| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Karen L Anderson, Yossef Itzha. Methamphetamine-induced selective dopaminergic neurotoxicity is accompanied by an increase in striatal nitrate in the mouse. Annals of the New York Academy of Sciences. vol 1074. 2007-01-10. PMID:17105919. |
administration of meth (5 mg/kg x 3) to swiss webster mice resulted in marked depletion of dopamine (da) and da transporter (dat) binding sites but no change in 5-hydroxytryptamine (5-ht) and 5-ht transporter (5-htt) binding sites in the striatum, amygdala, frontal cortex, and hippocampus, suggesting that meth causes selective neurotoxicity to da nerve terminals. |
2007-01-10 |
2023-08-12 |
mouse |
| H Husum, S Aznar, S Høyer-Hansen, M Hald Larsen, J D Mikkelsen, A Møller, A A Mathé, G Wörtwei. Exacerbated loss of cell survival, neuropeptide Y-immunoreactive (IR) cells, and serotonin-IR fiber lengths in the dorsal hippocampus of the aged flinders sensitive line "depressed" rat: Implications for the pathophysiology of depression? Journal of neuroscience research. vol 84. issue 6. 2007-01-04. PMID:17099915. |
the flinders-sensitive line (fsl) rat represents a genetic model of depression with characterized 5-ht and npy abnormalities in the hippocampus. |
2007-01-04 |
2023-08-12 |
rat |
| H Husum, S Aznar, S Høyer-Hansen, M Hald Larsen, J D Mikkelsen, A Møller, A A Mathé, G Wörtwei. Exacerbated loss of cell survival, neuropeptide Y-immunoreactive (IR) cells, and serotonin-IR fiber lengths in the dorsal hippocampus of the aged flinders sensitive line "depressed" rat: Implications for the pathophysiology of depression? Journal of neuroscience research. vol 84. issue 6. 2007-01-04. PMID:17099915. |
the aged fsl rats also had shortened 5-ht-ir fibers in the dorsal hippocampus, indicative of an impaired 5-ht innervation of this area, compared with frl. |
2007-01-04 |
2023-08-12 |
rat |
| Melinda Gyenge, Mónika Hantos, Rudolf Laufer, Korniléa Teke. [Effect of nociceptin on histamine and serotonin release in the central nervous system]. Acta pharmaceutica Hungarica. vol 76. issue 3. 2007-01-03. PMID:17094659. |
administered nc (5.5 nmol/rat) on histamine and serotonin levels in blood plasma, csf and brain areas (hypothalamus and hippocampus) was studies and compared to the effect of the mast cell degranulator compound 48/80(100microg/kg, i.c.v.) |
2007-01-03 |
2023-08-12 |
Not clear |
| Migiwa Komiya, Takashi Takeuchi, Etsumori Harad. Lemon oil vapor causes an anti-stress effect via modulating the 5-HT and DA activities in mice. Behavioural brain research. vol 172. issue 2. 2006-12-28. PMID:16780969. |
moreover, the lemon oil significantly accelerated the metabolic turnover of da in the hippocampus and of 5-ht in the prefrontal cortex and striatum. |
2006-12-28 |
2023-08-12 |
mouse |
| Hiroki Koizumi, Kenji Hashimoto, Masaomi Iy. Dietary restriction changes behaviours in brain-derived neurotrophic factor heterozygous mice: role of serotonergic system. The European journal of neuroscience. vol 24. issue 8. 2006-12-21. PMID:17074054. |
after carrying out a behavioural evaluation, we determined the bdnf mrna levels, as well as mrna levels for subtypes (5-ht(1a), 5-ht(1b), 5-ht(2a) and 5-ht(2c)) of the 5-ht receptor and 5-ht transporter (5-htt), protein levels of bdnf and concentrations of 5-ht and 5-hiaa in the hypothalamus, hippocampus and frontal cortex. |
2006-12-21 |
2023-08-12 |
mouse |
| Hiroki Koizumi, Kenji Hashimoto, Masaomi Iy. Dietary restriction changes behaviours in brain-derived neurotrophic factor heterozygous mice: role of serotonergic system. The European journal of neuroscience. vol 24. issue 8. 2006-12-21. PMID:17074054. |
