| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yijun Cui, Rui M Costa, Geoffrey G Murphy, Ype Elgersma, Yuan Zhu, David H Gutmann, Luis F Parada, Istvan Mody, Alcino J Silv. Neurofibromin regulation of ERK signaling modulates GABA release and learning. Cell. vol 135. issue 3. 2008-11-24. PMID:18984165. |
our results demonstrate that neurofibromin modulates erk/synapsin i-dependent gaba release, which in turn modulates hippocampal ltp and learning. |
2008-11-24 |
2023-08-12 |
mouse |
| Yijun Cui, Rui M Costa, Geoffrey G Murphy, Ype Elgersma, Yuan Zhu, David H Gutmann, Luis F Parada, Istvan Mody, Alcino J Silv. Neurofibromin regulation of ERK signaling modulates GABA release and learning. Cell. vol 135. issue 3. 2008-11-24. PMID:18984165. |
an nf1 heterozygous null mutation, which results in enhanced erk and synapsin i phosphorylation, increased gaba release in the hippocampus, and this was reversed by pharmacological downregulation of erk signaling. |
2008-11-24 |
2023-08-12 |
mouse |
| Yu Ren, Fu-Jun Zhang, Qing-Sheng Xue, Xin Zhao, Bu-Wei Y. Bilateral inhibition of gamma-aminobutyric acid type A receptor function within the basolateral amygdala blocked propofol-induced amnesia and activity-regulated cytoskeletal protein expression inhibition in the hippocampus. Anesthesiology. vol 109. issue 5. 2008-11-18. PMID:18946287. |
bilateral inhibition of gamma-aminobutyric acid type a receptor function within the basolateral amygdala blocked propofol-induced amnesia and activity-regulated cytoskeletal protein expression inhibition in the hippocampus. |
2008-11-18 |
2023-08-12 |
Not clear |
| Yu Ren, Fu-Jun Zhang, Qing-Sheng Xue, Xin Zhao, Bu-Wei Y. Bilateral inhibition of gamma-aminobutyric acid type A receptor function within the basolateral amygdala blocked propofol-induced amnesia and activity-regulated cytoskeletal protein expression inhibition in the hippocampus. Anesthesiology. vol 109. issue 5. 2008-11-18. PMID:18946287. |
based on these results, the authors hypothesized that the amnesia effect of propofol was partly due to its impairment of memory formation in the hippocampus through activating the bla gamma-aminobutyric acid type a receptor function. |
2008-11-18 |
2023-08-12 |
Not clear |
| Carlos A Lafourcade, Bradley E Alge. Distinctions among GABAA and GABAB responses revealed by calcium channel antagonists, cannabinoids, opioids, and synaptic plasticity in rat hippocampus. Psychopharmacology. vol 198. issue 4. 2008-11-17. PMID:18097653. |
hippocampal interneurons release gamma-aminobutyric acid (gaba) and produce fast gaba(a)- and slow gaba(b)-inhibitory postsynaptic potentials (ipsps). |
2008-11-17 |
2023-08-12 |
rat |
| Shaoyu Ge, Kurt A Sailor, Guo-li Ming, Hongjun Son. Synaptic integration and plasticity of new neurons in the adult hippocampus. The Journal of physiology. vol 586. issue 16. 2008-11-17. PMID:18499723. |
here we review recent findings on the synaptic integration and plasticity of newborn neurons in the adult hippocampus, including the basic biological process, unique characteristics, critical periods, and activity-dependent regulation by the neurotransmitters gaba and glutamate. |
2008-11-17 |
2023-08-12 |
Not clear |
| Silke D Meier, Karl W Kafitz, Christine R Ros. Developmental profile and mechanisms of GABA-induced calcium signaling in hippocampal astrocytes. Glia. vol 56. issue 10. 2008-11-10. PMID:18442094. |
using whole-cell patch-clamp and ratiometric calcium imaging in hippocampal slices from rats at postnatal days 3-34, we have analyzed the developmental profile as well as the cellular mechanisms of calcium signals induced by gaba(a) and gaba(b) receptor activation in astrocytes. |
2008-11-10 |
2023-08-12 |
rat |
| Silke D Meier, Karl W Kafitz, Christine R Ros. Developmental profile and mechanisms of GABA-induced calcium signaling in hippocampal astrocytes. Glia. vol 56. issue 10. 2008-11-10. PMID:18442094. |
moreover, gaba(b) receptor-mediated calcium signaling in astrocytes preferentially occurs at a period during postnatal development when hippocampal networks are established. |
2008-11-10 |
2023-08-12 |
rat |
| Anton Sheinin, Giuseppe Talani, Margaret I Davis, David M Lovinge. Endocannabinoid- and mGluR5-dependent short-term synaptic depression in an isolated neuron/bouton preparation from the hippocampal CA1 region. Journal of neurophysiology. vol 100. issue 2. 2008-11-05. PMID:18497350. |
in hippocampal slices, depolarization of the ca1 pyramidal neurons elicits an endocannabinoid-mediated inhibition of gamma-aminobutyric acid release known as depolarization-induced suppression of inhibition (dsi). |
2008-11-05 |
2023-08-12 |
Not clear |
| Alejandro Salah, Katherine L Perkin. Effects of subtype-selective group I mGluR antagonists on synchronous activity induced by 4-aminopyridine/CGP 55845 in adult guinea pig hippocampal slices. Neuropharmacology. vol 55. issue 1. 2008-11-05. PMID:18538357. |
co-application of the convulsant 4-aminopyridine (4-ap) and the gaba(b) receptor antagonist cgp 55845 to adult guinea pig hippocampal slices elicits giant gaba-mediated postsynaptic potentials (gpsps) and epileptiform discharges. |
