| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Tyler K Best, Nathan P Cramer, Lina Chakrabarti, Tarik F Haydar, Zygmunt Galdzick. Dysfunctional hippocampal inhibition in the Ts65Dn mouse model of Down syndrome. Experimental neurology. vol 233. issue 2. 2012-03-26. PMID:22178330. |
however, the gaba(b)/gaba(a) ratios evoked by stimulation within the slm of ts65dn hippocampus were significantly larger in magnitude, consistent with increased gaba(b)/girk currents after slm stimulation. |
2012-03-26 |
2023-08-12 |
mouse |
| Bo-Eun Yoon, Seonmi Jo, Junsung Woo, Jae-Hoon Lee, Taekeun Kim, Daesoo Kim, C Justin Le. The amount of astrocytic GABA positively correlates with the degree of tonic inhibition in hippocampal CA1 and cerebellum. Molecular brain. vol 4. 2012-03-19. PMID:22107761. |
in this study, we screened for the presence of astrocytic gaba in various brain regions such as hippocampus, thalamus, hypothalamus and cerebellum using immunohistochemistry. |
2012-03-19 |
2023-08-12 |
Not clear |
| Bo-Eun Yoon, Seonmi Jo, Junsung Woo, Jae-Hoon Lee, Taekeun Kim, Daesoo Kim, C Justin Le. The amount of astrocytic GABA positively correlates with the degree of tonic inhibition in hippocampal CA1 and cerebellum. Molecular brain. vol 4. 2012-03-19. PMID:22107761. |
unlike cerebellar glial cells, hippocampal astrocytes did not contain gaba. |
2012-03-19 |
2023-08-12 |
Not clear |
| Laura Dazzi, Alessandra Matzeu, Giovanni Biggi. Role of ionotropic glutamate receptors in the regulation of hippocampal norepinephrine output in vivo. Brain research. vol 1386. 2012-03-12. PMID:21362410. |
the gaba(a) receptor antagonist bicuculline (10μm) prevented the decrease in hippocampal norepinephrine output induced by either nmda or 10μm ampa. |
2012-03-12 |
2023-08-12 |
rat |
| Yanmei Wang, Lixuan Zhan, Wei Zeng, Ke Li, Weiwen Sun, Zao C Xu, En X. Downregulation of hippocampal GABA after hypoxia-induced seizures in neonatal rats. Neurochemical research. vol 36. issue 12. 2012-03-12. PMID:21833845. |
downregulation of hippocampal gaba after hypoxia-induced seizures in neonatal rats. |
2012-03-12 |
2023-08-12 |
rat |
| Yanmei Wang, Lixuan Zhan, Wei Zeng, Ke Li, Weiwen Sun, Zao C Xu, En X. Downregulation of hippocampal GABA after hypoxia-induced seizures in neonatal rats. Neurochemical research. vol 36. issue 12. 2012-03-12. PMID:21833845. |
our study indicates that downregulation of hippocampal gaba after hypoxia-induced seizures in neonatal rats may contribute to higher epileptic susceptibility in later life. |
2012-03-12 |
2023-08-12 |
rat |
| Shane A Perrine, Shonagh K O'Leary-Moore, Matthew P Galloway, John H Hannigan, Scott E Bowe. Binge toluene exposure alters glutamate, glutamine and GABA in the adolescent rat brain as measured by proton magnetic resonance spectroscopy. Drug and alcohol dependence. vol 115. issue 1-2. 2012-03-07. PMID:21126832. |
adolescent male sprague-dawley rats were exposed to toluene (0, 8000, or 12,000 ppm) for 15 min twice daily from postnatal day 28 (p28) through p34 and then euthanized either 1 or 7 days later (on p35 or p42) to assess glutamate (glu), glutamine, and gaba levels in intact tissue punches from the medial prefrontal cortex (mpfc), anterior striatum and hippocampus. |
2012-03-07 |
2023-08-12 |
rat |
