| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Tracey A Martin, Subramaniam Jayanthi, Michael T McCoy, Christie Brannock, Bruce Ladenheim, Tiffany Garrett, Elin Lehrmann, Kevin G Becker, Jean Lud Cade. Methamphetamine causes differential alterations in gene expression and patterns of histone acetylation/hypoacetylation in the rat nucleus accumbens. PloS one. vol 7. issue 3. 2012-08-03. PMID:22470541. |
little is known about the effects of meth on gene expression and epigenetic modifications in the rat nucleus accumbens (nac). |
2012-08-03 |
2023-08-12 |
rat |
| Courtney M Sinclair, Richard M Cleva, Lauren E Hood, M Foster Olive, Justin T Gas. mGluR5 receptors in the basolateral amygdala and nucleus accumbens regulate cue-induced reinstatement of ethanol-seeking behavior. Pharmacology, biochemistry, and behavior. vol 101. issue 3. 2012-08-02. PMID:22296815. |
the purpose of the present study was to determine if local blockade of mglur5 receptors in the basolateral amygdala (bla) and/or the nucleus accumbens (nac), two brain regions known to be involved in stimulus-reward associations, attenuate the reinstatement of ethanol-seeking behavior induced by ethanol-paired cues. |
2012-08-02 |
2023-08-12 |
rat |
| Jing Liang, Xigeng Zheng, Jihuan Chen, Yingying Li, Xiaoli Xing, Yunjing Bai, Yingcong L. Roles of BDNF, dopamine D(3) receptors, and their interactions in the expression of morphine-induced context-specific locomotor sensitization. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 21. issue 11. 2012-08-01. PMID:21277174. |
previous studies indicated that the dopamine d(3) receptor (drd3) might be involved in the expression of drug-conditioned responses in rats, and brain-derived neurotrophic factor (bdnf) could modulate drd3 expression in the nucleus accumbens (nac). |
2012-08-01 |
2023-08-12 |
rat |
| Laura J Sim-Selley, Michael P Cassidy, Antonino Sparta, Venetia Zachariou, Eric J Nestler, Dana E Selle. Effect of ΔFosB overexpression on opioid and cannabinoid receptor-mediated signaling in the nucleus accumbens. Neuropharmacology. vol 61. issue 8. 2012-08-01. PMID:21907220. |
the stable transcription factor Δfosb is induced in the nucleus accumbens (nac) by chronic exposure to several drugs of abuse, and transgenic expression of Δfosb in the striatum enhances the rewarding properties of morphine and cocaine. |
2012-08-01 |
2023-08-12 |
mouse |
| Kathryn M Gill, Anthony A Grac. Heterogeneous processing of amygdala and hippocampal inputs in the rostral and caudal subregions of the nucleus accumbens. The international journal of neuropsychopharmacology. vol 14. issue 10. 2012-07-30. PMID:21211108. |
the nucleus accumbens (nac) receives converging input from a number of structures proposed to play a role in affective disorders. |
2012-07-30 |
2023-08-12 |
rat |
| Amy A Herrold, Robin M Voigt, T Celeste Napie. Brain region-selective cellular redistribution of mGlu5 but not GABA(B) receptors following methamphetamine-induced associative learning. Synapse (New York, N.Y.). vol 65. issue 12. 2012-07-30. PMID:21780181. |
to fill this gap, this study used methamphetamine (meth)-induced cpp in rats to ascertain if receptor changes occur in limbic brain regions that regulate drug-seeking, the medial prefrontal cortex (mpfc), nucleus accumbens (nac), and ventral pallidum (vp). |
2012-07-30 |
2023-08-12 |
rat |
| Shunsuke Tanahashi, Satoshi Yamamura, Masanori Nakagawa, Eishi Motomura, Motohiro Okad. Dopamine D2 and serotonin 5-HT1A receptors mediate the actions of aripiprazole in mesocortical and mesoaccumbens transmission. Neuropharmacology. vol 62. issue 2. 2012-07-27. PMID:21925189. |
