| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xuanmao Chen, Paul Whissell, Beverley A Orser, John F MacDonal. Functional modifications of acid-sensing ion channels by ligand-gated chloride channels. PloS one. vol 6. issue 7. 2011-11-22. PMID:21789198. |
here we show that asics were reversibly inhibited by activation of gaba(a) receptors in murine hippocampal neurons. |
2011-11-22 |
2023-08-12 |
Not clear |
| Xuanmao Chen, Paul Whissell, Beverley A Orser, John F MacDonal. Functional modifications of acid-sensing ion channels by ligand-gated chloride channels. PloS one. vol 6. issue 7. 2011-11-22. PMID:21789198. |
modification of asics by open gaba(a) receptors was also observed in both nucleated patches and outside-out patches excised from hippocampal neurons. |
2011-11-22 |
2023-08-12 |
Not clear |
| Xuanmao Chen, Paul Whissell, Beverley A Orser, John F MacDonal. Functional modifications of acid-sensing ion channels by ligand-gated chloride channels. PloS one. vol 6. issue 7. 2011-11-22. PMID:21789198. |
interestingly, asics and gaba(a) receptors interacted to regulate synaptic plasticity in ca1 hippocampal slices. |
2011-11-22 |
2023-08-12 |
Not clear |
| Vasco C Sousa, Natália Assaife-Lopes, Joaquim A Ribeiro, Judith A Pratt, Ros R Brett, Ana M Sebastiã. Regulation of hippocampal cannabinoid CB1 receptor actions by adenosine A1 receptors and chronic caffeine administration: implications for the effects of Δ9-tetrahydrocannabinol on spatial memory. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 36. issue 2. 2011-11-14. PMID:20927050. |
although adenosine a(1) receptors have a central role in fine-tuning excitatory transmission in the hippocampus, a(1) receptors localized in gabaergic cells do not directly influence gaba release. |
2011-11-14 |
2023-08-12 |
mouse |
| Vasco C Sousa, Natália Assaife-Lopes, Joaquim A Ribeiro, Judith A Pratt, Ros R Brett, Ana M Sebastiã. Regulation of hippocampal cannabinoid CB1 receptor actions by adenosine A1 receptors and chronic caffeine administration: implications for the effects of Δ9-tetrahydrocannabinol on spatial memory. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 36. issue 2. 2011-11-14. PMID:20927050. |
we first tested the hypothesis that an a(1)-cb(1) interaction influences gaba and glutamate release in the hippocampus. |
2011-11-14 |
2023-08-12 |
mouse |
| Vasco C Sousa, Natália Assaife-Lopes, Joaquim A Ribeiro, Judith A Pratt, Ros R Brett, Ana M Sebastiã. Regulation of hippocampal cannabinoid CB1 receptor actions by adenosine A1 receptors and chronic caffeine administration: implications for the effects of Δ9-tetrahydrocannabinol on spatial memory. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 36. issue 2. 2011-11-14. PMID:20927050. |
this study shows that a(1) receptors exert a negative modulatory effect on cb(1)-mediated inhibition of gaba and glutamate release, and provides the first evidence of chronic caffeine-induced alterations on the cannabinoid system in the cortex and hippocampus, with functional implications in spatial memory. |
2011-11-14 |
2023-08-12 |
mouse |
| Rosemarie Grantyn, Christian Henneberger, René Jüttner, Jochen C Meier, Sergei Kirischu. Functional hallmarks of GABAergic synapse maturation and the diverse roles of neurotrophins. Frontiers in cellular neuroscience. vol 5. 2011-11-10. PMID:21772813. |
