| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Cheng Wei Lu, Tzu Yu Lin, Su Jane Wan. 11-Keto-β-Boswellic Acid Attenuates Glutamate Release and Kainic Acid-Induced Excitotoxicity in the Rat Hippocampus. Planta medica. vol 86. issue 6. 2020-04-16. PMID:32097973. |
11-keto-β-boswellic acid attenuates glutamate release and kainic acid-induced excitotoxicity in the rat hippocampus. |
2020-04-16 |
2023-08-13 |
rat |
| Peng Zheng, Benhua Zeng, Meiling Liu, Jianjun Chen, Junxi Pan, Yu Han, Yiyun Liu, Ke Cheng, Chanjuan Zhou, Haiyang Wang, Xinyu Zhou, Siwen Gui, Seth W Perry, Ma-Li Wong, Julio Licinio, Hong Wei, Peng Xi. The gut microbiome from patients with schizophrenia modulates the glutamate-glutamine-GABA cycle and schizophrenia-relevant behaviors in mice. Science advances. vol 5. issue 2. 2020-04-10. PMID:30775438. |
compared to hcs, germ-free mice receiving scz microbiome fecal transplants had lower glutamate and higher glutamine and gaba in the hippocampus and displayed scz-relevant behaviors similar to other mouse models of scz involving glutamatergic hypofunction. |
2020-04-10 |
2023-08-13 |
mouse |
| Daniel Ziemens, Franziska Oschmann, Niklas J Gerkau, Christine R Ros. Heterogeneity of Activity-Induced Sodium Transients between Astrocytes of the Mouse Hippocampus and Neocortex: Mechanisms and Consequences. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 39. issue 14. 2020-04-03. PMID:30737311. |
astrocytes of the neocortex, as opposed to the hippocampus proper, also express ionotropic glutamate receptors, which might provide additional sodium influx. |
2020-04-03 |
2023-08-13 |
mouse |
| Daniel Ziemens, Franziska Oschmann, Niklas J Gerkau, Christine R Ros. Heterogeneity of Activity-Induced Sodium Transients between Astrocytes of the Mouse Hippocampus and Neocortex: Mechanisms and Consequences. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 39. issue 14. 2020-04-03. PMID:30737311. |
stimulation of glutamatergic afferents or glutamate application induced sodium transients that were twice as large in neocortical as in hippocampal astrocytes, despite similar neuronal responses. |
2020-04-03 |
2023-08-13 |
mouse |
| Daria S Kalinina, Dmitrii S Vasilev, Anna B Volnova, Natalia N Nalivaeva, Igor A Zhuravi. Age-Dependent Electrocorticogram Dynamics and Epileptogenic Responsiveness in Rats Subjected to Prenatal Hypoxia. Developmental neuroscience. vol 41. issue 1-2. 2020-03-30. PMID:30904914. |
analyzing protein levels of neurotransmitter transporters in the brain structures of the hx rats, we found that the content of the glutamate transporter eaat1 was higher in the parietal cortex in all age groups of hx rats while in the hippocampus it decreased during postnatal development compared to controls. |
2020-03-30 |
2023-08-13 |
rat |
| Sarah R Metzbower, Yuyoung Joo, David R Benavides, Thomas A Blanpie. Properties of Individual Hippocampal Synapses Influencing NMDA-Receptor Activation by Spontaneous Neurotransmission. eNeuro. vol 6. issue 3. 2020-03-30. PMID:31110134. |
to examine potential regulators of nmdar activation because of spontaneous glutamate release in cultured hippocampal neurons, we used gcamp6f imaging at single synapses in concert with confocal and super-resolution imaging. |
2020-03-30 |
2023-08-13 |
Not clear |
| Daniel M Kircher, Heather C Aziz, Regina A Mangieri, Richard A Morriset. Ethanol Experience Enhances Glutamatergic Ventral Hippocampal Inputs to D1 Receptor-Expressing Medium Spiny Neurons in the Nucleus Accumbens Shell. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 39. issue 13. 2020-03-18. PMID:30692226. |
