| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jacek R Wiśniewski, Alexandre Zougman, Matthias Man. Combination of FASP and StageTip-based fractionation allows in-depth analysis of the hippocampal membrane proteome. Journal of proteome research. vol 8. issue 12. 2010-03-02. PMID:19848406. |
this data set covers 83% of glutamate and gaba receptor subunits identified in hippocampus in the allen brain atlas and adds further isoforms. |
2010-03-02 |
2023-08-12 |
mouse |
| M I Naseer, H Y Lee, N Ullah, I Ullah, M S Park, S H Kim, M O Ki. Ethanol and PTZ effects on siRNA-mediated GABAB1 receptor: down regulation of intracellular signaling pathway in prenatal rat cortical and hippocampal neurons. Synapse (New York, N.Y.). vol 64. issue 3. 2010-03-02. PMID:19862689. |
the present study was undertaken to explore the downstream signaling and role of gaba(b1)r upon acute ethanol and pentylenetetrazol (ptz) exposure for (20 min) in cortical and hippocampal neuronal cell cultures by using gaba(b1)r rna interference (i) (30 nm, 48 h) at gestational days 17.5. |
2010-03-02 |
2023-08-12 |
rat |
| M I Naseer, H Y Lee, N Ullah, I Ullah, M S Park, S H Kim, M O Ki. Ethanol and PTZ effects on siRNA-mediated GABAB1 receptor: down regulation of intracellular signaling pathway in prenatal rat cortical and hippocampal neurons. Synapse (New York, N.Y.). vol 64. issue 3. 2010-03-02. PMID:19862689. |
the results showed that gaba(b1)r and protein kinase a-alpha (pka) showed decreased expression upon ethanol and ptz exposure in cortical and hippocampal neurons during transfected and nontransfected conditions, whereas these effects could lead to significant changes in phosphorylation of camp-response element binding protein (p-creb) expression where gaba(b1)r was knocked down. |
2010-03-02 |
2023-08-12 |
rat |
| Li-Rong Shao, F Edward Dude. Both synaptic and intrinsic mechanisms underlie the different properties of population bursts in the hippocampal CA3 area of immature versus adult rats. The Journal of physiology. vol 587. issue Pt 24. 2010-02-26. PMID:19884320. |
pharmacological blockade of gaba(a) receptors on ca3 pyramidal cells in hippocampal slices from immature rats (i.e. |
2010-02-26 |
2023-08-12 |
rat |
| Marco Rohde, Tursonjan Tokay, Rüdiger Köhling, Timo Kirschstei. GABA(A) receptor inhibition does not affect mGluR-dependent LTD at hippocampal Schaffer collateral-CA1 synapses. Neuroscience letters. vol 467. issue 1. 2010-02-25. PMID:19800390. |
gaba(a) receptor inhibition does not affect mglur-dependent ltd at hippocampal schaffer collateral-ca1 synapses. |
2010-02-25 |
2023-08-12 |
rat |
| Marco Rohde, Tursonjan Tokay, Rüdiger Köhling, Timo Kirschstei. GABA(A) receptor inhibition does not affect mGluR-dependent LTD at hippocampal Schaffer collateral-CA1 synapses. Neuroscience letters. vol 467. issue 1. 2010-02-25. PMID:19800390. |
here, we used field potential recordings of the schaffer collateral-ca1 synapses in rat hippocampal slices in order to study the effect of gaba(a) receptor (gaba(a)r) inhibition on mglur-dependent long-term depression (ltd). |
2010-02-25 |
2023-08-12 |
rat |
| Francine M Bene. Amygdalocortical circuitry in schizophrenia: from circuits to molecules. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 35. issue 1. 2010-02-24. PMID:19727065. |
for example, single-cell recordings in hippocampal slices exposed to increased activation from the bla have shown decreases in gaba currents in pyramidal neurons in so of ca3/2, but not ca1, and support the validity of this model. |
2010-02-24 |
2023-08-12 |
Not clear |
| Harald Hentschke, Claudia Benkwitz, Matthew I Banks, Mark G Perkins, Gregg E Homanics, Robert A Pearc. Altered GABAA,slow inhibition and network oscillations in mice lacking the GABAA receptor beta3 subunit. Journal of neurophysiology. vol 102. issue 6. 2010-02-22. PMID:19846622. |