here we focus on the performance of gabaergic synapses in two brain structures, the hippocampus and the superior colliculus, describe some novel aspects of neurotrophin effects during the development of gabaergic synaptic transmission and examine the applicability of the following rules: (1) synaptic transmission starts with gaba, (2) nascent/immature gabaergic synapses operate in a ballistic mode (multivesicular release), (3) immature synaptic terminals release vesicles with higher probability than mature synapses, (4) immature gabaergic synapses are prone to paired pulse and tetanic depression, (5) synapse maturation is characterized by an increasing dominance of synchronous over asynchronous release, (6) in immature neurons gaba acts as a depolarizing transmitter, (7) synapse maturation implies inhibitory postsynaptic current shortening due to an increase in alpha1 subunit expression, (8) extrasynaptic (tonic) conductances can inhibit the development of synaptic (phasic) gaba actions. |
2011-11-10 |
2023-08-12 |
Not clear |
| Xiao-Tao Jin, Adriana Galvan, Thomas Wichmann, Yoland Smit. Localization and Function of GABA Transporters GAT-1 and GAT-3 in the Basal Ganglia. Frontiers in systems neuroscience. vol 5. 2011-11-10. PMID:21847373. |
these transporters are widely expressed in neuronal (mainly gat-1) and glial (mainly gat-3) elements throughout the brain, but most data obtained so far relate to their role in the regulation of gaba(a) receptor-mediated postsynaptic tonic and phasic inhibition in the hippocampus, cerebral cortex and cerebellum. |
2011-11-10 |
2023-08-12 |
Not clear |
| Asha Suryanarayanan, Jing Liang, Edward M Meyer, A Kerstin Lindemeyer, Dev Chandra, Gregg E Homanics, Werner Sieghart, Richard W Olsen, Igor Spigelma. Subunit Compensation and Plasticity of Synaptic GABA(A) Receptors Induced by Ethanol in α4 Subunit Knockout Mice. Frontiers in neuroscience. vol 5. 2011-11-10. PMID:21977012. |
the hippocampus of naive ko mice showed reduced δ subunit protein levels, but increased α2, and γ2 levels compared to wild-type (wt) controls, suggesting at least partial compensation by these subunits in synaptic, highly etoh-sensitive gaba(a)rs of ko mice. |
2011-11-10 |
2023-08-12 |
mouse |
| Hae Young Lee, Byoung-Chul Yang, Eun-Shil Lee, Jong Ii Chung, Phil Ok Koh, Moon Seok Park, Myeong Ok Ki. Modulation by the GABA(B) receptor siRNA of ethanol-mediated PKA-α, CaMKII, and p-CREB intracellular signaling in prenatal rat hippocampal neurons. Anatomy & cell biology. vol 44. issue 3. 2011-11-10. PMID:22025973. |
modulation by the gaba(b) receptor sirna of ethanol-mediated pka-α, camkii, and p-creb intracellular signaling in prenatal rat hippocampal neurons. |
2011-11-10 |
2023-08-12 |
rat |
| Hae Young Lee, Byoung-Chul Yang, Eun-Shil Lee, Jong Ii Chung, Phil Ok Koh, Moon Seok Park, Myeong Ok Ki. Modulation by the GABA(B) receptor siRNA of ethanol-mediated PKA-α, CaMKII, and p-CREB intracellular signaling in prenatal rat hippocampal neurons. Anatomy & cell biology. vol 44. issue 3. 2011-11-10. PMID:22025973. |
et increased gaba(b1)r protein levels, but decreased protein kinase a-α (pka-α), calcium/calmodulin-dependent protein kinase ii (camkii) and phosphorylation of camp-response element binding protein (p-creb), in cultured hippocampal neurons harvested at gestation day 17.5. |
2011-11-10 |
2023-08-12 |
rat |
| Ilgam Khalilov, Geneviève Chazal, Ilona Chudotvorova, Christophe Pellegrino, Séverine Corby, Nadine Ferrand, Olena Gubkina, Romain Nardou, Roman Tyzio, Sumii Yamamoto, Thomas J Jentsch, Christian A Hübner, Jean-Luc Gaiarsa, Yehezkel Ben-Ari, Igor Medin. Enhanced Synaptic Activity and Epileptiform Events in the Embryonic KCC2 Deficient Hippocampus. Frontiers in cellular neuroscience. vol 5. 2011-11-10. PMID:22065950. |
the neuronal potassium-chloride co-transporter 2 [indicated thereafter as kcc2 (for protein) and kcc2 (for gene)] is thought to play an important role in the post natal excitatory to inhibitory switch of gaba actions in the rodent hippocampus. |
2011-11-10 |
2023-08-12 |
mouse |
| H C Lasseter, X Xie, D R Ramirez, R A Fuch. Sub-region specific contribution of the ventral hippocampus to drug context-induced reinstatement of cocaine-seeking behavior in rats. Neuroscience. vol 171. issue 3. 2011-10-31. PMID:20870011. |
