| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Alessandra Lintas, Ning Chi, Nicole M Lauzon, Stephanie F Bishop, Shervin Gholizadeh, Ninglei Sun, Huibing Tan, Steven R Laviolett. Identification of a dopamine receptor-mediated opiate reward memory switch in the basolateral amygdala-nucleus accumbens circuit. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 31. 2011-10-11. PMID:21813678. |
the basolateral amygdala (bla), ventral tegmental area (vta), and nucleus accumbens (nac) play central roles in the processing of opiate-related associative reward learning and memory. |
2011-10-11 |
2023-08-12 |
rat |
| Jessy John, Rohit Manchand. Modulation of synaptic potentials and cell excitability by dendritic KIR and KAs channels in nucleus accumbens medium spiny neurons: a computational study. Journal of biosciences. vol 36. issue 2. 2011-10-07. PMID:21654085. |
the nucleus accumbens (nac), a critical structure of the brain reward circuit, is implicated in normal goal-directed behaviour and learning as well as pathological conditions like schizophrenia and addiction. |
2011-10-07 |
2023-08-12 |
Not clear |
| Xiao-Dong Liu, Zhuo Liu, Qing-Yao Kong, Jian-Jun Zhang, Yao Wang, Long-Chuan Y. Different physiological properties of spontaneous excitatory postsynaptic currents in nucleus accumbens shell neurons between adult and juvenile rats. Neuroscience letters. vol 496. issue 2. 2011-09-29. PMID:21501660. |
studies have demonstrated the changes of the physiological characteristics of nucleus accumbens (nac) neurons with the postnatal development of rats. |
2011-09-29 |
2023-08-12 |
rat |
| Kensuke Kimura, Takatoshi Hikida, Satoshi Yawata, Takashi Yamaguchi, Shigetada Nakanish. Pathway-specific engagement of ephrinA5-EphA4/EphA5 system of the substantia nigra pars reticulata in cocaine-induced responses. Proceedings of the National Academy of Sciences of the United States of America. vol 108. issue 24. 2011-09-29. PMID:21628570. |
the nucleus accumbens (nac) serves as a key neural substrate that controls acute and adaptive behavioral responses to cocaine administration. |
2011-09-29 |
2023-08-12 |
mouse |
| Ming Xiong, Jingyuan Li, Jiang H Ye, Chunxiang Zhan. Upregulation of DeltaFosB by propofol in rat nucleus accumbens. Anesthesia and analgesia. vol 113. issue 2. 2011-09-28. PMID:21642609. |
in this study, we determined the effect of propofol on the expression of deltafosb in rat nucleus accumbens (nac) and the potential mechanism involved. |
2011-09-28 |
2023-08-12 |
rat |
| Wen-han Hu, Yong-feng Bi, Kai Zhang, Fan-gang Meng, Jian-guo Zhan. High-frequency electrical stimulation in the nucleus accumbens of morphine-treated rats suppresses neuronal firing in reward-related brain regions. Medical science monitor : international medical journal of experimental and clinical research. vol 17. issue 6. 2011-09-22. PMID:21629184. |
previous studies have reported that high-frequency stimulation (hfs) in the nucleus accumbens (nac) is a potential treatment modality for drug craving and relapse. |
2011-09-22 |
2023-08-12 |
rat |
| Duo Zhang, Dong-Xiao Yang, Chun-Xiao Yang, Guang-Wen Zhang, He-Ren Gao, Ye Zhai, Run-Sheng Jiao, Ying Zhang, Hui Zhang, Yu Liang, Man-Ying X. Effects of norepinephrine on the electrical activities of pain-related neurons in the rat nucleus accumbens. Pharmacological reports : PR. vol 63. issue 2. 2011-09-16. PMID:21602596. |
this study examined the effects of norepinephrine (ne) and phentolamine on the electrical activities of pain-excited neurons (pens) and pain-inhibited neurons (pins) in the nucleus accumbens (nac) of wistar rats. |
2011-09-16 |
2023-08-12 |
rat |
