| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Diana Cunha-Reis, Joaquim A Ribeiro, Ana M Sebastiã. A1 and A2A receptor activation by endogenous adenosine is required for VIP enhancement of K+ -evoked [3H]-GABA release from rat hippocampal nerve terminals. Neuroscience letters. vol 430. issue 3. 2008-05-13. PMID:18054436. |
since vip modulation of hippocampal synaptic transmission is dependent on the tonic actions of adenosine we investigated if endogenous adenosine could influence vip enhancement of gaba release from isolated hippocampal nerve endings, and which adenosine receptors could be mediating this influence. |
2008-05-13 |
2023-08-12 |
rat |
| Diana Cunha-Reis, Joaquim A Ribeiro, Ana M Sebastiã. A1 and A2A receptor activation by endogenous adenosine is required for VIP enhancement of K+ -evoked [3H]-GABA release from rat hippocampal nerve terminals. Neuroscience letters. vol 430. issue 3. 2008-05-13. PMID:18054436. |
in conclusion, the enhancement of gaba release caused by vip in hippocampal nerve terminals is dependent on the tonic actions of adenosine on both a(1) and a(2a) receptors, and this action of adenosine is essential to vip modulation of gaba release. |
2008-05-13 |
2023-08-12 |
rat |
| Neng Gong, Min Zhang, Xiao-Bing Zhang, Lin Chen, Guang-Chun Sun, Tian-Le X. The aspirin metabolite salicylate enhances neuronal excitation in rat hippocampal CA1 area through reducing GABAergic inhibition. Neuropharmacology. vol 54. issue 2. 2008-05-12. PMID:18078964. |
salicylate significantly inhibited the amplitudes of both evoked and miniature inhibitory postsynaptic currents, and directly reduced gamma-aminobutyric acid type a (gaba(a)) receptor-mediated responses in cultured rat hippocampal neurons. |
2008-05-12 |
2023-08-12 |
rat |
| Pirjo Saransaari, Simo S Oj. Characteristics of GABA release induced by free radicals in mouse hippocampal slices. Neurochemical research. vol 33. issue 3. 2008-05-06. PMID:17712630. |
characteristics of gaba release induced by free radicals in mouse hippocampal slices. |
2008-05-06 |
2023-08-12 |
mouse |
| Pirjo Saransaari, Simo S Oj. Characteristics of GABA release induced by free radicals in mouse hippocampal slices. Neurochemical research. vol 33. issue 3. 2008-05-06. PMID:17712630. |
the properties and regulation of preloaded [3h]gaba release from mouse hippocampal slices were now studied in free radical-containing medium in a superfusion system. |
2008-05-06 |
2023-08-12 |
mouse |
| Kati S Saarelainen, Martin Ranna, Holger Rabe, Saku T Sinkkonen, Tommi Möykkynen, Mikko Uusi-Oukari, Anni-Maija Linden, Hartmut Lüddens, Esa R Korp. Enhanced behavioral sensitivity to the competitive GABA agonist, gaboxadol, in transgenic mice over-expressing hippocampal extrasynaptic alpha6beta GABA(A) receptors. Journal of neurochemistry. vol 105. issue 2. 2008-05-06. PMID:18021290. |
enhanced behavioral sensitivity to the competitive gaba agonist, gaboxadol, in transgenic mice over-expressing hippocampal extrasynaptic alpha6beta gaba(a) receptors. |
2008-05-06 |
2023-08-12 |
mouse |
| Kati S Saarelainen, Martin Ranna, Holger Rabe, Saku T Sinkkonen, Tommi Möykkynen, Mikko Uusi-Oukari, Anni-Maija Linden, Hartmut Lüddens, Esa R Korp. Enhanced behavioral sensitivity to the competitive GABA agonist, gaboxadol, in transgenic mice over-expressing hippocampal extrasynaptic alpha6beta GABA(A) receptors. Journal of neurochemistry. vol 105. issue 2. 2008-05-06. PMID:18021290. |
