| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| T D Purves-Tyson, S J Owens, D A Rothmond, G M Halliday, K L Double, J Stevens, T McCrossin, C Shannon Weicker. Putative presynaptic dopamine dysregulation in schizophrenia is supported by molecular evidence from post-mortem human midbrain. Translational psychiatry. vol 7. issue 1. 2017-11-16. PMID:28094812. |
th and the synaptic dopamine transporter (dat) proteins were examined in post-mortem midbrain (26 antipsychotic-treated schizophrenia cases per 27 controls) using immunoblotting. |
2017-11-16 |
2023-08-13 |
human |
| T D Purves-Tyson, S J Owens, D A Rothmond, G M Halliday, K L Double, J Stevens, T McCrossin, C Shannon Weicker. Putative presynaptic dopamine dysregulation in schizophrenia is supported by molecular evidence from post-mortem human midbrain. Translational psychiatry. vol 7. issue 1. 2017-11-16. PMID:28094812. |
we conclude that, whereas some mrna changes are consistent with increased dopamine action (decreased dat mrna), others suggest reduced dopamine action (increased maoa mrna) in the midbrain in schizophrenia. |
2017-11-16 |
2023-08-13 |
human |
| T D Purves-Tyson, S J Owens, D A Rothmond, G M Halliday, K L Double, J Stevens, T McCrossin, C Shannon Weicker. Putative presynaptic dopamine dysregulation in schizophrenia is supported by molecular evidence from post-mortem human midbrain. Translational psychiatry. vol 7. issue 1. 2017-11-16. PMID:28094812. |
here, we identify a molecular signature of dopamine dysregulation in the midbrain in schizophrenia that mainly includes gene expression changes of molecules involved in dopamine synthesis and in regulating the time course of dopamine action. |
2017-11-16 |
2023-08-13 |
human |
| Mike Ludwig, David Apps, John Menzies, Jyoti C Patel, Margaret E Ric. Dendritic Release of Neurotransmitters. Comprehensive Physiology. vol 7. issue 1. 2017-11-16. PMID:28135005. |
this review is focused on hypothalamic neuroendocrine cells that release vasopressin and oxytocin and midbrain neurons that release dopamine. |
2017-11-16 |
2023-08-13 |
Not clear |
| Anne-Sophie Rolland, Tatyana Kareva, Nikolai Kholodilov, Robert E Burk. A quantitative evaluation of a 2.5-kb rat tyrosine hydroxylase promoter to target expression in ventral mesencephalic dopamine neurons in vivo. Neuroscience. vol 346. 2017-11-09. PMID:28108256. |
one population of neurons that plays a central role in human neurodegenerative and psychiatric diseases are the dopamine neurons of the midbrain. |
2017-11-09 |
2023-08-13 |
human |
| Rebecca Playne, Bronwen Conno. Understanding Parkinson's Disease through the Use of Cell Reprogramming. Stem cell reviews and reports. vol 13. issue 2. 2017-11-06. PMID:28083784. |
however, the generation of high yields of functionally mature, authentic ventral midbrain dopamine (vmda) neurons has not been easy to achieve. |
2017-11-06 |
2023-08-13 |
human |
| Parisa Farzanehfar, Malcolm K Horne, Tim D Auman. An investigation of gene expression in single cells derived from Nestin-expressing cells in the adult mouse midbrain in vivo. Neuroscience letters. vol 648. 2017-11-06. PMID:28363755. |
generation of new dopamine (da) neurons in the adult midbrain is a controversial issue in development of better treatments for parkinson's disease (pd). |
2017-11-06 |
2023-08-13 |
mouse |
| Hideyuki Matsumoto, Ju Tian, Naoshige Uchida, Mitsuko Watabe-Uchid. Midbrain dopamine neurons signal aversion in a reward-context-dependent manner. eLife. vol 5. 2017-11-03. PMID:27760002. |
midbrain dopamine neurons signal aversion in a reward-context-dependent manner. |
2017-11-03 |
2023-08-13 |
mouse |
| Simone Engelender, Ole Isacso. The Threshold Theory for Parkinson's Disease. Trends in neurosciences. vol 40. issue 1. 2017-11-03. PMID:27894611. |
this is due to the larger functional reserve of the midbrain dopamine and integrated basal ganglia motor systems to control movement. |
2017-11-03 |
2023-08-13 |
Not clear |
| Michael Verwey, Alanna Grant, Nicholas Meti, Lauren Adye-White, Angelica Torres-Berrío, Veronique Rioux, Martin Lévesque, Frederic Charron, Cecilia Flore. Mesocortical Dopamine Phenotypes in Mice Lacking the Sonic Hedgehog Receptor Cdon. eNeuro. vol 3. issue 3. 2017-10-31. PMID:27419218. |
the morphogen sonic hedgehog (shh) specifies fates of midbrain dopamine neurons, but vta-specific effects of shh signaling are also being uncovered. |
2017-10-31 |
