| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Sheraz Khoja, Nhat Huynh, Liana Asatryan, Michael W Jakowec, Daryl L Davie. Reduced expression of purinergic P2X4 receptors increases voluntary ethanol intake in C57BL/6J mice. Alcohol (Fayetteville, N.Y.). vol 68. 2019-09-25. PMID:29477921. |
second, to gain insights into the changes in ethanol intake, we employed a lentivirus-shrna (lv-shrna) methodology to selectively knockdown p2x4r expression in the nucleus accumbens (nac) core in male c57bl/6j mice. |
2019-09-25 |
2023-08-13 |
mouse |
| Alessandro Piva, Elisabetta Gerace, Marzia Di Chio, Lisa Osanni, Laura Padovani, Lucia Caffino, Fabio Fumagalli, Domenico E Pellegrini-Giampietro, Cristiano Chiamuler. The metaplastic effects of NMDA receptors blockade on reactivation of instrumental memories in rats. Neurobiology of learning and memory. vol 154. 2019-09-23. PMID:29397283. |
separate groups were tested for in-vivo extinction of responding (24 h and 7 d after reactivation) or ex-vivo assessment of transcription factor zif268 and ribosomal protein rps6 phosphorylation in nucleus accumbens (nac) and amygdala (amy). |
2019-09-23 |
2023-08-13 |
rat |
| Rafael Renteria, Tavanna R Buske, Richard A Morriset. Long-term subregion-specific encoding of enhanced ethanol intake by D1DR medium spiny neurons of the nucleus accumbens. Addiction biology. vol 23. issue 2. 2019-09-17. PMID:28656742. |
the nucleus accumbens (nac) is a critical component of the mesocorticolimbic system and is involved in mediating the motivational and reinforcing aspects of ethanol consumption. |
2019-09-17 |
2023-08-13 |
mouse |
| Francisco J Pavon, Antonia Serrano, Nimish Sidhpura, Ilham Polis, David Stouffer, Fernando Rodriguez de Fonseca, Benjamin F Cravatt, Rémi Martin-Fardon, Loren H Parson. Fatty acid amide hydrolase (FAAH) inactivation confers enhanced sensitivity to nicotine-induced dopamine release in the mouse nucleus accumbens. Addiction biology. vol 23. issue 2. 2019-09-17. PMID:28660730. |
nicotine exerts its rewarding effects by promoting an increase in dopamine (da) release in the nucleus accumbens (nac), and this process is influenced by the endocannabinoid system. |
2019-09-17 |
2023-08-13 |
mouse |
| Margaret A Broadwater, Sung-Ho Lee, Yang Yu, Hongtu Zhu, Fulton T Crews, Donita L Robinson, Yen-Yu Ian Shi. Adolescent alcohol exposure decreases frontostriatal resting-state functional connectivity in adulthood. Addiction biology. vol 23. issue 2. 2019-09-17. PMID:28691248. |
frontolimbic network regions-of-interest for data analysis included pfc [prelimbic (prl), infralimbic (il), and orbitofrontal cortex (ofc) portions], nucleus accumbens (nac), caudate putamen (cpu), dorsal hippocampus, ventral tegmental area, amygdala, and somatosensory forelimb used as a control region. |
2019-09-17 |
2023-08-13 |
rat |
| Miriam Gutiérrez-Martos, Benoit Girard, Sueli Mendonça-Netto, Julie Perroy, Emmanuel Valjent, Rafael Maldonado, Miquel Marti. Cafeteria diet induces neuroplastic modifications in the nucleus accumbens mediated by microglia activation. Addiction biology. vol 23. issue 2. 2019-09-17. PMID:28872733. |
the nucleus accumbens (nac) is a key brain area modulating the reinforcing effects of palatable foods and is crucially involved in the development of eating disorders. |
2019-09-17 |
2023-08-13 |
mouse |
| Ali Mohebi, Jeffrey R Pettibone, Arif A Hamid, Jenny-Marie T Wong, Leah T Vinson, Tommaso Patriarchi, Lin Tian, Robert T Kennedy, Joshua D Berk. Dissociable dopamine dynamics for learning and motivation. Nature. vol 570. issue 7759. 2019-09-17. PMID:31118513. |
the dopamine projection from ventral tegmental area (vta) to nucleus accumbens (nac) is critical for motivation to work for rewards and reward-driven learning. |