to address this, we examined the effects of systemic and local administrations of aripiprazole on extracellular levels of dopamine and gaba in medial prefrontal cortex (mpfc), nucleus accumbens (nac), and anterior (avta) and posterior (pvta) ventral tegmental areas. |
2012-07-27 |
2023-08-12 |
Not clear |
| Samuel B Kombian, Kethireddy V V Ananthalakshmi, Jeffrey A Zidichouski, Tarek M Sale. Cocaine sensitization does not alter SP effects on locomotion or excitatory synaptic transmission in the NAc of rats. Neuropharmacology. vol 62. issue 2. 2012-07-27. PMID:21930135. |
substance p (sp) and cocaine employ similar mechanisms to modify excitatory synaptic transmission in the nucleus accumbens (nac), a region implicated in substance abuse. |
2012-07-27 |
2023-08-12 |
rat |
| Xingjie Ping, Yaoying Ma, Yijing Li, Chong Qi, Xiaowei Sun, Xiufang Lv, Cailian Cu. Essential role of protein kinase C in morphine-induced rewarding memory. Neuropharmacology. vol 62. issue 2. 2012-07-27. PMID:22023848. |
we found a significant translocation of pkcs from cytosol to membrane component in nucleus accumbens (nac) of morphine-conditioned rats in a dose-dependent manner. |
2012-07-27 |
2023-08-12 |
rat |
| In-Jee You, Yang-Hee Jung, Min-Jung Kim, Seung-Hwan Kwon, Sa-Ik Hong, Seok-Yong Lee, Choon-Gon Jan. Alterations in the emotional and memory behavioral phenotypes of transient receptor potential vanilloid type 1-deficient mice are mediated by changes in expression of 5-HT₁A, GABA(A), and NMDA receptors. Neuropharmacology. vol 62. issue 2. 2012-07-27. PMID:22074644. |
binding of [(3)h]-8-oh-dpat was significantly higher in the frontal associated cortex (fra), nucleus accumbens (nac), and the cingulate cortex (cc) of trpv1ko mice than wt mice, while the expression of 5-ht(1a) receptors was higher in the fra, nac, and cortex of trpv1ko mice than wt mice. |
2012-07-27 |
2023-08-12 |
mouse |
| Thorfinn T Riday, Barry E Kosofsky, C J Malang. The rewarding and locomotor-sensitizing effects of repeated cocaine administration are distinct and separable in mice. Neuropharmacology. vol 62. issue 4. 2012-07-27. PMID:22197517. |
expression of ampa receptor subunits (glur1 and glur2) and cre binding protein (creb) was measured in the ventral tegmental area (vta), dorsolateral striatum (str) and nucleus accumbens (nac) before and after a sensitizing regimen of cocaine, with and without icss. |
2012-07-27 |
2023-08-12 |
mouse |
| Shanna L Resendez, Morgan Kuhnmuench, Tarin Krzywosinski, Brandon J Aragon. κ-Opioid receptors within the nucleus accumbens shell mediate pair bond maintenance. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 32. issue 20. 2012-07-27. PMID:22593047. |
finally, we demonstrate that blockade of κ-opioid receptors (500 ng nor-bni) within the nucleus accumbens (nac) shell abolishes selective aggression in both sexes, but blockade of these receptors within the nac core enhances this behavior specifically in females. |
2012-07-27 |
2023-08-12 |
Not clear |
| Dani Dumitriu, Quincey Laplant, Yael S Grossman, Caroline Dias, William G Janssen, Scott J Russo, John H Morrison, Eric J Nestle. Subregional, dendritic compartment, and spine subtype specificity in cocaine regulation of dendritic spines in the nucleus accumbens. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 32. issue 20. 2012-07-27. PMID:22593064. |
numerous studies have found that chronic cocaine increases dendritic spine density of medium spiny neurons in the nucleus accumbens (nac). |
2012-07-27 |
2023-08-12 |
mouse |
| Tünde Molnár, Arpád Dobolyi, Gabriella Nyitrai, Péter Barabás, László Héja, Zsuzsa Emri, Miklós Palkovits, Julianna Kardo. Calcium signals in the nucleus accumbens: activation of astrocytes by ATP and succinate. BMC neuroscience. vol 12. 2012-07-26. PMID:21967230. |
