| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yu-Chun Wang, Ue-Cheung Ho, Meng-Ching Ko, Chun-Chieh Liao, Li-Jen Le. Differential neuronal changes in medial prefrontal cortex, basolateral amygdala and nucleus accumbens after postweaning social isolation. Brain structure & function. vol 217. issue 2. 2012-09-04. PMID:22002740. |
the mesocorticolimbic system contains dopamine (da)-producing neurons in the ventral tegmental area (vta) and their projection targets, including the medial prefrontal cortex (mpfc), amygdala (amy) and nucleus accumbens (nac). |
2012-09-04 |
2023-08-12 |
rat |
| Hai-kang Zhao, Chong-wang Chang, Ning Geng, Li Gao, Jing Wang, Xin Wang, Ya-rong Wang, Xue-lian Wang, Guo-dong Ga. Associations between personality changes and nucleus accumbens ablation in opioid addicts. Acta pharmacologica Sinica. vol 33. issue 5. 2012-08-28. PMID:22504903. |
it has been reported that nucleus accumbens (nac) lesions can help to prevent relapse in opioid addicts. |
2012-08-28 |
2023-08-12 |
Not clear |
| Feng Wu, Ke-Ren Xiong, Li-Fa Wan. [Effects of electroacupuncture intervention at different time in A day on expression of tyrosine hydroxylase and C-fos in nucleus accumbens in ketamine addiction rats]. Zhen ci yan jiu = Acupuncture research. vol 37. issue 2. 2012-08-28. PMID:22764597. |
to observe the effect of electroacupuncture (ea) intervention at different time in a day on the expression of tyrosine hydroxylase (th) and c-fos in the nucleus accumbens (nac) so as to explore its mechanism underlying improvement of ketamine addiction. |
2012-08-28 |
2023-08-12 |
rat |
| Osama A Abulseoud, Joseph D Miller, Jinhua Wu, Doo-Sup Choi, Daniel P Holschneide. Ceftriaxone upregulates the glutamate transporter in medial prefrontal cortex and blocks reinstatement of methamphetamine seeking in a condition place preference paradigm. Brain research. vol 1456. 2012-08-23. PMID:22521042. |
using real time pcr, eaat₂ mrna levels in the nucleus accumbens (nac) and medial prefrontal cortex (mpfc) were quantified in response to ceftriaxone. |
2012-08-23 |
2023-08-12 |
human |
| Yonas B Keleta, Joe L Martine. Brain Circuits of Methamphetamine Place Reinforcement Learning: The Role of the Hippocampus-VTA Loop. Brain and behavior. vol 2. issue 2. 2012-08-23. PMID:22574281. |
vta is primary source of dopamine (da) to the nucleus accumbens (nac) and the ventral hippocampus (vhc). |
2012-08-23 |
2023-08-12 |
rat |
| Zhengtao Hu, Yi Deng, Chunyan Hu, Pengchi Deng, Qian Bu, Guangyan Yan, Jiaqing Zhou, Xue Shao, Jinxuan Zhao, Yan Li, Ruiming Zhu, Youzhi Xu, Yinglan Zhao, Xiaobo Ce. ¹H NMR-based metabonomic analysis of brain in rats of morphine dependence and withdrawal intervention. Behavioural brain research. vol 231. issue 1. 2012-08-20. PMID:22391120. |
in the present study, the metabolic changes in brain hippocampus, nucleus accumbens (nac), prefrontal cortex (pfc) and striatum of rats with morphine dependence and withdrawal intervention were explored by using ¹h nuclear magnetic resonance coupled with principal component analysis, partial least squares and orthogonal signal correction analysis. |
2012-08-20 |
2023-08-12 |
rat |
| Melissa L Perreault, Theresa Fan, Mohammed Alijaniaram, Brian F O'Dowd, Susan R Georg. Dopamine D1-D2 receptor heteromer in dual phenotype GABA/glutamate-coexpressing striatal medium spiny neurons: regulation of BDNF, GAD67 and VGLUT1/2. PloS one. vol 7. issue 3. 2012-08-20. PMID:22428025. |
activation of the d1r-d2r heteromer in these neurons resulted in the simultaneous, but differential regulation of proteins involved in gaba and glutamate production or vesicular uptake in the nucleus accumbens (nac), ventral tegmental area (vta), caudate putamen and substantia nigra (sn). |
