abuhasan, Lingyun Li, Jeremy S Yang, Julie Egholm, Cristina Gutierrez-Vazquez, Allen Li, Alyssa Lee, Sharon Tang, Chun Wa Wong, Tiemin Liu, Yuan Huang, Raddy L Ramos, Randy F Stout, Abdelfattah El Ouaamari, Francisco J Quintana, Bradford B Lowell, C Ronald Kahn, Emmanuel N Pothos, Weikang Ca. Deletion of murine astrocytic vesicular nucleotide transporter increases anxiety and depressive-like behavior and attenuates motivation for reward. Molecular psychiatry. 2024-08-09. PMID:39122778. |
these behavioral alterations are associated with significant decreases in the basal extracellular dopamine levels in the nucleus accumbens. |
2024-08-09 |
2024-08-13 |
mouse |
| Qian Huang, Hiu Ham Lee, Bryan Volpe, Qingchen Zhang, Chang Xue, Brian C Liu, Yahia R Abuhasan, Lingyun Li, Jeremy S Yang, Julie Egholm, Cristina Gutierrez-Vazquez, Allen Li, Alyssa Lee, Sharon Tang, Chun Wa Wong, Tiemin Liu, Yuan Huang, Raddy L Ramos, Randy F Stout, Abdelfattah El Ouaamari, Francisco J Quintana, Bradford B Lowell, C Ronald Kahn, Emmanuel N Pothos, Weikang Ca. Deletion of murine astrocytic vesicular nucleotide transporter increases anxiety and depressive-like behavior and attenuates motivation for reward. Molecular psychiatry. 2024-08-09. PMID:39122778. |
likewise, ex vivo brain slices from these mice show a strong trend toward a reduction in evoked dopamine release in the nucleus accumbens. |
2024-08-09 |
2024-08-13 |
mouse |
| Chenfeng Zhang, Redas Dulinskas, Christian Ineichen, Alexandra Greter, Hannes Sigrist, Yulong Li, Gregorio Alanis-Lobato, Bastian Hengerer, Christopher R Pryc. Chronic stress deficits in reward behaviour co-occur with low nucleus accumbens dopamine activity during reward anticipation specifically. Communications biology. vol 7. issue 1. 2024-08-09. PMID:39123076. |
chronic stress deficits in reward behaviour co-occur with low nucleus accumbens dopamine activity during reward anticipation specifically. |
2024-08-09 |
2024-08-13 |
mouse |