| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Hajime Fujii, Masatoshi Inoue, Hiroyuki Okuno, Yoshikazu Sano, Sayaka Takemoto-Kimura, Kazuo Kitamura, Masanobu Kano, Haruhiko Bit. Nonlinear decoding and asymmetric representation of neuronal input information by CaMKIIα and calcineurin. Cell reports. vol 3. issue 4. 2013-11-06. PMID:23602566. |
to address this, we developed a dual fluorescence resonance energy transfer (fret) imaging platform and recorded camkiiα and calcineurin activities in hippocampal neurons while varying glutamate uncaging frequencies. |
2013-11-06 |
2023-08-12 |
Not clear |
| Silvia Lorrio, Vanessa Gómez-Rangel, Pilar Negredo, Javier Egea, Rafael Leon, Alejandro Romero, Tharine Dal-Cim, Mercedes Villarroya, Maria Isabel Rodriguez-Franco, Santiago Conde, Mariana P Arce, Jose María Roda, Antonio G García, Manuela G Lópe. Novel multitarget ligand ITH33/IQM9.21 provides neuroprotection in in vitro and in vivo models related to brain ischemia. Neuropharmacology. vol 67. 2013-11-04. PMID:23228428. |
in isolated hippocampal neurons, ith33/iqm9.21 reduced [ca(2+)](c) transients induced by a high k(+) depolarizing solution or glutamate. |
2013-11-04 |
2023-08-12 |
mouse |
| Shan-Xue Jin, Junko Arai, Xuejun Tian, Rajendra Kumar-Singh, Larry A Fei. Acquisition of contextual discrimination involves the appearance of a RAS-GRF1/p38 mitogen-activated protein (MAP) kinase-mediated signaling pathway that promotes long term potentiation (LTP). The Journal of biological chemistry. vol 288. issue 30. 2013-11-04. PMID:23766509. |
we previously showed that beginning at 1 month of age, ras-grf1 mediates nmda-type glutamate receptor (nmdar)-induction of long term depression in the ca1 region of the hippocampus of mice. |
2013-11-04 |
2023-08-12 |
mouse |
| Shan-Xue Jin, Junko Arai, Xuejun Tian, Rajendra Kumar-Singh, Larry A Fei. Acquisition of contextual discrimination involves the appearance of a RAS-GRF1/p38 mitogen-activated protein (MAP) kinase-mediated signaling pathway that promotes long term potentiation (LTP). The Journal of biological chemistry. vol 288. issue 30. 2013-11-04. PMID:23766509. |
here we show that beginning at 2 months of age, when mice first acquire the ability to discriminate between closely related contexts, ras-grf1 begins to contribute to the induction of long term potentiation (ltp) in the ca1 hippocampus by mediating the action of calcium-permeable, ampa-type glutamate receptors (cp-ampars). |
2013-11-04 |
2023-08-12 |
mouse |
| R Liljequis. Glycine modulates N-methyl-D-aspartic acid induced learning facilitation in rats. Amino acids. vol 10. issue 4. 2013-11-04. PMID:24178595. |
nmda at doses of 10 and 20mg/kg elevated the concentration of glycine but decreased the concentration of aspartate, glutamate and glutamine in the cortex and aspartate in the hippocampus. |
2013-11-04 |
2023-08-12 |
rat |
| R Liljequis. Glycine modulates N-methyl-D-aspartic acid induced learning facilitation in rats. Amino acids. vol 10. issue 4. 2013-11-04. PMID:24178595. |
the coadministration of 5 mg/kg nmda with 5mg/kg milacemide elevated the concentrations of glycine, glutamate and glutamine in the cortex and taurine in the hippocampus. |
2013-11-04 |
2023-08-12 |
rat |
| Marco Milanese, Daniela Tardito, Laura Musazzi, Giulia Treccani, Alessandra Mallei, Tiziana Bonifacino, Cecilia Gabriel, Elisabeth Mocaer, Giorgio Racagni, Maurizio Popoli, Giambattista Bonann. Chronic treatment with agomelatine or venlafaxine reduces depolarization-evoked glutamate release from hippocampal synaptosomes. BMC neuroscience. vol 14. 2013-11-01. PMID:23895555. |
chronic treatment with agomelatine or venlafaxine reduces depolarization-evoked glutamate release from hippocampal synaptosomes. |
2013-11-01 |
2023-08-12 |
rat |