| Marina E Wol. Regulation of AMPA receptor trafficking in the nucleus accumbens by dopamine and cocaine. Neurotoxicity research. vol 18. issue 3-4. 2011-09-15. PMID:20361291. |
nucleus accumbens (nac) neurons are excited primarily by ampa-type glutamate receptors (ampar). |
2011-09-15 |
2023-08-12 |
rat |
| Richard J Beninger, Tyson W Baker, Matthew M Florczynski, Tomek J Banasikowsk. Regional differences in the action of antipsychotic drugs: implications for cognitive effects in schizophrenic patients. Neurotoxicity research. vol 18. issue 3-4. 2011-09-15. PMID:20376711. |
evidence from immediate early gene immunohistochemical, electrophysiological, microdialysis, imaging, and behavioral studies suggests that typical apds preferentially affect the nucleus accumbens (nac) and the dorsal striatum while atypical apds preferentially affect the nac and medial prefrontal cortex (pfc). |
2011-09-15 |
2023-08-12 |
Not clear |
| Megan St Peters, Elise Demeter, Cindy Lustig, John P Bruno, Martin Sarte. Enhanced control of attention by stimulating mesolimbic-corticopetal cholinergic circuitry. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 26. 2011-09-13. PMID:21715641. |
because stimulation of nmda receptors in the shell of the nucleus accumbens activates pfc cholinergic neurotransmission, a second experiment demonstrated that bilateral infusions of nmda into the nac shell, but not core, improved dsat performance to levels observed in the absence of a distractor. |
2011-09-13 |
2023-08-12 |
rat |
| Patrick E Rothwell, Saïd Kourrich, Mark J Thoma. Synaptic adaptations in the nucleus accumbens caused by experiences linked to relapse. Biological psychiatry. vol 69. issue 11. 2011-09-12. PMID:21329910. |
excitatory synaptic transmission in the nucleus accumbens (nac) regulates the reinstatement of drug seeking, an animal model of relapse in human drug addicts. |
2011-09-12 |
2023-08-12 |
human |
| Juhyun Kim, Bong-Hyun Park, Joo Han Lee, Sang Ki Park, Joung-Hun Ki. Cell type-specific alterations in the nucleus accumbens by repeated exposures to cocaine. Biological psychiatry. vol 69. issue 11. 2011-09-12. PMID:21377654. |
the nucleus accumbens (nac) is a brain region critically involved in psychostimulant-induced neuroadaptations. |
2011-09-12 |
2023-08-12 |
Not clear |
| Hyung Wook Nam, Moonnoh R Lee, Yu Zhu, Jinhua Wu, David J Hinton, Sun Choi, Taehyun Kim, Nora Hammack, Jerry C P Yin, Doo-Sup Cho. Type 1 equilibrative nucleoside transporter regulates ethanol drinking through accumbal N-methyl-D-aspartate receptor signaling. Biological psychiatry. vol 69. issue 11. 2011-09-12. PMID:21489406. |
this phenotype of ent1(-/-) mice appears to be correlated with increased glutamate levels in the nucleus accumbens (nac). |
2011-09-12 |
2023-08-12 |
mouse |
| Segev Barak, Sebastien Carnicella, Quinn V Yowell, Dorit Ro. Glial cell line-derived neurotrophic factor reverses alcohol-induced allostasis of the mesolimbic dopaminergic system: implications for alcohol reward and seeking. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 27. 2011-09-09. PMID:21734280. |
we previously showed that infusion of glial cell line-derived neurotrophic factor (gdnf) into the ventral tegmental area (vta) rapidly reduces alcohol intake and relapse (carnicella et al., 2008, 2009a), and increases dopamine (da) levels in the nucleus accumbens (nac) of alcohol-naive rats (wang et al., 2010). |
2011-09-09 |
2023-08-12 |
rat |
| Michael Lazarus, Hai-Ying Shen, Yoan Cherasse, Wei-Min Qu, Zhi-Li Huang, Caroline E Bass, Raphaelle Winsky-Sommerer, Kazue Semba, Bertil B Fredholm, Detlev Boison, Osamu Hayaishi, Yoshihiro Urade, Jiang-Fan Che. Arousal effect of caffeine depends on adenosine A2A receptors in the shell of the nucleus accumbens. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 27. 2011-09-09. PMID:21734299. |
