| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ming-Hua Li, Suzanne M Underhill, Cheryl Reed, Tamara J Phillips, Susan G Amara, Susan L Ingra. Amphetamine and Methamphetamine Increase NMDAR-GluN2B Synaptic Currents in Midbrain Dopamine Neurons. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 42. issue 7. 2018-01-12. PMID:27976681. |
these results reveal an important interaction between dopamine and glutamatergic signaling in midbrain dopamine neurons in response to acute administration of psychostimulants. |
2018-01-12 |
2023-08-13 |
Not clear |
| Federico N Soria, Michel Engeln, Marta Martinez-Vicente, Christelle Glangetas, María José López-González, Sandra Dovero, Benjamin Dehay, Elisabeth Normand, Miquel Vila, Alexandre Favereaux, François Georges, Christophe Lo Bianco, Erwan Bezard, Pierre-Olivier Fernagu. Glucocerebrosidase deficiency in dopaminergic neurons induces microglial activation without neurodegeneration. Human molecular genetics. vol 26. issue 14. 2018-01-11. PMID:28520872. |
dat-cre and gba1-floxed mice were bred to obtain selective homozygous disruption of gba1 in midbrain dopamine neurons (dat-gba1-ko). |
2018-01-11 |
2023-08-13 |
mouse |
| Yong Sang Jo, Sheri J Y Mizumor. Prefrontal Regulation of Neuronal Activity in the Ventral Tegmental Area. Cerebral cortex (New York, N.Y. : 1991). vol 26. issue 10. 2018-01-10. PMID:26400913. |
growing evidence indicates that midbrain dopamine (da) cells integrate reward expectancy-related information from the prefrontal cortex to properly compute errors in reward prediction. |
2018-01-10 |
2023-08-13 |
rat |
| Yong Sang Jo, Sheri J Y Mizumor. Prefrontal Regulation of Neuronal Activity in the Ventral Tegmental Area. Cerebral cortex (New York, N.Y. : 1991). vol 26. issue 10. 2018-01-10. PMID:26400913. |
these results suggest that the 2 prefrontal subregions differentially regulate daergic prediction errors and the ofc conveys value signals to midbrain dopamine systems. |
2018-01-10 |
2023-08-13 |
rat |
| Rahul Pandit, Azar Omrani, Mieneke C M Luijendijk, Véronne A J de Vrind, Andrea J Van Rozen, Ralph J A Oude Ophuis, Keith Garner, Imre Kallo, Alexander Ghanem, Zsolt Liposits, Karl-Klaus Conzelmann, Louk J M J Vanderschuren, Susanne E la Fleur, Roger A H Ada. Melanocortin 3 Receptor Signaling in Midbrain Dopamine Neurons Increases the Motivation for Food Reward. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 41. issue 9. 2018-01-09. PMID:26852738. |
melanocortin 3 receptor signaling in midbrain dopamine neurons increases the motivation for food reward. |
2018-01-09 |
2023-08-13 |
rat |
| Matthew Brodsky, Alec W Gibson, Denis Smirnov, Sunila G Nair, John F Neumaie. Striatal 5-HT6 Receptors Regulate Cocaine Reinforcement in a Pathway-Selective Manner. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 41. issue 9. 2018-01-09. PMID:27032690. |
the nucleus accumbens (nac) in the ventral striatum integrates many neurochemical inputs including dopamine and serotonin projections from midbrain nuclei to modulate drug reward. |
2018-01-09 |
2023-08-13 |
rat |
| Scott W Lallier, Amanda E Graf, Gavisha R Waidyarante, Lynette K Roger. Nurr1 expression is modified by inflammation in microglia. Neuroreport. vol 27. issue 15. 2018-01-08. PMID:27532877. |
nurr1 (nr4a2) is an orphan nuclear receptor with no known binding site and is essential for the growth of midbrain dopamine neurons. |
2018-01-08 |