we used a transgenic mouse line expressing the gaba(a) receptor alpha6 subunit gene in the forebrain under the thy-1.2 promoter (thy1alpha6) mice ectopically expressing alpha6 subunits especially in the hippocampus to study how extrasynaptically enriched alphabeta(gamma2)-type receptors alter animal behavior and receptor responses. |
2008-05-06 |
2023-08-12 |
mouse |
| Kati S Saarelainen, Martin Ranna, Holger Rabe, Saku T Sinkkonen, Tommi Möykkynen, Mikko Uusi-Oukari, Anni-Maija Linden, Hartmut Lüddens, Esa R Korp. Enhanced behavioral sensitivity to the competitive GABA agonist, gaboxadol, in transgenic mice over-expressing hippocampal extrasynaptic alpha6beta GABA(A) receptors. Journal of neurochemistry. vol 105. issue 2. 2008-05-06. PMID:18021290. |
in these mice extrasynaptic alpha6beta receptors make up about 10% of the hippocampal gaba(a) receptors resulting in imbalance between synaptic and extrasynaptic inhibition. |
2008-05-06 |
2023-08-12 |
mouse |
| Kati S Saarelainen, Martin Ranna, Holger Rabe, Saku T Sinkkonen, Tommi Möykkynen, Mikko Uusi-Oukari, Anni-Maija Linden, Hartmut Lüddens, Esa R Korp. Enhanced behavioral sensitivity to the competitive GABA agonist, gaboxadol, in transgenic mice over-expressing hippocampal extrasynaptic alpha6beta GABA(A) receptors. Journal of neurochemistry. vol 105. issue 2. 2008-05-06. PMID:18021290. |
in hippocampal sections of thy1alpha6 mice, the alpha6beta receptors could be visualized autoradiographically by interactions between gaboxadol and gaba via [(35)s]tbps binding to the gaba(a) receptor ionophore. |
2008-05-06 |
2023-08-12 |
mouse |
| Clotilde Mannoury la Cour, Chloé Herbelles, Valérie Pasteau, Guillaume de Nanteuil, Mark J Milla. Influence of positive allosteric modulators on GABA(B) receptor coupling in rat brain: a scintillation proximity assay characterisation of G protein subtypes. Journal of neurochemistry. vol 105. issue 2. 2008-05-06. PMID:18021295. |
similar findings were acquired in hippocampus and cerebellum, and the gaba(b) antagonist, cgp55845a, abolished agonist-induced activation of galphao and galphai(1/3) in all structures. |
2008-05-06 |
2023-08-12 |
human |
| Wei Xie, Chang-zheng Li, Yong Bao, Li-jian Y. [Saikosaponins inhibit increased glutamate and GABA expressions in the hippocampus of pentetrazole-induced slow kindling rats]. Nan fang yi ke da xue xue bao = Journal of Southern Medical University. vol 26. issue 8. 2008-05-05. PMID:16939901. |
[saikosaponins inhibit increased glutamate and gaba expressions in the hippocampus of pentetrazole-induced slow kindling rats]. |
2008-05-05 |
2023-08-12 |
rat |
| Wei Xie, Chang-zheng Li, Yong Bao, Li-jian Y. [Saikosaponins inhibit increased glutamate and GABA expressions in the hippocampus of pentetrazole-induced slow kindling rats]. Nan fang yi ke da xue xue bao = Journal of Southern Medical University. vol 26. issue 8. 2008-05-05. PMID:16939901. |
on glutamate and gaba expressions in the hippocampus of slow kindling rats induced by pentetrazole. |
2008-05-05 |
2023-08-12 |
rat |
| Jacob McClean, Joseph L Nuñe. 17alpha-Estradiol is neuroprotective in male and female rats in a model of early brain injury. Experimental neurology. vol 210. issue 1. 2008-05-02. PMID:17997403. |
