| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Daniela Cassataro, Daniella Bergfeldt, Cariz Malekian, Jared X Van Snellenberg, Panayotis K Thanos, Gord Fishell, Lucas Sjulso. Reverse pharmacogenetic modulation of the nucleus accumbens reduces ethanol consumption in a limited access paradigm. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 39. issue 2. 2014-08-21. PMID:23903031. |
bilateral stereotactic lesioning of the nucleus accumbens (nac) core reduces relapse rates in alcohol-dependent patients but may cause irreversible cognitive deficits. |
2014-08-21 |
2023-08-12 |
mouse |
| Neal R Swerdlow, Susan B Powell, Michelle R Breier, Samantha R Hines, Gregory A Ligh. Coupling of gene expression in medial prefrontal cortex and nucleus accumbens after neonatal ventral hippocampal lesions accompanies deficits in sensorimotor gating and auditory processing in rats. Neuropharmacology. vol 75. 2014-08-19. PMID:23810830. |
in intact rats, the regulation of ppi by the ventral hippocampus (vh) is mediated via interactions with medial prefrontal cortex (mpfc) and nucleus accumbens (nac). |
2014-08-19 |
2023-08-12 |
rat |
| Wojciech Solecki, Robert J Wickham, Shay Behrens, Jie Wang, Blake Zwerling, Graeme F Mason, Nii A Add. Differential role of ventral tegmental area acetylcholine and N-methyl-D-aspartate receptors in cocaine-seeking. Neuropharmacology. vol 75. 2014-08-19. PMID:23850572. |
cues evoke burst firing of ventral tegmental area (vta) dopamine (da) neurons and phasic da release in the nucleus accumbens (nac). |
2014-08-19 |
2023-08-12 |
human |
| Morris D Faiman, Swetha Kaul, Shaheen A Latif, Todd D Williams, Craig E Lunt. S-(N, N-diethylcarbamoyl)glutathione (carbamathione), a disulfiram metabolite and its effect on nucleus accumbens and prefrontal cortex dopamine, GABA, and glutamate: a microdialysis study. Neuropharmacology. vol 75. 2014-08-19. PMID:23891816. |
in the present studies, we employed microdialysis techniques to investigate the effect of carb administration on dopamine (da), gaba, and glutamate (glu) in the nucleus accumbens (nac) and medial prefrontal cortex (mpfc), two brain regions implicated in substance abuse dependence. |
2014-08-19 |
2023-08-12 |
rat |
| Wei-Lun Sun, Nortorious T Coleman, Agnieszka Zelek-Molik, Sarah M Barry, Timothy W Whitfield, Jacqueline F McGint. Relapse to cocaine-seeking after abstinence is regulated by cAMP-dependent protein kinase A in the prefrontal cortex. Addiction biology. vol 19. issue 1. 2014-08-18. PMID:23461423. |
abstinence from cocaine self-administration (sa) is associated with neuroadaptations in the prefrontal cortex (pfc) and nucleus accumbens (nac) that are implicated in cocaine-induced neuronal plasticity and relapse to drug-seeking. |
2014-08-18 |
2023-08-12 |
Not clear |
| Ainhoa Plaza-Zabala, Xuan Li, Mike Milovanovic, Jessica A Loweth, Rafael Maldonado, Fernando Berrendero, Marina E Wol. An investigation of interactions between hypocretin/orexin signaling and glutamate receptor surface expression in the rat nucleus accumbens under basal conditions and after cocaine exposure. Neuroscience letters. vol 557 Pt B. 2014-08-18. PMID:24262606. |
however, little is known about their role in cocaine-induced synaptic plasticity in the nucleus accumbens (nac). |
2014-08-18 |
2023-08-12 |
rat |
| Jing Yuan Ma, Shan Zhi Gu, Min Meng, Yong Hui Dang, Chong Ya Huang, Emmanuel S Onaiv. Regional expression of extracellular signal-regulated kinase 1 and 2 mRNA in a morphine-induced conditioned place preference model. Brain research. vol 1543. 2014-08-18. PMID:24296091. |