using selective gene deletion strategies based on the cre/loxp technology in mice and focal rna interference to silence the expression of a(2a)rs in rats by local infection with adeno-associated virus carrying short-hairpin rna, we report that the a(2a)rs in the shell region of the nucleus accumbens (nac) are responsible for the effect of caffeine on wakefulness. |
2011-09-09 |
2023-08-12 |
mouse |
| Mei Han, Xu-Feng Huang, Chao Den. Aripiprazole differentially affects mesolimbic and nigrostriatal dopaminergic transmission: implications for long-term drug efficacy and low extrapyramidal side-effects. The international journal of neuropsychopharmacology. vol 12. issue 7. 2011-09-06. PMID:19203411. |
aripiprazole significantly increased d2 receptor mrna expression and decreased tyrosine hydroxylase (th) mrna expression in the ventral tegmental area (vta) after 1- and 12-wk treatment, but had no effect in substantia nigra (sn) and nucleus accumbens (nac). |
2011-09-06 |
2023-08-12 |
Not clear |
| Matthew B Wilkinson, Caroline Dias, Jane Magida, Michelle Mazei-Robison, MaryKay Lobo, Pamela Kennedy, David Dietz, Herbert Covington, Scott Russo, Rachael Neve, Subroto Ghose, Carol Tamminga, Eric J Nestle. A novel role of the WNT-dishevelled-GSK3β signaling cascade in the mouse nucleus accumbens in a social defeat model of depression. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 25. 2011-09-02. PMID:21697359. |
based on earlier gene expression and chromatin array data, we identified the protein, dishevelled (dvl)-2, as being regulated in the nucleus accumbens (nac), a key brain reward region, in the mouse social defeat model of depression. |
2011-09-02 |
2023-08-12 |
mouse |
| Garret D Stuber, Dennis R Sparta, Alice M Stamatakis, Wieke A van Leeuwen, Juanita E Hardjoprajitno, Saemi Cho, Kay M Tye, Kimberly A Kempadoo, Feng Zhang, Karl Deisseroth, Antonello Bonc. Excitatory transmission from the amygdala to nucleus accumbens facilitates reward seeking. Nature. vol 475. issue 7356. 2011-08-30. PMID:21716290. |
the bla projection to the nucleus accumbens (nac) is thought to modulate cue-triggered motivated behaviours, but our understanding of the interaction between these two brain regions has been limited by the inability to manipulate neural-circuit elements of this pathway selectively during behaviour. |
2011-08-30 |
2023-08-12 |
mouse |
| Narasimha M Midde, Adrian M Gomez, Steven B Harrod, Jun Zh. Genetically expressed HIV-1 viral proteins attenuate nicotine-induced behavioral sensitization and alter mesocorticolimbic ERK and CREB signaling in rats. Pharmacology, biochemistry, and behavior. vol 98. issue 4. 2011-08-24. PMID:21420997. |
further, we examined camp response element binding protein (creb) and extracellular regulated kinase (erk1/2) signaling in the prefrontal cortex (pfc), nucleus accumbens (nac) and ventral tegmental area (vta). |
2011-08-24 |
2023-08-12 |
rat |
| Travis E Brown, Brian R Lee, Ping Mu, Deveroux Ferguson, David Dietz, Yoshinori N Ohnishi, Ying Lin, Anna Suska, Masago Ishikawa, Yanhua H Huang, Haowei Shen, Peter W Kalivas, Barbara A Sorg, R Suzanne Zukin, Eric J Nestler, Yan Dong, Oliver M Schlüte. A silent synapse-based mechanism for cocaine-induced locomotor sensitization. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 22. 2011-08-23. PMID:21632938. |
here, we further analyzed the role of cocaine-induced silent synapses in the nucleus accumbens (nac) shell and their contribution to the development of locomotor sensitization. |
2011-08-23 |
2023-08-12 |
rat |