| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Camille Allène, Adriano Cattani, James B Ackman, Paolo Bonifazi, Laurent Aniksztejn, Yehezkel Ben-Ari, Rosa Cossar. Sequential generation of two distinct synapse-driven network patterns in developing neocortex. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 28. issue 48. 2009-01-26. PMID:19036979. |
these large-scale calcium waves were shown to be largely driven by glutamatergic synapses albeit gaba is a major excitatory neurotransmitter in the cortex at such early stages, mediating synapse-driven giant depolarizing potentials (gdps) in the hippocampus. |
2009-01-26 |
2023-08-12 |
rat |
| Katherine R Gililland-Kaufman, Michelle A Tanchuck, Matthew M Ford, John C Crabbe, Amy S Beadles-Bohling, Christopher Snelling, Gregory P Mark, Deborah A Fin. The neurosteroid environment in the hippocampus exerts bi-directional effects on seizure susceptibility in mice. Brain research. vol 1243. 2009-01-21. PMID:18840414. |
importantly, etoh withdrawal rendered wsp mice less sensitive to allo's anticonvulsant effect and more sensitive to fin's proconvulsant effect, suggesting an alteration in the sensitivity of hippocampal gaba(a) receptors in response to fluctuations in gabaergic neurosteroids during ethanol withdrawal. |
2009-01-21 |
2023-08-12 |
mouse |
| E Martín-García, M Pallaré. A post-training intrahippocampal anxiogenic dose of the neurosteroid pregnenolone sulfate impairs passive avoidance retention. Experimental brain research. vol 191. issue 2. 2009-01-16. PMID:18665356. |
as a control, we have injected the neurosteroid allopregnanolone (allop) into the hippocampus, which produces opposite behavioural and neurochemical profiles to those of pregs, by acting as a positive gaba(a) modulator and showing anxiolytic and sedative behavioural effects. |
2009-01-16 |
2023-08-12 |
human |
| Aleksandra Bortel, Lucyna Słomian, Dariusz Nitka, Michał Swierszcz, Mirella Jaksz, Beata Adamus-Sitkiewicz, Przemysław Nowak, Jadwiga Jośko, Richard M Kostrzewa, Ryszard Bru. Neonatal N-(-2-chloroethyl)-N-ethyl-2-bromobenzylamine (DSP-4) treatment modifies the vulnerability to phenobarbital- and ethanol-evoked sedative-hypnotic effects in adult rats. Pharmacological reports : PR. vol 60. issue 3. 2009-01-15. PMID:18622057. |
additionally, gaba concentration in the medial prefrontal cortex (pfc), hippocampus, cerebellum and brainstem was estimated by an hplc/ed method. |
2009-01-15 |
2023-08-12 |
rat |
| Aleksandra Bortel, Lucyna Słomian, Dariusz Nitka, Michał Swierszcz, Mirella Jaksz, Beata Adamus-Sitkiewicz, Przemysław Nowak, Jadwiga Jośko, Richard M Kostrzewa, Ryszard Bru. Neonatal N-(-2-chloroethyl)-N-ethyl-2-bromobenzylamine (DSP-4) treatment modifies the vulnerability to phenobarbital- and ethanol-evoked sedative-hypnotic effects in adult rats. Pharmacological reports : PR. vol 60. issue 3. 2009-01-15. PMID:18622057. |
while the endogenous gaba content in the pfc, hippocampus, brainstem and cerebellum of dsp-4-treated rats was not altered, phenobarbital significantly decreased gaba content of both intact and dsp-4-lesioned rats by approximately 40% in the hippocampus and by approximately 20% in other brain regions at 1 h. ethanol reduced gaba content by approximately 15-30% but only in the hippocampus and brainstem of both intact and lesioned rats. |
2009-01-15 |
2023-08-12 |
rat |
| Aleksandra Wisłowska-Stanek, Adam Hamed, Małgorzata Lehner, Andrzej Bidziński, Danuta Turzyńska, Alicja Sobolewska, Jerzy Walkowiak, Adam Płaźni. Effects of midazolam and buspirone on in vivo concentration of amino acids and monoamine metabolites in the rat hippocampus. Pharmacological reports : PR. vol 60. issue 2. 2009-01-09. PMID:18443382. |
