| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Stephanie K Nygard, Anthony Klambatsen, Ruhal Hazim, Mohamed H Eltareb, Jeff C Blank, Anna J Chang, Vanya Quinones-Jenab, Shirzad Jena. Sexually dimorphic intracellular responses after cocaine-induced conditioned place preference expression. Brain research. vol 1520. 2014-04-11. PMID:23665060. |
in the nucleus accumbens (nac) following cpp expression, cocaine treated animals showed increased phosphorylated erk (perk), phosphorylated creb (pcreb) and Δfosb protein levels. |
2014-04-11 |
2023-08-12 |
rat |
| Martin O Job, Li L Shen, Michael J Kuha. The inhibition of cocaine-induced locomotor activity by CART 55-102 is lost after repeated cocaine administration. Neuroscience letters. vol 550. 2014-04-11. PMID:23819981. |
in this regard, it is postulated to be a homeostatic, regulatory factor on dopaminergic activity in the nucleus accumbens (nac). |
2014-04-11 |
2023-08-12 |
Not clear |
| Laura E Been, Nancy A Staffend, Avery Tucker, Robert L Meise. Vesicular glutamate transporter 2 and tyrosine hydroxylase are not co-localized in Syrian hamster nucleus accumbens afferents. Neuroscience letters. vol 550. 2014-04-11. PMID:23850605. |
the nucleus accumbens (nac) is an important brain region for motivation, reinforcement, and reward. |
2014-04-11 |
2023-08-12 |
mouse |
| Andrew F Scheyer, Marina E Wolf, Kuei Y Tsen. A protein synthesis-dependent mechanism sustains calcium-permeable AMPA receptor transmission in nucleus accumbens synapses during withdrawal from cocaine self-administration. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 34. issue 8. 2014-04-10. PMID:24553949. |
rats evaluated after ∼1 month of withdrawal from such regimens ("incubated rats") exhibit changes in medium spiny neurons (msns) of the nucleus accumbens (nac) that include accumulation of ca(2+)-permeable ampa receptors (cp-ampars) and a switch in group i metabotropic glutamate receptor (mglur)-mediated suppression of synaptic transmission from mglur5-dependent to mglur1-dependent. |
2014-04-10 |
2023-08-12 |
rat |
| Maria A De Luc. Habituation of the responsiveness of mesolimbic and mesocortical dopamine transmission to taste stimuli. Frontiers in integrative neuroscience. vol 8. 2014-04-09. PMID:24624065. |
the presentation of novel, remarkable, and unpredictable tastes increases dopamine (da) transmission in different da terminal areas such as the nucleus accumbens (nac) shell and core and the medial prefrontal cortex (mpfc), as estimated by in vivo microdialysis studies in rats. |
2014-04-09 |
2023-08-12 |
rat |
| Ainhoa Plaza-Zabala, África Flores, Elena Martín-García, Rocío Saravia, Rafael Maldonado, Fernando Berrender. A role for hypocretin/orexin receptor-1 in cue-induced reinstatement of nicotine-seeking behavior. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 38. issue 9. 2014-04-04. PMID:23518606. |
in addition, relapse to nicotine-seeking increased the phosphorylation levels of glur2-ser880, nr1-ser890, and p38 mapk in the nucleus accumbens (nac), but not in the prefrontal cortex. |
2014-04-04 |
2023-08-12 |
Not clear |
| Anthony Purgianto, Andrew F Scheyer, Jessica A Loweth, Kerstin A Ford, Kuei Y Tseng, Marina E Wol. Different adaptations in AMPA receptor transmission in the nucleus accumbens after short vs long access cocaine self-administration regimens. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 38. issue 9. 2014-04-04. PMID:23546386. |
ca(2+)-permeable ampa receptors (cp-ampars) accumulate in the nucleus accumbens (nac) after ∼1 month of withdrawal from a long-access cocaine self-administration regimen (6 h/d, 10d). |
2014-04-04 |
2023-08-12 |
rat |