the concentrations of 5-ht and 5-hiaa in the frontal cortex, and 5-ht in the hippocampus, of bdnf(+/-) mice were significantly lower than those of wild-type mice. |
2006-12-21 |
2023-08-12 |
mouse |
| A Dairam, E M Antunes, K S Saravanan, S Day. Non-steroidal anti-inflammatory agents, tolmetin and sulindac, inhibit liver tryptophan 2,3-dioxygenase activity and alter brain neurotransmitter levels. Life sciences. vol 79. issue 24. 2006-12-19. PMID:16952380. |
the results show that whilst tolmetin and sulindac increase serotonin levels in the hippocampus, these agents also significantly reduce dopamine levels in the striatum. |
2006-12-19 |
2023-08-12 |
rat |
| Rudolf N Cardina. Neural systems implicated in delayed and probabilistic reinforcement. Neural networks : the official journal of the International Neural Network Society. vol 19. issue 8. 2006-12-12. PMID:16938431. |
the contributions to delay and uncertainty discounting of neuromodulators including serotonin, dopamine, and noradrenaline, and of specific neural structures including the nucleus accumbens core, nucleus accumbens shell, orbitofrontal cortex, basolateral amygdala, anterior cingulate cortex, medial prefrontal (prelimbic/infralimbic) cortex, insula, subthalamic nucleus, and hippocampus are examined. |
2006-12-12 |
2023-08-12 |
Not clear |
| Mathew E Brevard, Jerrold S Meyer, Josie A Harder, Craig F Ferri. Imaging brain activity in conscious monkeys following oral MDMA ("ecstasy"). Magnetic resonance imaging. vol 24. issue 6. 2006-12-07. PMID:16824965. |
following mdma administration, the midbrain raphe nuclei and substantia nigra, major sources of serotonin and dopamine, were activated as were the hippocampus, hypothalamus and amygdala. |
2006-12-07 |
2023-08-12 |
monkey |
| Jacob P R Jacobsen, Arne Mør. Chronic corticosterone decreases brain-derived neurotrophic factor (BDNF) mRNA and protein in the hippocampus, but not in the frontal cortex, of the rat. Brain research. vol 1110. issue 1. 2006-12-06. PMID:16876769. |
in both the frontal cortex and hippocampus, tissue levels of 5-ht and 5-hiaa were increased and decreased, respectively. |
2006-12-06 |
2023-08-12 |
rat |
| Ravikumar Ponnusamy, Nithyananda Pradha. The effects of chronic administration of ethosuximide on learning and memory: a behavioral and biochemical study on nonepileptic rats. Behavioural pharmacology. vol 17. issue 7. 2006-12-06. PMID:17021389. |
high performance liquid chromatography with electrochemical detection was used for quantification of glutamate, glycine, taurine, gamma-aminobutyric acid, dopamine, and serotonin in the frontal cortex and hippocampus to elucidate the neurobiological basis of the effect of ethosuximide on learning and memory. |
2006-12-06 |
2023-08-12 |
rat |
| Turhan Canli, Maolin Qiu, Kazufumi Omura, Eliza Congdon, Brian W Haas, Zenab Amin, Martin J Herrmann, R Todd Constable, Klaus Peter Lesc. Neural correlates of epigenesis. Proceedings of the National Academy of Sciences of the United States of America. vol 103. issue 43. 2006-12-06. PMID:17032778. |
based on functional mri and perfusion data, we found support for a model by which life stress interacts with the effect of serotonin transporter genotype on amygdala and hippocampal resting activation, two regions involved in depression and stress. |
2006-12-06 |
2023-08-12 |
Not clear |
| Turhan Canli, Maolin Qiu, Kazufumi Omura, Eliza Congdon, Brian W Haas, Zenab Amin, Martin J Herrmann, R Todd Constable, Klaus Peter Lesc. Neural correlates of epigenesis. Proceedings of the National Academy of Sciences of the United States of America. vol 103. issue 43. 2006-12-06. PMID:17032778. |