2023-08-13 |
mouse |
| Michael Verwey, Alanna Grant, Nicholas Meti, Lauren Adye-White, Angelica Torres-Berrío, Veronique Rioux, Martin Lévesque, Frederic Charron, Cecilia Flore. Mesocortical Dopamine Phenotypes in Mice Lacking the Sonic Hedgehog Receptor Cdon. eNeuro. vol 3. issue 3. 2017-10-31. PMID:27419218. |
based on these data, we suggest that cdon plays an important role encoding the diversity of dopamine neurons in the midbrain, influencing both the development of the mesocortical dopamine pathway and behavioral outputs that involve this neural circuitry. |
2017-10-31 |
2023-08-13 |
mouse |
| Joseph R Trinko, Benjamin B Land, Wojciech B Solecki, Robert J Wickham, Luis A Tellez, Jaime Maldonado-Aviles, Ivan E de Araujo, Nii A Addy, Ralph J DiLeon. Vitamin D3: A Role in Dopamine Circuit Regulation, Diet-Induced Obesity, and Drug Consumption. eNeuro. vol 3. issue 2. 2017-10-20. PMID:27257625. |
dopamine neurons in the midbrain and their target neurons in the striatum were found to express vitamin d3 receptor protein. |
2017-10-20 |
2023-08-13 |
mouse |
| Liana Fattore, Marco Dian. Drug addiction: An affective-cognitive disorder in need of a cure. Neuroscience and biobehavioral reviews. vol 65. 2017-10-19. PMID:27095547. |
the major elements of persistent compulsive drug use are hypothesized to be structural, cellular and molecular that underlie enduring changes in several forebrain circuits that receive input from midbrain dopamine neurons and are involved in affective (e.g. |
2017-10-19 |
2023-08-13 |
human |
| Natalia Omelchenko, Priya Roy, Judith Joyce Balcita-Pedicino, Samuel Poloyac, Susan R Sesac. Impact of prenatal nicotine on the structure of midbrain dopamine regions in the rat. Brain structure & function. vol 221. issue 4. 2017-10-03. PMID:25716298. |
impact of prenatal nicotine on the structure of midbrain dopamine regions in the rat. |
2017-10-03 |
2023-08-13 |
human |
| Natalia Omelchenko, Priya Roy, Judith Joyce Balcita-Pedicino, Samuel Poloyac, Susan R Sesac. Impact of prenatal nicotine on the structure of midbrain dopamine regions in the rat. Brain structure & function. vol 221. issue 4. 2017-10-03. PMID:25716298. |
certain sequelae of prenatal nic exposure suggest an impact on the development of the midbrain dopamine (da) system, which receives a robust cholinergic innervation from the mesopontine tegmentum. |
2017-10-03 |
2023-08-13 |
human |
| Hong-Yuan Chu, Eileen L McIver, Ryan F Kovaleski, Jeremy F Atherton, Mark D Beva. Loss of Hyperdirect Pathway Cortico-Subthalamic Inputs Following Degeneration of Midbrain Dopamine Neurons. Neuron. vol 95. issue 6. 2017-10-03. PMID:28910619. |
loss of hyperdirect pathway cortico-subthalamic inputs following degeneration of midbrain dopamine neurons. |
2017-10-03 |
2023-08-13 |
mouse |
| Yuji K Takahashi, Hannah M Batchelor, Bing Liu, Akash Khanna, Marisela Morales, Geoffrey Schoenbau. Dopamine Neurons Respond to Errors in the Prediction of Sensory Features of Expected Rewards. Neuron. vol 95. issue 6. 2017-10-03. PMID:28910622. |
midbrain dopamine neurons have been proposed to signal prediction errors as defined in model-free reinforcement learning algorithms. |
2017-10-03 |
2023-08-13 |
Not clear |
| Jameason D Cameron, Jean-Philippe Chaput, Anders M Sjödin, Gary S Goldfiel. Brain on Fire: Incentive Salience, Hedonic Hot Spots, Dopamine, Obesity, and Other Hunger Games. Annual review of nutrition. vol 37. 2017-10-02. PMID:28564556. |
this review examines human feeding behavior in light of psychological motivational theory and highlights the importance of midbrain dopamine (da). |
2017-10-02 |
2023-08-13 |
human |
| Stephanie C Gantz, Bruce P Bea. Cell-Autonomous Excitation of Midbrain Dopamine Neurons by Endocannabinoid-Dependent Lipid Signaling. Neuron. vol 93. issue 6. 2017-09-29. PMID:28262417. |
cell-autonomous excitation of midbrain dopamine neurons by endocannabinoid-dependent lipid signaling. |
2017-09-29 |
2023-08-13 |
mouse |
| Stephanie C Gantz, Bruce P Bea. Cell-Autonomous Excitation of Midbrain Dopamine Neurons by Endocannabinoid-Dependent Lipid Signaling. Neuron. vol 93. issue 6. 2017-09-29. PMID:28262417. |
using a preparation of dissociated mouse midbrain dopamine neurons to isolate effects on intrinsic excitability, we found that 100 nm 2-ag accelerated pacemaking and steepened the frequency-current relationship for burst-like firing. |
2017-09-29 |
2023-08-13 |
mouse |