| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Deepak Chouhan, Ankit Uniyal, Anagha Gadepalli, Akhilesh, Vineeta Tiwari, Somesh Agrawal, Tapas Kumar Roy, Sneha Shaw, Narendra Purohit, Vinod Tiwar. Probing the Manipulated Neurochemical Drive in Alcohol Addiction and Novel Therapeutic Advancements. ACS chemical neuroscience. vol 11. issue 9. 2021-06-18. PMID:32243128. |
these changes occur in various regions of the brain including reward circuit such as the ventral tegmental area (vta), nucleus accumbens (nac), and prefrontal cortex. |
2021-06-18 |
2023-08-13 |
Not clear |
| Miguel Skirzewski, Marie E Cronin, Ricardo Murphy, Wambura Fobbs, Alexxai V Kravitz, Andres Buonann. ErbB4 Null Mice Display Altered Mesocorticolimbic and Nigrostriatal Dopamine Levels as well as Deficits in Cognitive and Motivational Behaviors. eNeuro. vol 7. issue 3. 2021-06-18. PMID:32354758. |
here, we report that extracellular steady-state levels of da are reduced in the medial prefrontal cortex (mpfc; -65%), hippocampus (-53%) and nucleus accumbens (nac; -35%), but are elevated in the dorsal striatum (+25%) of erbb4 knock-out mice (erbb4 kos) relative to wild-type controls. |
2021-06-18 |
2023-08-13 |
mouse |
| Joseph R Driscoll, Tanya L Wallace, Kasra A Mansourian, William J Martin, Elyssa B Margoli. Differential Modulation of Ventral Tegmental Area Circuits by the Nociceptin/Orphanin FQ System. eNeuro. vol 7. issue 5. 2021-06-18. PMID:32747458. |
n/ofq and its receptor, nop, are enriched in dopaminergic pathways, and intra-ventricular agonist delivery decreases dopamine levels in the dorsal striatum, nucleus accumbens (nac), and ventral tegmental area (vta). |
2021-06-18 |
2023-08-13 |
rat |
| Andrew F Scheyer, Milene Borsoi, Anne-Laure Pelissier-Alicot, Olivier J J Manzon. Maternal Exposure to the Cannabinoid Agonist WIN 55,12,2 during Lactation Induces Lasting Behavioral and Synaptic Alterations in the Rat Adult Offspring of Both Sexes. eNeuro. vol 7. issue 5. 2021-06-18. PMID:32868310. |
these behavioral changes were paralleled by a specific loss of endocannabinoid-mediated long-term depression (ecb-ltd) in the pfc and nucleus accumbens (nac), while other forms of synaptic plasticity remained intact. |
2021-06-18 |
2023-08-13 |
rat |
| Nadine Eijsker, Guido van Wingen, Ruud Smolders, Dirk J A Smit, Damiaan Deny. Exploring the Role of the Nucleus Accumbens in Adaptive Behavior Using Concurrent Intracranial and Extracranial Electrophysiological Recordings in Humans. eNeuro. vol 7. issue 6. 2021-06-18. PMID:33168620. |
recent human electrophysiological evidence implicated θ-band communication between the nucleus accumbens (nac) and frontal and parietal cortex in cognitive flexibility. |
2021-06-18 |
2023-08-13 |
human |
| Luis A Trujillo-Villarreal, Viktor J Romero-Díaz, Iván Alberto Marino-Martínez, Lizeth Fuentes-Mera, Marco Antonio Ponce-Camacho, Gabriel A Devenyi, M Mallar Chakravarty, Alberto Camacho-Morales, Eduardo E Garza-Villarrea. Maternal cafeteria diet exposure primes depression-like behavior in the offspring evoking lower brain volume related to changes in synaptic terminals and gliosis. Translational psychiatry. vol 11. issue 1. 2021-06-18. PMID:33446642. |
macrostructural dbm analysis showed reduction in the frontomesocorticolimbic circuit volume including the nucleus accumbens (nac), hippocampus, and prefrontal cortex. |
2021-06-18 |
2023-08-13 |
rat |
