| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Randall J Olson, Lowell Bartlett, Alex Sonneborn, Russell Milton, Zachary Bretton-Granatoor, Ayesha Firdous, Alexander Z Harris, Atheir I Abba. Decoupling of cortical activity from behavioral state following administration of the classic psychedelic DOI. Neuropharmacology. 2024-06-08. PMID:38851531. |
the medial prefrontal cortex (mpfc), where cps have been shown to induce rapid, 5-ht |
2024-06-08 |
2024-06-11 |
Not clear |
| Aniruddha Deka, Emmanuel Joseph, Neha Sharma, Tirsit Berhanu, Jonathan Kapla. Recurrent Serotonin Syndrome After Ketamine-assisted Electroconvulsive Therapy: A Case Report and Review of the Literature. Journal of psychiatric practice. vol 30. issue 3. 2024-05-31. PMID:38819248. |
ketamine increases α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid activity in the medial prefrontal cortex, which leads to downstream 5-ht release through glutamate. |
2024-05-31 |
2024-06-06 |
Not clear |
| Hiro Taiyo Hamada, Yoshifumi Abe, Norio Takata, Masakazu Taira, Kenji F Tanaka, Kenji Doy. Optogenetic activation of dorsal raphe serotonin neurons induces brain-wide activation. Nature communications. vol 15. issue 1. 2024-05-16. PMID:38755120. |
transient activation of drn serotonin neurons caused brain-wide activation, including the medial prefrontal cortex, the striatum, and the ventral tegmental area. |
2024-05-16 |
2024-05-27 |
mouse |
| Huihui Tan, Chengxue Du, Li Zhang, Yuan Guo, Yaxin Yang, Qingfeng Sun, Qiaojun Zhang, Libo L. Lesions of the lateral habenula excite dopamine neurons in the ventral tegmental area and serotonin neurons in the dorsal raphe nuclei in hemiparkinsonian rats. Brain research. 2024-04-08. PMID:38588847. |
the lateral habenula (lhb) projects to the ventral tegmental area (vta) and dorsal raphe nuclei (drn) that deliver dopamine (da) and serotonin (5-ht) to cortical and limbic regions such as the medial prefrontal cortex (mpfc), hippocampus and basolateral amygdala (bla). |
2024-04-08 |
2024-04-11 |
rat |
| Linlin Zhang, Yuanyuan Chen, Yongzhao Fan, Lin Sh. Treadmill exercise pretreatment ameliorated structural synaptic plasticity impairments of medial prefrontal cortex in vascular dementia rat and improved recognition memory. Scientific reports. vol 14. issue 1. 2024-03-27. PMID:38531892. |
finally, microdialysis coupled with high-performance liquid chromatography was used to assess the levels of 5-ht and dopamine in the medial prefrontal cortex. |
2024-03-27 |
2024-03-29 |
rat |
| Linlin Zhang, Yuanyuan Chen, Yongzhao Fan, Lin Sh. Treadmill exercise pretreatment ameliorated structural synaptic plasticity impairments of medial prefrontal cortex in vascular dementia rat and improved recognition memory. Scientific reports. vol 14. issue 1. 2024-03-27. PMID:38531892. |
lastly, the levels of dopamine and 5-ht in the medial prefrontal cortex of rats in the vd group was significantly lower compared to the con group (p < 0.01), and treadmill exercise was shown to significantly increased the levels of dopamine and 5-ht in the vd rats (p < 0.05). |
2024-03-27 |
2024-03-29 |
rat |
| Jia-Ya Zheng, Xue-Xin Li, Xiao Liu, Chen-Chen Zhang, Ya-Xin Sun, Yu-Nu Ma, Hong-Li Wang, Yun-Ai Su, Tian-Mei Si, Ji-Tao L. Fluoxetine reverses early-life stress-induced depressive-like behaviors and region-specific alterations of monoamine transporters in female mice. Pharmacology, biochemistry, and behavior. 2024-02-09. PMID:38336220. |
