| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Stephan Lammel, Daniela I Ion, Jochen Roeper, Robert C Malenk. Projection-specific modulation of dopamine neuron synapses by aversive and rewarding stimuli. Neuron. vol 70. issue 5. 2011-08-23. PMID:21658580. |
administration of cocaine selectively modified excitatory synapses on da cells projecting to nucleus accumbens (nac) medial shell while an aversive stimulus selectively modified synapses on da cells projecting to medial prefrontal cortex. |
2011-08-23 |
2023-08-12 |
mouse |
| José Antonio Fuentealba, Katia Gysling, María Estela André. Repeated treatment with the κ-opioid agonist U-69593 increases K+-stimulated dopamine release in the rat medial prefrontal cortex. Synapse (New York, N.Y.). vol 64. issue 12. 2011-08-15. PMID:20939060. |
acute activation of κ-opioid receptors (kor) decreases dopamine (da) extracellular levels in both the medial prefrontal cortex (mpfc) and the nucleus accumbens (nac). |
2011-08-15 |
2023-08-12 |
rat |
| Chun-Mei Xu, Jun Wang, Ping Wu, Yan-Xue Xue, Wei-Li Zhu, Qian-Qian Li, Hai-Feng Zhai, Jie Shi, Lin L. Glycogen synthase kinase 3β in the nucleus accumbens core is critical for methamphetamine-induced behavioral sensitization. Journal of neurochemistry. vol 118. issue 1. 2011-08-12. PMID:21517846. |
we recently found that gsk-3β activity in the nucleus accumbens (nac) core is critically involved in cocaine-induced behavioral sensitization. |
2011-08-12 |
2023-08-12 |
rat |
| Laurent Coque, Shibani Mukherjee, Jun-Li Cao, Sade Spencer, Marian Marvin, Edgardo Falcon, Michelle M Sidor, Shari G Birnbaum, Ami Graham, Rachael L Neve, Elizabeth Gordon, Angela R Ozburn, Matthew S Goldberg, Ming-Hu Han, Donald C Cooper, Colleen A McClun. Specific role of VTA dopamine neuronal firing rates and morphology in the reversal of anxiety-related, but not depression-related behavior in the ClockΔ19 mouse model of mania. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 36. issue 7. 2011-08-10. PMID:21430648. |
furthermore, lithium treatment reduces nucleus accumbens (nac) dopamine levels selectively in the mutant mice. |
2011-08-10 |
2023-08-12 |
mouse |
| Wei Wang, Dalong Sun, Bin Pan, Christopher J Roberts, Xinglai Sun, Cecilia J Hillard, Qing-song Li. Deficiency in endocannabinoid signaling in the nucleus accumbens induced by chronic unpredictable stress. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 35. issue 11. 2011-08-08. PMID:20664582. |
the nucleus accumbens (nac) is a critical component of the reward circuitry, and dysfunction of the nac may account for anhedonia and other symptoms of depression. |
2011-08-08 |
2023-08-12 |
mouse |
| Robert W Gear, Jon D Levin. Nucleus accumbens facilitates nociception. Experimental neurology. vol 229. issue 2. 2011-08-05. PMID:21458450. |
we have previously demonstrated an opioid link in nucleus accumbens (nac) that mediates antinociception produced by a novel ascending pain modulation pathway. |
2011-08-05 |
2023-08-12 |
rat |
| Frederic Ambroggi, Ali Ghazizadeh, Saleem M Nicola, Howard L Field. Roles of nucleus accumbens core and shell in incentive-cue responding and behavioral inhibition. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 18. 2011-08-05. PMID:21543612. |
the nucleus accumbens (nac) is involved in many reward-related behaviors. |
2011-08-05 |
2023-08-12 |
rat |
| S B Kombian, O A Phillip. In vitro electrophysiological investigations of the acute effects of linezolid and novel oxazolidinones on central nervous system neurons. Neuroscience. vol 180. 2011-08-04. PMID:21296129. |
using in vitro slice preparations of the rat nucleus accumbens (nac) and hippocampus, we examined the effects of linezolid and the potent antibacterial triazolyl oxazolidinones, ph027, ph036, ph084 and ph108 on synaptic transmission and neuronal excitability recorded in voltage or current clamp mode. |
2011-08-04 |
2023-08-12 |
rat |
| Yanfang Xia, Joseph R Driscoll, Linda Wilbrecht, Elyssa B Margolis, Howard L Fields, Gregory O Hjelmsta. Nucleus accumbens medium spiny neurons target non-dopaminergic neurons in the ventral tegmental area. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 21. 2011-08-04. PMID:21613494. |
the midbrain ventral tegmental area (vta) projection to the nucleus accumbens (nac) is implicated in motivation and reinforcement. |
2011-08-04 |
2023-08-12 |
rat |
| Justin T Gass, Courtney M Sinclair, Richard M Cleva, John J Widholm, M Foster Oliv. Alcohol-seeking behavior is associated with increased glutamate transmission in basolateral amygdala and nucleus accumbens as measured by glutamate-oxidase-coated biosensors. Addiction biology. vol 16. issue 2. 2011-07-20. PMID:21054692. |
male wistar rats were implanted with indwelling jugular vein catheters and intracerebral guide cannula aimed at the basolateral amygdala (bla) or nucleus accumbens (nac) core, and then trained to self-administer alcohol intravenously. |
2011-07-20 |
2023-08-12 |
rat |
