| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| L P McCluskey, L A Lampso. Local immune regulation in the central nervous system by substance P vs. glutamate. Journal of neuroimmunology. vol 116. issue 2. 2001-08-16. PMID:11438168. |
in hippocampus, where the baseline response to ifn-gamma was lower, sp was ineffective, but blocking glutamate enhanced the response in a proportion of rats. |
2001-08-16 |
2023-08-12 |
rat |
| G Kortenbruck, E Berger, E J Speckmann, U Musshof. RNA editing at the Q/R site for the glutamate receptor subunits GLUR2, GLUR5, and GLUR6 in hippocampus and temporal cortex from epileptic patients. Neurobiology of disease. vol 8. issue 3. 2001-08-16. PMID:11442354. |
rna editing at the q/r site for the glutamate receptor subunits glur2, glur5, and glur6 in hippocampus and temporal cortex from epileptic patients. |
2001-08-16 |
2023-08-12 |
human |
| T Kimoto, T Tsurugizawa, Y Ohta, J Makino, Tamura Ho, Y Hojo, N Takata, S Kawat. Neurosteroid synthesis by cytochrome p450-containing systems localized in the rat brain hippocampal neurons: N-methyl-D-aspartate and calcium-dependent synthesis. Endocrinology. vol 142. issue 8. 2001-08-16. PMID:11459806. |
upon stimulation with n-methyl-d-aspartate, ca(2+) influx through the n-methyl-d-aspartate subtype of glutamate receptors occurred, and significant net production of pregnenolone and pregnenolone sulfate was observed in the hippocampus. |
2001-08-16 |
2023-08-12 |
rat |
| J L Perez, L Khatri, C Chang, S Srivastava, P Osten, E B Zif. PICK1 targets activated protein kinase Calpha to AMPA receptor clusters in spines of hippocampal neurons and reduces surface levels of the AMPA-type glutamate receptor subunit 2. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 21. issue 15. 2001-08-16. PMID:11466413. |
pick1 targets activated protein kinase calpha to ampa receptor clusters in spines of hippocampal neurons and reduces surface levels of the ampa-type glutamate receptor subunit 2. |
2001-08-16 |
2023-08-12 |
Not clear |
| M Runnerstam, F Bao, Y Huang, J Shi, E Gutierrez, A Hamberger, H A Hansson, D Viano, K Hagli. A new model for diffuse brain injury by rotational acceleration: II. Effects on extracellular glutamate, intracranial pressure, and neuronal apoptosis. Journal of neurotrauma. vol 18. issue 3. 2001-08-09. PMID:11284547. |
extracellular glutamate, glycine, and taurine increased significantly in the hippocampus within a few hours and remained high after 24 h. neuronal nuclei in the granule layers of the hippocampus and cerebellum were positive for c-jun after 24 h. little immunoreactivity was detected in the cerebral cortex. |
2001-08-09 |
2023-08-12 |
Not clear |
| H Koinig, Y Morimoto, M H Zorno. The combination of lamotrigine and mild hypothermia prevents ischemia-induced increase in hippocampal glutamate. Journal of neurosurgical anesthesiology. vol 13. issue 2. 2001-08-09. PMID:11294451. |
the combination of lamotrigine and mild hypothermia prevents ischemia-induced increase in hippocampal glutamate. |
2001-08-09 |
2023-08-12 |
Not clear |
| M Vigne. Regulation of spontaneous inhibitory synaptic transmission by endogenous glutamate via non-NMDA receptors in cultured rat hippocampal neurons. Neuropharmacology. vol 40. issue 6. 2001-08-09. PMID:11369028. |
regulation of spontaneous inhibitory synaptic transmission by endogenous glutamate via non-nmda receptors in cultured rat hippocampal neurons. |
2001-08-09 |
2023-08-12 |
rat |
| M Vigne. Regulation of spontaneous inhibitory synaptic transmission by endogenous glutamate via non-NMDA receptors in cultured rat hippocampal neurons. Neuropharmacology. vol 40. issue 6. 2001-08-09. PMID:11369028. |
the regulation of gamma-aminobutyric acid (gaba)-mediated spontaneous inhibitory synaptic transmission by endogenously released glutamate was studied in cultured rat hippocampal neurons. |
2001-08-09 |
2023-08-12 |
rat |
| M Vigne. Regulation of spontaneous inhibitory synaptic transmission by endogenous glutamate via non-NMDA receptors in cultured rat hippocampal neurons. Neuropharmacology. vol 40. issue 6. 2001-08-09. PMID:11369028. |
therefore, both ampa and kainate receptors can regulate inhibitory synaptic transmission in cultured hippocampal neurons, the former by tonic activation, the latter when the glutamate concentration is increased by impairing glutonate uptake. |
2001-08-09 |
2023-08-12 |
rat |
| V A Skeberdis, J Lan, T Opitz, X Zheng, M V Bennett, R S Zuki. mGluR1-mediated potentiation of NMDA receptors involves a rise in intracellular calcium and activation of protein kinase C. Neuropharmacology. vol 40. issue 7. 2001-08-09. PMID:11378156. |
mglur1-mediated potentiation of nmda receptors involves a rise in intracellular calcium and activation of protein kinase c. potentiation of ionotropic glutamate receptor activity by metabotropic glutamate receptors (mglurs) is thought to modulate activity at glutamatergic synapses in the hippocampus. |
2001-08-09 |
2023-08-12 |
xenopus_laevis |