virally mediated expression of channelrhodopsin in ventral hippocampal (vhipp) glutamate neurons of male mice allowed for selective activation of vhipp to d1-msn synapses. |
2020-03-18 |
2023-08-13 |
mouse |
| Ester Orav, Ilona Dowavic, Johanna Huupponen, Tomi Taira, Sari E Laur. NETO1 Regulates Postsynaptic Kainate Receptors in CA3 Interneurons During Circuit Maturation. Molecular neurobiology. vol 56. issue 11. 2020-03-13. PMID:31044365. |
kainate type ionotropic glutamate receptors (kars) are expressed in hippocampal interneurons and regulate interneuron excitability and gabaergic transmission. |
2020-03-13 |
2023-08-13 |
Not clear |
| Miguel Ángel López-Vázquez, Carla Estefanía Gama-García, Yoana Estrada-Reyes, Lorena Gaytán-Tocavén, José Miguel Cervantes Alfaro, María Esther Olvera-Corté. Neonatal Monosodium Glutamate Administration Disrupts Place Learning and Alters Hippocampal-Prefrontal Learning-Related Theta Activity in the Adult Rat. Neuroscience. vol 414. 2020-03-13. PMID:31299349. |
we wondered whether the place learning deficits observed in adult rats that had been neonatally treated with monosodium glutamate (msg), were related to altered theta patterns in the hippocampus and prelimbic cortex, which were recorded during place learning training in the morris maze. |
2020-03-13 |
2023-08-13 |
rat |
| Mitsuhiro Makino, Kaori Takahashi-Ito, Hiroyasu Murasawa, Akiko Pawlak, Yoshinori Kashimoto, Yutaka Kitan. Memantine ameliorates learning and memory disturbance and the behavioral and psychological symptoms of dementia in thiamine-deficient mice. Pharmacology, biochemistry, and behavior. vol 183. 2020-03-10. PMID:31175916. |
memantine did not have a significant effect on monoamine levels, but increased glutamate levels in the hippocampus in td mice. |
2020-03-10 |
2023-08-13 |
mouse |
| Dan-Dan Wang, Mei-Fang Jin, Dong-Jing Zhao, Hong N. Reduction of Mitophagy-Related Oxidative Stress and Preservation of Mitochondria Function Using Melatonin Therapy in an HT22 Hippocampal Neuronal Cell Model of Glutamate-Induced Excitotoxicity. Frontiers in endocrinology. vol 10. 2020-02-25. PMID:31440210. |
we investigated the impact and mechanism involved in mitochondrial function and the mitochondrial oxidative stress/autophagy regulator parameters of glutamate cytotoxicity in mouse ht22 hippocampal neurons. |
2020-02-25 |
2023-08-13 |
mouse |
| C Muñoz-Ballester, N Santana, E Perez-Jimenez, R Viana, F Artigas, P San. In vivo glutamate clearance defects in a mouse model of Lafora disease. Experimental neurology. vol 320. 2020-02-24. PMID:31108086. |
in this work, we present new in vivo evidence of a glt-1 dysfunction, contributing to increased levels of extracellular glutamate in the hippocampus of a mouse model of lafora disease (epm2b-/-, lacking the e3-ubiquitin ligase malin). |
2020-02-24 |
2023-08-13 |
mouse |
| C Muñoz-Ballester, N Santana, E Perez-Jimenez, R Viana, F Artigas, P San. In vivo glutamate clearance defects in a mouse model of Lafora disease. Experimental neurology. vol 320. 2020-02-24. PMID:31108086. |
in conclusion, the hippocampus of epm2b-/- mice presents an in vivo impairment in glutamate uptake which could contribute to epileptogenesis. |
2020-02-24 |
2023-08-13 |
mouse |
| Matthijs G Bossong, Mathilde Antoniades, Matilda Azis, Carly Samson, Beverley Quinn, Ilaria Bonoldi, Gemma Modinos, Jesus Perez, Oliver D Howes, James M Stone, Paul Allen, Philip McGuir. Association of Hippocampal Glutamate Levels With Adverse Outcomes in Individuals at Clinical High Risk for Psychosis. JAMA psychiatry. vol 76. issue 2. 2020-02-17. PMID:30427993. |