life stress also differentially affected, as a function of serotonin transporter genotype, functional connectivity of the amygdala and hippocampus with a wide network of other regions, as well as gray matter structural features, and affected individuals' level of rumination. |
2006-12-06 |
2023-08-12 |
Not clear |
| Yotam Sagi, Noam Driguès, Moussa B H Youdi. The neurochemical and behavioral effects of the novel cholinesterase-monoamine oxidase inhibitor, ladostigil, in response to L-dopa and L-tryptophan, in rats. British journal of pharmacology. vol 146. issue 4. 2006-11-29. PMID:16086033. |
chronic treatment of rats with ladostigil (52 mg kg(-1) for 21 days) inhibited hippocampal and striatal mao a and b activities by >90%, increased striatal levels of dopamine and serotonin, and inhibited striatal che activity by approximately 50%. |
2006-11-29 |
2023-08-12 |
rat |
| Hiroyuki Toda, Go Suzuki, Masashi Nibuya, Katsutoshi Shioda, Koichi Nishijima, Tomoki Wakizono, Yasunari Kanda, Yasuhiro Watanabe, Kunio Shimizu, Soichiro Nomur. Behavioral stress and activated serotonergic neurotransmission induce XBP-1 splicing in the rat brain. Brain research. vol 1112. issue 1. 2006-11-28. PMID:16889758. |
in this study, we demonstrated that xbp-1 splicing is promptly induced in the rat brain including the hippocampus by both inescapable electric foot shock (is) and pharmacologically manipulated activation of 5-hydroxytryptamine release in a dose-dependent manner. |
2006-11-28 |
2023-08-12 |
rat |
| Esther O'Shea, Laura Orio, Isabel Escobedo, Veronica Sanchez, Jorge Camarero, Alfred Richard Green, Maria Isabel Colad. MDMA-induced neurotoxicity: long-term effects on 5-HT biosynthesis and the influence of ambient temperature. British journal of pharmacology. vol 148. issue 6. 2006-11-27. PMID:16770327. |
5-ht content and [3h]-paroxetine binding were measured in the cortex, hippocampus and striatum. |
2006-11-27 |
2023-08-12 |
rat |
| Esther O'Shea, Laura Orio, Isabel Escobedo, Veronica Sanchez, Jorge Camarero, Alfred Richard Green, Maria Isabel Colad. MDMA-induced neurotoxicity: long-term effects on 5-HT biosynthesis and the influence of ambient temperature. British journal of pharmacology. vol 148. issue 6. 2006-11-27. PMID:16770327. |
tissue 5-ht content and [3h]-paroxetine binding were reduced in the cortex (26-53%) and hippocampus (25-74%) at all time points (1, 2, 4, 8 and 32 weeks). |
2006-11-27 |
2023-08-12 |
rat |
| Jordi Camarasa, David Pubill, Elena Escubed. Association of caffeine to MDMA does not increase antinociception but potentiates adverse effects of this recreational drug. Brain research. vol 1111. issue 1. 2006-11-24. PMID:16889759. |
following administration of mdma to rats, there was a persistent decrease in the number of serotonin transporter sites in the cortex, striatum and hippocampus, which was potentiated by caffeine co-treatment. |
2006-11-24 |
2023-08-12 |
rat |
| Shuji Iritani, Mizuho Tohgi, Tetsuaki Arai, Kenji Iked. Immunohistochemical study of the serotonergic neuronal system in an animal model of the mood disorder. Experimental neurology. vol 201. issue 1. 2006-11-14. PMID:16677634. |
to elucidate these issues, we immunohistochemically examined vesicle monoamine transporter 2 (vmat2), serotonin receptor type 1a (5ht1a), and serotonin transporter (5htt) in the hippocampal region of reserpine-treated rats, an animal model of depression. |
2006-11-14 |
2023-08-12 |
rat |