| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A Dahchour, P De Witt. Effect of repeated ethanol withdrawal on glutamate microdialysate in the hippocampus. Alcoholism, clinical and experimental research. vol 23. issue 10. 1999-11-30. PMID:10550004. |
effect of repeated ethanol withdrawal on glutamate microdialysate in the hippocampus. |
1999-11-30 |
2023-08-12 |
rat |
| A Dahchour, P De Witt. Effect of repeated ethanol withdrawal on glutamate microdialysate in the hippocampus. Alcoholism, clinical and experimental research. vol 23. issue 10. 1999-11-30. PMID:10550004. |
our previous studies, which identified that ethanol withdrawal is associated with increases in glutamate microdialysate in the nucleus accumbens and reaches a maximum at 12 hr, have now been extended in order to assess whether repeated cycles of chronic ethanol intoxication followed by 12 hr withdrawal periods on three occasions alters glutamate release in the hippocampus of male rats. |
1999-11-30 |
2023-08-12 |
rat |
| A Cardounel, W Regelson, M Kalim. Dehydroepiandrosterone protects hippocampal neurons against neurotoxin-induced cell death: mechanism of action. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.). vol 222. issue 2. 1999-11-30. PMID:10564538. |
dehydroepiandrosterone (dhea), an adrenal cortex hormone secreted in large quantities in humans, protects cells of the clonal mouse hippocampal cell line ht-22 against the excitatory amino acid glutamate (5 mm), and amyloid beta-protein (2 microm) toxicity in a dose-dependent manner with optimum protection obtained at 5 microm concentration of dhea. |
1999-11-30 |
2023-08-12 |
mouse |
| R P Sanzgiri, A Araque, P G Haydo. Prostaglandin E(2) stimulates glutamate receptor-dependent astrocyte neuromodulation in cultured hippocampal cells. Journal of neurobiology. vol 41. issue 2. 1999-11-26. PMID:10512979. |
prostaglandin e(2) stimulates glutamate receptor-dependent astrocyte neuromodulation in cultured hippocampal cells. |
1999-11-26 |
2023-08-12 |
rat |
| H Liu, Y Cao, A I Basbaum, A M Mazarati, R Sankar, C G Wasterlai. Resistance to excitotoxin-induced seizures and neuronal death in mice lacking the preprotachykinin A gene. Proceedings of the National Academy of Sciences of the United States of America. vol 96. issue 21. 1999-11-24. PMID:10518582. |
recent evidence suggests that substance p (sp), a peptide that has been implicated in cardiovascular function, inflammatory responses, and nociception, also contributes to hippocampal excitability and status epilepticus, in part by enhancing glutamate release. |
1999-11-24 |
2023-08-12 |
mouse |
| A L Sherwi. Neuroactive amino acids in focally epileptic human brain: a review. Neurochemical research. vol 24. issue 11. 1999-11-24. PMID:10555779. |
glutamate decarboxylase (gad), responsible for gaba synthesis, is diminished in interneurons in discrete regions of epileptogenic cortex and hippocampus. |
1999-11-24 |
2023-08-12 |
human |
| S M Fitzjohn, A E Kingston, D Lodge, G L Collingridg. DHPG-induced LTD in area CA1 of juvenile rat hippocampus; characterisation and sensitivity to novel mGlu receptor antagonists. Neuropharmacology. vol 38. issue 10. 1999-11-22. PMID:10530819. |
we have used extracellular microelectrode recording to characterise a form of long-term depression (ltd) of synaptic transmission that can be induced by metabotropic glutamate (mglu) receptor activation in the ca1 region of the young (12-18 day old) rat hippocampus. |
1999-11-22 |
2023-08-12 |
rat |
| D E Pellegrini-Giampietro, F Peruginelli, E Meli, A Cozzi, S Albani-Torregrossa, R Pellicciari, F Moron. Protection with metabotropic glutamate 1 receptor antagonists in models of ischemic neuronal death: time-course and mechanisms. Neuropharmacology. vol 38. issue 10. 1999-11-22. PMID:10530822. |
in order to study the role of metabotropic glutamate 1 (mglu1) receptors in ischemic neuronal death, we examined the effects of the recently characterized and relatively selective mglu1 receptor antagonists 1-aminoindan-1,5-dicarboxylic acid (aida) and (s)-(+)-2-(3'-carboxybicyclo[1.1.1]pentyl)-glycine (cbpg) in murine cortical cell cultures and rat organotypic hippocampal slices exposed to oxygen glucose deprivation (ogd) and in vivo, following transient global ischemia in gerbils. |
1999-11-22 |
2023-08-12 |
rat |
| G Riedel, J Micheau, A G Lam, E L Roloff, S J Martin, H Bridge, L de Hoz, B Poeschel, J McCulloch, R G Morri. Reversible neural inactivation reveals hippocampal participation in several memory processes. Nature neuroscience. vol 2. issue 10. 1999-11-19. PMID:10491611. |
to identify whether hippocampal activity contributes to these processes independently, we used a novel method of inactivating synaptic transmission using a water-soluble antagonist of ampa/kainate glutamate receptors. |
1999-11-19 |
2023-08-12 |
rat |
| S Smirnov, P Paalasmaa, M Uusisaari, J Voipio, K Kail. Pharmacological isolation of the synaptic and nonsynaptic components of the GABA-mediated biphasic response in rat CA1 hippocampal pyramidal cells. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 19. issue 21. 1999-11-19. PMID:10531429. |
