| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Inah Lee, Frances Soliva. The roles of the medial prefrontal cortex and hippocampus in a spatial paired-association task. Learning & memory (Cold Spring Harbor, N.Y.). vol 15. issue 5. 2008-07-21. PMID:18463175. |
when the mpfc was inactivated by muscimol (gaba(a) receptor agonist) in the normal animals with intact hippocampi, they showed the same severe impairment as seen in the hippocampal lesioned rats only in object-in-place arms. |
2008-07-21 |
2023-08-12 |
rat |
| José Antonio López-Moreno, Gustavo González-Cuevas, Guillermo Moreno, Miguel Navarr. The pharmacology of the endocannabinoid system: functional and structural interactions with other neurotransmitter systems and their repercussions in behavioral addiction. Addiction biology. vol 13. issue 2. 2008-07-08. PMID:18422831. |
moreover, the neurotransmitter with the fewest number of related studies is acetylcholine (excepting in the hippocampus), whereas there is a large number that evaluates gaba, glutamate and dopamine. |
2008-07-08 |
2023-08-12 |
Not clear |
| T V Gerdjikov, U Rudolph, R Keist, H Möhler, J Feldon, B K Ye. Hippocampal alpha 5 subunit-containing GABA A receptors are involved in the development of the latent inhibition effect. Neurobiology of learning and memory. vol 89. issue 2. 2008-07-03. PMID:17638582. |
hippocampal alpha 5 subunit-containing gaba a receptors are involved in the development of the latent inhibition effect. |
2008-07-03 |
2023-08-12 |
mouse |
| T V Gerdjikov, U Rudolph, R Keist, H Möhler, J Feldon, B K Ye. Hippocampal alpha 5 subunit-containing GABA A receptors are involved in the development of the latent inhibition effect. Neurobiology of learning and memory. vol 89. issue 2. 2008-07-03. PMID:17638582. |
hippocampal gaba(a) receptors containing the alpha 5 subunit have been implicated in the modulation of hippocampal-dependent learning, presumably via their tonic inhibitory influence on hippocampal glutamatergic activity. |
2008-07-03 |
2023-08-12 |
mouse |
| T V Gerdjikov, U Rudolph, R Keist, H Möhler, J Feldon, B K Ye. Hippocampal alpha 5 subunit-containing GABA A receptors are involved in the development of the latent inhibition effect. Neurobiology of learning and memory. vol 89. issue 2. 2008-07-03. PMID:17638582. |
here, we examined the expression of latent inhibition (li)--a form of selective learning that is sensitive to a number of manipulations targeted at the hippocampal formation, in alpha 5(h105r) mutant mice with reduced levels of hippocampal alpha 5-containing gaba(a) receptors. |
2008-07-03 |
2023-08-12 |
mouse |
| T V Gerdjikov, U Rudolph, R Keist, H Möhler, J Feldon, B K Ye. Hippocampal alpha 5 subunit-containing GABA A receptors are involved in the development of the latent inhibition effect. Neurobiology of learning and memory. vol 89. issue 2. 2008-07-03. PMID:17638582. |
hence, a partial loss of hippocampal alpha 5 gaba(a) receptors is sufficient to alter one major form of selective learning, albeit this was not seen in the female. |
2008-07-03 |
2023-08-12 |
mouse |
| Desiree L Krebs-Kraft, Marise B Paren. Hippocampal infusions of glucose reverse memory deficits produced by co-infusions of a GABA receptor agonist. Neurobiology of learning and memory. vol 89. issue 2. 2008-07-03. PMID:17728160. |
hippocampal infusions of glucose reverse memory deficits produced by co-infusions of a gaba receptor agonist. |
2008-07-03 |
2023-08-12 |
rat |
| Desiree L Krebs-Kraft, Marise B Paren. Hippocampal infusions of glucose reverse memory deficits produced by co-infusions of a GABA receptor agonist. Neurobiology of learning and memory. vol 89. issue 2. 2008-07-03. PMID:17728160. |
the present experiments tested whether this negative interaction between glucose and gaba in the medial septum would be observed in the hippocampus, a brain region where glucose typically has positive effects on memory. |
2008-07-03 |
2023-08-12 |
rat |
| Desiree L Krebs-Kraft, Marise B Paren. Hippocampal infusions of glucose reverse memory deficits produced by co-infusions of a GABA receptor agonist. Neurobiology of learning and memory. vol 89. issue 2. 2008-07-03. PMID:17728160. |
specifically, we determined whether hippocampal infusions of glucose would reverse or exacerbate memory deficits produced by hippocampal co-infusions of the gaba receptor agonist muscimol. |
2008-07-03 |
2023-08-12 |
rat |
| Jarod Swant, Michael Stramiello, John J Wagne. Postsynaptic dopamine D3 receptor modulation of evoked IPSCs via GABA(A) receptor endocytosis in rat hippocampus. Hippocampus. vol 18. issue 5. 2008-07-01. PMID:18240318. |
postsynaptic dopamine d3 receptor modulation of evoked ipscs via gaba(a) receptor endocytosis in rat hippocampus. |
2008-07-01 |
2023-08-12 |
rat |
| Jarod Swant, Michael Stramiello, John J Wagne. Postsynaptic dopamine D3 receptor modulation of evoked IPSCs via GABA(A) receptor endocytosis in rat hippocampus. Hippocampus. vol 18. issue 5. 2008-07-01. PMID:18240318. |
