| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| K L Thomas, S Davis, S P Hunt, S Laroch. Alterations in the expression of specific glutamate receptor subunits following hippocampal LTP in vivo. Learning & memory (Cold Spring Harbor, N.Y.). vol 3. issue 2-3. 1999-09-09. PMID:10456090. |
alterations in the expression of specific glutamate receptor subunits following hippocampal ltp in vivo. |
1999-09-09 |
2023-08-12 |
rat |
| K L Thomas, S Davis, S P Hunt, S Laroch. Alterations in the expression of specific glutamate receptor subunits following hippocampal LTP in vivo. Learning & memory (Cold Spring Harbor, N.Y.). vol 3. issue 2-3. 1999-09-09. PMID:10456090. |
quantitative in situ hybridization revealed that following the induction of hippocampal long-term potentiation (ltp) in the dentate gyrus of freely moving rats, specific increases in the expression of the nr2b subunit of the n-methyl-d-aspartate (nmda) receptor and mglur1c, a short splice variant of the metabotropic glutamate receptors that are linked intracellularly to phospholipase c (plc) and protein kinase c (pkc), were seen in the postsynaptic dentate granule cells. |
1999-09-09 |
2023-08-12 |
rat |
| B McGahon, C Holscher, L McGlinchey, M J Rowan, M A Lync. Training in the Morris water maze occludes the synergism between ACPD and arachidonic acid on glutamate release in synaptosomes prepared from rat hippocampus. Learning & memory (Cold Spring Harbor, N.Y.). vol 3. issue 4. 1999-09-09. PMID:10456099. |
training in the morris water maze occludes the synergism between acpd and arachidonic acid on glutamate release in synaptosomes prepared from rat hippocampus. |
1999-09-09 |
2023-08-12 |
rat |
| B McGahon, C Holscher, L McGlinchey, M J Rowan, M A Lync. Training in the Morris water maze occludes the synergism between ACPD and arachidonic acid on glutamate release in synaptosomes prepared from rat hippocampus. Learning & memory (Cold Spring Harbor, N.Y.). vol 3. issue 4. 1999-09-09. PMID:10456099. |
however, the synergistic effect of arachidonic acid and acpd on glutamate release was occluded in hippocampal synaptosomes prepared from trained rats. |
1999-09-09 |
2023-08-12 |
rat |
| M Komatsu, Y Ueda, M Hiramats. Different changes in concentrations of monoamines and their metabolites and amino acids in various brain regions by the herbal medicine/Toki-Shakuyaku-San between female and male senescence-accelerated mice (SAMP8). Neurochemical research. vol 24. issue 7. 1999-09-08. PMID:10403621. |
the concentration of glutamate was decreased in the cortex, hippocampus, and striatum of female and male samp8 and not in female and male ddy mice. |
1999-09-08 |
2023-08-12 |
mouse |
| S L Chan, W S Griffin, M P Mattso. Evidence for caspase-mediated cleavage of AMPA receptor subunits in neuronal apoptosis and Alzheimer's disease. Journal of neuroscience research. vol 57. issue 3. 1999-09-08. PMID:10412022. |
western blot analyses using antibodies against different subunits of 2-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (ampa) and n-methyl-d-aspartate (nmda) types of ionotropic glutamate receptors indicate that ampa receptor subunits (glur1, glur2/3, and glur4), but not nmda receptor subunits (nr1 and nr2a), are proteolytically cleaved after exposure of hippocampal neurons to apoptotic insults, including abeta, and that the caspase inhibitor zvad-fmk suppresses such cleavage. |
1999-09-08 |
2023-08-12 |
Not clear |
| K Jun, G Choi, S G Yang, K Y Choi, H Kim, G C Chan, D R Storm, C Albert, G W Mayr, C J Lee, H S Shi. Enhanced hippocampal CA1 LTP but normal spatial learning in inositol 1,4,5-trisphosphate 3-kinase(A)-deficient mice. Learning & memory (Cold Spring Harbor, N.Y.). vol 5. issue 4-5. 1999-09-08. PMID:10454357. |
nevertheless, no significant difference was detected in the hippocampal neuronal cells of the wild-type and the mutant mice in the kinetics of ca2+ regulation after glutamate stimulation. |
1999-09-08 |
2023-08-12 |
mouse |
| R Ventura, K M Harri. Three-dimensional relationships between hippocampal synapses and astrocytes. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 19. issue 16. 1999-09-01. PMID:10436047. |
recent studies show that glutamate transporter-mediated currents occur in astrocytes when glutamate is released from hippocampal synapses. |
1999-09-01 |
2023-08-12 |
rat |
| R Ventura, K M Harri. Three-dimensional relationships between hippocampal synapses and astrocytes. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 19. issue 16. 1999-09-01. PMID:10436047. |
other studies suggest that astrocytes extend processes toward higher concentrations of glutamate; thus the presence of astrocytic processes at particular hippocampal synapses might signal which ones are releasing glutamate. |
1999-09-01 |
2023-08-12 |
rat |
| R Ventura, K M Harri. Three-dimensional relationships between hippocampal synapses and astrocytes. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 19. issue 16. 1999-09-01. PMID:10436047. |
