| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Kazuhito Nakao, Vivek Jeevakumar, Sunny Zhihong Jiang, Yuko Fujita, Noelia B Diaz, Carlos A Pretell Annan, Karen L Eskow Jaunarajs, Kenji Hashimoto, Juan E Belforte, Kazu Nakazaw. Schizophrenia-Like Dopamine Release Abnormalities in a Mouse Model of NMDA Receptor Hypofunction. Schizophrenia bulletin. vol 45. issue 1. 2019-06-19. PMID:29394409. |
here, we report enhanced dopaminomimetic-induced locomotor activity in these mutants, along with bidirectional, site-specific changes in in vivo amphetamine-induced dopamine release: nucleus accumbens (nac) dopamine release was enhanced by amphetamine in postnatal ppp1r2-cre/grin1 knockout (ko) mice, whereas dopamine release was dramatically reduced in the medial pfc (mpfc) compared to controls. |
2019-06-19 |
2023-08-13 |
mouse |
| C Jiang, W-J Lin, M Sadahiro, B Labonté, C Menard, M L Pfau, C A Tamminga, G Turecki, E J Nestler, S J Russo, S R Salto. VGF function in depression and antidepressant efficacy. Molecular psychiatry. vol 23. issue 7. 2019-06-17. PMID:29158577. |
here, we show that vgf (non-acronymic), which is robustly regulated by bdnf/trkb signaling, is downregulated in hippocampus (male/female) and upregulated in nucleus accumbens (nac) (male) in depressed human subjects and in mice subjected to chronic social defeat stress (csds). |
2019-06-17 |
2023-08-13 |
mouse |
| Tara A LeGates, Mark D Kvarta, Jessica R Tooley, T Chase Francis, Mary Kay Lobo, Meaghan C Creed, Scott M Thompso. Reward behaviour is regulated by the strength of hippocampus-nucleus accumbens synapses. Nature. vol 564. issue 7735. 2019-06-17. PMID:30478293. |
hippocampal input to the shell of the nucleus accumbens (nac) is important for driving nac activity |
2019-06-17 |
2023-08-13 |
Not clear |
| Tehila Beiser, Ran Numa, Ron Kohen, Rami Yak. Chronic treatment with Tempol during acquisition or withdrawal from CPP abolishes the expression of cocaine reward and diminishes oxidative damage. Scientific reports. vol 7. issue 1. 2019-06-13. PMID:28894248. |
in previous studies, we reported that pretreatment with the antioxidant tempol attenuated the development and expression of cocaine-induced psychomotor sensitization in rats and diminished cocaine-induced oxidative stress (os) in the prefrontal cortex (pfc) and nucleus accumbens (nac), suggesting a potential role for tempol in interfering with cocaine-related psychomotor sensitization. |
2019-06-13 |
2023-08-13 |
rat |
| David A Seminowicz, Bethany Remeniuk, Samuel R Krimmel, Michael T Smith, Frederick S Barrett, Andreas B Wulff, Andrew J Furman, Stephan Geuter, Martin A Lindquist, Michael R Irwin, Patrick H Fina. Pain-related nucleus accumbens function: modulation by reward and sleep disruption. Pain. vol 160. issue 5. 2019-06-12. PMID:30753171. |
the nucleus accumbens (nac) has been implicated in sleep, reward, and pain modulation, but the relationship between these functional roles is unclear. |
2019-06-12 |
2023-08-13 |
human |
| Sarah C Simmons, Katie Wheeler, Michelle S Mazei-Robiso. Determination of circuit-specific morphological adaptations in ventral tegmental area dopamine neurons by chronic morphine. Molecular brain. vol 12. issue 1. 2019-06-10. PMID:30736837. |
therefore, we sought to determine whether chronic morphine induced similar changes in the morphology of vta da neurons that project to the nucleus accumbens (nac) and prefrontal cortex (pfc). |
2019-06-10 |
2023-08-13 |
Not clear |
| Mahsaneh Vatankhah, Abdolrahman Sarihi, Alireza Komaki, Siamak Shahidi, Abbas Haghparas. AMN082-a metabotropic glutamate receptor type 7 allosteric agonist in the NAc facilitates extinction and inhibits the reinstatement of morphine-induced conditioned place preference in male rats. Brain research bulletin. vol 140. 2019-06-04. PMID:29605484. |
