| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| ZhenHua Ren, Yu Zhan. Cells therapy for Parkinson's disease--so close and so far away. Science in China. Series C, Life sciences. vol 52. issue 7. 2009-11-05. PMID:19641865. |
potential sources for cells range from autologous grafts of dopamine secreting cells, fetal ventral mesencephalon tissue, to various stem cell types. |
2009-11-05 |
2023-08-12 |
human |
| Lachlan H Thompson, Anders Björklun. Transgenic reporter mice as tools for studies of transplantability and connectivity of dopamine neuron precursors in fetal tissue grafts. Progress in brain research. vol 175. 2009-10-27. PMID:19660649. |
cell therapy for parkinson's disease (pd) is based on the idea that new midbrain dopamine (mda) neurons, implanted directly into the brain of the patient, can structurally and functionally replace those lost to the disease. |
2009-10-27 |
2023-08-12 |
mouse |
| Heli Tuppurainen, Jyrki T Kuikka, Heimo Viinamäki, Minna Husso, Jari Tiihone. Dopamine D2/3 receptor binding potential and occupancy in midbrain and temporal cortex by haloperidol, olanzapine and clozapine. Psychiatry and clinical neurosciences. vol 63. issue 4. 2009-10-13. PMID:19496999. |
dopamine d2/3 receptor binding potential and occupancy in midbrain and temporal cortex by haloperidol, olanzapine and clozapine. |
2009-10-13 |
2023-08-12 |
Not clear |
| Heli Tuppurainen, Jyrki T Kuikka, Heimo Viinamäki, Minna Husso, Jari Tiihone. Dopamine D2/3 receptor binding potential and occupancy in midbrain and temporal cortex by haloperidol, olanzapine and clozapine. Psychiatry and clinical neurosciences. vol 63. issue 4. 2009-10-13. PMID:19496999. |
the aim of the present study was therefore to investigate dopamine d(2/3) receptor apparent binding potential (bp(app)) and occupancy in midbrain and temporal cortex among clozapine-, olanzapine- and haloperidol-treated schizophrenia patients. |
2009-10-13 |
2023-08-12 |
Not clear |
| Mianzhi Tang, Yasunori Miyamoto, Eric J Huan. Multiple roles of beta-catenin in controlling the neurogenic niche for midbrain dopamine neurons. Development (Cambridge, England). vol 136. issue 12. 2009-10-05. PMID:19439492. |
multiple roles of beta-catenin in controlling the neurogenic niche for midbrain dopamine neurons. |
2009-10-05 |
2023-08-12 |
Not clear |
| Marie E Jönsson, Yuichi Ono, Anders Björklund, Lachlan H Thompso. Identification of transplantable dopamine neuron precursors at different stages of midbrain neurogenesis. Experimental neurology. vol 219. issue 1. 2009-09-25. PMID:19555687. |
identification of transplantable dopamine neuron precursors at different stages of midbrain neurogenesis. |
2009-09-25 |
2023-08-12 |
mouse |
| Andon N Placzek, Tao A Zhang, John A Dan. Age dependent nicotinic influences over dopamine neuron synaptic plasticity. Biochemical pharmacology. vol 78. issue 7. 2009-09-21. PMID:19464268. |
the dopamine (da) system of the ventral midbrain plays a critical role as mammals learn adaptive behaviors driven by environmental salience and reward. |
2009-09-21 |
2023-08-12 |
Not clear |
| Andon N Placzek, Tao A Zhang, John A Dan. Age dependent nicotinic influences over dopamine neuron synaptic plasticity. Biochemical pharmacology. vol 78. issue 7. 2009-09-21. PMID:19464268. |
one aspect of that sensitivity is drug-induced synaptic plasticity at excitatory synapses onto the dopamine neurons in the ventral midbrain. |
2009-09-21 |
2023-08-12 |
Not clear |
| Phil D Livingstone, Susan Wonnacot. Nicotinic acetylcholine receptors and the ascending dopamine pathways. Biochemical pharmacology. vol 78. issue 7. 2009-09-21. PMID:19523928. |
nicotinic acetylcholine receptors (nachrs) are widely expressed in midbrain dopamine neurons that project to dorsal striatum, nucleus accumbens and prefrontal cortex. |
2009-09-21 |
2023-08-12 |
Not clear |
| Simon Sydserff, E J Sutton, Dekun Song, Michael C Quirk, Carla Maciag, Chaoying Li, Gerald Jonak, David Gurley, John C Gordon, Edward P Christian, James J Doherty, Tom Hudzik, Edwin Johnson, Ladislav Mrzljak, Tim Piser, Gennady N Smagin, Yi Wang, Dan Widzowski, Jeffrey S Smit. Selective alpha7 nicotinic receptor activation by AZD0328 enhances cortical dopamine release and improves learning and attentional processes. Biochemical pharmacology. vol 78. issue 7. 2009-09-21. PMID:19615981. |
azd0328, a novel spirofuropyridine neuronal nicotinic receptor partial agonist, was used to investigate the role of alpha7 neuronal nicotinic receptor (nnr) activation in the modulation of midbrain dopamine neuron function, cortical dopamine release and on two behavioral tasks known to be dependent on optimal levels of cortical dopamine. |
2009-09-21 |
2023-08-12 |
mouse |
