| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Banafsheh Kadkhodaei, Takehito Ito, Eliza Joodmardi, Bengt Mattsson, Claude Rouillard, Manolo Carta, Shin-ichi Muramatsu, Chiho Sumi-Ichinose, Takahide Nomura, Daniel Metzger, Pierre Chambon, Eva Lindqvist, Nils-Göran Larsson, Lars Olson, Anders Björklund, Hiroshi Ichinose, Thomas Perlman. Nurr1 is required for maintenance of maturing and adult midbrain dopamine neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 29. issue 50. 2010-01-26. PMID:20016108. |
nurr1, one such transcription factor, is essential for early differentiation of midbrain dopamine (mda) neurons but continues to be expressed into adulthood. |
2010-01-26 |
2023-08-12 |
mouse |
| Howard J Federof. Nur(R1)turing a notion on the etiopathogenesis of Parkinson's disease. Neurotoxicity research. vol 16. issue 3. 2010-01-25. PMID:19526279. |
encoding an orphan transcription factor that is expressed at high levels within discrete regions of the developing and adult mammalian brain, nurr1 is essential for the formation of ventral midbrain dopamine neurons. |
2010-01-25 |
2023-08-12 |
Not clear |
| Walter Francesconi, Fulvia Berton, George F Koob, Pietro Paolo Sann. Intrinsic neuronal plasticity in the juxtacapsular nucleus of the bed nuclei of the stria terminalis (jcBNST). Progress in neuro-psychopharmacology & biological psychiatry. vol 33. issue 8. 2010-01-25. PMID:19683025. |
the juxtacapsular nucleus of the anterior division of the bnst (jcbnst) receives robust glutamatergic projections from the basolateral nucleus of the amygdala (bla), the postpiriform transition area, and the insular cortex as well as dopamine (da) inputs from the midbrain. |
2010-01-25 |
2023-08-12 |
rat |
| Dardo Tomasi, Gene-Jack Wang, Ruiliang Wang, Walter Backus, Allan Geliebter, Frank Telang, Millar C Jayne, Christopher Wong, Joanna S Fowler, Nora D Volko. Association of body mass and brain activation during gastric distention: implications for obesity. PloS one. vol 4. issue 8. 2010-01-19. PMID:19718256. |
since obese subjects have dopaminergic deficits that correlate negatively with bmi and the amygdala is innervated by dopamine neurons, we hypothesized that bmi would correlate negatively with activation not just in the amygdala but also in other dopaminergic brain regions (midbrain and hypothalamus). |
2010-01-19 |
2023-08-12 |
human |
| Francesco Roselli, Nicola M Pisciotta, Robert Perneczky, Michele Pennelli, Maria S Aniello, Maria F De Caro, Ermanno Ferrannini, Bruno Tartaglione, Giovanni Defazio, Giuseppe Rubini, Paolo Livre. Severity of neuropsychiatric symptoms and dopamine transporter levels in dementia with Lewy bodies: a 123I-FP-CIT SPECT study. Movement disorders : official journal of the Movement Disorder Society. vol 24. issue 14. 2010-01-12. PMID:19705471. |
dopamine transporter (dat) imaging with (123)i-labeled ligand n-delta-(fluoropropyl)-2 beta-carbomethoxy-3beta-(4-iodophenyl)tropene ((123)i-fp-cit), which reliably measures midbrain dopaminergic dysfunction, has provided important evidence on the neurobiological substrate of some of these symptoms including apathy and depression. |
2010-01-12 |
2023-08-12 |
Not clear |
| Jerylin O Gan, Mark E Walton, Paul E M Phillip. Dissociable cost and benefit encoding of future rewards by mesolimbic dopamine. Nature neuroscience. vol 13. issue 1. 2010-01-08. PMID:19904261. |
reward-predicting cues evoke activity in midbrain dopamine neurons that encodes fundamental attributes of economic value, including reward magnitude, delay and uncertainty. |