nucleus accumbens (nac) plays a primary role in opioid reward. |
2019-06-04 |
2023-08-13 |
rat |
| Jean-François De Backer, Stéphanie Monlezun, Bérangère Detraux, Adeline Gazan, Laura Vanopdenbosch, Julian Cheron, Giuseppe Cannazza, Sébastien Valverde, Lídia Cantacorps, Mérie Nassar, Laurent Venance, Olga Valverde, Philippe Faure, Michele Zoli, Olivier De Backer, David Gall, Serge N Schiffmann, Alban de Kerchove d'Exaerd. Deletion of EMBO reports. vol 19. issue 9. 2019-06-04. PMID:30002119. |
further, expression of maged1 in the prefrontal cortex (pfc) and the amygdala, but not in dopaminergic or striatal and other gabaergic neurons, is necessary for cocaine-mediated behavioural sensitization, and its expression in the pfc is also required for cocaine-induced extracellular dopamine (da) release in the nucleus accumbens (nac). |
2019-06-04 |
2023-08-13 |
mouse |
| Erin W Noye Tuplin, Matthew R Holaha. Exploring time-dependent changes in conditioned place preference for food reward and associated changes in the nucleus accumbens. Behavioural brain research. vol 361. 2019-06-04. PMID:30576721. |
brains underwent immunohistochemical staining for c-fos and fosb as well as golgi staining to assess dendritic spine density in the nucleus accumbens (nac). |
2019-06-04 |
2023-08-13 |
rat |
| María S García-Gutiérrez, Francisco Navarrete, Jorge Laborda, Jorge Manzanare. Deletion of Dlk1 increases the vulnerability to developing anxiety-like behaviors and ethanol consumption in mice. Biochemical pharmacology. vol 158. 2019-06-03. PMID:30268817. |
quantitative real time polymerase chain reaction (qpcr) studies were carried out to evaluate alterations in targets closely related to da neurotransmission in the reward system, tyrosine hydroxylase (th) in the ventral tegmental area (vta), and μ-opioid receptor (oprm1) in the nucleus accumbens (nac). |
2019-06-03 |
2023-08-13 |
mouse |
| Katherine R Tonn Eisinger, Kellie S Gross, Brian P Head, Paul G Mermelstei. Interactions between estrogen receptors and metabotropic glutamate receptors and their impact on drug addiction in females. Hormones and behavior. vol 104. 2019-05-31. PMID:29505763. |
while this association between ers and mglurs exists in many cell types and brain regions, its effects are perhaps most striking in the nucleus accumbens (nac). |
2019-05-31 |
2023-08-13 |
Not clear |
| Kevin Caref, Saleem M Nicol. Endogenous opioids in the nucleus accumbens promote approach to high-fat food in the absence of caloric need. eLife. vol 7. 2019-05-31. PMID:29582754. |
the nucleus accumbens (nac) opioid system has long been viewed as a critical substrate for this behavior, mainly via contributions to the neural control of consumption and palatability. |
2019-05-31 |
2023-08-13 |
rat |
| Habon A Issa, Nicky Staes, Sophia Diggs-Galligan, Cheryl D Stimpson, Annette Gendron-Fitzpatrick, Jared P Taglialatela, Patrick R Hof, William D Hopkins, Chet C Sherwoo. Comparison of bonobo and chimpanzee brain microstructure reveals differences in socio-emotional circuits. Brain structure & function. vol 224. issue 1. 2019-05-28. PMID:30306256. |
in bonobos and chimpanzees, we compared neuropil fractions in the nucleus accumbens (nac; core and shell), amygdala (whole, accessory basal, basal, central and lateral nuclei), anterior cingulate cortex (acc; dorsal and subgenual), anterior insular cortex (aic), and primary motor cortex (m1). |
2019-05-28 |
2023-08-13 |
chimpanzee |
| Manjun Shen, Yi Yang, Ying Wu, Beibei Zhang, Haishan Wu, Lu Wang, Hui Tang, Jindong Che. L-theanine ameliorate depressive-like behavior in a chronic unpredictable mild stress rat model via modulating the monoamine levels in limbic-cortical-striatal-pallidal-thalamic-circuit related brain regions. Phytotherapy research : PTR. vol 33. issue 2. 2019-05-21. PMID:30474152. |