association of hippocampal glutamate levels with adverse outcomes in individuals at clinical high risk for psychosis. |
2020-02-17 |
2023-08-13 |
human |
| N A Rivero-Segura, Ma I Coronado-Mares, R Rincón-Heredia, I Pérez-Torres, T Montiel, N Pavón, E A Cabrera-Reyes, L Massieu, M Cerbó. Prolactin prevents mitochondrial dysfunction induced by glutamate excitotoxicity in hippocampal neurons. Neuroscience letters. vol 701. 2020-02-13. PMID:30790645. |
prolactin prevents mitochondrial dysfunction induced by glutamate excitotoxicity in hippocampal neurons. |
2020-02-13 |
2023-08-13 |
Not clear |
| Huynh Quoc Nguyen, Sahib Zada, Trang Huyen Lai, Trang Minh Pham, Jin Seok Hwang, Mahmoud Ahmed, Deok Ryong Ki. Calpain-dependent Beclin1 cleavage stimulates senescence-associated cell death in HT22 hippocampal cells under the oxidative stress conditions. Neuroscience letters. vol 701. 2020-02-13. PMID:30807795. |
in this study, we found that the 60-kda becn1 was specifically degraded to a 40-kda fragment in hippocampal ht22 cells treated with 5 mm glutamate. |
2020-02-13 |
2023-08-13 |
Not clear |
| Xue-Mei Han, Yan-Jie Qin, Ying Zhu, Xin-Lin Zhang, Nan-Xi Wang, Ying Rang, Xue-Jia Zhai, Yong-Ning L. Development of an underivatized LC-MS/MS method for quantitation of 14 neurotransmitters in rat hippocampus, plasma and urine: Application to CUMS induced depression rats. Journal of pharmaceutical and biomedical analysis. vol 174. 2020-02-06. PMID:31288191. |
therefore, this study developed an underivatized liquid chromatography tandem mass spectrometry (lc-ms/ms) method for simultaneous monitoring the 3 components of glutamate metabolism in rat hippocampus and 11 components of tryptophan and phenylalanine metabolism in rat hippocampus, plasma and urine, and applied it to investigate their changes in rats induced by chronic unpredictable mild stress (cums). |
2020-02-06 |
2023-08-13 |
rat |
| H Trantham-Davidson, A Lavi. Loss of dysbindin-1 affects GABAergic transmission in the PFC. Psychopharmacology. vol 236. issue 11. 2020-01-28. PMID:31201475. |
it has been shown that dystrobrevin-binding protein 1 gene that encodes the protein dysbindin-1 is associated with risk for cognitive deficits, and studies have shown decreases in glutamate and correlated decreases in dysbindin-1 protein in the prefrontal cortex (pfc) and hippocampus of post-mortem tissue from schizophrenia patients. |
2020-01-28 |
2023-08-13 |
mouse |
| Fengxia Li, Karen Liu, Ao Wang, Paul W R Harris, Mark H Vickers, Jian Gua. Cyclic glycine-proline administration normalizes high-fat diet-induced synaptophysin expression in obese rats. Neuropeptides. vol 76. 2020-01-23. PMID:31146894. |
the expression of hippocampal synaptophysin, glutamate receptor-1, gfap and striatal tyrosine-hydroxylase were also reduced in the hfd groups. |
2020-01-23 |
2023-08-13 |
rat |
| Roberto Laureano-Melo, Janaina Sena de Souza, Rodrigo Rodrigues da Conceição, Josie Marcelle Lira Albuquerque, Nayana Coutinho Rodrigues, Bruno Guimarães Marinho, Emerson Lopes Olivares, Gisele Giannocco, Wellington da Silva Côrte. Prenatal thyroxine treatment promotes anxiolysis in male Swiss mice offspring. Hormones and behavior. vol 108. 2020-01-22. PMID:30576638. |
in the hippocampus, t4 offspring had a higher expression of tryptophan hydroxylase 2 (tph2), serotonin transporter (sert) and glutamate decarboxylase 67 (gad 67) in comparison to controls. |
2020-01-22 |
2023-08-13 |
mouse |