the effects of anxiolytic doses of buspirone and midazolam (established in the conditioned fear test) on extracellular concentrations of glutamate, gaba, serotonin and dopamine metabolites in the hippocampus were examined in vivo, in freely moving rats. |
2009-01-09 |
2023-08-12 |
rat |
| J W Pan, I Cavus, J Kim, H P Hetherington, D D Spence. Hippocampal extracellular GABA correlates with metabolism in human epilepsy. Metabolic brain disease. vol 23. issue 4. 2009-01-09. PMID:18807158. |
hippocampal extracellular gaba correlates with metabolism in human epilepsy. |
2009-01-09 |
2023-08-12 |
human |
| J W Pan, I Cavus, J Kim, H P Hetherington, D D Spence. Hippocampal extracellular GABA correlates with metabolism in human epilepsy. Metabolic brain disease. vol 23. issue 4. 2009-01-09. PMID:18807158. |
we studied human epilepsy patients undergoing intracranial eeg monitoring for seizure localization to examine microdialysis measures of extracellular gaba (ecgaba), pre-operative mr spectroscopic measures of neuronal mitochondrial function (naa/cr), and wherever possible, neuropathology and hippocampal volumetry. |
2009-01-09 |
2023-08-12 |
human |
| M-C Roberge, C Messier, W A Staines, H Plamondo. Food restriction induces long-lasting recovery of spatial memory deficits following global ischemia in delayed matching and non-matching-to-sample radial arm maze tasks. Neuroscience. vol 156. issue 1. 2009-01-05. PMID:18672030. |
in the current study, this phenomenon was not associated with diet- and or ischemia-related alterations of vesicular glutamate transporter 1 expression in various hippocampal regions although lower vesicular gaba transporter immunostaining was present in the ca1 stratum oriens and the ca3 stratum radiatum in fr sham and ischemic rats. |
2009-01-05 |
2023-08-12 |
rat |
| Jim Y Tiao, Amyaouch Bradaia, Barbara Biermann, Klemens Kaupmann, Michaela Metz, Corinne Haller, Antonius G Rolink, Elin Pless, Paul N Barlow, Martin Gassmann, Bernhard Bettle. The sushi domains of secreted GABA(B1) isoforms selectively impair GABA(B) heteroreceptor function. The Journal of biological chemistry. vol 283. issue 45. 2008-12-23. PMID:18765663. |
soluble sd protein, when added at nanomolar concentrations to dissociated hippocampal neurons or to acute hippocampal slices, impairs the inhibitory effect of gaba(b) heteroreceptors on evoked and spontaneous glutamate release. |
2008-12-23 |
2023-08-12 |
Not clear |
| Ann Massie, Lieselotte Cnops, Ilse Smolders, Robert McCullumsmith, Ron Kooijman, Shin Kwak, Lutgarde Arckens, Yvette Michott. High-affinity Na+/K+-dependent glutamate transporter EAAT4 is expressed throughout the rat fore- and midbrain. The Journal of comparative neurology. vol 511. issue 2. 2008-12-22. PMID:18770868. |
relatively high levels of eaat4 protein were also detected in the hippocampal principal cells, in the glutamatergic, gamma-aminobutyric acid (gaba)ergic, dopaminergic and most likely cholinergic cells of all nuclei of the basal ganglia, and in neurons of layers ii/iii and v of the cerebral cortex. |
2008-12-22 |
2023-08-12 |
mouse |
| Jong-Hyun Son, Ursula H Winzer-Serha. Expression of neuronal nicotinic acetylcholine receptor subunit mRNAs in rat hippocampal GABAergic interneurons. The Journal of comparative neurology. vol 511. issue 2. 2008-12-22. PMID:18792073. |
the hippocampus receives cholinergic projections from the basal forebrain, and functional studies have suggested the presence of different subtypes of nicotinic acetylcholine receptors (achrs) on gamma-aminobutyric acid (gaba)ergic interneurons. |
2008-12-22 |
2023-08-12 |
rat |
| Qiang M. Beneficial effects of moderate voluntary physical exercise and its biological mechanisms on brain health. Neuroscience bulletin. vol 24. issue 4. 2008-12-19. PMID:18668156. |
the up-active pathway is associated with enhancements of several neurotransmitters systems afferent to hippocampus, including norepinephrine (ne), serotonin (5-hydroxytryptamine, 5-ht), acetylcholine (ach) and gamma-aminobutyric acid (gaba). |