2010-01-08 |
2023-08-12 |
rat |
| Masanori Ookubo, Hironori Yokoyama, Hiroyuki Kato, Tsutomu Arak. Gender differences on MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) neurotoxicity in C57BL/6 mice. Molecular and cellular endocrinology. vol 311. issue 1-2. 2010-01-06. PMID:19631714. |
in the present study, we investigated the time-dependent alterations of dopamine and its metabolites, striatal tyrosine hydroxylase (th) protein, dopamine transporter (dat) protein, glial fibrillary acidic protein (gfap) protein and midbrain th protein and motor function in male and female mice 5h and 1, 3 and 7 days after four administrations of mptp (20mg/kg) at 2-h intervals. |
2010-01-06 |
2023-08-12 |
mouse |
| Milan Joksimovic, Angela Anderegg, Anil Roy, Laura Campochiaro, Beth Yun, Raja Kittappa, Ronald McKay, Rajeshwar Awatraman. Spatiotemporally separable Shh domains in the midbrain define distinct dopaminergic progenitor pools. Proceedings of the National Academy of Sciences of the United States of America. vol 106. issue 45. 2010-01-06. PMID:19850875. |
midbrain dopamine neurons (mda) are important regulators of diverse physiological functions, including movement, attention, and reward behaviors. |
2010-01-06 |
2023-08-12 |
Not clear |
| Zhiguo Xie, Xiaoxi Zhuang, Linan Che. DJ-1 mRNA anatomical localization and cell type identification in the mouse brain. Neuroscience letters. vol 465. issue 3. 2010-01-04. PMID:19766170. |
in particular, all dopamine neurons in the ventral midbrain expressed dj-1 mrna. |
2010-01-04 |
2023-08-12 |
mouse |
| Kunio Kitahama, Keiko Ikemoto, Anne Jouvet, Silvia Araneda, Ikuko Nagatsu, Brigitte Raynaud, Akiyoshi Nishimura, Katsuji Nishi, Shin-Ichi Niw. Aromatic L-amino acid decarboxylase-immunoreactive structures in human midbrain, pons, and medulla. Journal of chemical neuroanatomy. vol 38. issue 2. 2009-12-22. PMID:19589383. |
the objective of the present study was to determine with precision the localization of neurons and fibers immunoreactive (ir) for aromatic l-amino acid decarboxylase (aadc), the second-step enzyme responsible for conversion of l-dihydroxyphenylalanine (l-dopa) to dopamine (da) and 5-hydroxytryptophan (5-htp) to serotonin (5-hydroxytryptamine: 5-ht) in the midbrain, pons, and medulla oblongata of the adult human brain. |
2009-12-22 |
2023-08-12 |
human |
| C Warren Olanow, Jeffrey H Kordower, Anthony E Lang, Jose A Obes. Dopaminergic transplantation for Parkinson's disease: current status and future prospects. Annals of neurology. vol 66. issue 5. 2009-12-21. PMID:19938101. |
however, all double-blind, sham-controlled, studies have failed to meet their primary endpoints, and transplantation of dopamine cells derived from the fetal mesencephalon is associated with a potentially disabling form of dyskinesia that persists even after withdrawal of levodopa (off-medication dyskinesia). |
2009-12-21 |
2023-08-12 |
Not clear |
| J W Dickerson, A M Hemmerle, S Numan, K H Lundgren, K B Seroog. Decreased expression of ErbB4 and tyrosine hydroxylase mRNA and protein in the ventral midbrain of aged rats. Neuroscience. vol 163. issue 1. 2009-12-15. PMID:19505538. |
the functional nrg receptor erbb4 is expressed by virtually all midbrain dopamine neurons. |
2009-12-15 |
2023-08-12 |
rat |
| A-Young Jo, Mi-Young Kim, Hyun-Seob Lee, Yong-Hee Rhee, Jeong-Eun Lee, Kwang-Hyun Baek, Chang-Hwan Park, Hyun-Chul Koh, Incheol Shin, Yong-Sung Lee, Sang-Hun Le. Generation of dopamine neurons with improved cell survival and phenotype maintenance using a degradation-resistant nurr1 mutant. Stem cells (Dayton, Ohio). vol 27. issue 9. 2009-12-11. PMID:19522012. |
