| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Y Itano, T Murayama, Y Kitamura, Y Nomur. Glutamate inhibits adenylate cyclase activity in dispersed rat hippocampal cells directly via an N-methyl-D-aspartate-like metabotropic receptor. Journal of neurochemistry. vol 59. issue 3. 1992-09-09. PMID:1353790. |
in hippocampal membranes, glutamate, similar to carbachol, inhibited adenylate cyclase activity in a gtp-dependent manner. |
1992-09-09 |
2023-08-11 |
rat |
| Y Itano, T Murayama, Y Kitamura, Y Nomur. Glutamate inhibits adenylate cyclase activity in dispersed rat hippocampal cells directly via an N-methyl-D-aspartate-like metabotropic receptor. Journal of neurochemistry. vol 59. issue 3. 1992-09-09. PMID:1353790. |
the effect of glutamate on camp accumulation was observed in an assay medium containing 0.7 mm mgcl2, which is known to inhibit both ionotropic nmda receptor/channels in the hippocampus and metabotropic nmda receptors in the cerebellum. |
1992-09-09 |
2023-08-11 |
rat |
| N G Weilan. Estradiol selectively regulates agonist binding sites on the N-methyl-D-aspartate receptor complex in the CA1 region of the hippocampus. Endocrinology. vol 131. issue 2. 1992-09-02. PMID:1353442. |
both of these activities are modulated by the excitatory neurotransmitter glutamate in the hippocampus. |
1992-09-02 |
2023-08-11 |
Not clear |
| N G Weilan. Estradiol selectively regulates agonist binding sites on the N-methyl-D-aspartate receptor complex in the CA1 region of the hippocampus. Endocrinology. vol 131. issue 2. 1992-09-02. PMID:1353442. |
to assess the hypothesis that estradiol increases the sensitivity of the hippocampus to glutamate activation by increasing glutamate binding sites, the densities of n-methyl-d-aspartate (nmda) agonist sites (determined by nmda displaced glutamate), competitive antagonist sites (cgp 39653), noncompetitive antagonist sites (mk801) as well as the non-nmda glutamate receptors for kainate and ampa (using kainate and cnqx, respectively) were measured using autoradiographic procedures. |
1992-09-02 |
2023-08-11 |
Not clear |
| N G Weilan. Estradiol selectively regulates agonist binding sites on the N-methyl-D-aspartate receptor complex in the CA1 region of the hippocampus. Endocrinology. vol 131. issue 2. 1992-09-02. PMID:1353442. |
the increase in nmda agonist sites with ovarian hormone treatment should result in an increase in the sensitivity of the hippocampus to glutamate activation which may mediate some of the effects of estradiol on learning and epileptic seizure activity. |
1992-09-02 |
2023-08-11 |
Not clear |
| A Baskys, R C Malenk. Agonists at metabotropic glutamate receptors presynaptically inhibit EPSCs in neonatal rat hippocampus. The Journal of physiology. vol 444. 1992-08-31. PMID:1668353. |
agonists at metabotropic glutamate receptors presynaptically inhibit epscs in neonatal rat hippocampus. |
1992-08-31 |
2023-08-11 |
rat |
| A Baskys, R C Malenk. Agonists at metabotropic glutamate receptors presynaptically inhibit EPSCs in neonatal rat hippocampus. The Journal of physiology. vol 444. 1992-08-31. PMID:1668353. |
the effects of metabotropic glutamate receptor agonists on excitatory synaptic transmission in the ca1 region of rat hippocampal slices (11-30 days) were studied using extracellular and whole-cell patch-clamp recording techniques. |
1992-08-31 |
2023-08-11 |
rat |
| G Y Hu, J F Stor. 2-Amino-3-phosphonopropionate fails to block postsynaptic effects of metabotropic glutamate receptors in rat hippocampal neurones. Acta physiologica Scandinavica. vol 145. issue 2. 1992-08-26. PMID:1322019. |
2-amino-3-phosphonopropionate fails to block postsynaptic effects of metabotropic glutamate receptors in rat hippocampal neurones. |
1992-08-26 |
2023-08-11 |
rat |
| R V Dorman, T F Hamm, D S Damron, E J Freema. Modulation of glutamate release from hippocampal mossy fiber nerve endings by arachidonic acid and eicosanoids. Advances in experimental medicine and biology. vol 318. 1992-08-26. PMID:1353285. |
modulation of glutamate release from hippocampal mossy fiber nerve endings by arachidonic acid and eicosanoids. |
1992-08-26 |
2023-08-11 |
Not clear |
| R V Dorman, T F Hamm, D S Damron, E J Freema. Modulation of glutamate release from hippocampal mossy fiber nerve endings by arachidonic acid and eicosanoids. Advances in experimental medicine and biology. vol 318. 1992-08-26. PMID:1353285. |
