| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Emily M Stanley, Marlene A Wilson, Jim R Fade. Hippocampal neurotransmitter efflux during one-trial novel object recognition in rats. Neuroscience letters. vol 511. issue 1. 2012-07-27. PMID:22306091. |
here we used a one-trial object recognition paradigm paired with in vivo microdialysis to assess hippocampal acetylcholine (ach), glutamate and gaba efflux when rats were exposed to familiar objects, and when given the option to explore familiar and novel objects. |
2012-07-27 |
2023-08-12 |
rat |
| Emily M Stanley, Marlene A Wilson, Jim R Fade. Hippocampal neurotransmitter efflux during one-trial novel object recognition in rats. Neuroscience letters. vol 511. issue 1. 2012-07-27. PMID:22306091. |
regardless of object familiarity, object exploration was accompanied by an increase in hippocampal ach efflux, while gaba efflux was unaffected. |
2012-07-27 |
2023-08-12 |
rat |
| Slavica Krantic, Nathalie Isorce, Naguib Mechawar, Maria Antonietta Davoli, Erika Vignault, Marilia Albuquerque, Jean-Guy Chabot, Emmanuel Moyse, Jean-Pierre Chauvin, Isabelle Aubert, Joanne McLaurin, Rémi Quirio. Hippocampal GABAergic neurons are susceptible to amyloid-β toxicity in vitro and are decreased in number in the Alzheimer's disease TgCRND8 mouse model. Journal of Alzheimer's disease : JAD. vol 29. issue 2. 2012-07-26. PMID:22232004. |
in the tgcrnd8 mouse model of ad, we found a significant decrease in the number of hippocampal neurons immunoreactive for glutamate decarboxylase 67 (gad67), the enzyme synthesizing gaba. |
2012-07-26 |
2023-08-12 |
mouse |
| Günther Sperk, Anna Wieselthaler-Hölzl, Susanne Pirker, Ramon Tasan, Sarah S Strasser, Meinrad Drexel, Christian Pifl, Julian Marschalek, Martin Ortler, Eugen Trinka, Katja Heitmair-Wietzorrek, Philippe Ciofi, Martha Feucht, Christoph Baumgartner, Thomas Czec. Glutamate decarboxylase 67 is expressed in hippocampal mossy fibers of temporal lobe epilepsy patients. Hippocampus. vol 22. issue 3. 2012-07-23. PMID:21509853. |
recently, expression of glutamate decarboxylase-67 (gad67), a key enzyme of gaba synthesis, was detected in the otherwise glutamatergic mossy fibers of the rat hippocampus. |
2012-07-23 |
2023-08-12 |
rat |
| Günther Sperk, Anna Wieselthaler-Hölzl, Susanne Pirker, Ramon Tasan, Sarah S Strasser, Meinrad Drexel, Christian Pifl, Julian Marschalek, Martin Ortler, Eugen Trinka, Katja Heitmair-Wietzorrek, Philippe Ciofi, Martha Feucht, Christoph Baumgartner, Thomas Czec. Glutamate decarboxylase 67 is expressed in hippocampal mossy fibers of temporal lobe epilepsy patients. Hippocampus. vol 22. issue 3. 2012-07-23. PMID:21509853. |
provided that the strong expression of gad67 results in synthesis of gaba in hippocampal mossy fibers this may represent a self-protecting mechanism in tle. |
2012-07-23 |
2023-08-12 |
rat |
| Maria Śmiałowska, Krystyna Gołembiowska, Małgorzata Kajta, Barbara Zięba, Anna Dziubina, Helena Domi. Selective mGluR1 antagonist EMQMCM inhibits the kainate-induced excitotoxicity in primary neuronal cultures and in the rat hippocampus. Neurotoxicity research. vol 21. issue 4. 2012-07-23. PMID:22144346. |
in vivo microdialysis studies in rat hippocampus showed that emqmcm (100 μm) significantly increased γ-aminobutyric acid (gaba) and decreased glutamate release. |
2012-07-23 |
2023-08-12 |
mouse |
| Eva Martisova, Maite Solas, Igor Horrillo, Jorge E Ortega, J Javier Meana, Rosa María Tordera, María Javier Ramíre. Long lasting effects of early-life stress on glutamatergic/GABAergic circuitry in the rat hippocampus. Neuropharmacology. vol 62. issue 5-6. 2012-07-23. PMID:22245561. |