| Simon Sydserff, E J Sutton, Dekun Song, Michael C Quirk, Carla Maciag, Chaoying Li, Gerald Jonak, David Gurley, John C Gordon, Edward P Christian, James J Doherty, Tom Hudzik, Edwin Johnson, Ladislav Mrzljak, Tim Piser, Gennady N Smagin, Yi Wang, Dan Widzowski, Jeffrey S Smit. Selective alpha7 nicotinic receptor activation by AZD0328 enhances cortical dopamine release and improves learning and attentional processes. Biochemical pharmacology. vol 78. issue 7. 2009-09-21. PMID:19615981. |
together, these data indicate that selective interaction with alpha7 nnrs by azd0328 selectively enhances midbrain dopaminergic neuronal activity causing an enhancement of cortical dopamine levels; these neurochemical changes likely, underlie the positive behavioral responses observed in two different animal models. |
2009-09-21 |
2023-08-12 |
mouse |
| Karley Y Little, Eric Ramssen, Ryan Welchko, Vitaly Volberg, Courtney J Roland, Bader Cassi. Decreased brain dopamine cell numbers in human cocaine users. Psychiatry research. vol 168. issue 3. 2009-09-17. PMID:19233481. |
cocaine use diminishes striatal and midbrain dopamine neuronal components in both post-mortem and in vivo human experiments. |
2009-09-17 |
2023-08-12 |
human |
| Karley Y Little, Eric Ramssen, Ryan Welchko, Vitaly Volberg, Courtney J Roland, Bader Cassi. Decreased brain dopamine cell numbers in human cocaine users. Psychiatry research. vol 168. issue 3. 2009-09-17. PMID:19233481. |
the present experiment involved counting midbrain dopamine neurons utilizing both melanin and tyrosine hydroxylase immunoreactivity. |
2009-09-17 |
2023-08-12 |
human |
| Karley Y Little, Eric Ramssen, Ryan Welchko, Vitaly Volberg, Courtney J Roland, Bader Cassi. Decreased brain dopamine cell numbers in human cocaine users. Psychiatry research. vol 168. issue 3. 2009-09-17. PMID:19233481. |
the estimated total number of melanized dopamine cells in the anterior midbrain was significantly reduced in cocaine users by 16%. |
2009-09-17 |
2023-08-12 |
human |
| Shelly Arreguin, Paul Nelson, Shelby Padway, Matthew Shirazi, Cortlandt Pierpon. Dopamine complexes of iron in the etiology and pathogenesis of Parkinson's disease. Journal of inorganic biochemistry. vol 103. issue 1. 2009-09-09. PMID:18976814. |
much of the neuronal damage takes place in the substantia nigra, a small region of the midbrain that contains the cell bodies of neurons that produce dopamine. |
2009-09-09 |
2023-08-12 |
Not clear |
| Filip Simunovic, Ming Yi, Yulei Wang, Laurel Macey, Lauren T Brown, Anna M Krichevsky, Susan L Andersen, Robert M Stephens, Francine M Benes, Kai C Sonnta. Gene expression profiling of substantia nigra dopamine neurons: further insights into Parkinson's disease pathology. Brain : a journal of neurology. vol 132. issue Pt 7. 2009-09-09. PMID:19052140. |
parkinson's disease is caused by a progressive loss of the midbrain dopamine (da) neurons in the substantia nigra pars compacta. |
2009-09-09 |
2023-08-12 |
human |
| Michael J Beckstead, Stephanie C Gantz, Christopher P Ford, Mary P Stenzel-Poore, Paul Em Phillips, Gregory P Mark, John T William. CRF enhancement of GIRK channel-mediated transmission in dopamine neurons. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 34. issue 8. 2009-09-02. PMID:19279570. |
dopamine neurons in the ventral midbrain contribute to learning and memory of natural and drug-related rewards. |
2009-09-02 |
2023-08-12 |
Not clear |
| Lin Lu, Xi Wang, Ping Wu, Chunmei Xu, Mei Zhao, Marisela Morales, Brandon K Harvey, Barry J Hoffer, Yavin Shaha. Role of ventral tegmental area glial cell line-derived neurotrophic factor in incubation of cocaine craving. Biological psychiatry. vol 66. issue 2. 2009-09-02. PMID:19345340. |
here, we studied the role of glial cell line-derived neurotrophic factor (gdnf) in incubation of cocaine craving because, like bdnf, gdnf provides trophic support to midbrain dopamine neurons. |
2009-09-02 |
2023-08-12 |
Not clear |
| Vincent Ries, Hsiao-Chun Cheng, Amy Baohan, Tatyana Kareva, Tinmarla F Oo, Margarita Rzhetskaya, Ross J Bland, Matthew J During, Nikolai Kholodilov, Robert E Burk. Regulation of the postnatal development of dopamine neurons of the substantia nigra in vivo by Akt/protein kinase B. Journal of neurochemistry. vol 110. issue 1. 2009-08-21. PMID:19490361. |
following mitosis, specification and migration during embryogenesis, dopamine neurons of the mesencephalon undergo a postnatal naturally occurring cell death event that determines their final adult number, and a period of axonal growth that determines pattern and extent of target contacts. |
2009-08-21 |
2023-08-12 |
Not clear |
| Huifang Ji, Charlotte Hougaard, Kjartan Frisch Herrik, Dorte Strøbaek, Palle Christophersen, Paul D Shepar. Tuning the excitability of midbrain dopamine neurons by modulating the Ca2+ sensitivity of SK channels. The European journal of neuroscience. vol 29. issue 9. 2009-08-20. PMID:19473240. |
tuning the excitability of midbrain dopamine neurons by modulating the ca2+ sensitivity of sk channels. |
2009-08-20 |
2023-08-12 |
human |