these morphological arrangements suggest that the glutamate released at approximately two-thirds of hippocampal synapses might diffuse to other synapses, unless neuronal glutamate transporters are more effective than previously reported. |
1999-09-01 |
2023-08-12 |
rat |
| R Ventura, K M Harri. Three-dimensional relationships between hippocampal synapses and astrocytes. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 19. issue 16. 1999-09-01. PMID:10436047. |
the findings also suggest that physiological recordings made from hippocampal astrocytes do not uniformly sample the glutamate released from all hippocampal synapses. |
1999-09-01 |
2023-08-12 |
rat |
| M Tolar, J N Keller, S Chan, M P Mattson, M A Marques, K A Crutche. Truncated apolipoprotein E (ApoE) causes increased intracellular calcium and may mediate ApoE neurotoxicity. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 19. issue 16. 1999-09-01. PMID:10436064. |
the rise in intracellular calcium and the hippocampal cell death caused by the apoe peptide were significantly reduced by receptor-associated protein, removal of extracellular calcium, or administration of the specific nmda glutamate receptor antagonist mk-801. |
1999-09-01 |
2023-08-12 |
rat |
| G M Khan, I Smolders, H Lindekens, J Manil, G Ebinger, Y Michott. Effects of diazepam on extracellular brain neurotransmitters in pilocarpine-induced seizures in rats. European journal of pharmacology. vol 373. issue 2-3. 1999-08-30. PMID:10414434. |
pilocarpine-induced increases in the extracellular levels of glutamate and dopamine in hippocampus were promptly reduced by diazepam. |
1999-08-30 |
2023-08-12 |
rat |
| G M Khan, I Smolders, H Lindekens, J Manil, G Ebinger, Y Michott. Effects of diazepam on extracellular brain neurotransmitters in pilocarpine-induced seizures in rats. European journal of pharmacology. vol 373. issue 2-3. 1999-08-30. PMID:10414434. |
our findings suggest that the anti-convulsant action of diazepam against pilocarpine-induced seizures is associated with a prompt attenuation of extracellular hippocampal glutamate overflow without concurrent alteration of pilocarpine-induced increases in endogenous gaba levels. |
1999-08-30 |
2023-08-12 |
rat |
| N A Lozovaya, M V Kopanitsa, Y A Boychuk, O A Krishta. Enhancement of glutamate release uncovers spillover-mediated transmission by N-methyl-D-aspartate receptors in the rat hippocampus. Neuroscience. vol 91. issue 4. 1999-08-24. PMID:10391439. |
enhancement of glutamate release uncovers spillover-mediated transmission by n-methyl-d-aspartate receptors in the rat hippocampus. |
1999-08-24 |
2023-08-12 |
rat |
| N A Lozovaya, M V Kopanitsa, Y A Boychuk, O A Krishta. Enhancement of glutamate release uncovers spillover-mediated transmission by N-methyl-D-aspartate receptors in the rat hippocampus. Neuroscience. vol 91. issue 4. 1999-08-24. PMID:10391439. |
properties of excitatory postsynaptic currents during increased glutamate release were investigated by means of a whole-cell voltage-clamp in ca1 pyramidal neurons of rat hippocampal slices. |
1999-08-24 |
2023-08-12 |
rat |
| H P Frizelle, D C Moriarty, J J O'Conno. The combined effects of halothane and lamotrigine on excitatory postsynaptic potentials and use-dependent block in the rat dentate gyrus in vitro. Anesthesia and analgesia. vol 89. issue 2. 1999-08-24. PMID:10439774. |
halothane dose-dependently suppresses glutamate receptor-mediated excitatory postsynaptic potentials (epsps) in the rat hippocampus. |
1999-08-24 |
2023-08-12 |
rat |
| D Jabaudon, K Shimamoto, Y Yasuda-Kamatani, M Scanziani, B H Gähwiler, U Gerbe. Inhibition of uptake unmasks rapid extracellular turnover of glutamate of nonvesicular origin. Proceedings of the National Academy of Sciences of the United States of America. vol 96. issue 15. 1999-08-23. PMID:10411944. |
by using the n-methyl-d-aspartate receptors of patched ca3 hippocampal neurons as "glutamate sensors," we observed that application of tboa onto organotypic hippocampal slices led to a rapid increase in extracellular glutamate concentration. |
1999-08-23 |
2023-08-12 |
Not clear |
| G Schmid, R Chittolini, L Raiteri, G Bonann. Differential effects of zinc on native GABA(A) receptor function in rat hippocampus and cerebellum. Neurochemistry international. vol 34. issue 5. 1999-08-19. PMID:10397368. |
hippocampal noradrenergic and cerebellar glutamatergic granule cell axon terminals possess gaba(a) receptors mediating enhancement of noradrenaline and glutamate release, respectively. |
1999-08-19 |
2023-08-12 |
rat |
| J W Geddes, N G Chang, D C Ackley, N S Soultanian, J P McGillis, R A Yoke. Postmortem elevation in extracellular glutamate in the rat hippocampus when brain temperature is maintained at physiological levels: implications for the use of human brain autopsy tissues. Brain research. vol 831. issue 1-2. 1999-08-18. PMID:10411988. |
postmortem elevation in extracellular glutamate in the rat hippocampus when brain temperature is maintained at physiological levels: implications for the use of human brain autopsy tissues. |
1999-08-18 |
2023-08-12 |
human |