| Marco Milanese, Daniela Tardito, Laura Musazzi, Giulia Treccani, Alessandra Mallei, Tiziana Bonifacino, Cecilia Gabriel, Elisabeth Mocaer, Giorgio Racagni, Maurizio Popoli, Giambattista Bonann. Chronic treatment with agomelatine or venlafaxine reduces depolarization-evoked glutamate release from hippocampal synaptosomes. BMC neuroscience. vol 14. 2013-11-01. PMID:23895555. |
chronic antidepressants have been shown to dampen endogenous glutamate release from rat hippocampal synaptic terminals and to prevent the marked increase of glutamate overflow induced by acute behavioral stress in frontal/prefrontal cortex. |
2013-11-01 |
2023-08-12 |
rat |
| Xiaohong Xu, Lingdan Xie, Xing Hong, Qin Ruan, Hongfei Lu, Qin Zhang, Guangxia Zhang, Xingyi Li. Perinatal exposure to bisphenol-A inhibits synaptogenesis and affects the synaptic morphological development in offspring male mice. Chemosphere. vol 91. issue 8. 2013-10-30. PMID:23490186. |
given that synaptic structure of the hippocampus is closely related to behaviors, in the present study, we examined the effects of perinatal exposure to bpa (0.04, 0.4, and 4.0 mg kg(-1) day(-1)) on the synaptic density and the synaptic structural modification of pyramidal cells in hippocampus region ca1 and the expressions of synaptic proteins such as synapsin i and psd-95 and glutamate nmda and ampa receptors in male offspring mice on postnatal day (pnd) 14, 21, and 56. |
2013-10-30 |
2023-08-12 |
mouse |
| Anneleen Schallier, Katia Vermoesen, Ellen Loyens, Joeri Van Liefferinge, Yvette Michotte, Ilse Smolders, Ann Massi. L-Theanine intake increases threshold for limbic seizures but decreases threshold for generalized seizures. Nutritional neuroscience. vol 16. issue 2. 2013-10-29. PMID:23324588. |
moreover, we studied the effect of l-theanine intake on extracellular hippocampal and cortical glutamate and gamma-aminobutyric acid (gaba) levels, using in vivo microdialysis. |
2013-10-29 |
2023-08-12 |
mouse |
| Caren Bernardi, Ana Carolina Tramontina, Patrícia Nardin, Regina Biasibetti, Ana Paula Costa, Adriana Fernanda Vizueti, Cristiane Batassini, Lucas Silva Tortorelli, Krista Minéia Wartchow, Márcio Ferreira Dutra, Larissa Bobermin, Patrícia Sesterheim, André Quincozes-Santos, Jaqueline de Souza, Carlos Alberto Gonçalve. Treadmill exercise induces hippocampal astroglial alterations in rats. Neural plasticity. vol 2013. 2013-10-29. PMID:23401802. |
we investigated the effect of moderate treadmill exercise (20 min/day) for 4 weeks on some parameters of astrocytic activity in rat hippocampal slices, namely, glial fibrillary acidic protein (gfap), glutamate uptake and glutamine synthetase (gs) activities, glutathione content, and s100b protein content and secretion, as well as brain-derived neurotrophic factor (bdnf) levels and glucose uptake activity in this tissue. |
2013-10-29 |
2023-08-12 |
rat |
| Thomas Koeglsperger, Shaomin Li, Christian Brenneis, Jessica L Saulnier, Lior Mayo, Yijun Carrier, Dennis J Selkoe, Howard L Weine. Impaired glutamate recycling and GluN2B-mediated neuronal calcium overload in mice lacking TGF-β1 in the CNS. Glia. vol 61. issue 6. 2013-10-29. PMID:23536313. |
we found that depletion of tgf-β1 in the cns resulted in a loss of the astrocyte glutamate transporter (glut) proteins glt-1 (eaat2) and glast (eaat1) and decreased glutamate uptake in the mouse hippocampus. |
2013-10-29 |
2023-08-12 |
mouse |
| Thomas Koeglsperger, Shaomin Li, Christian Brenneis, Jessica L Saulnier, Lior Mayo, Yijun Carrier, Dennis J Selkoe, Howard L Weine. Impaired glutamate recycling and GluN2B-mediated neuronal calcium overload in mice lacking TGF-β1 in the CNS. Glia. vol 61. issue 6. 2013-10-29. PMID:23536313. |
cns-tgf-β1-deficient mice showed glun2b-dependent aberrant synaptic plasticity in the ca1 area of the hippocampus similar to the glutamate transport inhibitor dl-tboa and these mice were highly sensitive to excitotoxic injury. |
