| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ashley E Smith, Kehinde O Ogunseye, Julia N DeBenedictis, Joanna Peris, James M Kasper, Jonathan D Homme. Glutamatergic projections from homeostatic to hedonic brain nuclei regulate intake of highly palatable food. Scientific reports. vol 10. issue 1. 2021-05-03. PMID:33328492. |
hedonic feeding is driven, in part, by the reinforcing properties of highly palatable food (hpf), which is mediated by the nucleus accumbens (nac). |
2021-05-03 |
2023-08-13 |
Not clear |
| Daniel J Christoffel, Jessica J Walsh, Boris D Heifets, Paul Hoerbelt, Sophie Neuner, Gordon Sun, Vinod K Ravikumar, Hemmings Wu, Casey H Halpern, Robert C Malenk. Input-specific modulation of murine nucleus accumbens differentially regulates hedonic feeding. Nature communications. vol 12. issue 1. 2021-05-03. PMID:33837200. |
here, we show that modulation of prefrontal cortex (pfc) and anterior paraventricular thalamus (apvt) excitatory inputs to the nucleus accumbens (nac), a key node of reward circuitry, has opposing effects on high fat intake in mice. |
2021-05-03 |
2023-08-13 |
mouse |
| Kadri Kõiv, Kai Tiitsaar, Karita Laugus, Jaanus Harr. Extracellular Dopamine Levels in Nucleus Accumbens after Chronic Stress in Rats with Persistently High vs. Low 50-kHz Ultrasonic Vocalization Response. Brain sciences. vol 11. issue 4. 2021-05-02. PMID:33917789. |
to examine whether these differential responses are associated with dopaminergic neurotransmission in the nucleus accumbens (nac), juvenile male wistar rats were categorized as of high or low positive affectivity (hc and lc, respectively), and after reaching adulthood, extracellular dopamine (da) levels in the nac shell were measured using in vivo microdialysis after three weeks of cvs. |
2021-05-02 |
2023-08-13 |
rat |
| Daniel J Torres, Jordan T Yorgason, Catherine C Mitchell, Ayaka Hagiwara, Marilou A Andres, Suguru Kurokawa, Scott C Steffensen, Frederick P Bellinge. Selenoprotein P Modulates Methamphetamine Enhancement of Vesicular Dopamine Release in Mouse Nucleus Accumbens Via Dopamine D2 Receptors. Frontiers in neuroscience. vol 15. 2021-05-02. PMID:33927588. |
increased synaptic da release in the nucleus accumbens (nac) is a central component of the physiological effects of drugs of abuse. |
2021-05-02 |
2023-08-13 |
mouse |
| Natalie N Nawarawong, Christopher M Olse. Within-animal comparisons of novelty and cocaine neuronal ensemble overlap in the nucleus accumbens and prefrontal cortex. Behavioural brain research. vol 379. 2021-04-30. PMID:31614186. |
using the tettag mouse model and fos immunohistochemistry, we measured neurons engaged by novelty and acute cocaine exposure, respectively in the prefrontal cortex (pfc) and nucleus accumbens (nac). |
2021-04-30 |
2023-08-13 |
mouse |
| E Alvarez-Salas, F Gama, G Matamoros-Trejo, M I Amaya, P de Gortar. TRH in the nucleus accumbens acts downstream to α-MSH to decrease food intake in rats. Neuroscience letters. vol 739. 2021-04-30. PMID:32980456. |
the nucleus accumbens (nac) is part of the latter, a brain circuit involved in processing reward stimuli and the appetitive motivation of feeding. |
2021-04-30 |
2023-08-13 |
rat |
| Anett Schumacher, Marlen Haegele, Jakob Spyth, Andreas Mose. Electrical high frequency stimulation of the nucleus accumbens shell does not modulate depressive-like behavior in rats. Behavioural brain research. vol 378. 2021-04-29. PMID:31589894. |
