| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Adam Wojtas, Agnieszka Bysiek, Agnieszka Wawrzczak-Bargiela, Marzena Maćkowiak, Krystyna Gołembiowsk. Limbic System Response to Psilocybin and Ketamine Administration in Rats: A Neurochemical and Behavioral Study. International journal of molecular sciences. vol 25. issue 1. 2024-01-11. PMID:38203271. |
both drugs influenced glutamate and gaba release in the nucleus accumbens, hippocampus and amygdala and increased ach levels in the hippocampus. |
2024-01-11 |
2024-01-13 |
rat |
| Xing Ye, Jun-Yi Lin, Ling-Xia Chen, Xue-Chun Wu, Kai-Jun Ma, Bei-Xu Li, You-Xin Fan. SREBP1 deficiency diminishes glutamate-mediated HT22 cell damage and hippocampal neuronal pyroptosis induced by status epilepticus. Heliyon. vol 10. issue 1. 2024-01-11. PMID:38205297. |
additionally, we treated ht22 hippocampal cells with glutamate to create neuronal injury models in vitro. |
2024-01-11 |
2024-01-13 |
rat |
| Xiaonan Wang, Fuping Zhang, Le Niu, Junni Yan, Huanhuan Liu, Di Wang, Juan Hui, Haiyue Dai, Jinggui Song, Zhaohui Zhan. High-frequency repetitive transcranial magnetic stimulation improves depressive-like behaviors in CUMS-induced rats by modulating astrocyte GLT-1 to reduce glutamate toxicity. Journal of affective disorders. 2023-12-30. PMID:38159655. |
and rtms intervention reversed the elevated glutamate concentration in the hippocampus of cums rats using an elisa kit. |
2023-12-30 |
2024-01-05 |
rat |
| Wenxue Liu, Min Jia, Keyin Zhang, Jiang Chen, Xiyu Zhu, Ruisha Li, Zhenjun Xu, Yanyu Zang, Yapeng Wang, Jun Pan, Daqing Ma, Jianjun Yang, Dongjin Wan. Increased A1 astrocyte activation-driven hippocampal neural network abnormality mediates delirium-like behavior in aged mice undergoing cardiac surgery. Aging cell. 2023-12-29. PMID:38155547. |
the high neuroinflammatory state induced by surgery resulted in glutamate accumulation in the extrasynaptic space, which subsequently decreased the excitability of pyramidal neurons and increased the pv interneurons inhibition through enhancing n-methyl-d-aspartate receptors' tonic currents in the hippocampus. |
2023-12-29 |
2023-12-31 |
mouse |
| Xiang Wu, Jian Liu, Yanping Hui, Zhongheng Wu, Ling Wang, Yixuan Wang, Yihua Bai, Jing Li, Lei Zhang, Yue Xi, Qiaojun Zhang, Libo L. Long-term intermittent theta burst stimulation enhanced hippocampus-dependent memory by regulating hippocampal theta oscillation and neurotransmitter levels in healthy rats. Neurochemistry international. 2023-12-29. PMID:38157888. |
however, it remains largely unknown whether this effect is achieved by regulating hippocampal theta oscillation and neurotransmitters gamma-aminobutyric acid (gaba) and glutamate, which are strongly related to memory. |
2023-12-29 |
2024-01-05 |
rat |
| Xiang Wu, Jian Liu, Yanping Hui, Zhongheng Wu, Ling Wang, Yixuan Wang, Yihua Bai, Jing Li, Lei Zhang, Yue Xi, Qiaojun Zhang, Libo L. Long-term intermittent theta burst stimulation enhanced hippocampus-dependent memory by regulating hippocampal theta oscillation and neurotransmitter levels in healthy rats. Neurochemistry international. 2023-12-29. PMID:38157888. |
thus, we investigated the effect of 14 days of itbs on hippocampus-dependent memory and further explored the roles of hippocampal theta oscillation and neurotransmitters gaba and glutamate in this effect. |
2023-12-29 |
2024-01-05 |
rat |
| Katia Cortese, Maria Cristina Gagliani, Luca Raiter. Interactions between Glycine and Glutamate through Activation of Their Transporters in Hippocampal Nerve Terminals. Biomedicines. vol 11. issue 12. 2023-12-23. PMID:38137373. |
