| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M J Castelhano-Carlos, S Aslani, N Sous. The Impact of Physical Enrichment in the Structure of the Medial Prefrontal Cortex and Nucleus Accumbens of the Adult Male Rat Brain. Neuroscience. vol 454. 2021-05-14. PMID:32058067. |
herein, we assessed neuronal plasticity as a consequence of living in the phw, by comparing the structure of the medial prefrontal cortex (mpfc) and the nucleus accumbens (nac), two brain areas involved in the circuitry regulating motivation and reward. |
2021-05-14 |
2023-08-13 |
rat |
| Kenneth Blum, David Baron, Thomas McLaughlin, Mark S Gol. Molecular neurological correlates of endorphinergic/dopaminergic mechanisms in reward circuitry linked to endorphinergic deficiency syndrome (EDS). Journal of the neurological sciences. vol 411. 2021-05-14. PMID:32088516. |
the consensus of the current literature strongly supports the concept that brain neurotransmitters, and second messengers involved in the net release of dopamine in the mesolimbic region, especially the nucleus accumbens (nac), is directly linked to motivation, anti-stress, incentive salience (wanting), and well-being. |
2021-05-14 |
2023-08-13 |
Not clear |
| Katsumasa Muneoka, Yasunori Oda, Masaaki Iwata, Masaomi Iyo, Kenji Hashimoto, Yukihiko Shirayam. Monoaminergic balances predict non-depression-like phenotype in Learned Helplessness Paradigm. Neuroscience. vol 440. 2021-05-14. PMID:32222554. |
here, we measured the levels of monoamines, including noradrenaline (na), serotonin (5-ht), and dopamine (da), and their metabolites in the medial prefrontal cortex (mpfc), orbitofrontal cortex (ofc), hippocampus, nucleus accumbens (nac), amygdala, and striatum in lh, non-lh, and non-manipulated (naïve) rats. |
2021-05-14 |
2023-08-13 |
rat |
| Joshua D Manduca, Rachel-Karson Thériault, Olivia O F Williams, Duncan J Rasmussen, Melissa L Perreaul. Transient Dose-dependent Effects of Ketamine on Neural Oscillatory Activity in Wistar-Kyoto Rats. Neuroscience. vol 441. 2021-05-14. PMID:32417341. |
animals received a low (10 mg/kg) or high (30 mg/kg) dose of ketamine and temporal changes in neural oscillatory activity recorded from the prefrontal cortex (pfc), cingulate cortex (cg), and nucleus accumbens (nac) for ninety minutes. |
2021-05-14 |
2023-08-13 |
rat |
| Alexandra Roldán, Maria J Portella, Frederic Sampedro, Anna Alonso-Solís, Salvador Sarró, Mireia Rabella, Eva M Grasa, Enric Álvarez, Rodrigo Rodríguez, Valle Camacho, Alejandro Fernandez-León, Francisco Fuentes, Josefina Pérez-Blanco, Víctor Pérez, Peter Mckenna, Edith Pomarol-Clotet, Iluminada Corripi. Brain metabolic changes in patients with treatment resistant schizophrenia treated with deep brain stimulation: A series of cases. Journal of psychiatric research. vol 127. 2021-05-14. PMID:32485433. |
so far there has been only one completed trial in schizophrenia, in which seven treatment resistant patients received dbs in the subgenual anterior cingulate cortex (sgacc, n = 4) or the nucleus accumbens (nac, n = 3); four met symptomatic response criteria over the trial period. |
2021-05-14 |
2023-08-13 |
Not clear |
| Carmen Rodríguez-Rivera, Rocío Girón, Eva Sánchez-Robles, Carmen González-Martín, Carlos Goicoechea, Luis F Alguaci. Sciatic Nerve Ligation Downregulates Mitochondrial Clusterin in the Rat Prefrontal Cortex. Neuroscience. vol 446. 2021-05-14. PMID:32798589. |
we studied the effects of sciatic nerve ligation on mechanical allodynia (von frey test), anxiety (elevated plus maze test), plasma clusterin (enzyme-linked immunosorbent assay) and clusterin expression in the nucleus accumbens (nac) and prefrontal cortex (pfc) of adult male wistar rats (western blot). |
2021-05-14 |