2023-08-13 |
mouse |
| Cody A Siciliano, Jason L Locke, Tiffany A Mathews, Marcelo F Lopez, Howard C Becker, Sara R Jone. Dopamine synthesis in alcohol drinking-prone and -resistant mouse strains. Alcohol (Fayetteville, N.Y.). vol 58. 2018-01-03. PMID:27425261. |
by administering an l-aromatic acid decarboxylase inhibitor and measuring l-dopa accumulation via high-performance liquid chromatography as a measure of tyrosine hydroxylase activity, we found no difference in dopamine synthesis between mouse strains in the midbrain, dorsal striatum, or ventral striatum. |
2018-01-03 |
2023-08-13 |
mouse |
| Maggie C Evans, Greg M Anderso. Dopamine Neuron-Restricted Leptin Receptor Signaling Reduces Some Aspects of Food Reward but Exacerbates the Obesity of Leptin Receptor-Deficient Male Mice. Endocrinology. vol 158. issue 12. 2017-12-18. PMID:28938472. |
midbrain dopamine neurons regulate the reward value of food, and direct leptin administration to the midbrain reduces food intake. |
2017-12-18 |
2023-08-13 |
mouse |
| Terry Lohrenz, Kenneth T Kishida, P Read Montagu. BOLD and its connection to dopamine release in human striatum: a cross-cohort comparison. Philosophical transactions of the Royal Society of London. Series B, Biological sciences. vol 371. issue 1705. 2017-11-30. PMID:27574306. |
activity in midbrain dopamine neurons modulates the release of dopamine in terminal structures including the striatum, and controls reward-dependent valuation and choice. |
2017-11-30 |
2023-08-13 |
human |
| Benjamin B Tournier, Stergios Tsartsalis, Andrea Dimiziani, Philippe Millet, Nathalie Ginovar. Time-dependent effects of repeated THC treatment on dopamine D2/3 receptor-mediated signalling in midbrain and striatum. Behavioural brain research. vol 311. 2017-11-27. PMID:27233824. |
time-dependent effects of repeated thc treatment on dopamine d2/3 receptor-mediated signalling in midbrain and striatum. |
2017-11-27 |
2023-08-13 |
rat |
| Benjamin B Tournier, Stergios Tsartsalis, Andrea Dimiziani, Philippe Millet, Nathalie Ginovar. Time-dependent effects of repeated THC treatment on dopamine D2/3 receptor-mediated signalling in midbrain and striatum. Behavioural brain research. vol 311. 2017-11-27. PMID:27233824. |
thc-induced d2/3r alterations were more pronounced and longer lasting in the dopamine cell body regions of the midbrain, wherein [(3)h]-(+)-phno binding was still elevated at 2 weeks but back to control values at 6 weeks after thc cessation. |
2017-11-27 |
2023-08-13 |
rat |
| Elsa Vera, Nazario Bosco, Lorenz Stude. Generating Late-Onset Human iPSC-Based Disease Models by Inducing Neuronal Age-Related Phenotypes through Telomerase Manipulation. Cell reports. vol 17. issue 4. 2017-11-24. PMID:27760320. |
we show that shortened telomeres result in age-associated as well as potentially disease-associated phenotypes in human pluripotent stem cell (hpsc)-derived midbrain dopamine (mda) neurons. |
2017-11-24 |
2023-08-13 |
human |
| Sun Young Chung, Sarah Kishinevsky, Joseph R Mazzulli, John Graziotto, Ana Mrejeru, Eugene V Mosharov, Lesly Puspita, Parvin Valiulahi, David Sulzer, Teresa A Milner, Tony Taldone, Dimitri Krainc, Lorenz Studer, Jae-Won Shi. Parkin and PINK1 Patient iPSC-Derived Midbrain Dopamine Neurons Exhibit Mitochondrial Dysfunction and α-Synuclein Accumulation. Stem cell reports. vol 7. issue 4. 2017-11-21. PMID:27641647. |