| Shane A Perrine, Shonagh K O'Leary-Moore, Matthew P Galloway, John H Hannigan, Scott E Bowe. Binge toluene exposure alters glutamate, glutamine and GABA in the adolescent rat brain as measured by proton magnetic resonance spectroscopy. Drug and alcohol dependence. vol 115. issue 1-2. 2012-03-07. PMID:21126832. |
in the hippocampus, neither gaba nor glu was altered 1 day after exposure, whereas 7 days after exposure, increases were observed in gaba and glu. |
2012-03-07 |
2023-08-12 |
rat |
| Sang-Hun Lee, Ivan Soltes. Requirement for CB1 but not GABAB receptors in the cholecystokinin mediated inhibition of GABA release from cholecystokinin expressing basket cells. The Journal of physiology. vol 589. issue Pt 4. 2012-03-06. PMID:21173082. |
recently, cck was shown to act as a molecular switch for perisomatic inhibition in the hippocampus, by directly depolarizing parvalbumin expressing (pv+) basket cells while indirectly depressing gaba release from cck expressing (cck+) basket cells. |
2012-03-06 |
2023-08-12 |
rat |
| Kwang-Soon Park, Jin-Yi Han, Dong-Cheul Moon, Jin Tae Hong, Ki-Wan O. (-)-epigallocatechin-3-O-gallate augments pentobarbital-induced sleeping behaviors through Cl- channel activation. Journal of medicinal food. vol 14. issue 11. 2012-03-01. PMID:21883003. |
egcg and pentobarbital decreased gaba(a) receptors α-subunit expression and had no effect on the expression of β- and γ-subunits and of glutamic acid decarboxylase in the hippocampus of rats. |
2012-03-01 |
2023-08-12 |
mouse |
| Ahmad A Khundakar, Tyra S C Zetterströ. Effects of GABAB ligands alone and in combination with paroxetine on hippocampal BDNF gene expression. European journal of pharmacology. vol 671. issue 1-3. 2012-03-01. PMID:21930121. |
the inhibitory effect of baclofen on hippocampal bdnf mrna expression was significantly attenuated by pre-treatment the selective gaba(b) antagonists, cgp 46381 and cgp 55845 (10mg/kg, i.p.). |
2012-03-01 |
2023-08-12 |
rat |
| Ahmad A Khundakar, Tyra S C Zetterströ. Effects of GABAB ligands alone and in combination with paroxetine on hippocampal BDNF gene expression. European journal of pharmacology. vol 671. issue 1-3. 2012-03-01. PMID:21930121. |
our findings suggest a role for gaba(b), but not gaba(a), receptor-mediated mechanisms in the inhibitory regulation of basal hippocampal bdnf gene expression. |
2012-03-01 |
2023-08-12 |
rat |
| Ahmad A Khundakar, Tyra S C Zetterströ. Effects of GABAB ligands alone and in combination with paroxetine on hippocampal BDNF gene expression. European journal of pharmacology. vol 671. issue 1-3. 2012-03-01. PMID:21930121. |
our results indicate that gaba(b) receptor activation may play a role in the antidepressant drug-induced inhibition of bdnf gene expression in the hippocampus. |
2012-03-01 |
2023-08-12 |
rat |
| Po-Han Chiang, Pu-Yeh Wu, Tzu-Wei Kuo, Yu-Chao Liu, Chu-Fang Chan, Ta-Chun Chien, Jen-Kun Cheng, Yu-Yin Huang, Cheng-Di Chiu, Cheng-Chang Lie. GABA is depolarizing in hippocampal dentate granule cells of the adolescent and adult rats. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 32. issue 1. 2012-02-22. PMID:22219270. |
gaba is depolarizing in hippocampal dentate granule cells of the adolescent and adult rats. |
2012-02-22 |
2023-08-12 |
rat |
