| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| D H Penning, J Patrick, S Jimmo, J F Brie. Release of glutamate and gamma-aminobutyric acid in the ovine fetal hippocampus: ontogeny and effect of hypoxia. Journal of developmental physiology. vol 16. issue 5. 1992-10-06. PMID:1688088. |
the data indicate that both glutamate and gaba are present in the ovine fetal hippocampus, and can be released by depolarizing concentrations of potassium ion in the immature fetus. |
1992-10-06 |
2023-08-11 |
Not clear |
| D H Penning, J Patrick, S Jimmo, J F Brie. Release of glutamate and gamma-aminobutyric acid in the ovine fetal hippocampus: ontogeny and effect of hypoxia. Journal of developmental physiology. vol 16. issue 5. 1992-10-06. PMID:1688088. |
the lack of potassium ion-evoked efflux of glutamate and gaba in the mature fetal hippocampus may reflect a toxic response to this stimulus. |
1992-10-06 |
2023-08-11 |
Not clear |
| D H Penning, J Patrick, S Jimmo, J F Brie. Release of glutamate and gamma-aminobutyric acid in the ovine fetal hippocampus: ontogeny and effect of hypoxia. Journal of developmental physiology. vol 16. issue 5. 1992-10-06. PMID:1688088. |
prolonged, severe hypoxia (greater than 10 min) may be required to evoke efflux of glutamate in the developing fetal hippocampus. |
1992-10-06 |
2023-08-11 |
Not clear |
| A S Clark, C W Cotma. Adrenal hormone effects on hippocampal excitatory amino acid binding. Brain research. vol 585. issue 1-2. 1992-09-29. PMID:1355001. |
the influence of short-term adrenalectomy or corticosterone treatment on the binding of glutamate receptor subtypes in the rat hippocampus was explored using the technique of in vitro autoradiography. |
1992-09-29 |
2023-08-11 |
rat |
| A S Clark, C W Cotma. Adrenal hormone effects on hippocampal excitatory amino acid binding. Brain research. vol 585. issue 1-2. 1992-09-29. PMID:1355001. |
no striking effects of acute adrenalectomy on the distribution or density of any glutamate receptor subtype were observed in the hippocampus. |
1992-09-29 |
2023-08-11 |
rat |
| T Miyake, T Kitamur. Glutamine synthetase immunoreactivity in two types of mouse brain glial cells. Brain research. vol 586. issue 1. 1992-09-29. PMID:1380881. |
the gs-positive asteroid cells were present in the hippocampus, cerebral cortex, neostriatum, and cerebellar granular layer, where many synapse receptors for excitatory amino acids such as glutamate are densely distributed. |
1992-09-29 |
2023-08-11 |
mouse |
| J Gomeza, C Aragón, C Giméne. High-affinity transport of choline and amino acid neurotransmitters in synaptosomes from brain regions after lesioning the nucleus basalis magnocellularis of young and aged rats. Neurochemical research. vol 17. issue 4. 1992-09-28. PMID:1355270. |
uptake of choline, gaba, glutamate and glycine has also been studied in other areas of the brain, namely, hippocampus, olfactory bulb and cerebellum. |
1992-09-28 |
2023-08-11 |
rat |
| W Löscher, U Wahnschaffe, C Rundfeldt, D Hönack, H O Hoppe. Regional alterations in brain amino acids during the estrous cycle of the rat. Neurochemical research. vol 17. issue 10. 1992-09-24. PMID:1508307. |
a decreased glutamate level during proestrus was also found in thalamus, while both glutamate and gaba did not vary throughout estrous cycle in any of the other examined regions, including substantia nigra, amygdala, striatum, cortex and hippocampus. |
1992-09-24 |
2023-08-11 |
rat |
| S L Mironov, H D Lu. Glutamate selectively increases the high-threshold Ca2+ channel current in sensory and hippocampal neurons. Brain research. vol 580. issue 1-2. 1992-09-23. PMID:1354560. |
glutamate selectively increases the high-threshold ca2+ channel current in sensory and hippocampal neurons. |
1992-09-23 |
2023-08-11 |
rat |
| S L Mironov, H D Lu. Glutamate selectively increases the high-threshold Ca2+ channel current in sensory and hippocampal neurons. Brain research. vol 580. issue 1-2. 1992-09-23. PMID:1354560. |
previous studies resulted in conflicting conclusions that glutamate application either decreases or increases the activity of ca2+ channels in hippocampal neurons. |
1992-09-23 |
2023-08-11 |
rat |
| D K Ingram, P Garofalo, E L Spangler, C R Mantione, I Odano, E D Londo. Reduced density of NMDA receptors and increased sensitivity to dizocilpine-induced learning impairment in aged rats. Brain research. vol 580. issue 1-2. 1992-09-23. PMID:1387035. |
analysis of [3h]glutamate binding in these rats revealed a marked age-related decline in nmda receptor binding in hippocampus. |