nurr1 is a transcription factor specific for the development and maintenance of the midbrain dopamine (da) neurons. |
2009-12-11 |
2023-08-12 |
Not clear |
| Dong-Youn Hwang, Sunghoi Hong, Joo-Won Jeong, Sangdun Choi, Hansoo Kim, Jangwoo Kim, Kwang-Soo Ki. Vesicular monoamine transporter 2 and dopamine transporter are molecular targets of Pitx3 in the ventral midbrain dopamine neurons. Journal of neurochemistry. vol 111. issue 5. 2009-12-11. PMID:19780901. |
vesicular monoamine transporter 2 and dopamine transporter are molecular targets of pitx3 in the ventral midbrain dopamine neurons. |
2009-12-11 |
2023-08-12 |
mouse |
| Dong-Youn Hwang, Sunghoi Hong, Joo-Won Jeong, Sangdun Choi, Hansoo Kim, Jangwoo Kim, Kwang-Soo Ki. Vesicular monoamine transporter 2 and dopamine transporter are molecular targets of Pitx3 in the ventral midbrain dopamine neurons. Journal of neurochemistry. vol 111. issue 5. 2009-12-11. PMID:19780901. |
midbrain dopamine (mda) neurons play critical roles in the regulation of voluntary movement and their dysfunction is associated with parkinson's disease. |
2009-12-11 |
2023-08-12 |
mouse |
| Josephine B Hebsgaard, Jenny Nelander, Hanna Sabelström, Marie E Jönsson, Simon Stott, Malin Parma. Dopamine neuron precursors within the developing human mesencephalon show radial glial characteristics. Glia. vol 57. issue 15. 2009-12-09. PMID:19330857. |
dopamine neuron precursors within the developing human mesencephalon show radial glial characteristics. |
2009-12-09 |
2023-08-12 |
human |
| Afsaneh Gaillard, Mickael Decressac, Isabelle Frappé, Pierre Olivier Fernagut, Laetitia Prestoz, Stephan Besnard, Mohamed Jabe. Anatomical and functional reconstruction of the nigrostriatal pathway by intranigral transplants. Neurobiology of disease. vol 35. issue 3. 2009-12-03. PMID:19616502. |
grafted cells integrated within the host mesencephalon and expressed the dopaminergic markers tyrosine hydroxylase, vesicular monoamine transporter 2 and dopamine transporter. |
2009-12-03 |
2023-08-12 |
mouse |
| Susannah J Tye, Anthony D Miller, Charles D Blah. Differential corticosteroid receptor regulation of mesoaccumbens dopamine efflux during the peak and nadir of the circadian rhythm: a molecular equilibrium in the midbrain? Synapse (New York, N.Y.). vol 63. issue 11. 2009-11-17. PMID:19598178. |
differential corticosteroid receptor regulation of mesoaccumbens dopamine efflux during the peak and nadir of the circadian rhythm: a molecular equilibrium in the midbrain? |
2009-11-17 |
2023-08-12 |
rat |
| Christopher P Ford, Paul E M Phillips, John T William. The time course of dopamine transmission in the ventral tegmental area. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 29. issue 42. 2009-11-06. PMID:19846722. |
to determine the extent over which dopamine signals in the midbrain, the present study examined the concentration and time course of dopamine that underlies a d(2)-receptor ipsc (d(2)-ipsc) in the ventral tegmental area. |
2009-11-06 |
2023-08-12 |
Not clear |
| Christopher P Ford, Paul E M Phillips, John T William. The time course of dopamine transmission in the ventral tegmental area. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 29. issue 42. 2009-11-06. PMID:19846722. |
thus, dopamine transmission in the midbrain is more localized then previously proposed. |
2009-11-06 |
2023-08-12 |
Not clear |