| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Michael P Sceniak, M Bruce Macive. Slow GABA(A) mediated synaptic transmission in rat visual cortex. BMC neuroscience. vol 9. 2008-04-03. PMID:18199338. |
within the hippocampus, it has been shown that gaba(a) responses can take the form of either fast or slow response kinetics. |
2008-04-03 |
2023-08-12 |
rat |
| Taejib Yoon, Jeffrey Okada, Min W Jung, Jeansok J Ki. Prefrontal cortex and hippocampus subserve different components of working memory in rats. Learning & memory (Cold Spring Harbor, N.Y.). vol 15. issue 3. 2008-04-03. PMID:18285468. |
to investigate this issue, the mpfc and dorsal hippocampus (dhpc) were temporarily inactivated via targeted infusions of the gaba(a) receptor agonist muscimol in rats prior to their performance on a delayed alternation task (dat), employing an automated figure-eight maze that required the animals to make alternating arm choice responses after 3-, 30-, and 60-sec delays for water reward. |
2008-04-03 |
2023-08-12 |
rat |
| Joseph L Nuñez, Margaret M McCarth. Evidence for an extended duration of GABA-mediated excitation in the developing male versus female hippocampus. Developmental neurobiology. vol 67. issue 14. 2008-03-27. PMID:17823921. |
activation of gaba(a) receptors in neonatal rat hippocampus results in chloride efflux and membrane depolarization sufficient to open voltage sensitive calcium channels. |
2008-03-27 |
2023-08-12 |
rat |
| Joseph L Nuñez, Margaret M McCarth. Evidence for an extended duration of GABA-mediated excitation in the developing male versus female hippocampus. Developmental neurobiology. vol 67. issue 14. 2008-03-27. PMID:17823921. |
by the second postnatal week in the rat, gaba action in the hippocampus is predominantly inhibitory. |
2008-03-27 |
2023-08-12 |
rat |
| Joseph L Nuñez, Margaret M McCarth. Evidence for an extended duration of GABA-mediated excitation in the developing male versus female hippocampus. Developmental neurobiology. vol 67. issue 14. 2008-03-27. PMID:17823921. |
hippocampal neurons in the newborn male and female rat respond to gaba(a) receptor activation with increased intracellular calcium and are susceptible to gaba-mediated damage -- both being indicative of the excitatory nature of gaba. |
2008-03-27 |
2023-08-12 |
rat |
| Joseph L Nuñez, Margaret M McCarth. Evidence for an extended duration of GABA-mediated excitation in the developing male versus female hippocampus. Developmental neurobiology. vol 67. issue 14. 2008-03-27. PMID:17823921. |
in the present study we observed that by postnatal day 7, only males are susceptible to gaba(a) agonist-induced damage and respond to gaba(a) agonist administration with elevated levels of intracellular calcium in cultured hippocampal neurons. |
2008-03-27 |
2023-08-12 |
rat |
| Joseph L Nuñez, Margaret M McCarth. Evidence for an extended duration of GABA-mediated excitation in the developing male versus female hippocampus. Developmental neurobiology. vol 67. issue 14. 2008-03-27. PMID:17823921. |
this converging evidence infers that sex affects the duration of gaba(a) receptor-mediated excitation during normal hippocampal development, and provides a mechanism by which the effect is mediated. |
2008-03-27 |
2023-08-12 |
rat |
| Dominique M Durand, Alicia Jensen, Marom Bikso. Suppression of neural activity with high frequency stimulation. Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference. vol 2006. 2008-03-17. PMID:17946913. |
sinusoidal stimulation at 50 hz applied to the ca1 region of the hippocampus was observed to block epileptiform activity in three separate models of epilepsy induced by low-calcium, high potassium and picrotoxin (gaba a blocker). |
2008-03-17 |
2023-08-12 |
Not clear |
| P Maciejak, M Lehner, D Turzyńska, J Szyndler, A Bidziński, E Taracha, A Sobolewska, J Walkowiak, A Skórzewska, A Wisłowska, A Hamed, A Płaźni. The opposite role of hippocampal mGluR1 in fear conditioning in kindled and non-kindled rats. Brain research. vol 1187. 2008-03-17. PMID:18022605. |
in the present paper, we analyzed the effects of hippocampal mglur1 on the consolidation of a fear-conditioned response and on hippocampal glutamate and gaba concentration in rats subjected to the chemically-induced kindling of seizures. |
2008-03-17 |
2023-08-12 |
rat |
| Douglas A Coulter, Gregory C Carlso. Functional regulation of the dentate gyrus by GABA-mediated inhibition. Progress in brain research. vol 163. 2008-03-14. PMID:17765722. |
both synaptic and extrasynaptic gaba(a) receptors exhibit profound dysregulation in animal models of temporal lobe epilepsy, which may contribute to the hippocampal hyperexcitability that defines this disorder. |
2008-03-14 |
2023-08-12 |
Not clear |