rats received bilateral microinfusions of the gaba agonist cocktail, baclofen+muscimol (bm: 1.0/.01 mm), or vehicle into the vhp, dg, or the posterior dorsal hippocampus (pdh; extra-vh control) immediately before each test session. |
2011-10-31 |
2023-08-12 |
rat |
| A Tarasenko, O Krupko, N Himmelreic. Presynaptic kainate and NMDA receptors are implicated in the modulation of GABA release from cortical and hippocampal nerve terminals. Neurochemistry international. vol 59. issue 1. 2011-10-27. PMID:21672579. |
presynaptic kainate and nmda receptors are implicated in the modulation of gaba release from cortical and hippocampal nerve terminals. |
2011-10-27 |
2023-08-12 |
rat |
| Yi-Yi Wang, Shi-Chang Liu, Zhuo Yang, Tao Zhan. Impaired hippocampal synaptic plasticity in C6 glioma-bearing rats. Journal of neuro-oncology. vol 103. issue 3. 2011-10-25. PMID:21063897. |
the glutamate and γ-aminobutyric acid (gaba) content of contralateral hippocampus were quantified by high-performance liquid chromatography (hplc). |
2011-10-25 |
2023-08-12 |
rat |
| Michel Aimé Picardo, Philippe Guigue, Paolo Bonifazi, Renata Batista-Brito, Camille Allene, Alain Ribas, Gord Fishell, Agnès Baude, Rosa Cossar. Pioneer GABA cells comprise a subpopulation of hub neurons in the developing hippocampus. Neuron. vol 71. issue 4. 2011-10-25. PMID:21867885. |
pioneer gaba cells comprise a subpopulation of hub neurons in the developing hippocampus. |
2011-10-25 |
2023-08-12 |
Not clear |
| Tal Laviv, Irena Vertkin, Yevgeny Berdichevsky, Hilla Fogel, Inbal Riven, Bernhard Bettler, Paul A Slesinger, Inna Slutsk. Compartmentalization of the GABAB receptor signaling complex is required for presynaptic inhibition at hippocampal synapses. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 35. 2011-10-21. PMID:21880914. |
using fret spectroscopy, we provide evidence for formation of spatially restricted (<100 Å) complexes between gaba(b) receptors composed of gb(1a)/gb(2) subunits, gα(o)β(1)γ(2) g-protein heterotrimer, and ca(v)2.2 channels in hippocampal boutons. |
2011-10-21 |
2023-08-12 |
Not clear |
| Tal Laviv, Irena Vertkin, Yevgeny Berdichevsky, Hilla Fogel, Inbal Riven, Bernhard Bettler, Paul A Slesinger, Inna Slutsk. Compartmentalization of the GABAB receptor signaling complex is required for presynaptic inhibition at hippocampal synapses. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 35. 2011-10-21. PMID:21880914. |
thus, compartmentalization of the gaba(b1a) receptor, gβγ, and ca(v)2.2 channel in a signaling complex is required for presynaptic inhibition at hippocampal synapses. |
2011-10-21 |
2023-08-12 |
Not clear |
| Ivan Pavlov, Annalisa Scimemi, Leonid Savtchenko, Dimitri M Kullmann, Matthew C Walke. I(h)-mediated depolarization enhances the temporal precision of neuronal integration. Nature communications. vol 2. 2011-10-18. PMID:21326231. |
these results indicate that the hyperpolarizing component of gaba(a) receptor-mediated inhibition has an important role in maintaining the temporal fidelity of coincidence detection and suggest a previously unrecognized mechanism by which i(h) modulates information processing in the hippocampus. |
2011-10-18 |
2023-08-12 |
Not clear |
| Elena A Kharlamov, Eka Lepsveridze, Maia Meparishvili, Revaz O Solomonia, Bo Lu, Eric R Miller, Kevin M Kelly, Zakaria Mtchedlishvil. Alterations of GABA(A) and glutamate receptor subunits and heat shock protein in rat hippocampus following traumatic brain injury and in posttraumatic epilepsy. Epilepsy research. vol 95. issue 1-2. 2011-10-18. PMID:21439793. |
alterations of gaba(a) and glutamate receptor subunits and heat shock protein in rat hippocampus following traumatic brain injury and in posttraumatic epilepsy. |
2011-10-18 |
2023-08-12 |
rat |