at the molecular level, we largely replicated the es effects, such as reduced serotonin transporter (sert) expression in the amygdala and increased norepinephrine transporter (net) expression in the medial prefrontal cortex (mpfc) and hippocampus. |
2024-02-09 |
2024-02-12 |
mouse |
| Sen Yang, Qiang Zheng, Guoan Yi. A 24-h restraint with food and water deprivation: a potential method to establish a model of depression in pigs. Frontiers in veterinary science. vol 10. 2023-10-26. PMID:37876629. |
the levels of cor and acth in the serum and the levels of 5-ht, ne, and bdnf in the hippocampus and medial prefrontal cortex were detected using elisa to identify the physiological state. |
2023-10-26 |
2023-11-08 |
Not clear |
| Fang Lin, Xinyuan Wang, Ruifang Luo, Binlin Yuan, Shasha Ye, Ting Yang, Lu Xiao, Jie Che. Maternal LPS Exposure Enhances the 5-HT Level in the Prefrontal Cortex of Autism-like Young Offspring. Brain sciences. vol 13. issue 6. 2023-06-28. PMID:37371436. |
the aim of this research is to investigate the changes in serotonin (5-ht) in the medial prefrontal cortex (pfc) of autism-like offspring induced by maternal lipopolysaccharide (lps) exposure. |
2023-06-28 |
2023-08-14 |
rat |
| Saida Oubraim, Roh-Yu Shen, Samir Haj-Dahman. Oxytocin excites dorsal raphe serotonin neurons and bidirectionally gates their glutamate synapses. iScience. vol 26. issue 5. 2023-05-30. PMID:37250336. |
neuronal mapping demonstrates that oxt preferentially potentiates glutamate synapses of 5-ht neurons projecting to medial prefrontal cortex (mpfc) and depresses glutamatergic inputs to 5-ht neurons projecting to lateral habenula (lhb) and central amygdala (cea). |
2023-05-30 |
2023-08-14 |
Not clear |
| Ashlea A Morgan, Nuno D Alves, Gregory S Stevens, Tamanna T Yeasmin, Alexandra Mackay, Saige Power, Derya Sargin, Carla Hanna, Arwa L Adib, Annette Ziolkowski-Blake, Evelyn K Lambe, Mark S Ansorg. Medial Prefrontal Cortex Serotonin Input Regulates Cognitive Flexibility in Mice. bioRxiv : the preprint server for biology. 2023-04-10. PMID:37034804. |
medial prefrontal cortex serotonin input regulates cognitive flexibility in mice. |
2023-04-10 |
2023-08-14 |
mouse |
| James W M Kang, Kevin A Keay, Michael D Kendig, Laura H Corbit, David Mo. Serotonin and Dopamine Show Different Response Profiles to Acute Stress in the Nucleus Accumbens and Medial Prefrontal Cortex of Rats with Neuropathic Pain. Neurochemical research. 2023-03-21. PMID:36941432. |
serotonin and dopamine show different response profiles to acute stress in the nucleus accumbens and medial prefrontal cortex of rats with neuropathic pain. |
2023-03-21 |
2023-08-14 |
rat |
| James W M Kang, Kevin A Keay, Michael D Kendig, Laura H Corbit, David Mo. Serotonin and Dopamine Show Different Response Profiles to Acute Stress in the Nucleus Accumbens and Medial Prefrontal Cortex of Rats with Neuropathic Pain. Neurochemical research. 2023-03-21. PMID:36941432. |
cci alone significantly decreased dopamine but not serotonin concentrations in the medial prefrontal cortex. |
2023-03-21 |
2023-08-14 |
rat |
| James W M Kang, Kevin A Keay, Michael D Kendig, Laura H Corbit, David Mo. Serotonin and Dopamine Show Different Response Profiles to Acute Stress in the Nucleus Accumbens and Medial Prefrontal Cortex of Rats with Neuropathic Pain. Neurochemical research. 2023-03-21. PMID:36941432. |
by contrast, restraint stress acutely increased dopamine in the medial prefrontal cortex, and the nucleus accumbens; and increased serotonin in the medial prefrontal cortex 2 h later. |