aged ms rats showed a downregulation of vesicular glutamate transporter 1 and 2 (vglut1 and vglut2) and gaba transporter (vgat) and increased expression of excitatory amino acid transporter 2 (eaat2) in the hippocampus. |
2012-07-23 |
2023-08-12 |
rat |
| Eva Martisova, Maite Solas, Igor Horrillo, Jorge E Ortega, J Javier Meana, Rosa María Tordera, María Javier Ramíre. Long lasting effects of early-life stress on glutamatergic/GABAergic circuitry in the rat hippocampus. Neuropharmacology. vol 62. issue 5-6. 2012-07-23. PMID:22245561. |
corticosterone induced an increase glutamate and a decrease in gaba release in hippocampal slices, which was reversed by venlafaxine. |
2012-07-23 |
2023-08-12 |
rat |
| Alejandro Higuera-Matas, Miguel Miguéns, Santiago M Coria, María Amparo Assis, Erika Borcel, Nuria del Olmo, Emilio Ambrosi. Sex-specific disturbances of the glutamate/GABA balance in the hippocampus of adult rats subjected to adolescent cannabinoid exposure. Neuropharmacology. vol 62. issue 5-6. 2012-07-23. PMID:22245681. |
here we show that k(+)-induced γ-amino butyric acid (gaba) release increases in the ca1 hippocampal field of wistar rats of both sexes that were treated chronically with the cannabinoid agonist cp 55,940 (cp55940) during adolescence. |
2012-07-23 |
2023-08-12 |
rat |
| Dong Hyun Kim, Jong Min Kim, Se Jin Park, Seungheon Lee, Chan Young Shin, Jae Hoon Cheong, Jong Hoon Ry. Hippocampal extracellular signal-regulated kinase signaling has a role in passive avoidance memory retrieval induced by GABAA Receptor modulation in mice. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 37. issue 5. 2012-07-20. PMID:22169949. |
we conducted one-trial passive avoidance task with pre-retention trial drug administration in the hippocampus to test the effects of gaba(a) receptor modulation on memory retrieval. |
2012-07-20 |
2023-08-12 |
mouse |
| Dong Hyun Kim, Jong Min Kim, Se Jin Park, Seungheon Lee, Chan Young Shin, Jae Hoon Cheong, Jong Hoon Ry. Hippocampal extracellular signal-regulated kinase signaling has a role in passive avoidance memory retrieval induced by GABAA Receptor modulation in mice. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 37. issue 5. 2012-07-20. PMID:22169949. |
accordingly, to investigate whether gaba(a) receptor activation or inhibition induces erk phosphorylation during memory retrieval, drugs that target the gaba(a) receptor were administered into the hippocampus before the retention trial. |
2012-07-20 |
2023-08-12 |
mouse |
| Marcin Szczot, Marta Magdalena Czyzewska, Giovanni Appendino, Jerzy Wladyslaw Mozrzyma. Modulation of GABAergic synaptic currents and current responses by α-thujone and dihydroumbellulone. Journal of natural products. vol 75. issue 4. 2012-07-20. PMID:22364543. |
to address these issues, cultured hippocampal neurons were used to investigate the action of 1a on gabaergic miniature inhibitory postsynaptic currents (mipscs) and on responses to exogenous gaba applications. |
2012-07-20 |
2023-08-12 |
Not clear |
| Jean-Baptiste Drouet, Florence Fauvelle, Cécile Batandier, André Peinnequin, Antonia Alonso, Nadine Fidier, Renaud Maury, Laurent Poulet, Alain Buguet, Raymond Cespuglio, Frédéric Canin. Metyrapone effects on systemic and cerebral energy metabolism. European journal of pharmacology. vol 682. issue 1-3. 2012-07-17. PMID:22387859. |
in the hippocampus, metyrapone decreased γ-aminobutyric acid (gaba) and glutamate levels but increased glutamine and n-acetyl-aspartate contents (naa). |
