| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| D P Figlewicz, P Szo. Insulin stimulates membrane phospholipid metabolism by enhancing endogenous alpha 1-adrenergic activity in the rat hippocampus. Brain research. vol 550. issue 1. 1991-10-17. PMID:1653632. |
in the present study, we tested whether insulin can stimulate membrane phospholipid metabolism in the rat hippocampus, a cns region in which insulin has been reported to stimulate the phosphorylation of a pkc substrate protein and to suppress spontaneous electrical activity of pyramidal cells. |
1991-10-17 |
2023-08-11 |
rat |
| D P Figlewicz, P Szo. Insulin stimulates membrane phospholipid metabolism by enhancing endogenous alpha 1-adrenergic activity in the rat hippocampus. Brain research. vol 550. issue 1. 1991-10-17. PMID:1653632. |
these compounds blocked insulin stimulation of ip1 accumulation, suggesting that the action of insulin to stimulate pi turnover is secondary to enhancement of endogenous noradrenergic activity within the hippocampus. |
1991-10-17 |
2023-08-11 |
rat |
| D P Figlewicz, P Szo. Insulin stimulates membrane phospholipid metabolism by enhancing endogenous alpha 1-adrenergic activity in the rat hippocampus. Brain research. vol 550. issue 1. 1991-10-17. PMID:1653632. |
significant (p less than 0.05) increases of hippocampal diacylglycerol (a product of phosphoinositol hydrolysis) content were observed at 1, 5 or 10 min of incubation with 50 or 100 nm insulin. |
1991-10-17 |
2023-08-11 |
rat |
| E Z Tchilian, I E Zhelezarov, V V Petkov, C I Hadjiivanov. 125I-insulin binding is decreased in olfactory bulbs of aged rats. Neuropeptides. vol 17. issue 4. 1991-06-17. PMID:2093152. |
in the aged rats the specific insulin binding was not changed in the frontal cortex, hippocampus and hypothalamus as compared to the young ones. |
1991-06-17 |
2023-08-11 |
rat |
| E Z Tchilian, I E Zhelezarov, V V Petkov, C I Hadjiivanov. 125I-insulin binding is decreased in olfactory bulbs of aged rats. Neuropeptides. vol 17. issue 4. 1991-06-17. PMID:2093152. |
in the young animals the highest level of specific insulin binding was found in the olfactory bulb, with lower values of specific insulin binding in the frontal cortex, hippocampus and hypothalamus. |
1991-06-17 |
2023-08-11 |
rat |
| M W Schwartz, J L Marks, A J Sipols, D G Baskin, S C Woods, S E Kahn, D Port. Central insulin administration reduces neuropeptide Y mRNA expression in the arcuate nucleus of food-deprived lean (Fa/Fa) but not obese (fa/fa) Zucker rats. Endocrinology. vol 128. issue 5. 1991-05-24. PMID:2019270. |
central insulin significantly reduced the area of hybridization in the arc (0.235 +/- 0.017 mm2; mean +/- se) compared to vehicle-treated controls (0.331 +/- 0.037 mm2; p less than 0.05), but was without effect in the hippocampus. |
1991-05-24 |
2023-08-11 |
rat |
| C L Voll, R N Aue. Postischemic seizures and necrotizing ischemic brain damage: neuroprotective effect of postischemic diazepam and insulin. Neurology. vol 41. issue 3. 1991-04-25. PMID:2006013. |
however, the combination of diazepam plus insulin yielded the greatest proportion of undamaged brains in the hippocampus, thalamus, and midbrain. |
1991-04-25 |
2023-08-11 |
rat |
| D Figlewicz, P Szot, M R Greenwoo. Insulin stimulates inositol incorporation in hippocampus of lean but not obese Zucker rats. Physiology & behavior. vol 47. issue 2. 1990-06-05. PMID:2159162. |
smaller but significant stimulations were observed in the fa/fa zucker rat (n = 5) hippocampus [10 +/- 3 and 13 +/- 4% stimulation over control levels (inositol phosphates) and 10 +/- 4 and 14 +/- 3% stimulation over control levels (inositol lipids) with 1 and 5 nm insulin]. |
1990-06-05 |
2023-08-11 |
rat |
| D Figlewicz, P Szot, M R Greenwoo. Insulin stimulates inositol incorporation in hippocampus of lean but not obese Zucker rats. Physiology & behavior. vol 47. issue 2. 1990-06-05. PMID:2159162. |
insulin stimulates inositol incorporation in hippocampus of lean but not obese zucker rats. |
1990-06-05 |
2023-08-11 |
rat |
| D Figlewicz, P Szot, M R Greenwoo. Insulin stimulates inositol incorporation in hippocampus of lean but not obese Zucker rats. Physiology & behavior. vol 47. issue 2. 1990-06-05. PMID:2159162. |
no difference in insulin binding to hippocampal membranes was observed among the three genotypes. |
1990-06-05 |
2023-08-11 |
rat |