2019-09-17 |
2023-08-13 |
Not clear |
| Stephen E Chang, Travis P Todd, Kyle S Smit. Paradoxical accentuation of motivation following accumbens-pallidum disconnection. Neurobiology of learning and memory. vol 149. 2019-09-16. PMID:29408054. |
the nucleus accumbens (nac) and ventral pallidum (vp) are reciprocally connected, and activity within this circuit is thought to promote reward learning. |
2019-09-16 |
2023-08-13 |
Not clear |
| Yawei Si, Zhenhua Song, Xiaoyan Sun, Jin-Hui Wan. microRNA and mRNA profiles in nucleus accumbens underlying depression versus resilience in response to chronic stress. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. vol 177. issue 6. 2019-09-16. PMID:30105773. |
high-throughput sequencing was used to analyze mrna and mirna quantity in the nucleus accumbens (nac) harvested from the mice in the groups of control, cums-induced depression (cums-mdd), and cums-resistance to identify molecular profiles of cums-mdd versus cums-resilience. |
2019-09-16 |
2023-08-13 |
mouse |
| Chao Dong, Ji-Chun Zhang, Qian Ren, Min Ma, Youge Qu, Kai Zhang, Wei Yao, Tamaki Ishima, Hisashi Mori, Kenji Hashimot. Deletion of serine racemase confers D-serine -dependent resilience to chronic social defeat stress. Neurochemistry international. vol 116. 2019-09-10. PMID:29550603. |
in wt mice, csds decreased brain-derived neurotrophic factor (bdnf) expression and phosphorylation/activation of its receptor trkb in prefrontal cortex (pfc), dentate gyrus (dg), and the ca3 region of the hippocampus, but increased bdnf and phosphorylated trkb in the nucleus accumbens (nac). |
2019-09-10 |
2023-08-13 |
mouse |
| Mohaddeseh Ebrahimi-Ghiri, Mohammad Nasehi, Mohammad-Reza Zarrindas. The modulatory role of accumbens and hippocampus D2 receptors in anxiety and memory. Naunyn-Schmiedeberg's archives of pharmacology. vol 391. issue 10. 2019-09-10. PMID:30003299. |
the present study investigated the role of dopamine d2 receptors (d2rs) of the dorsal hippocampus (dh) and the nucleus accumbens (nac) and the effect of their dopaminergic activities on anxiety-like behavior and aversive learning using a test-retest elevated plus-maze (epm) paradigm in male wistar rats. |
2019-09-10 |
2023-08-13 |
rat |
| Alberto Cordella, Paraskevi Krashia, Annalisa Nobili, Annabella Pignataro, Livia La Barbera, Maria Teresa Viscomi, Alessandro Valzania, Flavio Keller, Martine Ammassari-Teule, Nicola Biagio Mercuri, Nicola Berretta, Marcello D'Ameli. Dopamine loss alters the hippocampus-nucleus accumbens synaptic transmission in the Tg2576 mouse model of Alzheimer's disease. Neurobiology of disease. vol 116. 2019-09-06. PMID:29778899. |
the functional loop involving the ventral tegmental area (vta), dorsal hippocampus and nucleus accumbens (nac) plays a pivotal role in the formation of spatial memory and persistent memory traces. |
2019-09-06 |
2023-08-13 |
mouse |
| Wyju Jin, Min Sun Kim, Eun Young Jang, Jun Yeon Lee, Jin Gyeom Lee, Hong Yu Kim, Seong Shoon Yoon, Bong Hyo Lee, Suchan Chang, Jae Hyo Kim, Kwang H Choi, Ho Koo, Young Seob Gwak, Scott C Steffensen, Yeon-Hee Ryu, Hee Young Kim, Chae Ha Yan. Acupuncture reduces relapse to cocaine-seeking behavior via activation of GABA neurons in the ventral tegmental area. Addiction biology. vol 23. issue 1. 2019-09-05. PMID:28271626. |
our previous studies showed that acupuncture at a specific shenmen (ht7) points reduced dopamine (da) release in the nucleus accumbens (nac) induced by drugs of abuse. |
2019-09-05 |
2023-08-13 |
rat |
| László István Gerecsei, Tamás Balázsa, Diego Echevarría, Ágota Ádám, Gergely Zachar, András Csilla. Selective neuronal death following exposure to methylenedioxypyrovalerone is accompanied by an inhibition of NMDA receptor NR2B subunit expression. Acta neurobiologiae experimentalis. vol 79. issue 1. 2019-09-03. PMID:31038488. |