2023-03-21 |
2023-08-14 |
rat |
| Hirohito Esaki, Yuki Sasaki, Naoya Nishitani, Hikari Kamada, Satoko Mukai, Yoshitaka Ohshima, Sao Nakada, Xiyan Ni, Satoshi Deyama, Katsuyuki Kaned. Role of 5-HT European journal of pharmacology. 2023-03-12. PMID:36907260. |
in the present study, we investigated whether 5-ht neurotransmission in the medial prefrontal cortex (mpfc) and the basolateral nucleus of amygdala (bla) is involved in mdma-induced prosocial effects using the social approach test in male icr mice. |
2023-03-12 |
2023-08-14 |
mouse |
| Anna Portugalov, Hiba Zaidan, Inna Gaisler-Salomon, Cecilia J Hillard, Irit Akira. FAAH Inhibition Restores Early Life Stress-Induced Alterations in PFC microRNAs Associated with Depressive-Like Behavior in Male and Female Rats. International journal of molecular sciences. vol 23. issue 24. 2022-12-23. PMID:36555739. |
we compared the effects of treatment with the fatty acid amide hydrolase (faah) inhibitor urb597, and the selective serotonin reuptake inhibitor paroxetine, on els-induced depressive-like behavior and the expression of micrornas (mirs) associated with depression in the medial prefrontal cortex (mpfc), hippocampal ca1 area, lateral habenula and dorsal raphe in rats. |
2022-12-23 |
2023-08-14 |
rat |
| Bongjun Sur, Bombi Le. Luteolin reduces fear, anxiety, and depression in rats with post-traumatic stress disorder. Animal cells and systems. vol 26. issue 4. 2022-09-01. PMID:36046028. |
also, administration of lu restored the increased norepinephrine and decreased serotonin levels in the structures within the fear circuit, medial prefrontal cortex, and hippocampus. |
2022-09-01 |
2023-08-14 |
rat |
| Laura Durieux, Karine Herbeaux, Christopher Borcuk, Cécile Hildenbrand, Virginie Andry, Yannick Goumon, Alexandra Barbelivien, Chantal Mathis, Demian Bataglia, Monique Majchrzak, Lucas Lecourtie. Functional brain-wide network mapping during acute stress exposure in rats: Interaction between the lateral habenula and cortical, amygdalar, hypothalamic and monoaminergic regions. The European journal of neuroscience. 2022-08-22. PMID:35993349. |
it has been known for decades that the main structures engaged during the stress response are the medial prefrontal cortex, the amygdala, the hippocampus, the hypothalamus, the monoaminergic systems (noradrenaline, dopamine, serotonin), and the periaqueductal gray. |
2022-08-22 |
2023-08-14 |
rat |
| Bongjun Sur, Bombi Le. Myricetin Inhibited Fear and Anxiety-Like Behaviors by HPA Axis Regulation and Activation of the BDNF-ERK Signaling Pathway in Posttraumatic Stress Disorder Rats. Evidence-based complementary and alternative medicine : eCAM. vol 2022. 2022-06-20. PMID:35722162. |
also, administration of myr restored decreased serotonin and increased norepinephrine in the fear circuit regions, medial prefrontal cortex, and hippocampus. |
2022-06-20 |
2023-08-14 |
rat |
| Lakshmi Rajagopal, Mei Huang, Wenqi He, Chelsea Ryan, Ahmad Elzokaky, Pradeep Banerjee, Herbert Y Meltze. Repeated administration of rapastinel produces exceptionally prolonged rescue of memory deficits in phencyclidine-treated mice. Behavioural brain research. 2022-06-19. PMID:35718230. |
both rapastinel (3mg/kg) and ketamine (30mg/kg), moderately increased the efflux of dopamine, norepinephrine, and serotonin in medial prefrontal cortex; however, only ketamine increased cortical glutamate efflux. |
2022-06-19 |
2023-08-14 |
mouse |