phasic gabaergic inhibition in hippocampus and neocortex falls into two kinetically distinct categories, gaba(a,fast) and gaba(a,slow). |
2010-02-22 |
2023-08-12 |
mouse |
| Harald Hentschke, Claudia Benkwitz, Matthew I Banks, Mark G Perkins, Gregg E Homanics, Robert A Pearc. Altered GABAA,slow inhibition and network oscillations in mice lacking the GABAA receptor beta3 subunit. Journal of neurophysiology. vol 102. issue 6. 2010-02-22. PMID:19846622. |
in hippocampal area ca1, gaba(a,fast) is generally believed to underlie gamma oscillations, whereas the contribution of gaba(a,slow) to hippocampal rhythms has been speculative. |
2010-02-22 |
2023-08-12 |
mouse |
| Harald Hentschke, Claudia Benkwitz, Matthew I Banks, Mark G Perkins, Gregg E Homanics, Robert A Pearc. Altered GABAA,slow inhibition and network oscillations in mice lacking the GABAA receptor beta3 subunit. Journal of neurophysiology. vol 102. issue 6. 2010-02-22. PMID:19846622. |
with the caveat that seizure-induced changes in inhibitory circuits might have contributed to the changes observed in the mutant animals, our results point to a strong contribution of beta(3) subunits to slow gabaergic inhibition onto pyramidal neurons but not onto gaba(a,fast) -producing interneurons and support different roles for these slow inhibitory synapses in the generation and coordination of hippocampal network rhythms. |
2010-02-22 |
2023-08-12 |
mouse |
| I Marchionni, Z Kasap, J W Mozrzymas, W Sieghart, E Cherubini, P Zacch. New insights on the role of gephyrin in regulating both phasic and tonic GABAergic inhibition in rat hippocampal neurons in culture. Neuroscience. vol 164. issue 2. 2010-02-12. PMID:19660531. |
when expressed in cultured rat hippocampal neurons as a fusion protein containing a nuclear localization signal, scfv-gephyrin were able to remove endogenous gephyrin from gaba(a) receptor clusters. |
2010-02-12 |
2023-08-12 |
rat |
| H Haghir, S Kovac, E-J Speckmann, K Zilles, A Gorj. Patterns of neurotransmitter receptor distributions following cortical spreading depression. Neuroscience. vol 163. issue 4. 2010-02-12. PMID:19665048. |
in addition to up-regulation of ionotropic glutamate receptors, receptor binding sites of gaba(a), muscarinic m1 and m2, adrenergic alpha(1) and alpha(2), and serotonergic 5-ht(2) receptors were increased in the hippocampus. |
2010-02-12 |
2023-08-12 |
rat |
| Y Wang, T Kakizaki, H Sakagami, K Saito, S Ebihara, M Kato, M Hirabayashi, Y Saito, N Furuya, Y Yanagaw. Fluorescent labeling of both GABAergic and glycinergic neurons in vesicular GABA transporter (VGAT)-venus transgenic mouse. Neuroscience. vol 164. issue 3. 2010-02-08. PMID:19766173. |
double immunostaining analysis in line #39 mouse showed that venus-expressing cells are primarily immunoreactive for gaba in cerebral cortex, hippocampus and cerebellar cortex and for gaba or glycine in dorsal cochlear nucleus. |
2010-02-08 |
2023-08-12 |
mouse |
| Giana P Cognato, Paula M Agostinho, Jörg Hockemeyer, Christa E Müller, Diogo O Souza, Rodrigo A Cunh. Caffeine and an adenosine A(2A) receptor antagonist prevent memory impairment and synaptotoxicity in adult rats triggered by a convulsive episode in early life. Journal of neurochemistry. vol 112. issue 2. 2010-02-05. PMID:19878534. |
in accordance with the relationship between synaptotoxicity and memory dysfunction, the hippocampus of these adult rats treated with kainate at p7 displayed a lower density of synaptic proteins such as snap-25 and syntaxin (but not synaptophysin), as well as vesicular glutamate transporters type 1 (but not vesicular gaba transporters), with no changes in psd-95, nmda receptor subunits (nr1, nr2a, nr2b) or alpha-amino-3-hydroxy-5-methylisoxazole-4-propionate receptor subunits (glur1, glur2) compared with controls. |