2008-11-05 |
2023-08-12 |
Not clear |
| F Saraga, T Balena, T Wolansky, C T Dickson, M A Woodi. Inhibitory synaptic plasticity regulates pyramidal neuron spiking in the rodent hippocampus. Neuroscience. vol 155. issue 1. 2008-11-05. PMID:18562122. |
we demonstrate electrophysiologically that depolarizing e(gaba) by 24.7 mv increased the spontaneous action potential firing frequency of cultured hippocampal neurons 254% from 0.12+/-0.07 hz to 0.44+/-0.13 hz (n=11; p<0.05). |
2008-11-05 |
2023-08-12 |
rat |
| F Saraga, T Balena, T Wolansky, C T Dickson, M A Woodi. Inhibitory synaptic plasticity regulates pyramidal neuron spiking in the rodent hippocampus. Neuroscience. vol 155. issue 1. 2008-11-05. PMID:18562122. |
this study provides the first explanation of how depolarizing e(gaba) affects pyramidal cell output within the hippocampus. |
2008-11-05 |
2023-08-12 |
rat |
| E B Shubenina, V S Kudrin, P M Klodt, A A Pokrovskiĭ, T A Gudasheva, T A Voronina, R U Ostrovskai. [Interstrain differences in the content of excitatory and inhibitory amino acids in the brain of DBA/2J, Balb/c and C57BL/6 mice: characteristics of the effect of a dipeptide antipsychotic drug dilept]. Eksperimental'naia i klinicheskaia farmakologiia. vol 71. issue 4. 2008-10-27. PMID:18819433. |
we have performed a comparative study of the content of glutamate (glu), aspartate (asp), taurine (tau), glycine (gly) and gamma-amino-butyric acid (gaba) in the cortex, hippocampus, and striatum of the dba/2j, balb/c and c57bl/6 mice brain. |
2008-10-27 |
2023-08-12 |
mouse |
| E B Shubenina, V S Kudrin, P M Klodt, A A Pokrovskiĭ, T A Gudasheva, T A Voronina, R U Ostrovskai. [Interstrain differences in the content of excitatory and inhibitory amino acids in the brain of DBA/2J, Balb/c and C57BL/6 mice: characteristics of the effect of a dipeptide antipsychotic drug dilept]. Eksperimental'naia i klinicheskaia farmakologiia. vol 71. issue 4. 2008-10-27. PMID:18819433. |
the levels of glu, tau and gaba in dba/2j hippocampus was lower than those in other experimental strains. |
2008-10-27 |
2023-08-12 |
mouse |
| Karina J Vargas, Miho Terunuma, Judith A Tello, Menelas N Pangalos, Stephen J Moss, Andrés Couv. The availability of surface GABA B receptors is independent of gamma-aminobutyric acid but controlled by glutamate in central neurons. The Journal of biological chemistry. vol 283. issue 36. 2008-10-20. PMID:18579521. |
to understand the mechanisms that regulate the abundance of gaba(b) receptors, we have studied their turnover combining surface biotin labeling and a microscopic immunoendocytosis assay in hippocampal and cortical neurons. |
2008-10-20 |
2023-08-12 |
Not clear |
| Virág T Takács, Tamás F Freund, Attila I Gulyá. Types and synaptic connections of hippocampal inhibitory neurons reciprocally connected with the medial septum. The European journal of neuroscience. vol 28. issue 1. 2008-10-20. PMID:18662340. |
the morphological properties and connectivity of gamma-aminobutyric acid (gaba)ergic hippocampal cells projecting to the medial septum (hs cells) were examined in the rat. |
2008-10-20 |
2023-08-12 |
rat |
| C J Peddie, H A Davies, F M Colyer, M G Stewart, J J Rodrígue. Dendritic colocalisation of serotonin1B receptors and the glutamate NMDA receptor subunit NR1 within the hippocampal dentate gyrus: an ultrastructural study. Journal of chemical neuroanatomy. vol 36. issue 1. 2008-10-14. PMID:18572381. |
here, we have conducted an electron microscopic examination of the subcellular distribution of the 5-ht1br, nmda receptor subunit nr1 and neurotransmitter gamma-aminobutyric acid (gaba), within the hippocampal dentate gyrus. |
2008-10-14 |
2023-08-12 |
Not clear |
| Zeng-You Ye, Ke-Qing Zhou, Tian-Le Xu, Jiang-Ning Zho. Fluoxetine potentiates GABAergic IPSCs in rat hippocampal neurons. Neuroscience letters. vol 442. issue 1. 2008-10-14. PMID:18606211. |
this potentiation by fluoxetine may normalize the hippocampal gaba deficit during depression and in part exert its antidepressant activity. |
2008-10-14 |
2023-08-12 |
rat |
| Nese Dericioglu, Cheryl L Garganta, Ognen A Petroff, Dara Mendelsohn, Anne Williamso. Blockade of GABA synthesis only affects neural excitability under activated conditions in rat hippocampal slices. Neurochemistry international. vol 53. issue 1-2. 2008-10-10. PMID:18534717. |
blockade of gaba synthesis only affects neural excitability under activated conditions in rat hippocampal slices. |
2008-10-10 |
2023-08-12 |
rat |
| Nese Dericioglu, Cheryl L Garganta, Ognen A Petroff, Dara Mendelsohn, Anne Williamso. Blockade of GABA synthesis only affects neural excitability under activated conditions in rat hippocampal slices. Neurochemistry international. vol 53. issue 1-2. 2008-10-10. PMID:18534717. |
the primary goal of this study was to establish whether inhibition of gaba synthesis was sufficient to induce network hyperexcitability in a rat hippocampal slice model comparable to that seen with gaba receptor blockade. |
2008-10-10 |
2023-08-12 |
rat |