interactions between glycine and glutamate through activation of their transporters in hippocampal nerve terminals. |
2023-12-23 |
2023-12-25 |
mouse |
| Katia Cortese, Maria Cristina Gagliani, Luca Raiter. Interactions between Glycine and Glutamate through Activation of Their Transporters in Hippocampal Nerve Terminals. Biomedicines. vol 11. issue 12. 2023-12-23. PMID:38137373. |
evidence supports the pathophysiological relevance of crosstalk between the neurotransmitters glycine and glutamate and their close interactions; some reports even support the possibility of glycine-glutamate cotransmission in central nervous system (cns) areas, including the hippocampus. |
2023-12-23 |
2023-12-25 |
mouse |
| Katia Cortese, Maria Cristina Gagliani, Luca Raiter. Interactions between Glycine and Glutamate through Activation of Their Transporters in Hippocampal Nerve Terminals. Biomedicines. vol 11. issue 12. 2023-12-23. PMID:38137373. |
our main aims here were: (i) to investigate release-regulating, transporter-mediated interactions between glycine and glutamate in hippocampal nerve terminals and (ii) to determine the coexistence of transporters for glycine and glutamate in these terminals. |
2023-12-23 |
2023-12-25 |
mouse |
| b' Andrijana Stanisavljevi\\xc4\\x87 Ili\\xc4\\x87, Sne\\xc5\\xbeana \\xc4\\x90or\\xc4\\x91evi\\xc4\\x87, Drago\\xc5\\xa1 Inta, Stefan Borgwardt, Dragana Filipovi\\xc4\\x8. Olanzapine Effects on Parvalbumin/GAD67 Cell Numbers in Layers/Subregions of Dorsal Hippocampus of Chronically Socially Isolated Rats. International journal of molecular sciences. vol 24. issue 24. 2023-12-23. PMID:38139008.' |
we determined the effect of olz on pv-positive (+) and glutamate decarboxylase 67 (gad67) + cell numbers in the layers of dorsal hippocampus (dhipp) cornu ammonis (ca1-ca3) and dentate gyrus (dg) subregions in rats exposed to chronic social isolation (csis), which is an animal model of depression. |
2023-12-23 |
2023-12-25 |
rat |
| María Sancho-Alonso, Yaiza M Arenas, Paula Izquierdo-Altarejos, Mar Martinez-Garcia, Marta Llansola, Vicente Felip. Enhanced Activation of the S1PR2-IL-1β-Src-BDNF-TrkB Pathway Mediates Neuroinflammation in the Hippocampus and Cognitive Impairment in Hyperammonemic Rats. International journal of molecular sciences. vol 24. issue 24. 2023-12-23. PMID:38139078. |
the signaling pathways inducing neuroinflammation and altered glutamate receptors were analyzed in hippocampal slices. |
2023-12-23 |
2023-12-25 |
rat |
| Cristina Lao-Peregrin, Guoqing Xiang, Jihye Kim, Ipsit Srivastava, Alexandra B Fall, Danielle M Gerhard, Piia Kohtala, Daegeon Kim, Minseok Song, Mikel Garcia-Marcos, Joshua Levitz, Francis S Le. Synaptic plasticity via receptor tyrosine kinase/G-protein-coupled receptor crosstalk. Cell reports. vol 43. issue 1. 2023-12-20. PMID:38117654. |
we find that the receptor tyrosine kinase (rtk) trkb and the g-protein-coupled receptor (gpcr) metabotropic glutamate receptor 5 (mglur5) together mediate hippocampal synaptic plasticity in response to brain-derived neurotrophic factor (bdnf). |
2023-12-20 |
2023-12-23 |
Not clear |
| Hong-Kun Wang, Jin-Ming He, Yue-Heng Yan, Zi-Hao Wang, Ruo-Xuan Li, Yan-Yan Wan. [Effect of Suanzaoren Decoction on expression of ionotropic glutamate receptors and synaptic plasticity in hippocampus of anxiety rats]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 48. issue 20. 2023-12-19. PMID:38114151. |
[effect of suanzaoren decoction on expression of ionotropic glutamate receptors and synaptic plasticity in hippocampus of anxiety rats]. |
2023-12-19 |
2023-12-23 |
mouse |