in the present study, we investigated the expression of erk messenger ribonucleic acid (mrna) of the prefrontal cortex (pfc), nucleus accumbens (nac), hippocampus, and caudate putamen (cpu) in morphine-induced conditioned place preference (cpp) by real-time reverse transcriptase polymerase chain reaction (real-time pcr). |
2014-08-18 |
2023-08-12 |
Not clear |
| Aya Matsui, Brooke C Jarvie, Brooks G Robinson, Shane T Hentges, John T William. Separate GABA afferents to dopamine neurons mediate acute action of opioids, development of tolerance, and expression of withdrawal. Neuron. vol 82. issue 6. 2014-08-12. PMID:24857021. |
gaba release from interneurons in vta, projections from the nucleus accumbens (nac), and rostromedial tegmental nucleus (rmtg) was selectively activated in rat brain slices. |
2014-08-12 |
2023-08-13 |
rat |
| Kirsty Danielson, Fraser Putt, Penelope Truman, Bronwyn M Kivel. The effects of nicotine and tobacco particulate matter on dopamine uptake in the rat brain. Synapse (New York, N.Y.). vol 68. issue 2. 2014-08-11. PMID:23999947. |
nicotine (0.35 mg/kg) significantly decreased dat function in the nucleus accumbens (nac) at 30 min with no change in protein expression. |
2014-08-11 |
2023-08-12 |
rat |
| Eric J Nunes, Patrick A Randall, Samantha Podurgiel, Mercè Correa, John D Salamon. Nucleus accumbens neurotransmission and effort-related choice behavior in food motivation: effects of drugs acting on dopamine, adenosine, and muscarinic acetylcholine receptors. Neuroscience and biobehavioral reviews. vol 37. issue 9 Pt A. 2014-08-07. PMID:23583616. |
although nucleus accumbens (nac) da depletions or antagonism leave aspects of appetite and primary food motivation intact, rats with impaired da transmission reallocate their instrumental behavior away from food-reinforced tasks with high response requirements, and instead select less effortful food-seeking behaviors. |
2014-08-07 |
2023-08-12 |
rat |
| Sean P Farris, Michael F Mile. Fyn-dependent gene networks in acute ethanol sensitivity. PloS one. vol 8. issue 11. 2014-08-05. PMID:24312422. |
we characterized basal and acute ethanol-evoked (3 g/kg) gene expression patterns in nucleus accumbens (nac), prefrontal cortex (pfc), and ventral midbrain (vmb) of control and fyn knockout mice. |
2014-08-05 |
2023-08-12 |
mouse |
| Amelie Simonnet, Martine Cador, Stephanie Caill. Nicotine reinforcement is reduced by cannabinoid CB1 receptor blockade in the ventral tegmental area. Addiction biology. vol 18. issue 6. 2014-08-04. PMID:22784230. |
in the present study, we sought to determine whether central injections of a cb1 receptor antagonist delivered either into the ventral tegmental area (vta) or the nucleus accumbens (nac) may alter nicotine intravenous self-administration (ivsa). |
2014-08-04 |
2023-08-12 |
rat |
| Marcello D'Ascenzo, Maria Vittoria Podda, Claudio Grass. The role of D-serine as co-agonist of NMDA receptors in the nucleus accumbens: relevance to cocaine addiction. Frontiers in synaptic neuroscience. vol 6. 2014-07-31. PMID:25076900. |
this system, formed in part by the ventral tegmental area and nucleus accumbens (nac), has a central role in the development and expression of addictive behaviors. |
2014-07-31 |
2023-08-13 |
Not clear |
| Regina M Carelli, Elizabeth A Wes. When a good taste turns bad: Neural mechanisms underlying the emergence of negative affect and associated natural reward devaluation by cocaine. Neuropharmacology. vol 76 Pt B. 2014-07-29. PMID:23639430. |
electrophysiology studies show that this shift in palatability corresponds to an alteration in nucleus accumbens (nac) cell firing; neurons that previously responded with inhibition during infusion of the palatable sweet shifted to excitatory activity during infusion of the cocaine-devalued tastant. |