| Gang Lei, Fei Liu, Peng Liu, Tong Jiao, Liu Yang, Zheng Chu, Li-Sha Deng, Yan Li, Yong-Hui Dan. Does genetic mouse model of constitutive Hint1 deficiency exhibit schizophrenia-like behaviors? Schizophrenia research. vol 222. 2021-06-17. PMID:32439293. |
total glutamate was decreased in the medial prefrontal cortex, nucleus accumbens (nac), and hip of ko mice. |
2021-06-17 |
2023-08-13 |
mouse |
| Zahra Ebrahimi, Nazanin Kahvandi, Alireza Komaki, Seyed Asaad Karimi, Marzieh Naderishahab, Abdolrahman Sarih. The role of mGlu4 receptors within the nucleus accumbens in acquisition and expression of morphine-induced conditioned place preference in male rats. BMC neuroscience. vol 22. issue 1. 2021-06-17. PMID:33743609. |
several studies have shown that glutamate neurotransmission in the nucleus accumbens (nac) is required for the development of morphine-induced conditional place preference (cpp). |
2021-06-17 |
2023-08-13 |
rat |
| Yasaman Husseini, Alireza Mohammadi, Gila Pirzad Jahromi, Gholamhossein Meftahi, Hedayat Sahraei, Boshra Hate. The controlling role of nitric oxide within the shell of nucleus accumbens in the stress-induced metabolic disturbance. Archives of physiology and biochemistry. vol 127. issue 1. 2021-06-15. PMID:31094227. |
the involvement of the nitricergic system within the shell part of the nucleus accumbens (nac) was evaluated in the metabolic disturbances due to stress. |
2021-06-15 |
2023-08-13 |
Not clear |
| José Pedro Prieto, Ximena López Hill, Jessika Urbanavicius, Verónica Sanchez, Xavier Nadal, Cecilia Scorz. Cannabidiol Prevents the Expression of the Locomotor Sensitization and the Metabolic Changes in the Nucleus Accumbens and Prefrontal Cortex Elicited by the Combined Administration of Cocaine and Caffeine in Rats. Neurotoxicity research. vol 38. issue 2. 2021-06-14. PMID:32415526. |
the effect of cbd on putative alterations in the metabolic activity of the medial prefrontal cortex (mpfc) and nucleus accumbens (nac), and its respective subregions (cingulated, prelimbic, and infralimbic cortices, and nac core and shell) associated to the behavioral response, was also investigated. |
2021-06-14 |
2023-08-13 |
rat |
| Yao Q Wang, Yanhua H Huang, Saju Balakrishnan, Lidong Liu, Yu Tian Wang, Eric J Nestler, Oliver M Schlüter, Yan Don. AMPA and NMDA Receptor Trafficking at Cocaine-Generated Synapses. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 41. issue 9. 2021-06-11. PMID:33436529. |
cocaine experience generates ampa receptor (ampar)-silent synapses in the nucleus accumbens (nac), which are thought to be new synaptic contacts enriched in glun2b-containing nmda receptors (nmdars). |
2021-06-11 |
2023-08-13 |
mouse |
| Tracy L Fetterly, Max F Oginsky, Allison M Nieto, Yanaira Alonso-Caraballo, Zuleirys Santana-Rodriguez, Carrie R Ferrari. Insulin Bidirectionally Alters NAc Glutamatergic Transmission: Interactions between Insulin Receptor Activation, Endogenous Opioids, and Glutamate Release. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 41. issue 11. 2021-06-11. PMID:33514676. |
human fmri studies show that insulin influences brain activity in regions that mediate reward and motivation, including the nucleus accumbens (nac). |
2021-06-11 |
2023-08-13 |
human |
| Christopher K Lafferty, Jonathan P Brit. Off-Target Influences of Arch-Mediated Axon Terminal Inhibition on Network Activity and Behavior. Frontiers in neural circuits. vol 14. 2021-06-10. PMID:32269514. |