2013-10-29 |
2023-08-12 |
mouse |
| Thomas Koeglsperger, Shaomin Li, Christian Brenneis, Jessica L Saulnier, Lior Mayo, Yijun Carrier, Dennis J Selkoe, Howard L Weine. Impaired glutamate recycling and GluN2B-mediated neuronal calcium overload in mice lacking TGF-β1 in the CNS. Glia. vol 61. issue 6. 2013-10-29. PMID:23536313. |
in addition, hippocampal neurons from tgf-β1-deficient mice had elevated glun2b-mediated calcium signals in response to extrasynaptic glutamate receptor stimulation, whereas cells treated with tgf-β1 exhibited reduced glun2b-mediated calcium signals. |
2013-10-29 |
2023-08-12 |
mouse |
| Thomas Koeglsperger, Shaomin Li, Christian Brenneis, Jessica L Saulnier, Lior Mayo, Yijun Carrier, Dennis J Selkoe, Howard L Weine. Impaired glutamate recycling and GluN2B-mediated neuronal calcium overload in mice lacking TGF-β1 in the CNS. Glia. vol 61. issue 6. 2013-10-29. PMID:23536313. |
in summary, our study demonstrates a previously unrecognized function of tgf-β1 in the cns to control extracellular glutamate homeostasis and glun2b-mediated calcium responses in the mouse hippocampus. |
2013-10-29 |
2023-08-12 |
mouse |
| Andrés A Trabanco, José María Ci. mGluR2 positive allosteric modulators: a patent review (2009 - present). Expert opinion on therapeutic patents. vol 23. issue 5. 2013-10-28. PMID:23452205. |
high levels of mglu2 receptors are seen in brain areas such as prefrontal cortex, hippocampus and amygdala where glutamate hyperfunction may be implicated in disorders and diseases such as anxiety and schizophrenia. |
2013-10-28 |
2023-08-12 |
Not clear |
| A A Grolla, J A Sim, D Lim, J J Rodriguez, A A Genazzani, A Verkhratsk. Amyloid-β and Alzheimer's disease type pathology differentially affects the calcium signalling toolkit in astrocytes from different brain regions. Cell death & disease. vol 4. 2013-10-23. PMID:23661001. |
exposure to 100 nm of aβ resulted in increased expression of the metabotropic glutamate receptor type 5 (mglur5) and its downstream insp3 receptor type 1 (insp3r1) in hippocampal but not in ec astrocytes. |
2013-10-23 |
2023-08-12 |
mouse |
| Tharine Dal-Cim, Fabiana K Ludka, Wagner C Martins, Charlise Reginato, Esther Parada, Javier Egea, Manuela G López, Carla I Tasc. Guanosine controls inflammatory pathways to afford neuroprotection of hippocampal slices under oxygen and glucose deprivation conditions. Journal of neurochemistry. vol 126. issue 4. 2013-10-23. PMID:23713463. |
in conclusion, guo, by modulating adenosine receptor function and activating mapk/erk, affords neuroprotection of hippocampal slices subjected to ogd by a mechanism that implicates the following: (i) prevention of mitochondrial membrane depolarization, (ii) reduction of oxidative stress, (iii) regulation of inflammation by inhibition of nuclear factor kappa b and inducible nitric oxide synthase, and (iv) promoting glutamate uptake. |
2013-10-23 |
2023-08-12 |
Not clear |
| Petra Bonova, Jozef Burda, Viera Danielisova, Miroslava Nemethova, Miroslav Gottlie. Delayed post-conditioning reduces post-ischemic glutamate level and improves protein synthesis in brain. Neurochemistry international. vol 62. issue 6. 2013-10-22. PMID:23454191. |
however, increased glutamate was registered only in the hippocampus. |
2013-10-22 |
2023-08-12 |
Not clear |
| Petra Bonova, Jozef Burda, Viera Danielisova, Miroslava Nemethova, Miroslav Gottlie. Delayed post-conditioning reduces post-ischemic glutamate level and improves protein synthesis in brain. Neurochemistry international. vol 62. issue 6. 2013-10-22. PMID:23454191. |
post-conditioning improves protein synthesis in ca1 and dentate gyrus and, surprisingly, leads to 50% reduction in glutamate in whole hippocampus and cortex. |
2013-10-22 |
2023-08-12 |
Not clear |