2012-07-17 |
2023-08-12 |
rat |
| R A Mohamed, A M Agha, N N Nassa. SCH58261 the selective adenosine A(2A) receptor blocker modulates ischemia reperfusion injury following bilateral carotid occlusion: role of inflammatory mediators. Neurochemical research. vol 37. issue 3. 2012-06-29. PMID:22071908. |
ir increased hippocampal glutamate (glu), gaba, glycine (gly) and aspartate (asp). |
2012-06-29 |
2023-08-12 |
rat |
| Patricia Salazar, Ricardo Tapi. Allopregnanolone potentiates the glutamate-mediated seizures induced by 4-aminopyridine in rat hippocampus in vivo. Neurochemical research. vol 37. issue 3. 2012-06-29. PMID:22081320. |
we previously found that in rat hippocampal slices allopregnanolone (3α-hydroxy-5α-pregnan-20-one), a positive gaba(a) receptor modulator, suppresses the epileptic discharges induced by 4-aminopyridine (4-ap), a convulsant k(+) channel blocker that stimulates glutamate release. |
2012-06-29 |
2023-08-12 |
rat |
| Patricia Salazar, Ricardo Tapi. Allopregnanolone potentiates the glutamate-mediated seizures induced by 4-aminopyridine in rat hippocampus in vivo. Neurochemical research. vol 37. issue 3. 2012-06-29. PMID:22081320. |
extracellular levels of aspartate, glutamate and gaba were analyzed by hplc in the microdialysis fractions, and 24 h after the experiment the hippocampus was studied histologically. |
2012-06-29 |
2023-08-12 |
rat |
| Erik Keimpema, Alex Straiker, Ken Mackie, Tibor Harkany, Jens Hjerling-Leffle. Sticking out of the crowd: the molecular identity and development of cholecystokinin-containing basket cells. The Journal of physiology. vol 590. issue 4. 2012-06-26. PMID:22219340. |
certain essential cognitive processes require the precise temporal interplay between glutamatergic (excitatory) pyramidal cells and γ-aminobutyric acid (gaba)-releasing inhibitory interneurons in the hippocampus. |
2012-06-26 |
2023-08-12 |
Not clear |
| Jae-Wook Kim, Chung-Soo Kim, Zhenzhen Hu, Jin-Yi Han, Si Kwan Kim, Sung-Kwang Yoo, Yeong Man Yeo, Myong Soo Chong, Kinam Lee, Jin Tae Hong, Ki-Wan O. Enhancement of pentobarbital-induced sleep by apigenin through chloride ion channel activation. Archives of pharmacal research. vol 35. issue 2. 2012-06-26. PMID:22370792. |
apigenin increased glutamate decarboxylase (gad) and had no effect on the expression of gaba(a) receptor α-, β-, γ-subunits in n hippocampus of mouse brain, showing different expression of subunits from pentobarbital treatment group. |
2012-06-26 |
2023-08-12 |
mouse |
| Xiaoyuan Mao, Changwei Ji, Chunyan Sun, Danfeng Cao, Ping Ma, Zhong Ji, Fangyuan Cao, Dongyu Min, Shuzhi Li, Jiqun Cai, Yonggang Ca. Topiramate attenuates cerebral ischemia/reperfusion injury in gerbils via activating GABAergic signaling and inhibiting astrogliosis. Neurochemistry international. vol 60. issue 1. 2012-06-20. PMID:22085431. |
besides, treatment with tpm also resulted in the increased protein expressions of gaba(a)r α1, gaba(a)r γ2 and kcc2 together with the decreased protein level of nkcc1 in gerbils hippocampus. |
2012-06-20 |
2023-08-12 |
Not clear |
| Pascale P Quilichini, Michel Le Van Quyen, Anton Ivanov, Dennis A Turner, Aurélie Carabalona, Henri Gozlan, Monique Esclapez, Christophe Bernar. Hub GABA neurons mediate gamma-frequency oscillations at ictal-like event onset in the immature hippocampus. Neuron. vol 74. issue 1. 2012-06-19. PMID:22500630. |
hub gaba neurons mediate gamma-frequency oscillations at ictal-like event onset in the immature hippocampus. |
2012-06-19 |
2023-08-12 |
Not clear |