| Yi Shen, A Kerstin Lindemeyer, Claudia Gonzalez, Xuesi M Shao, Igor Spigelman, Richard W Olsen, Jing Lian. Dihydromyricetin as a novel anti-alcohol intoxication medication. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 32. issue 1. 2012-02-22. PMID:22219299. |
at the cellular levels, dhm (1 μm) antagonized both acute etoh-induced potentiation of gaba(a)rs and etoh exposure/withdrawal-induced gaba(a)r plasticity, including alterations in responsiveness of extrasynaptic and postsynaptic gaba(a)rs to acute etoh and, most importantly, increases in gaba(a)r α4 subunit expression in hippocampus and cultured neurons. |
2012-02-22 |
2023-08-12 |
rat |
| Hans-Michael Maric, Jayanta Mukherjee, Verena Tretter, Stephen J Moss, Hermann Schindeli. Gephyrin-mediated γ-aminobutyric acid type A and glycine receptor clustering relies on a common binding site. The Journal of biological chemistry. vol 286. issue 49. 2012-02-21. PMID:22006921. |
consistent with the biochemical data, mutations of the corresponding residues within the cytoplasmic domain of α2 subunit-containing gaba(a)rs attenuated clustering of these receptors at postsynaptic sites in hippocampal neurons. |
2012-02-21 |
2023-08-12 |
Not clear |
| Elisabetta Perdona', Vivian J A Costantini, Michela Tessari, Prisca Martinelli, Corrado Carignani, Enzo Valerio, M H Selina Mok, Laura Zonzini, Filippo Visentini, Massimo Gianotti, Laurie Gordon, Magalie Rocheville, Mauro Corsi, Anna Maria Capell. In vitro and in vivo characterization of the novel GABAB receptor positive allosteric modulator, 2-{1-[2-(4-chlorophenyl)-5-methylpyrazolo[1,5-a]pyrimidin-7-yl]-2-piperidinyl}ethanol (CMPPE). Neuropharmacology. vol 61. issue 5-6. 2012-02-16. PMID:21756923. |
a similar modulatory effect was observed in gaba(b) receptor-mediated activation of inwardly rectifying potassium channels in hippocampal neurons. |
2012-02-16 |
2023-08-12 |
human |
| Benjamin R Rost, Patrick Nicholson, Gudrun Ahnert-Hilger, Andreas Rummel, Christian Rosenmund, Joerg Breustedt, Dietmar Schmit. Activation of metabotropic GABA receptors increases the energy barrier for vesicle fusion. Journal of cell science. vol 124. issue Pt 18. 2012-02-13. PMID:21852427. |
we report here that in addition to the regulation of ca(2+) channel activity, metabotropic gaba(b) receptors (gaba(b)rs) at murine hippocampal glutamatergic synapses utilize an inhibitory pathway that directly targets the synaptic vesicle release machinery. |
2012-02-13 |
2023-08-12 |
Not clear |
| Matthew D Rannals, Jaideep Kapu. Homeostatic strengthening of inhibitory synapses is mediated by the accumulation of GABA(A) receptors. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 48. 2012-02-09. PMID:22131430. |
the amplitude and frequency of mipscs in hippocampal neurons increased after 48 h of ha, and increases in the size of gaba(a) receptor γ2 subunit clusters and presynaptic gad-65 puncta were observed. |
2012-02-09 |
2023-08-12 |
Not clear |
| Maryam Farahmandfar, Mohammad-Reza Zarrindast, Mehdi Kadivar, Seyed Morteza Karimian, Nasser Naghd. The effect of morphine sensitization on extracellular concentrations of GABA in dorsal hippocampus of male rats. European journal of pharmacology. vol 669. issue 1-3. 2012-02-08. PMID:21872582. |
the effect of morphine sensitization on extracellular concentrations of gaba in dorsal hippocampus of male rats. |
2012-02-08 |
2023-08-12 |
rat |