we observed that treatment with 17alpha-estradiol significantly attenuates the gaba(a) receptor-induced reduction in hippocampal volume and impaired hippocampal-dependent performance on the morris water maze and radial arm maze. |
2008-05-02 |
2023-08-12 |
human |
| Jacob McClean, Joseph L Nuñe. 17alpha-Estradiol is neuroprotective in male and female rats in a model of early brain injury. Experimental neurology. vol 210. issue 1. 2008-05-02. PMID:17997403. |
17alpha-estradiol-mediated neuroprotection is hypothesized to be achieved by attenuating gaba(a) receptor-induced cell loss, assessed in primary hippocampal cultures using both the lactate dehydrogenase assay and tunel, with equivalent prevention of cell loss in the presence or absence of the estrogen receptor antagonist, ici-182,780. |
2008-05-02 |
2023-08-12 |
human |
| Alfred Meurs, Ralph Clinckers, Guy Ebinger, Yvette Michotte, Ilse Smolder. Seizure activity and changes in hippocampal extracellular glutamate, GABA, dopamine and serotonin. Epilepsy research. vol 78. issue 1. 2008-05-02. PMID:18054462. |
seizure activity and changes in hippocampal extracellular glutamate, gaba, dopamine and serotonin. |
2008-05-02 |
2023-08-12 |
human |
| Alfred Meurs, Ralph Clinckers, Guy Ebinger, Yvette Michotte, Ilse Smolder. Seizure activity and changes in hippocampal extracellular glutamate, GABA, dopamine and serotonin. Epilepsy research. vol 78. issue 1. 2008-05-02. PMID:18054462. |
our aim was to better characterise the relationship between seizure activity and changes in hippocampal glutamate, gaba, dopamine and serotonin by comparing three limbic seizure models which differ only in the pharmacological mechanism used to induce seizures. |
2008-05-02 |
2023-08-12 |
human |
| Alfred Meurs, Ralph Clinckers, Guy Ebinger, Yvette Michotte, Ilse Smolder. Seizure activity and changes in hippocampal extracellular glutamate, GABA, dopamine and serotonin. Epilepsy research. vol 78. issue 1. 2008-05-02. PMID:18054462. |
seizure-related behavioural changes were scored and hippocampal extracellular glutamate, gaba, dopamine and serotonin concentrations were monitored. |
2008-05-02 |
2023-08-12 |
human |
| Alfred Meurs, Ralph Clinckers, Guy Ebinger, Yvette Michotte, Ilse Smolder. Seizure activity and changes in hippocampal extracellular glutamate, GABA, dopamine and serotonin. Epilepsy research. vol 78. issue 1. 2008-05-02. PMID:18054462. |
during seizures, hippocampal glutamate, gaba and dopamine concentrations increased in all groups. |
2008-05-02 |
2023-08-12 |
human |
| Alfred Meurs, Ralph Clinckers, Guy Ebinger, Yvette Michotte, Ilse Smolder. Seizure activity and changes in hippocampal extracellular glutamate, GABA, dopamine and serotonin. Epilepsy research. vol 78. issue 1. 2008-05-02. PMID:18054462. |
our results suggest a direct relationship between seizure activity and increased hippocampal extracellular concentrations of glutamate, gaba and dopamine, but not serotonin. |
2008-05-02 |
2023-08-12 |
human |
| A R McQuisto. Layer selective presynaptic modulation of excitatory inputs to hippocampal cornu Ammon 1 by mu-opioid receptor activation. Neuroscience. vol 151. issue 1. 2008-04-22. PMID:18065149. |
therefore, we used voltage-sensitive dye imaging, whole cell patch clamping, photolysis of alpha-carboxy-2-nitrobenzyl ester, trifluoroacetic acid salt (cnb) -caged gaba, and micro-sectioned slices of rat hippocampus to investigate the effect of mor activation in ca1. |
2008-04-22 |
2023-08-12 |
rat |