| Jennifer Keller, Christina B Young, Elizabeth Kelley, Katherine Prater, Daniel J Levitin, Vinod Meno. Trait anhedonia is associated with reduced reactivity and connectivity of mesolimbic and paralimbic reward pathways. Journal of psychiatric research. vol 47. issue 10. 2014-04-04. PMID:23791396. |
we found that trait anhedonia was negatively correlated with pleasantness ratings of music stimuli and with activation of key brain structures involved in reward processing, including nucleus accumbens (nac), basal forebrain and hypothalamus which are linked by the medial forebrain bundle to the ventral tegmental area (vta). |
2014-04-04 |
2023-08-12 |
human |
| Kimberly N Scobie, Diane Damez-Werno, HaoSheng Sun, NingYi Shao, Amy Gancarz, Clarisse H Panganiban, Caroline Dias, JaWook Koo, Paola Caiafa, Lewis Kaufman, Rachael L Neve, David M Dietz, Li Shen, Eric J Nestle. Essential role of poly(ADP-ribosyl)ation in cocaine action. Proceedings of the National Academy of Sciences of the United States of America. vol 111. issue 5. 2014-04-03. PMID:24449909. |
repeated cocaine administration, including self-administration, increased global levels of parp-1 and its mark par in mouse nucleus accumbens (nac), a key brain reward region. |
2014-04-03 |
2023-08-12 |
mouse |
| Robyn Mary Brown, Shaun Yon-Seng Khoo, Andrew John Lawrenc. Central orexin (hypocretin) 2 receptor antagonism reduces ethanol self-administration, but not cue-conditioned ethanol-seeking, in ethanol-preferring rats. The international journal of neuropsychopharmacology. vol 16. issue 9. 2014-04-01. PMID:23601187. |
to determine where in the brain ox(2)r were acting to modulate ethanol self-administration, tcs-ox2-29 was microinjected into either the shell or core of the nucleus accumbens (nac). |
2014-04-01 |
2023-08-12 |
rat |
| Kaili Anier, Alexander Zharkovsky, Anti Kald. S-adenosylmethionine modifies cocaine-induced DNA methylation and increases locomotor sensitization in mice. The international journal of neuropsychopharmacology. vol 16. issue 9. 2014-04-01. PMID:23684129. |
using mouse nucleus accumbens (nac) tissue, whole-genome gene expression profiling revealed that repeated sam treatment affected a limited number of genes, but significantly modified cocaine-induced gene expression by blunting non-specifically the cocaine response. |
2014-04-01 |
2023-08-12 |
mouse |
| Kathryn M Gill, Anthony A Grac. Differential effects of acute and repeated stress on hippocampus and amygdala inputs to the nucleus accumbens shell. The international journal of neuropsychopharmacology. vol 16. issue 9. 2014-04-01. PMID:23745764. |
the basolateral amygdala (bla) and ventral subiculum (vsub) of the hippocampus convey emotion and context information, respectively, to the nucleus accumbens (nac). |
2014-04-01 |
2023-08-12 |
Not clear |
| Briac Halbout, Rick E Bernardi, Anita C Hansson, Rainer Spanage. Incubation of cocaine seeking following brief cocaine experience in mice is enhanced by mGluR1 blockade. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 34. issue 5. 2014-04-01. PMID:24478360. |
the incubation of cocaine craving describes the time-dependent augmentation of cue-induced cocaine seeking during withdrawal from prolonged cocaine self-administration and requires time-dependent changes in neuroplasticity at the level of glutamatergic synapses in the nucleus accumbens (nac). |
2014-04-01 |
2023-08-12 |
mouse |
| Petra Amchova, Jana Kucerova, Valentina Giugliano, Zuzana Babinska, Mary T Zanda, Maria Scherma, Ladislav Dusek, Paola Fadda, Vincenzo Micale, Alexandra Sulcova, Walter Fratta, Liana Fattor. Enhanced self-administration of the CB1 receptor agonist WIN55,212-2 in olfactory bulbectomized rats: evaluation of possible serotonergic and dopaminergic underlying mechanisms. Frontiers in pharmacology. vol 5. 2014-04-01. PMID:24688470. |