2012-08-20 |
2023-08-12 |
Not clear |
| Min Li, Fu-Rong Dai, Xiao-Ping Du, Qi-Dong Yang, Xiuwu Zhang, Yuxiang Che. Infusion of BDNF into the nucleus accumbens of aged rats improves cognition and structural synaptic plasticity through PI3K-ILK-Akt signaling. Behavioural brain research. vol 231. issue 1. 2012-08-20. PMID:22446058. |
to investigate the involvement of the nucleus accumbens (nac) in cognitive impairment and the therapeutic effects of brain-derived neurotrophic factor (bdnf) in an animal model of cognitive deficit, we infused bdnf into the nac of cognitively impaired aged rats. |
2012-08-20 |
2023-08-12 |
rat |
| AliAkbar Kargari, Effat Ramshini, HojjatAllah Alaei, Mohsen Sedighi, Shahrbanoo Orya. Different current intensities electrical stimulation of prelimbic cortex of mPFC produces different effects on morphine-induced conditioned place preference in rats. Behavioural brain research. vol 231. issue 1. 2012-08-20. PMID:22465169. |
the mpfc receives strong dopaminergic innervations from ventral tegmental area (vta) that comprises a portion of the mesolimbic dopaminergic system (mlds), and in turn sends glutamate projection to both the vta and nucleus accumbens (nac). |
2012-08-20 |
2023-08-12 |
rat |
| Milene C Carvalho, Caio M Moreira, Janaína M Zanoveli, Marcus L Brandã. Central, but not basolateral, amygdala involvement in the anxiolytic-like effects of midazolam in rats in the elevated plus maze. Journal of psychopharmacology (Oxford, England). vol 26. issue 4. 2012-08-17. PMID:21148026. |
in the present study, we ethopharmacologically analyzed the behavior of rats subjected to the epm and the tissue content of the monoamines dopamine (da) and serotonin (5-ht) and their metabolites in the nucleus accumbens (nac), dorsal hippocampus (dh), and dorsal striatum (ds) of animals injected with saline or midazolam (20 and 30 nmol/0.2 µl) into the bla or cea. |
2012-08-17 |
2023-08-12 |
rat |
| Kimiko Maruyama, Rie Shimoju, Masato Ohkubo, Hitoshi Maruyama, Mieko Kurosaw. Tactile skin stimulation increases dopamine release in the nucleus accumbens in rats. The journal of physiological sciences : JPS. vol 62. issue 3. 2012-08-15. PMID:22411566. |
we investigated the effect of mild (non-noxious) tactile stimulation (stroking) of skin on dopamine (da) release in the nucleus accumbens (nac) of rats. |
2012-08-15 |
2023-08-12 |
rat |
| Weiping Tian, Mei Zhao, Min Li, Tianbao Song, Min Zhang, Li Quan, Shengbin Li, Zhong Sheng Su. Reversal of cocaine-conditioned place preference through methyl supplementation in mice: altering global DNA methylation in the prefrontal cortex. PloS one. vol 7. issue 3. 2012-08-13. PMID:22438930. |
using mice conditioned place preference (cpp) procedure, we measured global dna methylation level in the nucleus accumbens (nac) and the prefrontal cortex (pfc) associated with drug rewarding effects. |
2012-08-13 |
2023-08-12 |
mouse |
| Huifen Liu, Miaojun Lai, Xin Zhou, Huaqiang Zhu, Yu Liu, Anna Sun, Baomiao Ma, Fuqiang Zhang, Wenhua Zho. Galantamine attenuates the heroin seeking behaviors induced by cues after prolonged withdrawal in rats. Neuropharmacology. vol 62. issue 8. 2012-08-10. PMID:22342742. |
evidence shows that acetylcholinergic transmission in the ventral tegmental area (vta) or nucleus accumbens (nac) plays an important role in heroin-seeking induced by cues. |
2012-08-10 |
2023-08-12 |
rat |
| Xiaobo Wu, Meimei Shi, Chunling Wei, Minghao Yang, Yihui Liu, Zhiqiang Liu, Xia Zhang, Wei Re. Potentiation of synaptic strength and intrinsic excitability in the nucleus accumbens after 10 days of morphine withdrawal. Journal of neuroscience research. vol 90. issue 6. 2012-08-10. PMID:22388870. |
