| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Iu O Fedotova, N A Platonova, N S Saprono. [8-OH-DPAT modulates expression of 5-HT(1A)/5-HT(2A), 17beta-estradiol receptor mRNAs in ovariectomized rats in Porsolt test]. Eksperimental'naia i klinicheskaia farmakologiia. vol 69. issue 3. 2006-09-25. PMID:16878502. |
simultaneously, 8-oh-dpat induced significant increase of 5-ht(1a)-, 5-ht(2a)-receptors mrnas expression and decrease of 17beta-estradiol receptor mrna expression in hippocampus in ovx rats as compared to the control. |
2006-09-25 |
2023-08-12 |
rat |
| Bart Stragier, Ralph Clinckers, Alfred Meurs, Dimitri De Bundel, Sophie Sarre, Guy Ebinger, Yvette Michotte, Ilse Smolder. Involvement of the somatostatin-2 receptor in the anti-convulsant effect of angiotensin IV against pilocarpine-induced limbic seizures in rats. Journal of neurochemistry. vol 98. issue 4. 2006-09-21. PMID:16771832. |
administered ang iv or somatostatin-14 caused a significant increase in the hippocampal extracellular dopamine and serotonin levels and protected rats against pilocarpine-induced seizures. |
2006-09-21 |
2023-08-12 |
rat |
| Taku Sato, Eiji Suzuki, Masamoto Yokoyama, Jun'ichi Semba, Shigeru Watanabe, Hitoshi Miyaok. Chronic intraperitoneal injection of interferon-alpha reduces serotonin levels in various regions of rat brain, but does not change levels of serotonin transporter mRNA, nitrite or nitrate. Psychiatry and clinical neurosciences. vol 60. issue 4. 2006-09-20. PMID:16884454. |
after 14 days, serotonin turnover was increased in the frontal cortex and hippocampus in rats given a dose of 20 000 iu/kg; in the frontal cortex, hippocampus, amygdala, thalamus, hypothalamus and brainstem in those on 200 000 iu/kg; and in the thalamus and hypothalamus in those on 2 000 000 iu/kg (all p < 0.05). |
2006-09-20 |
2023-08-12 |
rat |
| J Douglas Bremne. The relationship between cognitive and brain changes in posttraumatic stress disorder. Annals of the New York Academy of Sciences. vol 1071. 2006-09-20. PMID:16891564. |
studies in animals showed that both serotonin reuptake inhibitors (ssris) and the epilepsy medication phenytoin (dilantin) block the effects of stress on the hippocampus. |
2006-09-20 |
2023-08-12 |
Not clear |
| Robert Grossman, Rachel Yehuda, Julia Golier, Bruce McEwen, Philip Harvey, Nelly Sta Mari. Cognitive effects of intravenous hydrocortisone in subjects with PTSD and healthy control subjects. Annals of the New York Academy of Sciences. vol 1071. 2006-09-20. PMID:16891588. |
heightened vulnerability of declarative memory in subjects with ptsd may indicate hippocampal involvement, whereas working memory vulnerability suggests additional brain regions (prefrontal, cingulate, temporal, and parietal cortices) and neurotransmitter systems (dopamine and serotonin) particularly sensitive to glucocorticoids in persons with ptsd. |
2006-09-20 |
2023-08-12 |
human |
| Ghanshyam N Pandey, Yogesh Dwivedi, Xinguo Ren, Hooriyah S Rizavi, Gabor Faludi, Andrea Sarosi, Miklos Palkovit. Regional distribution and relative abundance of serotonin(2c) receptors in human brain: effect of suicide. Neurochemical research. vol 31. issue 2. 2006-09-19. PMID:16673176. |
we examined the regional distribution of serotonin (5ht)(2c) receptor mrna in several areas of the human brain and also compared its protein and mrna expression in the prefrontal cortex (pfc), hippocampus, and choroid plexus between suicide victims and normal control subjects. |
2006-09-19 |
2023-08-12 |
human |