here, we compare axon terminal and cell body photoinhibition of nucleus accumbens (nac) afferents to test the utility of these approaches for uncovering pathway-specific contributions of neural circuits to behavior. |
2021-06-10 |
2023-08-13 |
Not clear |
| Le Xu, Jun Nan, Yan La. The Nucleus Accumbens: A Common Target in the Comorbidity of Depression and Addiction. Frontiers in neural circuits. vol 14. 2021-06-10. PMID:32694984. |
the nucleus accumbens (nac) has long been considered a key brain region for regulating many behaviors, especially those related to depression and addiction. |
2021-06-10 |
2023-08-13 |
Not clear |
| C W Wallace, M C Loudermilt, S C Fordah. Effect of fasting on dopamine neurotransmission in subregions of the nucleus accumbens in male and female mice. Nutritional neuroscience. 2021-06-10. PMID:33297887. |
however, functional compartments in the nucleus accumbens (nac) influencing these effects are not well characterized, and sex comparisons have not been made. |
2021-06-10 |
2023-08-13 |
mouse |
| Thomas Contesse, Loïc Broussot, Hugo Fofo, Peter Vanhoutte, Sebastian P Fernandez, Jacques Bari. Dopamine and glutamate receptors control social stress-induced striatal ERK1/2 activation. Neuropharmacology. vol 190. 2021-06-09. PMID:33781778. |
the nucleus accumbens (nac) showed marked increases in perk1/2 following both acute and chronic social stress compared to the dorsal striatum. |
2021-06-09 |
2023-08-13 |
mouse |
| Keith A Misquitta, Amy Miles, Thomas D Prevot, Jaime K Knoch, Corey Fee, Dwight F Newton, Jacob Ellegood, Jason P Lerch, Etienne Sibille, Yuliya S Nikolova, Mounira Banas. Reduced anterior cingulate cortex volume induced by chronic stress correlates with increased behavioral emotionality and decreased synaptic puncta density. Neuropharmacology. vol 190. 2021-06-09. PMID:33864799. |
clinical and preclinical studies report that chronic stress induces behavioral deficits as well as volumetric and synaptic alterations in corticolimbic brain regions including the anterior cingulate cortex (acc), amygdala (amy), nucleus accumbens (nac) and hippocampus (hpc). |
2021-06-09 |
2023-08-13 |
Not clear |
| Elahe Khosrowabadi, Saeideh Karimi-Haghighi, Shole Jamali, Abbas Haghparas. Differential Roles of Intra-accumbal Orexin Receptors in Acquisition and Expression of Methamphetamine-Induced Conditioned Place Preference in the Rats. Neurochemical research. vol 45. issue 9. 2021-06-08. PMID:32643036. |
a large amount of document has revealed that the orexin system in the reward circuity, including the nucleus accumbens (nac), contributes to the modification of drug reinforcement. |
2021-06-08 |
2023-08-13 |
rat |
| Denis Burdako. How orexin signals bias action: Hypothalamic and accumbal circuits. Brain research. vol 1731. 2021-06-07. PMID:30205111. |
this review outlines and puts into broader context recent examples of orexin circuit analyses in the lateral hypothalamus (lh) and the nucleus accumbens (nac), two brain regions clasically implicated in context-appropriate actions. |
2021-06-07 |
2023-08-13 |
Not clear |
| Reza Fartootzadeh, Hojjatallah Alaei, Parham Reis. Mutual assistance of nucleus accumbens cannabinoid receptor-1 and orexin receptor-2 in response to nicotine: a single-unit study. Research in pharmaceutical sciences. vol 16. issue 2. 2021-06-05. PMID:34084204. |
the nucleus accumbens (nac) express both orexin-2 receptor (ox2r) and cannabinoid receptor type 1 (cb1r). |
2021-06-05 |
2023-08-13 |
Not clear |