1992-09-23 |
2023-08-11 |
rat |
| D K Ingram, P Garofalo, E L Spangler, C R Mantione, I Odano, E D Londo. Reduced density of NMDA receptors and increased sensitivity to dizocilpine-induced learning impairment in aged rats. Brain research. vol 580. issue 1-2. 1992-09-23. PMID:1387035. |
thus, compared to young rats, aged rats were more sensitive to the behavioral effects of nmda receptor antagonism and they showed a hippocampal loss of [3h]glutamate in binding, which may be related to the increased sensitivity to dizocilpine. |
1992-09-23 |
2023-08-11 |
rat |
| M Tamaru, Y Yoneda, K Ogita, J Shimizu, T Matsutani, Y Nagat. Excitatory amino acid receptors in brains of rats with methylazoxymethanol-induced microencephaly. Neuroscience research. vol 14. issue 1. 1992-09-21. PMID:1324453. |
in the cortex and hippocampus of mam-rats, total bindings of [3h]glutamate (glu) (which is sensitive to n-methyl-d-aspartate (nmda) receptor), and strychnine-insensitive [3h]glycine (gly) and (+)-5-[3h]methyl-10,11-dihydro-5h-dibenzo[a,d]cyclohepten-5,10-imi ne (mk-801; a noncompetitive antagonist of nmda receptor), were reduced to approximately 40% of those in controls. |
1992-09-21 |
2023-08-11 |
rat |
| Y Minamoto, T Itano, M Tokuda, H Matsui, N A Janjua, K Hosokawa, Y Okada, T H Murakami, T Negi, O Hatas. In vivo microdialysis of amino acid neurotransmitters in the hippocampus in amygdaloid kindled rat. Brain research. vol 573. issue 2. 1992-09-18. PMID:1354551. |
extracellular concentrations of gamma-aminobutyric acid (gaba), glutamate (glu) and aspartate (asp) were determined by microdialysis in rat hippocampus during various amygdaloid kindled stages. |
1992-09-18 |
2023-08-11 |
rat |
| M Segal, V Greenberge. Acidic amino acids evoke a smaller [Ca2+]i rise in GABAergic than non-GABAergic hippocampal neurons. Neuroscience letters. vol 140. issue 2. 1992-09-17. PMID:1380146. |
changes in intracellular calcium concentration ([ca2+]i) in response to topical application of the glutamate agonists n-methyl-d-aspartate (nmda), or amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (ampa) were measured in cultured rat hippocampal neurons loaded with fluo-3 and visualized in a confocal laser scanning microscope. |
1992-09-17 |
2023-08-11 |
rat |
| J C Chen, M Chesle. pH transients evoked by excitatory synaptic transmission are increased by inhibition of extracellular carbonic anhydrase. Proceedings of the National Academy of Sciences of the United States of America. vol 89. issue 16. 1992-09-15. PMID:1380165. |
extracellular alkaline transients, measured with ph-sensitive microelectrodes, were generated in the ca1 region of rat hippocampal slices by repetitive electrical stimulation of schaeffer collateral fibers or by local ejection of glutamate. |
1992-09-15 |
2023-08-11 |
rat |
| N Akaik. Metabotropic glutamate receptors in the rat hippocampus. Clinical neuropharmacology. vol 15 Suppl 1 Pt A. 1992-09-14. PMID:1323385. |
metabotropic glutamate receptors in the rat hippocampus. |
1992-09-14 |
2023-08-11 |
rat |
| C K Chen, F S Silverstein, M V Johnsto. N-methyl-D-aspartate-mediated injury enhances quisqualic acid-stimulated phosphoinositide turnover in perinatal rats. Journal of neurochemistry. vol 59. issue 3. 1992-09-09. PMID:1322976. |
previous work in our laboratory demonstrated that ischemic-hypoxic brain injury in postnatal day 7 rats causes a substantial increase in phosphoinositide (ppi) turnover stimulated by the glutamate analogue quisqualic acid (quis) in the hippocampus and striatum. |
1992-09-09 |
2023-08-11 |
rat |
| Y Itano, T Murayama, Y Kitamura, Y Nomur. Glutamate inhibits adenylate cyclase activity in dispersed rat hippocampal cells directly via an N-methyl-D-aspartate-like metabotropic receptor. Journal of neurochemistry. vol 59. issue 3. 1992-09-09. PMID:1353790. |
glutamate inhibits adenylate cyclase activity in dispersed rat hippocampal cells directly via an n-methyl-d-aspartate-like metabotropic receptor. |
1992-09-09 |
2023-08-11 |
rat |
| Y Itano, T Murayama, Y Kitamura, Y Nomur. Glutamate inhibits adenylate cyclase activity in dispersed rat hippocampal cells directly via an N-methyl-D-aspartate-like metabotropic receptor. Journal of neurochemistry. vol 59. issue 3. 1992-09-09. PMID:1353790. |
incubation of dispersed hippocampal cells from adult rats with glutamate or nmda decreased forskolin-stimulated cyclic amp (camp) accumulation; half-maximal effects were obtained with 5.6 +/- 2.2 and 6.4 +/- 2.3 microm, respectively. |
1992-09-09 |
2023-08-11 |
rat |