in a previous study, methylenedioxypyrovalerone (mdpv), a designer drug of the cathinone family, caused selective enhancement of caspase3 immunoreactive (casp3+) apoptotic cells in the nucleus accumbens (nac) of 7‑day‑old mice. |
2019-09-03 |
2023-08-13 |
mouse |
| Zengjian Wang, Jiliang Fang, Jun Liu, Peijing Rong, Kristen Jorgenson, Joel Park, Courtney Lang, Yang Hong, Bing Zhu, Jian Kon. Frequency-dependent functional connectivity of the nucleus accumbens during continuous transcutaneous vagus nerve stimulation in major depressive disorder. Journal of psychiatric research. vol 102. 2019-08-29. PMID:29674268. |
we investigated the functional connectivity (fc) of the nucleus accumbens (nac) at different frequency bands during real and sham tvns and explored their associations with depressive symptom changes after one month of treatment. |
2019-08-29 |
2023-08-13 |
Not clear |
| Manoj P Dandekar, Ashwini Saxena, Giselli Scaini, Joo Hyun Shin, Agata Migut, Vijayasree Vayalanellore Giridharan, Yuzhi Zhou, Tatiana Barichello, Jair C Soares, Joao Quevedo, Albert J Feno. Medial Forebrain Bundle Deep Brain Stimulation Reverses Anhedonic-Like Behavior in a Chronic Model of Depression: Importance of BDNF and Inflammatory Cytokines. Molecular neurobiology. vol 56. issue 6. 2019-08-29. PMID:30317434. |
interestingly, decreased levels of bdnf in the cus animals were augmented in the plasma, csf, and hippocampus following mfb-dbs, but remained unaltered in the nucleus accumbens (nac). |
2019-08-29 |
2023-08-13 |
rat |
| Alina Strasser, Lijing Xin, Rolf Gruetter, Carmen Sand. Nucleus accumbens neurochemistry in human anxiety: A 7 T European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 29. issue 3. 2019-08-26. PMID:30600114. |
the neurochemical underpinnings of anxiety remain elusive, particularly in deep structures, such as the nucleus accumbens (nac) whose involvement in anxiety is being increasingly recognized. |
2019-08-26 |
2023-08-13 |
human |
| Jia Cheng, Gali Umschweif, Jenny Leung, Yotam Sagi, Paul Greengar. HCN2 Channels in Cholinergic Interneurons of Nucleus Accumbens Shell Regulate Depressive Behaviors. Neuron. vol 101. issue 4. 2019-08-26. PMID:30638901. |
cholinergic interneurons (chis) in the nucleus accumbens (nac) have been implicated in drug addiction, reward, and mood disorders. |
2019-08-26 |
2023-08-13 |
mouse |
| De-Quan Wang, Xin-Ling Wang, Chong-Yang Wang, Yuan Wang, Su-Xia Li, Ke-Zhi Li. Effects of chronic cocaine exposure on the circadian rhythmic expression of the clock genes in reward-related brain areas in rats. Behavioural brain research. vol 363. 2019-08-26. PMID:30682435. |
in cocaine-treated rats, rper1 expression in the suprachiasmatic nucleus (scn), prefrontal cortex (pfc) and ventral tegmental area (vta); rper2 expression in the nucleus accumbens (nac) shell and hippocampus; rper3 expression in the nac core; rcry expression in the scn and pfc; rbmal1 expression in the scn and nac core showed robust circadian rhythms that were essentially identical to those in control rats. |
2019-08-26 |
2023-08-13 |
human |
| Johannes W de Jong, Seyedeh Atiyeh Afjei, Iskra Pollak Dorocic, James R Peck, Christine Liu, Christina K Kim, Lin Tian, Karl Deisseroth, Stephan Lamme. A Neural Circuit Mechanism for Encoding Aversive Stimuli in the Mesolimbic Dopamine System. Neuron. vol 101. issue 1. 2019-08-20. PMID:30503173. |
using in vivo fiber photometry, we simultaneously recorded activity in da terminals in different nucleus accumbens (nac) subnuclei during an aversive and reward conditioning task. |
2019-08-20 |
2023-08-13 |
Not clear |