while research suggests that the nucleus accumbens (nac) plays an important role in depression, studies using nac dbs to improve depressive behavior have not been able to fully explain underlying molecular mechanisms. |
2021-04-29 |
2023-08-13 |
rat |
| Rebecca S Hofford, Tanner J Euston, Rashaun S Wilson, Katherine R Meckel, Emily G Peck, Arthur Godino, Joseph A Landry, Erin S Calipari, TuKiet T Lam, Drew D Kiral. Granulocyte-Colony Stimulating Factor Reduces Cocaine-Seeking and Downregulates Glutamatergic Synaptic Proteins in Medial Prefrontal Cortex. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 41. issue 7. 2021-04-29. PMID:33361463. |
quantitative assessment of changes in the proteomic landscape in the nucleus accumbens (nac) and medial prefrontal cortex (mpfc) were performed via data-independent acquisition (dia) mass spectrometry analysis. |
2021-04-29 |
2023-08-13 |
rat |
| Eric Eyolfson, Dhyey Bhatt, Melinda Wang, Alexander W Lohman, Richelle Mychasiu. Paternal exposure to exercise and/or caffeine and alcohol modify offspring behavioral and pathophysiological recovery from repetitive mild traumatic brain injury in adolescence. Genes, brain, and behavior. 2021-04-29. PMID:33876557. |
post-mortem quantitative real-time polymerase chain reaction (qrt-pcr) was used to assess gene expression in the prefrontal cortex (pfc), nucleus accumbens (nac) and changes in telomere length. |
2021-04-29 |
2023-08-13 |
Not clear |
| Serguei Liachenko, Jaivijay Ram. Sex differences in the effect of acute administration of nicotine on MRS-measured metabolic profile of the rat brain. Neuroscience research. vol 157. 2021-04-28. PMID:31381938. |
proton mrs was used to monitor changes of specific neurometabolites in hippocampus (hc), nucleus accumbens (nac), and anterior cingulate cortex (acc) of rats of both sexes after single intraperitoneal injection of nicotine. |
2021-04-28 |
2023-08-13 |
rat |
| Denise F Happ, Gregers Wegener, R Andrew Taske. Effect of ischemic lesions in medial prefrontal cortex and nucleus accumbens on affective behavior in rats. Behavioural brain research. vol 378. 2021-04-28. PMID:31521735. |
the aim of this study was to examine the effects of unilateral microinjections of the vasoconstrictor endothelin-1 (et-1) in the mpfc alone or in combination with the nucleus accumbens (nac) on the behavior of rats after 2 and 6 weeks. |
2021-04-28 |
2023-08-13 |
mouse |
| L M Molina-Martínez, J Juáre. Differential expression of μ-opioid receptors in the nucleus accumbens, amygdala and VTA depends on liking for alcohol, chronic alcohol intake and estradiol treatment. Behavioural brain research. vol 378. 2021-04-28. PMID:31550484. |
changes in alcohol consumption and mor expression levels were assessed in the nucleus accumbens (nac), amygdala (amy) and ventral tegmental area (vta) at 5 and 10 weeks after ev treatment. |
2021-04-28 |
2023-08-13 |
rat |
| Thomas Elle, Mesbah Alam, Charlene Voigt, Joachim K Krauss, Nadine John, Kerstin Schwab. Deep brain stimulation of the thalamic centromedian-parafascicular nucleus improves behavioural and neuronal traits in a rat model of Tourette. Behavioural brain research. vol 378. 2021-04-28. PMID:31614188. |
additionally, the neuronal activity of the dorsomedial striatum (dms) and the nucleus accumbens (nac), as well as its coherence with the sensorimotor cortex (sm-ctx) was recorded after apomorphine injection and cm-pf dbs. |
2021-04-28 |
2023-08-13 |
rat |