2014-07-29 |
2023-08-12 |
rat |
| Cassandra D Gipson, Yonatan M Kupchik, Peter W Kaliva. Rapid, transient synaptic plasticity in addiction. Neuropharmacology. vol 76 Pt B. 2014-07-29. PMID:23639436. |
the nucleus accumbens (nac), which integrates cortical information and regulates goal-directed behavior, undergoes long-term morphological and electrophysiological changes that may underlie the increased susceptibility for relapse in drug-experienced individuals even after long periods of withdrawal. |
2014-07-29 |
2023-08-12 |
Not clear |
| Jessica A Loweth, Kuei Y Tseng, Marina E Wol. Adaptations in AMPA receptor transmission in the nucleus accumbens contributing to incubation of cocaine craving. Neuropharmacology. vol 76 Pt B. 2014-07-29. PMID:23727437. |
here we will focus on neuroadaptations in the nucleus accumbens (nac), a region of convergence for pathways that control cocaine seeking. |
2014-07-29 |
2023-08-12 |
human |
| Chris Baeken, Daniele Marinazzo, Stephan Claes, Guo-Rong Wu, Peter Van Schuerbeek, Johan De Mey, Robert Luypaert, Rudi De Raed. COMT Val(158)Met genotypes differentially influence subgenual cingulate functional connectivity in healthy females. Frontiers in human neuroscience. vol 8. 2014-07-29. PMID:25071511. |
compared to met(158) homozygotes, val(158) allele carriers displayed significantly stronger rsfc between the sgacc and the left parahippocampal gyrus, ventromedial parts of the inferior frontal gyrus (ifg), and the nucleus accumbens (nac). |
2014-07-29 |
2023-08-13 |
Not clear |
| Kiwamu Matsuoka, Fumihiko Yasuno, Makoto Inoue, Akihide Yamamoto, Takashi Kudo, Soichiro Kitamura, Koji Okada, Kuniaki Kiuchi, Jun Kosaka, Hidehiro Iida, Toshifumi Kishimot. Microstructural changes of the nucleus accumbens due to increase of estradiol level during menstrual cycle contribute to recurrent manic episodes--a single case study. Psychiatry research. vol 221. issue 2. 2014-07-28. PMID:24345761. |
dti results showed that the patient had increased fractional anisotropy values at manic state in the bilateral nucleus accumbens (nac) and its connected areas, which is a major projection field of the mesolimbic dopamine (da) system, perhaps reflecting microstructural changes due to neuronal activation related to manic episodes. |
2014-07-28 |
2023-08-12 |
Not clear |
| Michelle L Tomaszycki, Kelsey E Aulerich, Scott E Bowe. Repeated toluene exposure increases c-Fos in catecholaminergic cells of the nucleus accumbens shell. Neurotoxicology and teratology. vol 40. 2014-07-24. PMID:24036183. |
previous studies have suggested that toluene acts like other drugs of abuse, specifically on the dopaminergic system in the nucleus accumbens (nac) and ventral tegmental area (vta) of the mesolimbic pathway. |
2014-07-24 |
2023-08-12 |
Not clear |
| Shin-ichi Adachi, Yuki Endo, Takafumi Mizushige, Satoshi Tsuzuki, Shigenobu Matsumura, Kazuo Inoue, Tohru Fushik. Increased levels of extracellular dopamine in the nucleus accumbens and amygdala of rats by ingesting a low concentration of a long-chain Fatty Acid. Bioscience, biotechnology, and biochemistry. vol 77. issue 11. 2014-07-17. PMID:24200795. |
changes in the extracellular concentration of dopamine (da) in the nucleus accumbens (nac) shell and the basolateral amygdala (bla) resulting from the voluntary ingestion of either corn oil, mineral oil, or 1% linoleic acid diluted with mineral oil as a vehicle were measured in rats by using in vivo microdialysis after they had been trained to establish a preference for corn oil. |
2014-07-17 |
2023-08-12 |
rat |