our results suggest that the activation of d3 receptors can modulate gaba(a) receptor endocytosis in the hippocampus in a lamina specific manner, and thereby alter the efficacy of gabaergic transmission in the stratum radiatum of the ca1 region through a postsynaptic mechanism of action. |
2008-07-01 |
2023-08-12 |
rat |
| Héctor Romo-Parra, Mario Treviño, Uwe Heinemann, Rafael Gutiérre. GABA actions in hippocampal area CA3 during postnatal development: differential shift from depolarizing to hyperpolarizing in somatic and dendritic compartments. Journal of neurophysiology. vol 99. issue 3. 2008-06-12. PMID:18216229. |
gaba actions in hippocampal area ca3 during postnatal development: differential shift from depolarizing to hyperpolarizing in somatic and dendritic compartments. |
2008-06-12 |
2023-08-12 |
Not clear |
| Kelly J Skilbeck, Jennifer N O'Reilly, Graham A R Johnston, Tina Hinto. Antipsychotic drug administration differentially affects [3H]muscimol and [3H]flunitrazepam GABA(A) receptor binding sites. Progress in neuro-psychopharmacology & biological psychiatry. vol 32. issue 2. 2008-05-30. PMID:17976880. |
to broaden our understanding of the effects of antipsychotic drugs on gaba(a) receptors, we examined the saturation binding maximum (b(max)) and binding affinity (k(d)) of [3h]muscimol and [3h]flunitrazepam in the prefrontal cortex (pfc), hippocampus and thalamus of male sd rats that received a sucrose solution containing either haloperidol (1.5 mg/kg), olanzapine (6.5 mg/kg) or no drug daily for up to 28 days using quantitative receptor autoradiography. |
2008-05-30 |
2023-08-12 |
human |
| C E Adams, J C Yonchek, L Zheng, A C Collins, K E Steven. Altered hippocampal circuit function in C3H alpha7 null mutant heterozygous mice. Brain research. vol 1194. 2008-05-30. PMID:18199426. |
the alpha7 subtype of nicotinic receptor is highly expressed in the hippocampus where it is purported to modulate release of the inhibitory neurotransmitter gamma-aminobutyric acid (gaba). |
2008-05-30 |
2023-08-12 |
mouse |
| C E Adams, J C Yonchek, L Zheng, A C Collins, K E Steven. Altered hippocampal circuit function in C3H alpha7 null mutant heterozygous mice. Brain research. vol 1194. 2008-05-30. PMID:18199426. |
the alpha7 receptor-mediated release of gaba is thought to contribute to hippocampal inhibition (gating) of response to repetitive auditory stimulation. |
2008-05-30 |
2023-08-12 |
mouse |
| Murray B Herd, Alison R Haythornthwaite, Thomas W Rosahl, Keith A Wafford, Gregg E Homanics, Jeremy J Lambert, Delia Belell. The expression of GABAA beta subunit isoforms in synaptic and extrasynaptic receptor populations of mouse dentate gyrus granule cells. The Journal of physiology. vol 586. issue 4. 2008-05-29. PMID:18079158. |
the unambiguous identification of these distinct pools of synaptic and extrasynaptic gaba(a) receptors should aid our understanding of how they act in harmony, to regulate hippocampal signalling in health and disease. |
2008-05-29 |
2023-08-12 |
mouse |
| Yoshiyuki Asai, Akihiro Takano, Hiroshi Ito, Yoshiro Okubo, Masato Matsuura, Akihiko Otsuka, Hidehiko Takahashi, Tomomichi Ando, Shigeo Ito, Ryosuke Arakawa, Kunihiko Asai, Tetsuya Suhar. GABAA/Benzodiazepine receptor binding in patients with schizophrenia using [11C]Ro15-4513, a radioligand with relatively high affinity for alpha5 subunit. Schizophrenia research. vol 99. issue 1-3. 2008-05-27. PMID:18042347. |
gaba(a)/bz receptor including alpha5 subunit in the prefrontal cortex and hippocampus might be involved in the pathophysiology of negative symptoms of schizophrenia. |
2008-05-27 |
2023-08-12 |
human |
| Moslem Mohammadi, Esmaeel Ghani, Asghar Ghasemi, Ali Khoshbaten, Alireza Asgar. Synaptosomal GABA uptake decreases in paraoxon-treated rat brain. Toxicology. vol 244. issue 1. 2008-05-15. PMID:18055092. |
a synaptosomal model was used to evaluate in vivo effects of paraoxon on the uptake of [(3)h]gaba in rat cerebral cortex and hippocampus. |
2008-05-15 |
2023-08-12 |
rat |
| Moslem Mohammadi, Esmaeel Ghani, Asghar Ghasemi, Ali Khoshbaten, Alireza Asgar. Synaptosomal GABA uptake decreases in paraoxon-treated rat brain. Toxicology. vol 244. issue 1. 2008-05-15. PMID:18055092. |
0.1 mg/kg paraoxon significantly inhibited ache activity but only in the plasma for 4h, the activity was completely recovered at 18 h. gaba uptake was significantly (p<0.001) reduced in both cerebral cortex (18-32%) and hippocampal (16-23%) synaptosomes at all three time points after administering 0.7 mg/kg of paraoxon, a dose that seems to be sufficient to induce seizure activity. |
2008-05-15 |
2023-08-12 |
rat |
| Diana Cunha-Reis, Joaquim A Ribeiro, Ana M Sebastiã. A1 and A2A receptor activation by endogenous adenosine is required for VIP enhancement of K+ -evoked [3H]-GABA release from rat hippocampal nerve terminals. Neuroscience letters. vol 430. issue 3. 2008-05-13. PMID:18054436. |
vasoactive intestinal peptide (vip) modulates gaba release from hippocampal nerve terminals and enhances hippocampal synaptic transmission through a pathway dependent on gabaergic transmission. |
2008-05-13 |
2023-08-12 |
rat |