| Yolanda Campos-Jurado, Lucía Martí-Prats, Jose A Morón, Ana Polache, Luis Granero, Lucía Hipólit. Dose-dependent induction of CPP or CPA by intra-pVTA ethanol: Role of mu opioid receptors and effects on NMDA receptors. Progress in neuro-psychopharmacology & biological psychiatry. vol 100. 2021-04-28. PMID:31978422. |
finally, modifications of the expression of nmda receptor subunits in the nucleus accumbens (nac) and hippocampus after ethanol-induced cpp were analyzed at the proteomic and transcriptomic levels by western blot and in situ hybridation rnascope techniques, respectively. |
2021-04-28 |
2023-08-13 |
Not clear |
| Jesper Vestlund, Elisabet Jerlha. The glucagon-like peptide-1 receptor agonist, exendin-4, reduces sexual interaction behaviors in a brain site-specific manner in sexually naïve male mice. Hormones and behavior. vol 124. 2021-04-28. PMID:32450068. |
this reduction in reward involves activation of glp-1 receptors (glp-1r) within areas processing natural and artificial rewards, including the laterodorsal tegmental area (ldtg), ventral tegmental area (vta) and nucleus accumbens (nac) shell. |
2021-04-28 |
2023-08-13 |
mouse |
| Chiomah Ezeomah, Kathryn A Cunningham, Sonja J Stutz, Robert G Fox, Natalya Bukreyeva, Kelly T Dineley, Slobodan Paessler, Irma E Cisnero. Fentanyl self-administration impacts brain immune responses in male Sprague-Dawley rats. Brain, behavior, and immunity. vol 87. 2021-04-27. PMID:32165150. |
several innate immune markers, as well as opioid receptors (ors) and intracellular pattern recognition receptors (prrs), were interrogated within nodes of the neurocircuitry involved in oud processes, including the prefrontal cortex (pfc), nucleus accumbens (nac), caudate putamen (cpu), hippocampus (hip) and midbrain (mb). |
2021-04-27 |
2023-08-13 |
rat |
| Liang Gong, Siyi Yu, Ronghua Xu, Duan Liu, Xijian Dai, Zhengyan Wang, Youping Hu, Bohua Yan, Yu Kui, Bei Zhang, Fen Fen. The abnormal reward network associated with insomnia severity and depression in chronic insomnia disorder. Brain imaging and behavior. vol 15. issue 2. 2021-04-27. PMID:32710331. |
nucleus accumbens (nac) - based functional connectivity (nafc) was evaluated to explore the differences in the reward network between the cid and hc groups. |
2021-04-27 |
2023-08-13 |
Not clear |
| Golnaz Faramarzi, Elham Charmchi, Sakineh Salehi, Morteza Zendehdel, Abbas Haghparas. Intra-accumbal dopaminergic system modulates the restraint stress-induced antinociceptive behaviours in persistent inflammatory pain. European journal of pain (London, England). vol 25. issue 4. 2021-04-27. PMID:33342008. |
nucleus accumbens (nac), as an important component of the mesolimbic dopaminergic system, has a major role in pain modulation and is differentially affected by stress. |
2021-04-27 |
2023-08-13 |
Not clear |
| Kevin M Manz, Jennifer C Becker, Carrie A Grueter, Brad A Gruete. Histamine H Biological psychiatry. vol 89. issue 6. 2021-04-23. PMID:33012522. |
histidine decarboxylase-containing varicosities diffusely innervate striatal and mesolimbic networks, including the nucleus accumbens (nac). |
2021-04-23 |
2023-08-13 |
Not clear |
| E J Fernández-Pérez, S Gallegos, L Armijo-Weingart, A Araya, N O Riffo-Lepe, F Cayuman, L G Aguay. Changes in neuronal excitability and synaptic transmission in nucleus accumbens in a transgenic Alzheimer's disease mouse model. Scientific reports. vol 10. issue 1. 2021-04-22. PMID:33177601. |
for example, volumetric studies in humans have shown a significant atrophy of the striatum, particularly in the nucleus accumbens (nac). |
2021-04-22 |
2023-08-13 |
mouse |