All Relations between hippocampus and glutamate

Publication Sentence Publish Date Extraction Date Species
Matthijs G Bossong, Robin Wilson, Elizabeth Appiah-Kusi, Philip McGuire, Sagnik Bhattacharyy. Human Striatal Response to Reward Anticipation Linked to Hippocampal Glutamate Levels. The international journal of neuropsychopharmacology. vol 21. issue 7. 2019-07-17. PMID:29444252. human striatal response to reward anticipation linked to hippocampal glutamate levels. 2019-07-17 2023-08-13 human
Matthijs G Bossong, Robin Wilson, Elizabeth Appiah-Kusi, Philip McGuire, Sagnik Bhattacharyy. Human Striatal Response to Reward Anticipation Linked to Hippocampal Glutamate Levels. The international journal of neuropsychopharmacology. vol 21. issue 7. 2019-07-17. PMID:29444252. however, in humans the association between reward-related ventral striatal response and hippocampal glutamate levels is unclear. 2019-07-17 2023-08-13 human
J Prius-Mengual, M Pérez-Rodríguez, Y Andrade-Talavera, A Rodríguez-Moren. NMDA Receptors Containing GluN2B/2C/2D Subunits Mediate an Increase in Glutamate Release at Hippocampal CA3-CA1 Synapses. Molecular neurobiology. vol 56. issue 3. 2019-07-17. PMID:29916144. nmda receptors containing glun2b/2c/2d subunits mediate an increase in glutamate release at hippocampal ca3-ca1 synapses. 2019-07-17 2023-08-13 Not clear
J Prius-Mengual, M Pérez-Rodríguez, Y Andrade-Talavera, A Rodríguez-Moren. NMDA Receptors Containing GluN2B/2C/2D Subunits Mediate an Increase in Glutamate Release at Hippocampal CA3-CA1 Synapses. Molecular neurobiology. vol 56. issue 3. 2019-07-17. PMID:29916144. here, we studied whether non-postsynaptic nmdars, putatively presynaptic (prenmdars), are tonically active at hippocampal ca3-ca1 synapses, and if they modulate glutamate release. 2019-07-17 2023-08-13 Not clear
Saiqa Tabassum, Saara Ahmad, Syeda Madiha, Saima Khaliq, Sidrah Shahzad, Zehra Batool, Saida Haide. Impact of oral supplementation of Glutamate and GABA on memory performance and neurochemical profile in hippocampus of rats. Pakistan journal of pharmaceutical sciences. vol 30. issue 3(Suppl.). 2019-07-09. PMID:28655701. impact of oral supplementation of glutamate and gaba on memory performance and neurochemical profile in hippocampus of rats. 2019-07-09 2023-08-13 rat
Natalie L Voets, Carl J Hodgetts, Arjune Sen, Jane E Adcock, Uzay Emi. Hippocampal MRS and subfield volumetry at 7T detects dysfunction not specific to seizure focus. Scientific reports. vol 7. issue 1. 2019-07-08. PMID:29170537. hippocampal metabolite spectra were acquired to determine absolute concentrations of glutamate, glutamine, myo-inositol, naa, creatine and choline. 2019-07-08 2023-08-13 human
Natalie R S Goldberg, Samuel E Marsh, Joseph Ochaba, Brandon C Shelley, Hayk Davtyan, Leslie M Thompson, Joan S Steffan, Clive N Svendsen, Mathew Blurton-Jone. Human Neural Progenitor Transplantation Rescues Behavior and Reduces α-Synuclein in a Transgenic Model of Dementia with Lewy Bodies. Stem cells translational medicine. vol 6. issue 6. 2019-06-27. PMID:28225193. within this diverse group, dementia with lewy bodies (dlb) is characterized by the aberrant accumulation of α-syn in cortical, hippocampal, and brainstem neurons, resulting in multiple cellular stressors that particularly impair dopamine and glutamate neurotransmission and related motor and cognitive function. 2019-06-27 2023-08-13 human