| S V Vellucci, R F Parrott, M L Mimmac. Down-regulation of BDNF mRNA, with no effect on trkB or glucocorticoid receptor m RNAs, in the porcine hippocampus after acute dexamethasone treatment. Research in veterinary science. vol 70. issue 2. 2001-08-02. PMID:11356095. |
injection of the synthetic glucocorticoid, dexamethasone (dex, 5 mg kg(-1)) on gene expression for mr s, gr s, bdnf, trkb, and selected ionotropic glutamate receptor subunits (iglurs), in the porcine hippocampus. |
2001-08-02 |
2023-08-12 |
Not clear |
| Y Ben-Ar. Developing networks play a similar melody. Trends in neurosciences. vol 24. issue 6. 2001-08-02. PMID:11356508. |
relying on the giant depolarizing potentials that provide most of the synaptic activity in the developing hippocampus, this article reviews the common properties and generating mechanisms of these patterns, and particularly the role of the early depolarizing action of gaba(a) and glycine receptors and the sequential expression of gaba and glutamate synapses. |
2001-08-02 |
2023-08-12 |
Not clear |
| J E Lee, M A Yenari, G H Sun, L Xu, M R Emond, D Cheng, G K Steinberg, R G Giffar. Differential neuroprotection from human heat shock protein 70 overexpression in in vitro and in vivo models of ischemia and ischemia-like conditions. Experimental neurology. vol 170. issue 1. 2001-08-02. PMID:11421590. |
hippocampal, but not cortical neuron cultures from these same transgenic mice were also protected against oxygen-glucose deprivation and glutamate toxicity. |
2001-08-02 |
2023-08-12 |
mouse |
| C Lu, M P Mattso. Dimethyl sulfoxide suppresses NMDA- and AMPA-induced ion currents and calcium influx and protects against excitotoxic death in hippocampal neurons. Experimental neurology. vol 170. issue 1. 2001-08-02. PMID:11421595. |
we now report that concentrations of dmso to which neurons are typically exposed in experimental studies and in human patients (0.5-1.5%) inhibit glutamate responses in hippocampal neurons. |
2001-08-02 |
2023-08-12 |
human |
| H Koinig, V Vornik, C Rueda, M H Zorno. Lubeluzole inhibits accumulation of extracellular glutamate in the hippocampus during transient global cerebral ischemia. Brain research. vol 898. issue 2. 2001-07-26. PMID:11306016. |
lubeluzole inhibits accumulation of extracellular glutamate in the hippocampus during transient global cerebral ischemia. |
2001-07-26 |
2023-08-12 |
Not clear |
| I Harukuni, P D Hurn, B J Crai. Deleterious effect of beta-estradiol in a rat model of transient forebrain ischemia. Brain research. vol 900. issue 1. 2001-07-26. PMID:11325356. |
on the other hand, many other reported effects of estrogen in hippocampal area ca1 might confer increased sensitivity to ischemia, either by modulating the excitatory effects of glutamate or by modifying the inhibitory effects of gaba. |
2001-07-26 |
2023-08-12 |
rat |
| J Kilbride, A M Rush, M J Rowan, R Anwy. Presynaptic group II mGluR inhibition of short-term depression in the medial perforant path of the dentate gyrus in vitro. Journal of neurophysiology. vol 85. issue 6. 2001-07-26. PMID:11387397. |
inhibition of short-term plasticity by activation of presynaptic group ii metabotropic glutamate receptors (group ii mglur) was investigated in the medial perforant path of the dentate gyrus in the hippocampus in vitro. |
2001-07-26 |
2023-08-12 |
Not clear |
| T Kleppisch, V Voigt, R Allmann, S Offermann. G(alpha)q-deficient mice lack metabotropic glutamate receptor-dependent long-term depression but show normal long-term potentiation in the hippocampal CA1 region. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 21. issue 14. 2001-07-26. PMID:11438569. |
group i metabotropic glutamate receptors (mglur), which are linked to heterotrimeric g-proteins of the g(q) family (g(q) and g(11)), have been reported to facilitate both hippocampal ltp and ltd. to evaluate their functional role in synaptic plasticity, we studied ltd and ltp in the ca1 region of the hippocampus from wild-type, galpha(q)(-/-), and galpha(11)(-/-) mice. |
2001-07-26 |
2023-08-12 |
mouse |
| M Blaabjerg, B W Kristensen, C Bonde, J Zimme. The metabotropic glutamate receptor agonist 1S,3R-ACPD stimulates and modulates NMDA receptor mediated excitotoxicity in organotypic hippocampal slice cultures. Brain research. vol 898. issue 1. 2001-07-19. PMID:11292452. |
the metabotropic glutamate receptor agonist 1s,3r-acpd stimulates and modulates nmda receptor mediated excitotoxicity in organotypic hippocampal slice cultures. |
2001-07-19 |
2023-08-12 |
Not clear |
| M Blaabjerg, B W Kristensen, C Bonde, J Zimme. The metabotropic glutamate receptor agonist 1S,3R-ACPD stimulates and modulates NMDA receptor mediated excitotoxicity in organotypic hippocampal slice cultures. Brain research. vol 898. issue 1. 2001-07-19. PMID:11292452. |
the potential toxic effects of the metabotropic glutamate receptor agonist (1s,3r)-1-aminocyclopentane-1,3-dicarboxylic acid (acpd) and its interactions with the n-methyl-d-aspartate (nmda) receptor were studied in hippocampal brain slice cultures, using densitometric measurements of the cellular uptake of propidium iodide (pi) to quantify neuronal degeneration. |
2001-07-19 |
2023-08-12 |
Not clear |