neuroadaptations in the nucleus accumbens (nac) are associated with the development of drug addiction. |
2012-08-10 |
2023-08-12 |
Not clear |
| T Enoksson, J Bertran-Gonzalez, M J Christi. Nucleus accumbens D2- and D1-receptor expressing medium spiny neurons are selectively activated by morphine withdrawal and acute morphine, respectively. Neuropharmacology. vol 62. issue 8. 2012-08-10. PMID:22410393. |
after chronic morphine, naloxone-precipitated withdrawal strongly increased expression of c-fos immunoreactivity, predominantly in d2-receptor (d2r) medium-sized spiny neurons (msns) of the nucleus accumbens (nac) core and shell regions. |
2012-08-10 |
2023-08-12 |
mouse |
| David J Hinton, Moonnoh R Lee, Taylor L Jacobson, Prasanna K Mishra, Mark A Frye, David A Mrazek, Slobodan I Macura, Doo-Sup Cho. Ethanol withdrawal-induced brain metabolites and the pharmacological effects of acamprosate in mice lacking ENT1. Neuropharmacology. vol 62. issue 8. 2012-08-10. PMID:22616110. |
to investigate the effect of acamprosate on brain metabolites in the medial prefrontal cortex (mpfc) and nucleus accumbens (nac), we employed in vivo 16.4 t proton magnetic resonance spectroscopy. |
2012-08-10 |
2023-08-12 |
mouse |
| Julie M Brooks, Martin Sarter, John P Brun. Transient inactivation of the neonatal ventral hippocampus permanently disrupts the mesolimbic regulation of prefrontal cholinergic transmission: implications for schizophrenia. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 36. issue 12. 2012-08-08. PMID:21814184. |
stimulation of nmda receptors in nucleus accumbens (nac) increases acetylcholine (ach) release in the prefrontal cortex (pfc), a mechanism recently demonstrated to contribute to the control of attentional performance. |
2012-08-08 |
2023-08-12 |
rat |
| Hanne M Hoffmann, Roser Nadal, Michel Vignes, Jordi Orti. Chronic cocaine self-administration modulates ERK1/2 and CREB responses to dopamine receptor agonists in striatal slices. Addiction biology. vol 17. issue 3. 2012-08-06. PMID:21812869. |
brains from sham controls and cocaine rats were extracted 1 day after the last session, and slices obtained from the striatum and nucleus accumbens (nac) were incubated in vitro with or without the d1r agonist skf38393 or the d2r agonist quinpirole. |
2012-08-06 |
2023-08-12 |
rat |
| Leandro F Vendruscolo, Estelle Barbier, Joel E Schlosburg, Kaushik K Misra, Timothy W Whitfield, Marian L Logrip, Catherine Rivier, Vez Repunte-Canonigo, Eric P Zorrilla, Pietro P Sanna, Markus Heilig, George F Koo. Corticosteroid-dependent plasticity mediates compulsive alcohol drinking in rats. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 32. issue 22. 2012-08-06. PMID:22649234. |
acute alcohol withdrawal was accompanied by downregulated gr mrna in various stress/reward-related brain regions [i.e., prefrontal cortex, nucleus accumbens (nac), and bed nucleus of the stria terminalis (bnst)], whereas protracted alcohol abstinence was accompanied by upregulated gr mrna in the nac core, ventral bnst, and central nucleus of the amygdala. |
2012-08-06 |
2023-08-12 |
rat |
| Vincent Vialou, Jian Feng, Alfred J Robison, Stacy M Ku, Deveroux Ferguson, Kimberly N Scobie, Michelle S Mazei-Robison, Ezekiell Mouzon, Eric J Nestle. Serum response factor and cAMP response element binding protein are both required for cocaine induction of ΔFosB. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 32. issue 22. 2012-08-06. PMID:22649236. |
here, we demonstrate a necessary role for two transcription factors, camp response element binding protein (creb) and serum response factor (srf), in mediating this induction within the mouse nucleus accumbens (nac), a key brain reward region. |
2012-08-06 |
2023-08-12 |
mouse |