A Ortiz-Pérez, O Limón-Morales, J C Rojas-Castañeda, M Cerbón, O Picaz. Prolactin prevents the kainic acid-induced neuronal loss in the rat hippocampus by inducing prolactin receptor and putatively increasing the VGLUT1 overexpression. Neuroscience letters. vol 694. 2019-06-21. PMID:30500398. here, we investigated if a daily prl dose of 100 μg or vehicle for 14 days in ovariectomized rats (ovx) prevents neuron loss induced by ka administered on the third day of prl treatment in a systemic single dose of 7.5 mg/kg or vehicle, and promotes prl-r, vesicular glutamate transporter 1 (vglut1) and glutamic acid decarboxylase 65 (gad65) expression changes in the hippocampus of sacrificed rats 27 days after the ka administration. 2019-06-21 2023-08-13 rat
Sharon S Lander, Usman Khan, Nicole Lewandowski, Darpan Chakraborty, Frank A Provenzano, Susana Mingote, Sergiy Chornyy, Francesca Frigerio, Pierre Maechler, Hanoch Kaphzan, Scott A Small, Stephen Rayport, Inna Gaisler-Salomo. Glutamate Dehydrogenase-Deficient Mice Display Schizophrenia-Like Behavioral Abnormalities and CA1-Specific Hippocampal Dysfunction. Schizophrenia bulletin. vol 45. issue 1. 2019-06-19. PMID:29471549. glutamate dehydrogenase-deficient mice display schizophrenia-like behavioral abnormalities and ca1-specific hippocampal dysfunction. 2019-06-19 2023-08-13 mouse
Sharon S Lander, Usman Khan, Nicole Lewandowski, Darpan Chakraborty, Frank A Provenzano, Susana Mingote, Sergiy Chornyy, Francesca Frigerio, Pierre Maechler, Hanoch Kaphzan, Scott A Small, Stephen Rayport, Inna Gaisler-Salomo. Glutamate Dehydrogenase-Deficient Mice Display Schizophrenia-Like Behavioral Abnormalities and CA1-Specific Hippocampal Dysfunction. Schizophrenia bulletin. vol 45. issue 1. 2019-06-19. PMID:29471549. brain imaging has revealed that the ca1 subregion of the hippocampus is hyperactive in prodromal and diagnosed patients with schizophrenia (scz), and that glutamate is a driver of this hyperactivity. 2019-06-19 2023-08-13 mouse
Sharon S Lander, Usman Khan, Nicole Lewandowski, Darpan Chakraborty, Frank A Provenzano, Susana Mingote, Sergiy Chornyy, Francesca Frigerio, Pierre Maechler, Hanoch Kaphzan, Scott A Small, Stephen Rayport, Inna Gaisler-Salomo. Glutamate Dehydrogenase-Deficient Mice Display Schizophrenia-Like Behavioral Abnormalities and CA1-Specific Hippocampal Dysfunction. Schizophrenia bulletin. vol 45. issue 1. 2019-06-19. PMID:29471549. parameters of hippocampal synaptic function revealed excess glutamate release and an elevated excitatory/inhibitory balance in ca1. 2019-06-19 2023-08-13 mouse
Sharon S Lander, Usman Khan, Nicole Lewandowski, Darpan Chakraborty, Frank A Provenzano, Susana Mingote, Sergiy Chornyy, Francesca Frigerio, Pierre Maechler, Hanoch Kaphzan, Scott A Small, Stephen Rayport, Inna Gaisler-Salomo. Glutamate Dehydrogenase-Deficient Mice Display Schizophrenia-Like Behavioral Abnormalities and CA1-Specific Hippocampal Dysfunction. Schizophrenia bulletin. vol 45. issue 1. 2019-06-19. PMID:29471549. these findings advance glud1 deficiency as a driver of excess hippocampal excitatory transmission and scz symptoms, and identify gdh as a target for glutamate modulation pharmacotherapy for scz. 2019-06-19 2023-08-13 mouse
Y M Geng, J T Xue, J P Su, H Y L. Molecular mechanism of action of valproate acid alone or in combination with chlorpromazine in the epigenetic regulation of schizophrenia. Journal of biological regulators and homeostatic agents. vol 32. issue 6. 2019-06-14. PMID:30574748. the real time pcr assay was used to detect the mrna expression changes of gaba system gene [gabbr1 (gaba b receptor 1)], gad1 (glutamic acid decarboxylase1), gad2 (glutamic acid decarboxylase2), lipase metabolic key enzyme lpl (lipoprotein lipase) gene, glutamate neurotransmitter gene gria2 (ampa subtype glutamate receptors 2), inward rectifier potassium channel members kcnj4 (potassium voltage-gated channel subfamily j member 4) and neuropeptide signal gene tac1 (tachykinin precursor 1,tac1) in four brain regions: the prefrontal cortex (pc), the amygdala (am), the caudate-putamen (cpu) and the hippocampus (hip). 2019-06-14 2023-08-13 rat