parkin and pink1 patient ipsc-derived midbrain dopamine neurons exhibit mitochondrial dysfunction and α-synuclein accumulation. |
2017-11-21 |
2023-08-13 |
Not clear |
| Sun Young Chung, Sarah Kishinevsky, Joseph R Mazzulli, John Graziotto, Ana Mrejeru, Eugene V Mosharov, Lesly Puspita, Parvin Valiulahi, David Sulzer, Teresa A Milner, Tony Taldone, Dimitri Krainc, Lorenz Studer, Jae-Won Shi. Parkin and PINK1 Patient iPSC-Derived Midbrain Dopamine Neurons Exhibit Mitochondrial Dysfunction and α-Synuclein Accumulation. Stem cell reports. vol 7. issue 4. 2017-11-21. PMID:27641647. |
we demonstrate that the identification of disease-related phenotypes in pd-patient-specific induced pluripotent stem cell (ipsc)-derived midbrain dopamine (mda) neurons depends on the type of differentiation protocol utilized. |
2017-11-21 |
2023-08-13 |
Not clear |
| Andon N Placzek, Gonzalo Viana Di Prisco, Sanjeev Khatiwada, Martina Sgritta, Wei Huang, Krešimir Krnjević, Randal J Kaufman, John A Dani, Peter Walter, Mauro Costa-Mattiol. eIF2α-mediated translational control regulates the persistence of cocaine-induced LTP in midbrain dopamine neurons. eLife. vol 5. 2017-11-20. PMID:27960077. |
eif2α-mediated translational control regulates the persistence of cocaine-induced ltp in midbrain dopamine neurons. |
2017-11-20 |
2023-08-13 |
mouse |
| Travis A Hage, Yujie Sun, Zayd M Khali. Electrical and Ca(2+) signaling in dendritic spines of substantia nigra dopaminergic neurons. eLife. vol 5. 2017-11-16. PMID:27163179. |
little is known about the density and function of dendritic spines on midbrain dopamine neurons, or the relative contribution of spine and shaft synapses to excitability. |
2017-11-16 |
2023-08-13 |
mouse |
| Kanwar Virdee, Jiska Kentrop, Bianca Jupp, Bethany Venus, Daniel Hensman, Simon McArthur, James Wilkinson, Trevor W Robbins, Glenda Gillies, Jeffrey W Dalle. Counteractive effects of antenatal glucocorticoid treatment on D1 receptor modulation of spatial working memory. Psychopharmacology. vol 233. issue 21-22. 2017-11-16. PMID:27553822. |
however, the consequences of this expansion in midbrain dopamine (da) neurons for behavioural processes in adulthood are poorly understood, including working memory that depends on da transmission in the prefrontal cortex (pfc). |
2017-11-16 |
2023-08-13 |
rat |
| T D Purves-Tyson, S J Owens, D A Rothmond, G M Halliday, K L Double, J Stevens, T McCrossin, C Shannon Weicker. Putative presynaptic dopamine dysregulation in schizophrenia is supported by molecular evidence from post-mortem human midbrain. Translational psychiatry. vol 7. issue 1. 2017-11-16. PMID:28094812. |
putative presynaptic dopamine dysregulation in schizophrenia is supported by molecular evidence from post-mortem human midbrain. |
2017-11-16 |
2023-08-13 |
human |
| T D Purves-Tyson, S J Owens, D A Rothmond, G M Halliday, K L Double, J Stevens, T McCrossin, C Shannon Weicker. Putative presynaptic dopamine dysregulation in schizophrenia is supported by molecular evidence from post-mortem human midbrain. Translational psychiatry. vol 7. issue 1. 2017-11-16. PMID:28094812. |
in vivo imaging studies indicate an increased presynaptic dopamine synthesis capacity in striatal terminals and cell bodies in the midbrain in schizophrenia; however, measures of the dopamine-synthesising enzyme, tyrosine hydroxylase (th), have not identified consistent changes. |
2017-11-16 |
2023-08-13 |
human |