finally, dopamine levels in the nucleus accumbens (nac) of obx rats did not increase in response to a win challenge, as in sham rats, indicating a dopaminergic dysfunction in bulbectomized rats. |
2014-04-01 |
2023-08-12 |
rat |
| P Trifilieff, B Feng, E Urizar, V Winiger, R D Ward, K M Taylor, D Martinez, H Moore, P D Balsam, E H Simpson, J A Javitc. Increasing dopamine D2 receptor expression in the adult nucleus accumbens enhances motivation. Molecular psychiatry. vol 18. issue 9. 2014-03-25. PMID:23711983. |
as disruption of d2r signaling in the ventral striatum--including the nucleus accumbens (nac)--impairs motivation, we sought to determine whether potentiating postsynaptic d2r-dependent signaling in the nac would improve motivation. |
2014-03-25 |
2023-08-12 |
Not clear |
| Benjamin D Hobson, Casey E O'Neill, Sophia C Levis, Lisa M Monteggia, Rachael L Neve, David W Self, Ryan K Bachtel. Adenosine A1 and dopamine d1 receptor regulation of AMPA receptor phosphorylation and cocaine-seeking behavior. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 38. issue 10. 2014-03-24. PMID:23598433. |
ampar (α-amino-3-hydroxy-5-methylisoxazole-4-propionate glutamate receptor) stimulation in the nucleus accumbens (nac) is critical in cocaine seeking. |
2014-03-24 |
2023-08-12 |
Not clear |
| Robert Wickham, Wojciech Solecki, Liza Rathbun, J Michael McIntosh, Nii A Add. Ventral tegmental area α6β2 nicotinic acetylcholine receptors modulate phasic dopamine release in the nucleus accumbens core. Psychopharmacology. vol 229. issue 1. 2014-03-21. PMID:23624852. |
cholinergic and glutamatergic inputs into the ventral tegmental area (vta) are crucial for modulating burst firing activity and subsequent phasic da release in the nucleus accumbens (nac), but the specific vta nicotinic receptor subtypes that regulate phasic da release have not been identified. |
2014-03-21 |
2023-08-12 |
Not clear |
| Floor van Heesch, Jolanda Prins, Gerdien A H Korte-Bouws, Koen G C Westphal, Suzanne Lemstra, Berend Olivier, Aletta D Kraneveld, S Mechiel Kort. Systemic tumor necrosis factor-alpha decreases brain stimulation reward and increases metabolites of serotonin and dopamine in the nucleus accumbens of mice. Behavioural brain research. vol 253. 2014-03-18. PMID:23896053. |
the effect of an intraperitoneal tnf-α injection on extracellular monoamine and metabolite concentrations was investigated by in vivo microdialysis in the nucleus accumbens (nac) of c57bl/6 mice. |
2014-03-18 |
2023-08-12 |
mouse |
| Li-Li Sun, Yan Zhang, Jian-feng Liu, Jun Wang, Wei-li Zhu, Li-yan Zhao, Yan-xue Xue, Lin Lu, Jie Sh. Role of melanin-concentrating hormone in the nucleus accumbens shell in rats behaviourally sensitized to methamphetamine. The international journal of neuropsychopharmacology. vol 16. issue 8. 2014-03-14. PMID:23449013. |
the present study investigated the role of mch in the nucleus accumbens (nac) in rats behaviourally sensitized to methamphetamine (meth). |
2014-03-14 |
2023-08-12 |
rat |
| Edward P Maguire, Tom Macpherson, Jerome D Swinny, Claire I Dixon, Murray B Herd, Delia Belelli, David N Stephens, Sarah L King, Jeremy J Lamber. Tonic inhibition of accumbal spiny neurons by extrasynaptic α4βδ GABAA receptors modulates the actions of psychostimulants. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 34. issue 3. 2014-03-13. PMID:24431441. |
within the nucleus accumbens (nac), synaptic gabaa receptors (gabaars) mediate phasic inhibition of medium spiny neurons (msns) and influence behavioral responses to cocaine. |
2014-03-13 |
2023-08-12 |
mouse |