2023-08-13 |
human |
| Mark S Gold, David Baron, Abdalla Bowirrat, Kenneth Blu. Neurological correlates of brain reward circuitry linked to opioid use disorder (OUD): Do homo sapiens acquire or have a reward deficiency syndrome? Journal of the neurological sciences. vol 418. 2021-05-14. PMID:32957037. |
the extant literature confirms that an array of polymorphic genes related to- neurotransmitters and second messengers govern the net release of dopamine in the nucleus accumbens (nac) in the mesolimbic region of the brain. |
2021-05-14 |
2023-08-13 |
Not clear |
| Daniel E Kochli, Sara E Keefer, Utsav Gyawali, Donna J Cal. Basolateral Amygdala to Nucleus Accumbens Communication Differentially Mediates Devaluation Sensitivity of Sign- and Goal-Tracking Rats. Frontiers in behavioral neuroscience. vol 14. 2021-05-14. PMID:33324182. |
rats rely on communication between the basolateral amygdala (bla) and nucleus accumbens (nac) to express lever directed approach in a pavlovian lever autoshaping (pla) task that distinguishes sign- and goal-tracking rats. |
2021-05-14 |
2023-08-13 |
rat |
| Justin K Siemann, Brad A Grueter, Douglas G McMaho. Rhythms, Reward, and Blues: Consequences of Circadian Photoperiod on Affective and Reward Circuit Function. Neuroscience. vol 457. 2021-05-14. PMID:33385488. |
we next highlight how brain regions crucial for the serotoninergic system (i.e., dorsal raphe nucleus; drn), and dopaminergic (i.e., nucleus accumbens; nac and ventral tegmental area; vta) system are intertwined in overlapping circuitry, and play influential roles in the pathology of mood and reward-based disorders. |
2021-05-14 |
2023-08-13 |
human |
| Erin W Noye Tuplin, Faye Chleilat, Erna Alukic, Raylene A Reime. The Effects of Human Milk Oligosaccharide Supplementation During Critical Periods of Development on the Mesolimbic Dopamine System. Neuroscience. vol 459. 2021-05-14. PMID:33588004. |
the brain reward system, specifically the mesolimbic dopamine (da) projections from the ventral tegmental area (vta) to nucleus accumbens (nac) is involved in the motivation and preference for food. |
2021-05-14 |
2023-08-13 |
human |
| Yanjun Meng, Hong Li, Junjie Wang, Yong Xu, Binquan Wan. Cognitive behavioral therapy for patients with mild to moderate depression: Treatment effects and neural mechanisms. Journal of psychiatric research. vol 136. 2021-05-14. PMID:33631654. |
at the baseline, mri data revealed abnormalities in the hippocampus and nucleus accumbens (nac) of patients with mmd, e.g., smaller gray matter volumes of the hippocampus and nucleus accumbens (nac), as well as weaker functional connectivity between nac and the posterior cingulate cortex/precuneus. |
2021-05-14 |
2023-08-13 |
Not clear |
| Xugang Shi, Yunxiao Li, Peng Yan, Yuhui Shi, Jianghua La. Weighted gene co-expression network analysis to explore the mechanism of heroin addiction in human nucleus accumbens. Journal of cellular biochemistry. vol 121. issue 2. 2021-05-10. PMID:31692007. |
the purpose of the study was to identify the regulatory mechanism of the nucleus accumbens (nac) in heroin dependence. |
2021-05-10 |
2023-08-13 |
human |
| Kevin M Manz, Dipanwita Ghose, Brandon D Turner, Anne Taylor, Jennifer Becker, Carrie A Grueter, Brad A Gruete. Calcium-Permeable AMPA Receptors Promote Endocannabinoid Signaling at Parvalbumin Interneuron Synapses in the Nucleus Accumbens Core. Cell reports. vol 32. issue 4. 2021-05-10. PMID:32726634. |
synaptic plasticity mechanisms within the nucleus accumbens (nac) mediate differential behavioral adaptations. |
2021-05-10 |
2023-08-13 |
Not clear |