2010-02-05 |
2023-08-12 |
rat |
| Laura Lagostena, Marcelo Rosato-Siri, Mara D'Onofrio, Rossella Brandi, Ivan Arisi, Simona Capsoni, Jessica Franzot, Antonino Cattaneo, Enrico Cherubin. In the adult hippocampus, chronic nerve growth factor deprivation shifts GABAergic signaling from the hyperpolarizing to the depolarizing direction. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 30. issue 3. 2010-02-05. PMID:20089897. |
thus, in hippocampal slices obtained from 6-month-old ad11 (but not wild-type) mice, the gaba(a) agonist isoguvacine significantly increased the firing of ca1 principal cells and, at the network level, the frequency of multiunit activity recorded with extracellular electrodes. |
2010-02-05 |
2023-08-12 |
mouse |
| Rebekah L Fleming, Paul B Manis, A Leslie Morro. The effects of acute and chronic ethanol exposure on presynaptic and postsynaptic gamma-aminobutyric acid (GABA) neurotransmission in cultured cortical and hippocampal neurons. Alcohol (Fayetteville, N.Y.). vol 43. issue 8. 2010-01-27. PMID:20004338. |
the effects of acute and chronic ethanol exposure on presynaptic and postsynaptic gamma-aminobutyric acid (gaba) neurotransmission in cultured cortical and hippocampal neurons. |
2010-01-27 |
2023-08-12 |
Not clear |
| Rebekah L Fleming, Paul B Manis, A Leslie Morro. The effects of acute and chronic ethanol exposure on presynaptic and postsynaptic gamma-aminobutyric acid (GABA) neurotransmission in cultured cortical and hippocampal neurons. Alcohol (Fayetteville, N.Y.). vol 43. issue 8. 2010-01-27. PMID:20004338. |
we have used in vitro ethanol exposure followed by recording of miniature inhibitory postsynaptic currents (mipscs) to determine whether acute or chronic ethanol exposure directly alters synaptic gaba(a) receptor (gaba(a)r) function or gaba release in cultured cortical and hippocampal neurons. |
2010-01-27 |
2023-08-12 |
Not clear |
| Rebekah L Fleming, Paul B Manis, A Leslie Morro. The effects of acute and chronic ethanol exposure on presynaptic and postsynaptic gamma-aminobutyric acid (GABA) neurotransmission in cultured cortical and hippocampal neurons. Alcohol (Fayetteville, N.Y.). vol 43. issue 8. 2010-01-27. PMID:20004338. |
the results suggest that ethanol exposure in vitro has limited effects on synaptic gaba(a)r function and action potential-independent gaba release in cultured neurons and that ethanol exposure in cultured cortical and hippocampal neurons may not reproduce all the effects that occur in vivo and in acute brain slices. |
2010-01-27 |
2023-08-12 |
Not clear |
| Neng Gong, Yong Li, Guo-Qiang Cai, Rui-Fang Niu, Qi Fang, Kun Wu, Zhong Chen, Long-Nian Lin, Lin Xu, Jian Fei, Tian-Le X. GABA transporter-1 activity modulates hippocampal theta oscillation and theta burst stimulation-induced long-term potentiation. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 29. issue 50. 2010-01-26. PMID:20016099. |
gaba transporter-1 activity modulates hippocampal theta oscillation and theta burst stimulation-induced long-term potentiation. |
2010-01-26 |
2023-08-12 |
mouse |
| Neng Gong, Yong Li, Guo-Qiang Cai, Rui-Fang Niu, Qi Fang, Kun Wu, Zhong Chen, Long-Nian Lin, Lin Xu, Jian Fei, Tian-Le X. GABA transporter-1 activity modulates hippocampal theta oscillation and theta burst stimulation-induced long-term potentiation. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 29. issue 50. 2010-01-26. PMID:20016099. |
here we show that in the ca1 region of mouse hippocampus, pharmacological blockade or genetic deletion of gaba transporter-1 (gat1) specifically impaired long-term potentiation (ltp) induced by theta burst stimulation, but had no effect on ltp induced by high-frequency stimulation or long-term depression induced by low-frequency stimulation. |
2010-01-26 |
2023-08-12 |
mouse |