| Ghanshyam N Pandey, Yogesh Dwivedi, Xinguo Ren, Hooriyah S Rizavi, Gabor Faludi, Andrea Sarosi, Miklos Palkovit. Regional distribution and relative abundance of serotonin(2c) receptors in human brain: effect of suicide. Neurochemical research. vol 31. issue 2. 2006-09-19. PMID:16673176. |
comparison of 5ht(2c) receptors between suicide victims and control subjects showed higher protein levels in the pfc but not the hippocampus or choroid plexus of suicide victims. |
2006-09-19 |
2023-08-12 |
human |
| Sven Ove Ogren, Eugenia Kuteeva, Tomas Hökfelt, Jan Keh. Galanin receptor antagonists : a potential novel pharmacological treatment for mood disorders. CNS drugs. vol 20. issue 8. 2006-09-19. PMID:16863269. |
studies in rats have shown that galanin administered intracerebroventricularly is a potent inhibitor of mesencephalic serotonergic neurotransmission, as indicated by a long-lasting reduction in the release of serotonin in the hippocampus. |
2006-09-19 |
2023-08-12 |
mouse |
| Sven Ove Ogren, Eugenia Kuteeva, Tomas Hökfelt, Jan Keh. Galanin receptor antagonists : a potential novel pharmacological treatment for mood disorders. CNS drugs. vol 20. issue 8. 2006-09-19. PMID:16863269. |
on the other hand, stimulation of the gal2 receptor at the raphe level by local application of the gal2 receptor agonist galanin (2-11) has been shown to increase serotonin levels in the hippocampus and dorsal raphe. |
2006-09-19 |
2023-08-12 |
mouse |
| Carol A Tamming. The neurobiology of cognition in schizophrenia. The Journal of clinical psychiatry. vol 67 Suppl 9. 2006-09-19. PMID:16965183. |
those targets that show promise for pharmacologic focus include the dopamine receptors (especially d1) in the prefrontal cortex (pfc), the serotonin receptors in the pfc and anterior cingulate cortex, the glutamatergic excitatory synapse, the acetylcholine nicotinic receptors in the hippocampus, the acetylcholine muscarinic receptors, and the brain gamma-aminobutyric acid (gaba) system. |
2006-09-19 |
2023-08-12 |
Not clear |
| Neeltje G van Gemert, Els van Riel, Onno C Meijer, Susanne Fehr, Melitta Schachner, Marian Joël. No effect of prolonged corticosterone over-exposure on NCAM, SGK1, and RGS4 mRNA expression in rat hippocampus. Brain research. vol 1093. issue 1. 2006-09-12. PMID:16677622. |
we here tested if corticosterone changes 5-ht(1a) receptor function indirectly, by altering hippocampal mrna expression of ncam, sgk1, or rgs4, which all modulate 5-ht(1a) receptor function. |
2006-09-12 |
2023-08-12 |
rat |
| Joanna Dabrowska, Michal Brylinsk. Stereoselectivity of 8-OH-DPAT toward the serotonin 5-HT1A receptor: biochemical and molecular modeling study. Biochemical pharmacology. vol 72. issue 4. 2006-09-11. PMID:16796994. |
in the biochemical study capability of racemic 8-oh-dpat (0.05, 0.1 mg/kg s.c.) and its counterparts r-8-oh-dpat (0.05, 0.1 mg/kg s.c.) and s-8-oh-dpat (0.05, 0.1 mg/kg s.c.) to influence 5-ht synthesis rate in rats' prefrontal cortex, hypothalamus, hippocampus and brainstem was evaluated by hplc/ed technique. |
2006-09-11 |
2023-08-12 |
rat |
| Ville A B Palomäki, Jarmo T Laitine. The basic secretagogue compound 48/80 activates G proteins indirectly via stimulation of phospholipase D-lysophosphatidic acid receptor axis and 5-HT1A receptors in rat brain sections. British journal of pharmacology. vol 147. issue 6. 2006-09-07. PMID:16415902. |
in addition, c48/80 was found to modestly activate hippocampal 5-ht(1a) receptors in a ph-dependent and antagonist-sensitive manner. |
2006-09-07 |
2023-08-12 |
rat |
| Sarah Clark, Jennifer Schwalbe, Melissa R Stasko, Paul J Yarowsky, Alberto C S Cost. Fluoxetine rescues deficient neurogenesis in hippocampus of the Ts65Dn mouse model for Down syndrome. Experimental neurology. vol 200. issue 1. 2006-09-05. PMID:16624293. |