2008-12-19 |
2023-08-12 |
Not clear |
| Xiao-Bing Zhang, Peng Jiang, Neng Gong, Xiao-Ling Hu, Da Fei, Zhi-Qi Xiong, Lin Xu, Tian-Le X. A-type GABA receptor as a central target of TRPM8 agonist menthol. PloS one. vol 3. issue 10. 2008-12-18. PMID:18852885. |
we found menthol not only enhanced the currents induced by low concentrations of gaba but also directly activated gaba(a) receptor (gaba(a)r) in hippocampal neurons in culture. |
2008-12-18 |
2023-08-12 |
rat |
| M S Nin, F B Salles, L A Azeredo, A P G Frazon, R Gomez, H M T Barro. Antidepressant effect and changes of GABAA receptor gamma2 subunit mRNA after hippocampal administration of allopregnanolone in rats. Journal of psychopharmacology (Oxford, England). vol 22. issue 5. 2008-12-16. PMID:18308780. |
our findings suggest that the gamma2, but not the alpha4 gaba(a) subunit, needs further evaluation to be involved in the antidepressant effect of allopregnanolone in the hippocampus and that there is a hemispheric diversity in the biochemical effect of the drug. |
2008-12-16 |
2023-08-12 |
rat |
| Frederico C Pereira, Marta R Rolo, Elsa Marques, Vera M Mendes, Carlos F Ribeiro, Syed F Ali, Teresa Morgadinho, Tice R Maced. Acute increase of the glutamate-glutamine cycling in discrete brain areas after administration of a single dose of amphetamine. Annals of the New York Academy of Sciences. vol 1139. 2008-12-09. PMID:18991867. |
), and the caudate-putamen (cpu), frontal cortex (fc), and hippocampus (hp) were dissected for analysis of glutamate (glu), gamma-aminobutyric acid (gaba), and gln. |
2008-12-09 |
2023-08-12 |
rat |
| Frederico C Pereira, Marta R Rolo, Elsa Marques, Vera M Mendes, Carlos F Ribeiro, Syed F Ali, Teresa Morgadinho, Tice R Maced. Acute increase of the glutamate-glutamine cycling in discrete brain areas after administration of a single dose of amphetamine. Annals of the New York Academy of Sciences. vol 1139. 2008-12-09. PMID:18991867. |
striatal gaba levels and gaba/glu ratio were increased (46 and 100%, respectively) at 24 h. in hippocampus the gaba/glu increase (60%) occurred as early as 4 h after treatment. |
2008-12-09 |
2023-08-12 |
rat |
| Shlomit Jacobson-Pick, Alina Elkobi, Shelly Vander, Kobi Rosenblum, Gal Richter-Levi. Juvenile stress-induced alteration of maturation of the GABAA receptor alpha subunit in the rat. The international journal of neuropsychopharmacology. vol 11. issue 7. 2008-12-08. PMID:18364065. |
in the present study, we examined the long-term effects of juvenile stress on gaba alpha subunit expression in adulthood in the amygdala and hippocampus. |
2008-12-08 |
2023-08-12 |
rat |
| Joyce Besheer, Jason P Schroeder, Rebekah A Stevenson, Clyde W Hodg. Ethanol-induced alterations of c-Fos immunoreactivity in specific limbic brain regions following ethanol discrimination training. Brain research. vol 1232. 2008-12-08. PMID:18692030. |
the discriminative stimulus properties of ethanol are functionally regulated by ionotropic gaba(a) and nmda receptors in specific limbic brain regions including the nucleus accumbens, amygdala, and hippocampus, as determined by microinjection studies. |
2008-12-08 |
2023-08-12 |
rat |
| Peter C Waldmeier, Klemens Kaupmann, Stephan Urwyle. Roles of GABAB receptor subtypes in presynaptic auto- and heteroreceptor function regulating GABA and glutamate release. Journal of neural transmission (Vienna, Austria : 1996). vol 115. issue 10. 2008-12-02. PMID:18665320. |
in cortical, hippocampal and striatal slices from both gaba b(1a)-/- and gaba b(1b)-/- mice, the frequency dependence of [3h]gaba released per pulse was maintained, suggesting that both isoforms participate or can substitute for each other in gaba b autoreceptor function. |
2008-12-02 |
2023-08-12 |
mouse |