Zhiling Guo, Yiu Chung Tse, Ying Zhang, Qiang Sun, Haley A Vecchiarelli, Robert Aukema, Matthew N Hill, Tak Pan Wong, Patricia Boks. Prenatal immune activation potentiates endocannabinoid-related plasticity of inhibitory synapses in the hippocampus of adolescent rat offspring. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 28. issue 12. 2019-06-12. PMID:30257799. we compared two forms of ecb-related plasticity of evoked inhibitory postsynaptic currents, namely depolarization-induced suppression of inhibition (dsi) and metabotropic glutamate receptor-induced long term depression (mglur-iltd), in both the dorsal and ventral hippocampus between adolescent offspring from rat dams that received either saline or bacterial lipopolysaccharide (lps) during pregnancy. 2019-06-12 2023-08-13 rat
Ghallab Alotaibi, Shafiqur Rahma. Effects of glial glutamate transporter activator in formalin-induced pain behaviour in mice. European journal of pain (London, England). vol 23. issue 4. 2019-06-12. PMID:30427564. previous studies have shown that astroglial glutamate transporter-1 (glt-1) in the hippocampus and anterior cingulate cortex (acc) is critically involved in pain processing and modulation. 2019-06-12 2023-08-13 mouse
Junhua Li, Minyan Guo, Yafang Liu, Guiyun Wu, Liping Miao, Jing Zhang, Zhiyi Zuo, Yujuan L. Both GSK-3β/CRMP2 and CDK5/CRMP2 pathways participate in the protection of dexmedetomidine against propofol-induced learning and memory impairment in neonatal rats. Toxicological sciences : an official journal of the Society of Toxicology. 2019-06-12. PMID:31187143. propofol induced apoptosis in the hippocampal neurons and astrocytes, inhibited neuronal proliferation in the dg region, down-regulated the level of γ-aminobutyric acid (gaba) and glutamate in the hippocampus, and impaired long-term cognitive function. 2019-06-12 2023-08-13 rat
Shlomo Sragovich, Anna Malishkevich, Yael Piontkewitz, Eliezer Giladi, Olga Touloumi, Roza Lagoudaki, Nikolaos Grigoriadis, Illana Goze. The autism/neuroprotection-linked ADNP/NAP regulate the excitatory glutamatergic synapse. Translational psychiatry. vol 9. issue 1. 2019-06-10. PMID:30664622. significant effects on hippocampal and cerebral cortical expression of the presynaptic slc17a7 gene encoding vesicular excitatory glutamate transporter 1 (vglut1) were observed at the rna and immunohistochemical levels, explaining the dti results. 2019-06-10 2023-08-13 mouse
András Mihál. The Reactive Plasticity of Hippocampal Ionotropic Glutamate Receptors in Animal Epilepsies. International journal of molecular sciences. vol 20. issue 5. 2019-06-07. PMID:30818767. the reactive plasticity of hippocampal ionotropic glutamate receptors in animal epilepsies. 2019-06-07 2023-08-13 Not clear
Mariline M Silva, Beatriz Rodrigues, Joana Fernandes, Sandra D Santos, Laura Carreto, Manuel A S Santos, Paulo Pinheiro, Ana Luísa Carvalh. MicroRNA-186-5p controls GluA2 surface expression and synaptic scaling in hippocampal neurons. Proceedings of the National Academy of Sciences of the United States of America. vol 116. issue 12. 2019-05-31. PMID:30808806. here, we report that chronic blockade of glutamate receptors of the ampa and nmda types in hippocampal neurons in culture induces changes in the neuronal mrna and mirna transcriptomes, leading to synaptic upscaling. 2019-05-31 2023-08-13 Not clear
Sean M Mooney-Leber, Stephanie S Spielmann, Susanne Brummelt. Repetitive neonatal pain and reduced maternal care alter brain neurochemistry. Developmental psychobiology. vol 60. issue 8. 2019-05-29. PMID:30288732. we found that exposure to maternal isolation and neonatal pain produced an increase in serum corticosterone but decreased glutamate levels in the hippocampus and frontal cortex. 2019-05-29 2023-08-13 rat