| Zi-Xuan He, Yue-Yue Yin, Ke Xi, Zhen-Kai Xing, Jian-Bo Cao, Ting-Yu Liu, Lin Liu, Xiao-Xiao He, Hua-Li Yu, Xiao-Juan Zh. Nucleus Accumbens Tac1-Expressing Neurons Mediate Stress-Induced Anhedonia-like Behavior in Mice. Cell reports. vol 33. issue 5. 2021-05-07. PMID:33147466. |
herein, we identify a discrete circuit of tachykinin precursor 1 (tac1)-expressing neurons in the nucleus accumbens (nac) lateral shell, which project to ventral pallidum and contribute to stress-induced anhedonia-like behavior. |
2021-05-07 |
2023-08-13 |
mouse |
| Mingda Yang, Hui Ma, Meng Jia, Yijing Li, Degen Miao, Cailian Cui, Liuzhen W. The role of the nucleus accumbens OXR1 in cocaine-induced locomotor sensitization. Behavioural brain research. vol 379. 2021-05-03. PMID:31743729. |
the nucleus accumbens (nac) is known to play a key role in mediating this motivation. |
2021-05-03 |
2023-08-13 |
rat |
| Cai-N Cheng, Andrew Chih Wei Huang, Shaw-Jye W. Roles of nucleus accumbens shell and core in footshock-induced stress altering behavioral sensitization by methamphetamine in acquisition and testing: Running head: stress, nucleus accumbens, and behavioral sensitization. Behavioural brain research. vol 380. 2021-05-03. PMID:31846629. |
how the subregions of the nucleus accumbens (nac) shell and core and stress are involved in behavioral sensitization induced by psychostimulants remains unclear. |
2021-05-03 |
2023-08-13 |
Not clear |
| Dar'ya Y Pozhidayeva, Sean P Farris, Calla M Goeke, Evan J Firsick, Kayla G Townsley, Marina Guizzetti, Angela R Ozbur. Chronic Chemogenetic Stimulation of the Nucleus Accumbens Produces Lasting Reductions in Binge Drinking and Ameliorates Alcohol-Related Morphological and Transcriptional Changes. Brain sciences. vol 10. issue 2. 2021-05-03. PMID:32085427. |
we tested whether chronically manipulating nucleus accumbens (nac) activity (via clozapine-n-oxide (cno) and designer receptors exclusively activated by designer drugs (dreadd)) could produce lasting effects on ethanol binge-like drinking in mice selectively bred to drink to intoxication. |
2021-05-03 |
2023-08-13 |
mouse |
| Ashley E Smith, Kehinde O Ogunseye, Julia N DeBenedictis, Joanna Peris, James M Kasper, Jonathan D Homme. Glutamatergic projections from homeostatic to hedonic brain nuclei regulate intake of highly palatable food. Scientific reports. vol 10. issue 1. 2021-05-03. PMID:33328492. |
hedonic feeding is driven, in part, by the reinforcing properties of highly palatable food (hpf), which is mediated by the nucleus accumbens (nac). |
2021-05-03 |
2023-08-13 |
Not clear |
| Daniel J Christoffel, Jessica J Walsh, Boris D Heifets, Paul Hoerbelt, Sophie Neuner, Gordon Sun, Vinod K Ravikumar, Hemmings Wu, Casey H Halpern, Robert C Malenk. Input-specific modulation of murine nucleus accumbens differentially regulates hedonic feeding. Nature communications. vol 12. issue 1. 2021-05-03. PMID:33837200. |
here, we show that modulation of prefrontal cortex (pfc) and anterior paraventricular thalamus (apvt) excitatory inputs to the nucleus accumbens (nac), a key node of reward circuitry, has opposing effects on high fat intake in mice. |
2021-05-03 |
2023-08-13 |
mouse |
| Kadri Kõiv, Kai Tiitsaar, Karita Laugus, Jaanus Harr. Extracellular Dopamine Levels in Nucleus Accumbens after Chronic Stress in Rats with Persistently High vs. Low 50-kHz Ultrasonic Vocalization Response. Brain sciences. vol 11. issue 4. 2021-05-02. PMID:33917789. |
to examine whether these differential responses are associated with dopaminergic neurotransmission in the nucleus accumbens (nac), juvenile male wistar rats were categorized as of high or low positive affectivity (hc and lc, respectively), and after reaching adulthood, extracellular dopamine (da) levels in the nac shell were measured using in vivo microdialysis after three weeks of cvs. |
2021-05-02 |
2023-08-13 |
rat |