| Mina Ito, Taku Nagai, Hiroyuki Mizoguchi, Kosuke Sato, Minoru Hayase, Noboru Otsuka, Ayumi Fukakusa, Nozomi Kumagai, Hyoung-Chun Kim, Toshitaka Nabeshima, Kazuhiro Takuma, Kiyofumi Yamad. Activation of post-synaptic dopamine D₁ receptors promotes the release of tissue plasminogen activator in the nucleus accumbens via PKA signaling. Journal of neurochemistry. vol 103. issue 6. 2011-07-19. PMID:17944865. |
we have previously demonstrated that tissue plasminogen activator (tpa) plays an important role through the conversion of plasminogen to plasmin in the release of dopamine in the nucleus accumbens (nac) evoked by depolarization or the systemic administration of drugs of abuse such as morphine and nicotine. |
2011-07-19 |
2023-08-12 |
Not clear |
| Richard Exley, Nicolas Maubourguet, Vincent David, Raphaël Eddine, Alexis Evrard, Stéphanie Pons, Fabio Marti, Sarah Threlfell, Pierre Cazala, J Michael McIntosh, Jean-Pierre Changeux, Uwe Maskos, Stephanie J Cragg, Philippe Faur. Distinct contributions of nicotinic acetylcholine receptor subunit alpha4 and subunit alpha6 to the reinforcing effects of nicotine. Proceedings of the National Academy of Sciences of the United States of America. vol 108. issue 18. 2011-07-15. PMID:21502501. |
using subunit-specific knockout mice and targeted lentiviral re-expression, we have determined the subunit dependence of intracranial nicotine self-administration (icsa) into the vta and the effects of nicotine on dopamine (da) neuron excitability in the vta and on da transmission in the nucleus accumbens (nac). |
2011-07-15 |
2023-08-12 |
mouse |
| H Franke, C Schepper, P Illes, U Krüge. Involvement of P2X and P2Y receptors in microglial activation in vivo. Purinergic signalling. vol 3. issue 4. 2011-07-14. PMID:18404456. |
in the rat nucleus accumbens (nac), the involvement of p2x and p2y receptors in the generation of microglial reaction in vivo was investigated. |
2011-07-14 |
2023-08-12 |
rat |
| Helga Höifödt Lidö, Mia Ericson, Hugh Marston, Bo Söderpal. A role for accumbal glycine receptors in modulation of dopamine release by the glycine transporter-1 inhibitor org25935. Frontiers in psychiatry. vol 2. 2011-07-14. PMID:21556278. |
accumbal glycine modulates basal and ethanol-induced dopamine levels in the nucleus accumbens (nac) as well as voluntary ethanol consumption. |
2011-07-14 |
2023-08-12 |
rat |
| Billy T Chen, Jyoti C Patel, Kimberly A Moran, Margaret E Ric. Differential calcium dependence of axonal versus somatodendritic dopamine release, with characteristics of both in the ventral tegmental area. Frontiers in systems neuroscience. vol 5. 2011-07-14. PMID:21716634. |
here, we evaluated the ca(2+) dependence of da release in the vta and nucleus accumbens (nac) shell for comparison with that in the snc and dorsal striatum. |
2011-07-14 |
2023-08-12 |
Not clear |
| Karima Chergu. Dopamine induces a GluN2A-dependent form of long-term depression of NMDA synaptic responses in the nucleus accumbens. Neuropharmacology. vol 60. issue 6. 2011-07-12. PMID:21295045. |
natural rewards and addictive drugs are believed to exert their reinforcing actions by influencing synaptic plasticity in reward-related brain regions such as the nucleus accumbens (nac). |
2011-07-12 |
2023-08-12 |
mouse |
| Yin Shou, Ying-qian Zhao, Ming-shu Xu, Lin-bao G. [Effects of repeated electroacupuncture on gene expression of cannabinoid receptor-1 and dopamine 1 receptor in nucleus accumbens-caudate nucleus region in inflammatory-pain rats]. Zhen ci yan jiu = Acupuncture research. vol 36. issue 1. 2011-07-12. PMID:21585053. |
to observe the effect of repeated electroacupuncture (ea) on the expression of cannabinoid receptor-1 (cb 1) mrrna and dopamine 1 receptor (d 1) mrna in nucleus accumbens (nac)-caudate nucleus (cn) region in inflammatory-pain rats, so as to study its underlying mechanism in analgesia. |
2011-07-12 |
2023-08-12 |
rat |
| Tanja Kivinummi, Kristiina Kaste, Tomi Rantamäki, Eero Castrén, Liisa Ahte. Alterations in BDNF and phospho-CREB levels following chronic oral nicotine treatment and its withdrawal in dopaminergic brain areas of mice. Neuroscience letters. vol 491. issue 2. 2011-07-05. PMID:21232579. |
bdnf levels were not altered by chronic nicotine treatment, but they were significantly increased in the nucleus accumbens (nac) after 24h and 29 days of nicotine abstinence and in the ventral tegmental area (vta) and substantia nigra after 29 days of nicotine abstinence. |
2011-07-05 |
2023-08-12 |
mouse |
| Christopher M Stern, Jessie I Luoma, John Meitzen, Paul G Mermelstei. Corticotropin releasing factor-induced CREB activation in striatal neurons occurs via a novel Gβγ signaling pathway. PloS one. vol 6. issue 3. 2011-07-05. PMID:21448293. |
one of these regions is the striatum, including the nucleus accumbens (nac). |
2011-07-05 |
2023-08-12 |
Not clear |
| Ji-Ye Sun, Jing-Yu Yang, Fang Wang, Yue Hou, Ying-Xu Dong, Chun-Fu W. GABAA receptors in VTA mediate the morphine-induced release of ascorbic acid in rat nucleus accumbens. Brain research. vol 1368. 2011-06-30. PMID:20965157. |
local perfusion of morphine produces increased levels of extracellular ascorbic acid (aa) in the nucleus accumbens (nac) of freely moving rats. |
2011-06-30 |
2023-08-12 |
rat |