hippocampal mossy fiber (mf) synaptosomes were used to investigate the role of arachidonate in the evoked accumulation of presynaptic ca2+ and the release of endogenous glutamate, since these nerve terminals express long-term potentiation and selectively release glutamate as the excitatory transmitter. |
1992-08-26 |
2023-08-11 |
Not clear |
| R K Kamboj, D D Schoepp, S Nutt, L Shekter, B Korczak, R A True, D M Zimmerman, M A Wosnic. Molecular structure and pharmacological characterization of humEAA2, a novel human kainate receptor subunit. Molecular pharmacology. vol 42. issue 1. 1992-08-21. PMID:1321949. |
a cdna encoding a novel human glutamate receptor subunit protein was isolated from a human hippocampal library. |
1992-08-21 |
2023-08-11 |
human |
| N Lindefors, M Ballarin, P Ernfors, T Falkenberg, H Persso. Stimulation of glutamate receptors increases expression of brain-derived neurotrophic factor mRNA in rat hippocampus. Annals of the New York Academy of Sciences. vol 648. 1992-08-21. PMID:1322082. |
stimulation of glutamate receptors increases expression of brain-derived neurotrophic factor mrna in rat hippocampus. |
1992-08-21 |
2023-08-11 |
rat |
| G Lonart, S Alagarsamy, R Ravula, J Wang, K M Johnso. Inhibition of the phospholipase C-linked metabotropic glutamate receptor by 2-amino-3-phosphonopropionate is dependent on extracellular calcium. Journal of neurochemistry. vol 59. issue 2. 1992-08-20. PMID:1321236. |
l-ap-3 (1 mm) also produced a stereoselective 2.3-fold increase in the efflux of glutamate from the hippocampal slices. |
1992-08-20 |
2023-08-11 |
rat |
| D Lekieffre, J Callebert, M Plotkine, R G Boul. Concomitant increases in the extracellular concentrations of excitatory and inhibitory amino acids in the rat hippocampus during forebrain ischemia. Neuroscience letters. vol 137. issue 1. 1992-08-07. PMID:1352633. |
the extracellular concentrations of aspartate, glutamate, glutamine, taurine and gamma-aminobutyric acid in the hippocampus were determined during and after forebrain ischemia (4-vessel model) in the unanaesthetized rat. |
1992-08-07 |
2023-08-11 |
rat |
| M Villalba, A Martínez-Serrano, C Börner, P Blanco, J Satrústegu. NMDA-induced increase in [Ca2+]i and 45Ca2+ uptake in acutely dissociated brain cells derived from adult rats. Brain research. vol 570. issue 1-2. 1992-07-31. PMID:1352174. |
the effects of glutamate and nmda on [ca2+]i measured with fluo3 and 45ca2+ uptake have been studied on preparations derived from hippocampus and cerebral cortex. |
1992-07-31 |
2023-08-11 |
rat |
| M Villalba, A Martínez-Serrano, C Börner, P Blanco, J Satrústegu. NMDA-induced increase in [Ca2+]i and 45Ca2+ uptake in acutely dissociated brain cells derived from adult rats. Brain research. vol 570. issue 1-2. 1992-07-31. PMID:1352174. |
glutamate (100 microm) and n-methyl-dl-aspartate (200 microm) increased [ca2+]i by 26-12 nm and 23-9 nm after 90 s in cerebral cortex and hippocampus, and stimulated 45ca2+ uptake about 16-10% in the same regions. |
1992-07-31 |
2023-08-11 |
rat |
| D G Winder, P J Con. Activation of metabotropic glutamate receptors in the hippocampus increases cyclic AMP accumulation. Journal of neurochemistry. vol 59. issue 1. 1992-07-24. PMID:1351930. |
activation of metabotropic glutamate receptors in the hippocampus increases cyclic amp accumulation. |
1992-07-24 |
2023-08-11 |
rat |
| D G Winder, P J Con. Activation of metabotropic glutamate receptors in the hippocampus increases cyclic AMP accumulation. Journal of neurochemistry. vol 59. issue 1. 1992-07-24. PMID:1351930. |
the selective metabotropic glutamate receptor agonist trans-1-aminocyclopentane-1,3-dicarboxylic acid (trans-acpd) stimulates phosphoinositide hydrolysis and elicits several physiological responses in rat hippocampal slices. |
1992-07-24 |
2023-08-11 |
rat |
| H Urushihara, M Tohda, Y Nomur. Selective potentiation of N-methyl-D-aspartate-induced current by protein kinase C in Xenopus oocytes injected with rat brain RNA. The Journal of biological chemistry. vol 267. issue 17. 1992-07-16. PMID:1318298. |
glutamate receptors and protein kinase c (pkc) may play significant roles in long-term potentiation in hippocampus. |
1992-07-16 |
2023-08-11 |
rat |
| A Mitani, Y Andou, K Kataok. Selective vulnerability of hippocampal CA1 neurons cannot be explained in terms of an increase in glutamate concentration during ischemia in the gerbil: brain microdialysis study. Neuroscience. vol 48. issue 2. 1992-07-16. PMID:1351267. |
excessive release of glutamate has been proposed to play a major role in ischemia-induced selective neuronal death in field ca1 of the hippocampus. |
1992-07-16 |
2023-08-11 |
Not clear |