| D Figlewicz, P Szot, M R Greenwoo. Insulin stimulates inositol incorporation in hippocampus of lean but not obese Zucker rats. Physiology & behavior. vol 47. issue 2. 1990-06-05. PMID:2159162. |
in the present study, we report that insulin at concentrations of 1 and 5 nm significantly stimulates incorporation of 3h-myoinositol into inositol phosphates (29 +/- 5% and 20 +/- 6% stimulation over control levels) and membrane inositol lipids (29 +/- 4% and 20 +/- 6% stimulation over control levels) within hippocampal slices from lean (fa/fa) zucker rats (n = 3 preparations). |
1990-06-05 |
2023-08-11 |
rat |
| D Figlewicz, P Szot, M R Greenwoo. Insulin stimulates inositol incorporation in hippocampus of lean but not obese Zucker rats. Physiology & behavior. vol 47. issue 2. 1990-06-05. PMID:2159162. |
insulin had no effect on 3h-inositol incorporation into hippocampal slices from obese (fa/fa) zucker rats (n = 5). |
1990-06-05 |
2023-08-11 |
rat |
| L Bassas, M Girbau, M A Lesniak, J Roth, F de Pabl. Development of receptors for insulin and insulin-like growth factor-I in head and brain of chick embryos: autoradiographic localization. Endocrinology. vol 125. issue 5. 1989-11-22. PMID:2551646. |
in older embryos, as in the adult brain, insulin binding was high in the paleostriatum augmentatum and molecular layer of the cerebellum, while igf-i binding was prominent in the hippocampus and neostriatum. |
1989-11-22 |
2023-08-11 |
chicken |
| J L Blair, D S Warner, M M Tod. Effects of elevated plasma magnesium versus calcium on cerebral ischemic injury in rats. Stroke. vol 20. issue 4. 1989-05-10. PMID:2648653. |
in the hippocampus, mgcl2 + insulin resulted in 66 +/- 6% (mean +/- sd) dead ca1 pyramidal cells, which was similar to the amount in saline-treated rats (68 +/- 10%). |
1989-05-10 |
2023-08-11 |
rat |
| Z Merali, Q Ahmad, J Veitc. Behavioral and neurochemical profile of the spontaneously diabetic Wistar BB rat. Behavioural brain research. vol 29. issue 1-2. 1988-09-12. PMID:2900015. |
however, the cessation of insulin administration to the sdr for 4 days resulted in significant increases in the levels of norepinephrine in the cortex and the hypothalamus, da in the hippocampus, and homovanillic acid in the striatum. |
1988-09-12 |
2023-08-11 |
rat |
| K Seto, H Saito, Y Takeshima, K Kitaoka, Y Sasaki, F Kimura, T Tsuda, M Kawakam. Influence of microinjection of insulin into hippocampus on hepatic acetate metabolism in rabbits. Experimental and clinical endocrinology. vol 87. issue 3. 1987-01-02. PMID:3536539. |
influence of microinjection of insulin into hippocampus on hepatic acetate metabolism in rabbits. |
1987-01-02 |
2023-08-11 |
Not clear |
| K Seto, H Saito, Y Takeshima, K Kitaoka, Y Sasaki, F Kimura, T Tsuda, M Kawakam. Influence of microinjection of insulin into hippocampus on hepatic acetate metabolism in rabbits. Experimental and clinical endocrinology. vol 87. issue 3. 1987-01-02. PMID:3536539. |
insulin was injected directly into the dorsal hippocampus (dhpc) of rabbits, and changes in hepatic acetate metabolism were studied. |
1987-01-02 |
2023-08-11 |
Not clear |
| R P Simon, J W Schmidley, J H Swan, B S Meldru. Neuronal alterations in hippocampus following severe hypoglycaemia: a light microscopic and ultrastructural study in the rat. Neuropathology and applied neurobiology. vol 12. issue 1. 1986-06-03. PMID:3703153. |
we therefore studied the selectively vulnerable neurons of rat hippocampus by light and electron microscopy (including the pyroantimonate technique) following 30 and 60 min of eeg isoelectricity resulting from insulin hypoglycaemia. |
1986-06-03 |
2023-08-11 |
rat |
| D G Baskin, L J Stein, H Ikeda, S C Woods, D P Figlewicz, D Porte, M R Greenwood, D M Dors. Genetically obese Zucker rats have abnormally low brain insulin content. Life sciences. vol 36. issue 7. 1985-03-18. PMID:3881641. |
the concentration of immunoreactive insulin (iri) extracted from the olfactory bulb, hypothalamus, hippocampus, cerebral cortex, amygdala, midbrain, and hindbrain was significantly lower in obese (fa/fa) and heterozygous (fa/fa) zucker rats in comparison to lean (fa/fa) zucker rats. |
1985-03-18 |
2023-08-11 |
rat |
| R A Palovcik, M I Phillips, M S Kappy, M K Raizad. Insulin inhibits pyramidal neurons in hippocampal slices. Brain research. vol 309. issue 1. 1984-12-12. PMID:6386100. |
insulin inhibits pyramidal neurons in hippocampal slices. |
1984-12-12 |
2023-08-12 |
rat |