| Hong-Kun Wang, Jin-Ming He, Yue-Heng Yan, Zi-Hao Wang, Ruo-Xuan Li, Yan-Yan Wan. [Effect of Suanzaoren Decoction on expression of ionotropic glutamate receptors and synaptic plasticity in hippocampus of anxiety rats]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 48. issue 20. 2023-12-19. PMID:38114151. |
enzyme-linked immunosorbent assay(elisa) was used to measure the levels of glutamate(glu) and γ-aminobutyric acid(gaba) in the rat hippocampus. |
2023-12-19 |
2023-12-23 |
mouse |
| Hong-Kun Wang, Jin-Ming He, Yue-Heng Yan, Zi-Hao Wang, Ruo-Xuan Li, Yan-Yan Wan. [Effect of Suanzaoren Decoction on expression of ionotropic glutamate receptors and synaptic plasticity in hippocampus of anxiety rats]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 48. issue 20. 2023-12-19. PMID:38114151. |
real-time fluorescence quantitative pcr(qrt-pcr) and western blot were employed to assess the gene and protein expression of ionotropic glutamate receptors in the hippocampal region. |
2023-12-19 |
2023-12-23 |
mouse |
| Ping Li, Yang Liu, Man-Shu Zou, Ting-Ting Wang, Hai-Peng Guo, Ting-Ting Ren, Ying He, Hua Wang, Yu-Hong Wan. [Neuroprotective effect and mechanism of Zuogui Jiangtang Jieyu Formula on diabetes mellitus complicated with depression model rats based on CX3CL1-CX3CR1 axis]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 48. issue 21. 2023-12-19. PMID:38114178. |
western blot was used to measure the expression levels of cx3cl1, cx3cr1, a2a adenosine receptor(a2ar), glutamate receptor 2a(nr2a), glutamate receptor 2b(nr2b), and brain-derived neurotrophic factor(bdnf) in the hippocampus. |
2023-12-19 |
2023-12-23 |
rat |
| Sung M Yang, Ayan Ghoshal, Jeffrey M Hubbard, Florian Gackière, Romain Teyssié, Stuart A Neale, Seth C Hopkins, Kenneth S Koblan, Linda J Bristow, Nina Dedi. TAAR1 agonist ulotaront modulates striatal and hippocampal glutamate function in a state-dependent manner. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2023-12-19. PMID:38110609. |
taar1 agonist ulotaront modulates striatal and hippocampal glutamate function in a state-dependent manner. |
2023-12-19 |
2023-12-21 |
mouse |
| Sung M Yang, Ayan Ghoshal, Jeffrey M Hubbard, Florian Gackière, Romain Teyssié, Stuart A Neale, Seth C Hopkins, Kenneth S Koblan, Linda J Bristow, Nina Dedi. TAAR1 agonist ulotaront modulates striatal and hippocampal glutamate function in a state-dependent manner. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2023-12-19. PMID:38110609. |
here we assessed the impact of ulotaront (sep-363856), a taar1 agonist in phase iii clinical development for schizophrenia, on glutamate function in the mouse striatum and hippocampus. |
2023-12-19 |
2023-12-21 |
mouse |
| Megha Kumari, Yasha Hasija, Richa Trived. Acute and sub-acute metabolic change in different brain regions induced by moderate blunt traumatic brain injury. Neuroreport. 2023-12-08. PMID:38064354. |
changes in myo-inositol, creatine, glutamate, succinate, lactate, and n-acetyl aspartic acid in hippocampal tissues were observed at day 3 pi. |
2023-12-08 |
2023-12-17 |
rat |
| Zhen Zeng, Jing He, Tao Ya. Characteristic early changes of Glu and Cho in brain regions affected by different types of subjective cognitive decline and their clinical significance. Medicine. vol 102. issue 49. 2023-12-08. PMID:38065860. |
using the bilateral hippocampus, left posterior cingulate gyrus (pcg), and frontal lobe as regions of interest, the scope under the peak of n-acetylaspartate (naa), choline complex (cho), glutamate (glu), metabolic images (mi), and creatine (cr) was tested. |
2023-12-08 |
2023-12-17 |
human |