high-frequency stimulation (hfs) applied to stratum radiatum of a rat hippocampal slice in the presence of ionotropic glutamate receptor antagonists evokes a biphasic gaba(a) receptor-dependent response in ca1 pyramidal neurons, with a brief hyperpolarizing ipsp (hipsp) followed by a long-lasting depolarization. |
1999-11-19 |
2023-08-12 |
rat |
| M Kneussel, J H Brandstätter, B Laube, S Stahl, U Müller, H Bet. Loss of postsynaptic GABA(A) receptor clustering in gephyrin-deficient mice. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 19. issue 21. 1999-11-19. PMID:10531433. |
both in brain sections and cultured hippocampal neurons derived from geph -/- mice, synaptic gaba(a) receptor clusters containing either the gamma2 or the alpha2 subunit were absent, whereas glutamate receptor subunits were normally localized at postsynaptic sites. |
1999-11-19 |
2023-08-12 |
mouse |
| M M Nicolle, P J Colombo, M Gallagher, M McKinne. Metabotropic glutamate receptor-mediated hippocampal phosphoinositide turnover is blunted in spatial learning-impaired aged rats. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 19. issue 21. 1999-11-19. PMID:10531462. |
metabotropic glutamate receptor-mediated hippocampal phosphoinositide turnover is blunted in spatial learning-impaired aged rats. |
1999-11-19 |
2023-08-12 |
rat |
| J A Alabadí, J L Thibault, E Pinard, J Seylaz, F Lasbenne. 7-Nitroindazole, a selective inhibitor of nNOS, increases hippocampal extracellular glutamate concentration in status epilepticus induced by kainic acid in rats. Brain research. vol 839. issue 2. 1999-11-17. PMID:10519054. |
7-nitroindazole, a selective inhibitor of nnos, increases hippocampal extracellular glutamate concentration in status epilepticus induced by kainic acid in rats. |
1999-11-17 |
2023-08-12 |
rat |
| J A Alabadí, J L Thibault, E Pinard, J Seylaz, F Lasbenne. 7-Nitroindazole, a selective inhibitor of nNOS, increases hippocampal extracellular glutamate concentration in status epilepticus induced by kainic acid in rats. Brain research. vol 839. issue 2. 1999-11-17. PMID:10519054. |
in this study, the influence of neuronally derived no on hippocampal glutamate extracellular concentration was investigated in conditions of intense metabolic activation, i.e., during status epilepticus induced by systemic kainic acid (ka). |
1999-11-17 |
2023-08-12 |
rat |
| J A Alabadí, J L Thibault, E Pinard, J Seylaz, F Lasbenne. 7-Nitroindazole, a selective inhibitor of nNOS, increases hippocampal extracellular glutamate concentration in status epilepticus induced by kainic acid in rats. Brain research. vol 839. issue 2. 1999-11-17. PMID:10519054. |
in group 2, the local application of 7-ni in the hippocampus during status epilepticus significantly increased extracellular glutamate and arginine concentrations, whereas citrulline concentration remained constant. |
1999-11-17 |
2023-08-12 |
rat |
| M L Rosa, J G Jefferys, M W Sanders, R C Pearso. Expression of mRNAs encoding flip isoforms of GluR1 and GluR2 glutamate receptors is increased in rat hippocampus in epilepsy induced by tetanus toxin. Epilepsy research. vol 36. issue 2-3. 1999-11-15. PMID:10515169. |
expression of mrnas encoding flip isoforms of glur1 and glur2 glutamate receptors is increased in rat hippocampus in epilepsy induced by tetanus toxin. |
1999-11-15 |
2023-08-12 |
rat |
| S Donnelly, C Loscher, K H Mills, M A Lync. Glycerol-induced seizure: involvement of IL-1beta and glutamate. Neuroreport. vol 10. issue 9. 1999-11-10. PMID:10501514. |
these results are consistent with previous data suggesting a modulatory effect of il-1beta on glutamate release in hippocampus. |
1999-11-10 |
2023-08-12 |
mouse |
| N W Daw, S N Reid, C J Beave. Development and function of metabotropic glutamate receptors in cat visual cortex. Journal of neurobiology. vol 41. issue 1. 1999-11-10. PMID:10504197. |
metabotropic glutamate receptors have been implicated in plasticity in the hippocampus and cerebellum. |
1999-11-10 |
2023-08-12 |
cat |
| G Grecksch, A Becker, H Schroeder, V Höll. Involvement of delta-opioid receptors in pentylenetetrazol kindling development and kindling-related processes in rats. Naunyn-Schmiedeberg's archives of pharmacology. vol 360. issue 2. 1999-11-08. PMID:10494884. |
the kindling-induced increase in hippocampal glutamate binding was completely prevented by naltrindole, whereas the kindling-induced learning deficit was not influenced. |
1999-11-08 |
2023-08-12 |
rat |
| C R Jarvis, L Lilge, G J Vipond, R D Andre. Interpretation of intrinsic optical signals and calcein fluorescence during acute excitotoxic insult in the hippocampal slice. NeuroImage. vol 10. issue 4. 1999-11-05. PMID:10493895. |
glutamate agonist application evokes dramatic intrinsic optical signals (ioss) in the rat hippocampal slice preparation, particularly in the ca1 region. |
1999-11-05 |
2023-08-12 |
rat |