| Maria Luisa Barbaccia, Sergio Scaccianoce, Paola Del Bianco, Patrizia Campolongo, Viviana Trezza, Maria Tattoli, Vincenzo Cuomo, Luca Steard. Cognitive impairment and increased brain neurosteroids in adult rats perinatally exposed to low millimolar blood alcohol concentrations. Psychoneuroendocrinology. vol 32. issue 8-10. 2008-03-11. PMID:17689019. |
the latter may be consequent to altered expression/activity of brain steroidogenic enzymes, as reflected by the enduring increase of the gaba(a) receptor-active neurosteroid 3alpha,5alpha-thp in brain cortex and hippocampus, but not in plasma. |
2008-03-11 |
2023-08-12 |
rat |
| C R Marutha Ravindran, Ashok K Mehta, Maharaj K Tick. Effect of chronic administration of ethanol on the regulation of the delta-subunit of GABA(A) receptors in the rat brain. Brain research. vol 1174. 2008-03-10. PMID:17854781. |
ce administration resulted a down-regulation of polypeptide levels of the delta-subunit of gaba(a) receptors in the rat cerebellum and hippocampus, whereas there were no changes in the delta-subunit polypeptide levels in the rat cerebral cortex. |
2008-03-10 |
2023-08-12 |
rat |
| Klaus B Fink, Manfred Göther. 5-HT receptor regulation of neurotransmitter release. Pharmacological reviews. vol 59. issue 4. 2008-03-06. PMID:18160701. |
conversely, attenuated gaba release in response to activation of inhibitory 5-ht heteroreceptors, e.g., 5-ht(1a) or 5-ht(1b) receptors on gabaergic interneurons is involved in paradoxical facilitation of hippocampal acetylcholine and striatal dopamine release, respectively. |
2008-03-06 |
2023-08-12 |
Not clear |
| Muhammad Mubarak Hossain, Tadahiko Suzuki, Toshihiro Unno, Seiichi Komori, Haruo Kobayash. Differential presynaptic actions of pyrethroid insecticides on glutamatergic and GABAergic neurons in the hippocampus. Toxicology. vol 243. issue 1-2. 2008-02-29. PMID:18023957. |
this study was designed to investigate the effects of several pyrethroids on the extracellular level of glutamate and gamma-aminobutyric acid (gaba) in the hippocampus of rats measured using microdialysis following systemic (i.p.) |
2008-02-29 |
2023-08-12 |
rat |
| Jerzy W Mozrzymas, Tomasz Wójtowicz, Michal Piast, Katarzyna Lebida, Paulina Wyrembek, Katarzyna Merci. GABA transient sets the susceptibility of mIPSCs to modulation by benzodiazepine receptor agonists in rat hippocampal neurons. The Journal of physiology. vol 585. issue Pt 1. 2008-02-25. PMID:17855751. |
gaba transient sets the susceptibility of mipscs to modulation by benzodiazepine receptor agonists in rat hippocampal neurons. |
2008-02-25 |
2023-08-12 |
rat |
| Joseph Glykys, Edward O Mann, Istvan Mod. Which GABA(A) receptor subunits are necessary for tonic inhibition in the hippocampus? The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 28. issue 6. 2008-02-25. PMID:18256262. |
which gaba(a) receptor subunits are necessary for tonic inhibition in the hippocampus? |
2008-02-25 |
2023-08-12 |
mouse |
| Joseph Glykys, Edward O Mann, Istvan Mod. Which GABA(A) receptor subunits are necessary for tonic inhibition in the hippocampus? The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 28. issue 6. 2008-02-25. PMID:18256262. |
gaba(a) receptors (gaba(a)rs) assembled of different subunits mediate tonic and phasic inhibition in hippocampal neurons. |
2008-02-25 |
2023-08-12 |
mouse |
| Joseph Glykys, Edward O Mann, Istvan Mod. Which GABA(A) receptor subunits are necessary for tonic inhibition in the hippocampus? The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 28. issue 6. 2008-02-25. PMID:18256262. |
to better identify the gaba(a)rs mediating tonic inhibition in hippocampal neurons, we generated mice lacking both alpha5 and delta subunits (gabra5/gabrd-/-). |
2008-02-25 |
2023-08-12 |
mouse |
| Joseph Glykys, Edward O Mann, Istvan Mod. Which GABA(A) receptor subunits are necessary for tonic inhibition in the hippocampus? The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 28. issue 6. 2008-02-25. PMID:18256262. |
in conclusion, depending on the cell type, the alpha5 and delta subunits are the principal gaba(a)r subunits responsible for mediating the lion's share of tonic inhibition in hippocampal neurons. |
2008-02-25 |
2023-08-12 |
mouse |
| Aristea S Galanopoulo. Dissociated gender-specific effects of recurrent seizures on GABA signaling in CA1 pyramidal neurons: role of GABA(A) receptors. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 28. issue 7. 2008-02-25. PMID:18272677. |
these data suggest that the direction of gaba(a)-receptor signaling may be a determining factor for the age and sex-specific effects of prolonged seizures in the hippocampus, because they relate to normal brain development and possibly epileptogenesis. |
2008-02-25 |
2023-08-12 |
rat |