chronic antidepressant treatment for over 3 weeks with the serotonin selective reuptake inhibitor, fluoxetine, increased neurogenesis in the ts65dn to comparable levels seen in the euploid by augmenting both proliferation and survival of brdu-labeled cells in the subgranular layer and granule cell layer of the hippocampus, respectively. |
2006-09-05 |
2023-08-12 |
mouse |
| Susanne Rutz, Céline Riegert, Anna Katharina Rothmaier, Marie-Christine Buhot, Jean-Christophe Cassel, Rolf Jackisc. Presynaptic serotonergic modulation of 5-HT and acetylcholine release in the hippocampus and the cortex of 5-HT1B-receptor knockout mice. Brain research bulletin. vol 70. issue 1. 2006-09-05. PMID:16750486. |
presynaptic serotonergic modulation of 5-ht and acetylcholine release in the hippocampus and the cortex of 5-ht1b-receptor knockout mice. |
2006-09-05 |
2023-08-12 |
mouse |
| Susanne Rutz, Céline Riegert, Anna Katharina Rothmaier, Marie-Christine Buhot, Jean-Christophe Cassel, Rolf Jackisc. Presynaptic serotonergic modulation of 5-HT and acetylcholine release in the hippocampus and the cortex of 5-HT1B-receptor knockout mice. Brain research bulletin. vol 70. issue 1. 2006-09-05. PMID:16750486. |
improved memory performance described in 5-ht1b-knockout (ko) mice might thus be due to a weaker 5-ht1b-mediated inhibitory influence of 5-ht on hippocampal ach release. |
2006-09-05 |
2023-08-12 |
mouse |
| Susanne Rutz, Céline Riegert, Anna Katharina Rothmaier, Marie-Christine Buhot, Jean-Christophe Cassel, Rolf Jackisc. Presynaptic serotonergic modulation of 5-HT and acetylcholine release in the hippocampus and the cortex of 5-HT1B-receptor knockout mice. Brain research bulletin. vol 70. issue 1. 2006-09-05. PMID:16750486. |
to provide neuropharmacological support for these hypotheses we measured evoked ach and 5-ht release in hippocampal and cortical slices of wild-type (wt) and 5-ht1b ko mice. |
2006-09-05 |
2023-08-12 |
mouse |
| Susanne Rutz, Céline Riegert, Anna Katharina Rothmaier, Marie-Christine Buhot, Jean-Christophe Cassel, Rolf Jackisc. Presynaptic serotonergic modulation of 5-HT and acetylcholine release in the hippocampus and the cortex of 5-HT1B-receptor knockout mice. Brain research bulletin. vol 70. issue 1. 2006-09-05. PMID:16750486. |
in hippocampus and cortex, 5-ht1b agonists decreased and antagonists increased 5-ht release in wt, but not in 5-ht1b ko mice. |
2006-09-05 |
2023-08-12 |
mouse |
| Susanne Rutz, Céline Riegert, Anna Katharina Rothmaier, Marie-Christine Buhot, Jean-Christophe Cassel, Rolf Jackisc. Presynaptic serotonergic modulation of 5-HT and acetylcholine release in the hippocampus and the cortex of 5-HT1B-receptor knockout mice. Brain research bulletin. vol 70. issue 1. 2006-09-05. PMID:16750486. |
our data (i) confirm the absence of autoinhibition of 5-ht release in 5-ht1b-ko mice, (ii) demonstrate a reduced release of ach, and the absence of 5-ht1b-receptor-mediated inhibition of ach release, in the hippocampus and cortex of 5-ht1b-ko mice, and (iii) are compatible with an indirect role of cortical ach in the working memory impairment observed in these ko mice. |
2006-09-05 |
2023-08-12 |
mouse |
| Suzanne Cassel, Delphine Carouge, Claire Gensburger, Patrick Anglard, Claude Burgun, Jean-Bernard Dietrich, Dominique Aunis, Jean Zwille. Fluoxetine and cocaine induce the epigenetic factors MeCP2 and MBD1 in adult rat brain. Molecular pharmacology. vol 70. issue 2. 2006-08-28. PMID:16670375. |
the effect was characterized in three serotonin projection areas, the caudate-putamen, the frontal cortex, and the dentate gyrus subregion of hippocampus. |
2006-08-28 |
2023-08-12 |
rat |