the monoamine neurotransmitters that involve serotonin (5-ht), norepinephrine (ne), and dopamine (da) were measured in the limbic-cortical-striatal-pallidal-thalamic (lcspt)-circuit related brain regions, including the prefrontal cortex (pfc), nucleus accumbens (nac), striatum (st), amygdala, and hippocampus (hip). |
2019-05-21 |
2023-08-13 |
rat |
| Stan B Floresco, David R Montes, Maric M T Tse, Mieke van Holstei. Differential Contributions of Nucleus Accumbens Subregions to Cue-Guided Risk/Reward Decision Making and Implementation of Conditional Rules. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 38. issue 8. 2019-05-20. PMID:29348192. |
the nucleus accumbens (nac) is a key node within corticolimbic circuitry for guiding action selection and cost/benefit decision making in situations involving reward uncertainty. |
2019-05-20 |
2023-08-13 |
rat |
| Shunnan Ge, Xinyi Geng, Xuelian Wang, Nan Li, Lei Chen, Xinjing Zhang, Yongzhi Huang, Yang Li, Yukun Chen, Shouyan Wang, Guodong Ga. Oscillatory local field potentials of the nucleus accumbens and the anterior limb of the internal capsule in heroin addicts. Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology. vol 129. issue 6. 2019-05-20. PMID:29674090. |
the nucleus accumbens (nac) is known to regulate the motivation and underlie addictive behaviors, and the anterior limb of the internal capsule (alic) is involved in several psychiatric disorders. |
2019-05-20 |
2023-08-13 |
Not clear |
| Beijun Wu, Chunxia Li, Huimeng Le. SAPAP4 Deletion Causes Synaptic Dysfunction in the nucleus accumbens. Biochemical and biophysical research communications. vol 505. issue 4. 2019-05-20. PMID:30322620. |
we also found that the spine density of medium spiny neurons (msns) in the nucleus accumbens (nac) shell was reduced in sapap4-/- mice. |
2019-05-20 |
2023-08-13 |
mouse |
| b' Przemys\\xc5\\x82aw Kowia\\xc5\\x84ski, Gra\\xc5\\xbcyna Lietzau, Aleksandra Steliga, Ewelina Czuba, Beata Ludkiewicz, Monika Wa\\xc5\\x9bkow, Jan H Spodnik, Janusz Mory\\xc5\\x9. Nicotine-induced CREB and DeltaFosB activity is modified by caffeine in the brain reward system of the rat. Journal of chemical neuroanatomy. vol 88. 2019-05-14. PMID:29100904.' |
we aimed at determining the effect of caffeine and nicotine, applied separately or simultaneously, on activation of six structures of the brain reward system: nucleus accumbens (nac), ventral tegmental area (vta), amygdala (amg), hippocampus (hip), medial prefrontal cortex (mpfr) and dorsal striatum (cdp) in the adult male wistar rats. |
2019-05-14 |
2023-08-13 |
rat |
| Chen-Jie Shen, Di Zheng, Ke-Xin Li, Jian-Ming Yang, Hao-Qi Pan, Xiao-Dan Yu, Jia-Yu Fu, Yi Zhu, Qi-Xin Sun, Meng-Yu Tang, Ying Zhang, Peng Sun, Yi Xie, Shumin Duan, Hailan Hu, Xiao-Ming L. Cannabinoid CB Nature medicine. vol 25. issue 2. 2019-05-10. PMID:30643290. |
here, in mice, we identified that bla cholecystokinin (cck) glutamatergic neurons mediated negative reinforcement via d2 medium spiny neurons (msns) in the nucleus accumbens (nac) and that chronic social defeat selectively potentiated excitatory transmission of the cck |
2019-05-10 |
2023-08-13 |
mouse |
| Maryam Noorbakhshnia, Nahid Zarrinimeh. The role of nucleus accumbens shell on acquisition and retrieval stages of morphine state dependent learning. Asian journal of psychiatry. vol 39. 2019-05-08. PMID:30639974. |
in the present study, the effect of transient inactivation of the shell subregion of the nucleus accumbens (nac shell) by lidocaine on the acquisition and retrieval stages of passive avoidance learning (pal) and memory and morphine state-dependent learning (sdl) in male wistar rats was investigated. |
2019-05-08 |
2023-08-13 |
rat |