the purpose of the present study is to identify the characteristics of atp-evoked glial signalling in the brain reward area, the nucleus accumbens (nac), and thereby to explore the action of citric acid cycle intermediate succinate (suc). |
2012-07-26 |
2023-08-12 |
Not clear |
| Fabio Cacciapaglia, Michael P Saddoris, R Mark Wightman, Regina M Carell. Differential dopamine release dynamics in the nucleus accumbens core and shell track distinct aspects of goal-directed behavior for sucrose. Neuropharmacology. vol 62. issue 5-6. 2012-07-23. PMID:22261383. |
mesolimbic dopamine projections to the nucleus accumbens (nac) have been implicated in goal-directed behaviors for natural rewards and in learning processes involving cue-reward associations. |
2012-07-23 |
2023-08-12 |
rat |
| Shunsuke Tanahashi, Yuto Ueda, Akira Nakajima, Satoshi Yamamura, Hiroshi Nagase, Motohiro Okad. Novel δ1-receptor agonist KNT-127 increases the release of dopamine and L-glutamate in the striatum, nucleus accumbens and median pre-frontal cortex. Neuropharmacology. vol 62. issue 5-6. 2012-07-23. PMID:22266218. |
to clarify the functional selectivity of knt-127 and neurotransmission regulating system of δ1-receptor, the present study investigated the interaction between knt-127 and δ-receptor antagonists on the release of dopamine, l-glutamate and gaba in nucleus accumbens (nac), striatum and median pre-frontal cortex (mpfc) using multi-probe microdialysis. |
2012-07-23 |
2023-08-12 |
Not clear |
| Casey E O'Neill, McKenzie L LeTendre, Ryan K Bachtel. Adenosine A2A receptors in the nucleus accumbens bi-directionally alter cocaine seeking in rats. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 37. issue 5. 2012-07-20. PMID:22169945. |
adenosine a(2a) receptors are colocalized with d(2) receptors on nucleus accumbens (nac) medium spiny neurons where they antagonize d(2) receptor activity. |
2012-07-20 |
2023-08-12 |
rat |
| Darlene H Brunzell, J Michael McIntos. Alpha7 nicotinic acetylcholine receptors modulate motivation to self-administer nicotine: implications for smoking and schizophrenia. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 37. issue 5. 2012-07-20. PMID:22169946. |
before pr, rats received local infusions of 0, 10, or 20 pmol of a selective α7 nachr antagonist, α-conotoxin arib [v11l,v16d] (arib) into the nucleus accumbens (nac) shell or the anterior cingulate cortex, brain areas that contribute to motivation for drug reward. |
2012-07-20 |
2023-08-12 |
rat |
| Kevin D Lominac, Arianne D Sacramento, Karen K Szumlinski, Tod E Kippi. Distinct neurochemical adaptations within the nucleus accumbens produced by a history of self-administered vs non-contingently administered intravenous methamphetamine. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 37. issue 3. 2012-07-19. PMID:22030712. |
thus, we employed microdialysis in rats trained to self-administer intravenous (iv) infusions of methamphetamine (meth-sa) or saline (sal) and a group of rats receiving non-contingent iv infusions of methamphetamine (meth-nc) at 1 or 21 days withdrawal to determine the dopamine and glutamate responses in the nucleus accumbens (nac) to a 2 mg/kg methamphetamine intraperitoneal challenge. |
2012-07-19 |
2023-08-12 |
rat |
| Erik B Oleson, Michael V Beckert, Joshua T Morra, Carien S Lansink, Roger Cachope, Rehab A Abdullah, Amy L Loriaux, Dustin Schetters, Tommy Pattij, Mitchell F Roitman, Aron H Lichtman, Joseph F Chee. Endocannabinoids shape accumbal encoding of cue-motivated behavior via CB1 receptor activation in the ventral tegmentum. Neuron. vol 73. issue 2. 2012-07-19. PMID:22284189. |
transient increases in nucleus accumbens (nac) dopamine concentration are observed when animals are presented with motivationally salient stimuli and are theorized to energize reward seeking. |
2012-07-19 |
2023-08-12 |
Not clear |