| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Elena A Kharlamov, Eka Lepsveridze, Maia Meparishvili, Revaz O Solomonia, Bo Lu, Eric R Miller, Kevin M Kelly, Zakaria Mtchedlishvil. Alterations of GABA(A) and glutamate receptor subunits and heat shock protein in rat hippocampus following traumatic brain injury and in posttraumatic epilepsy. Epilepsy research. vol 95. issue 1-2. 2011-10-18. PMID:21439793. |
recently, we reported differential alterations in tonic and phasic gaba(a) receptor (gaba(a)r) currents in hippocampal dentate granule cells 90 days after controlled cortical impact (cci) (mtchedlishvili et al., 2010). |
2011-10-18 |
2023-08-12 |
rat |
| Elena A Kharlamov, Eka Lepsveridze, Maia Meparishvili, Revaz O Solomonia, Bo Lu, Eric R Miller, Kevin M Kelly, Zakaria Mtchedlishvil. Alterations of GABA(A) and glutamate receptor subunits and heat shock protein in rat hippocampus following traumatic brain injury and in posttraumatic epilepsy. Epilepsy research. vol 95. issue 1-2. 2011-10-18. PMID:21439793. |
in the present study, we investigated long-term changes in the protein expression of gaba(a)r α1, α4, γ2, and δ subunits, nmda (nr2b) and ampa (glur1) receptor subunits, and heat shock proteins (hsp70 and hsp90) in the hippocampus of sprague-dawley rats evaluated by western blotting in controls, cci-injured animals without pte (cci group), and cci-injured animals with pte (pte group). |
2011-10-18 |
2023-08-12 |
rat |
| Inseon Song, Leonid Savtchenko, Alexey Semyano. Tonic excitation or inhibition is set by GABA(A) conductance in hippocampal interneurons. Nature communications. vol 2. 2011-10-18. PMID:21730957. |
tonic excitation or inhibition is set by gaba(a) conductance in hippocampal interneurons. |
2011-10-18 |
2023-08-12 |
Not clear |
| Inseon Song, Leonid Savtchenko, Alexey Semyano. Tonic excitation or inhibition is set by GABA(A) conductance in hippocampal interneurons. Nature communications. vol 2. 2011-10-18. PMID:21730957. |
here we show that ambient gaba, the main inhibitory neurotransmitter in the brain, can excite adult hippocampal interneurons. |
2011-10-18 |
2023-08-12 |
Not clear |
| A V Berezhnov, A V Kononov, E I Fedotova, V P Zinchenk. [A method for the detection and characterization of GABA(A) receptors by calcium-sensitive fluorescent probes]. Biofizika. vol 56. issue 4. 2011-10-18. PMID:21950070. |
the object of investigation was a young (two- to four-day-old) rat hippocampal cell culture in which gaba induces the depolarization and a transient increase in ca2+ concentration in the cytosol of neurons due to the activation of potential-dependent calcium channels. |
2011-10-18 |
2023-08-12 |
rat |
| Enrico Cherubini, Marilena Griguoli, Victoria Safiulina, Laura Lagosten. The depolarizing action of GABA controls early network activity in the developing hippocampus. Molecular neurobiology. vol 43. issue 2. 2011-10-14. PMID:21042953. |
the depolarizing action of gaba controls early network activity in the developing hippocampus. |
2011-10-14 |
2023-08-12 |
mouse |
| Enrico Cherubini, Marilena Griguoli, Victoria Safiulina, Laura Lagosten. The depolarizing action of GABA controls early network activity in the developing hippocampus. Molecular neurobiology. vol 43. issue 2. 2011-10-14. PMID:21042953. |
evidence has been recently provided that in chronically nerve growth factor-deprived mice expressing a progressive age-dependent neurodegenerative pathology resembling that observed in patients with alzheimer's disease, the reduced expression of mrna encoding for the kcc2 gene and the depolarizing action of gaba lead to the reorganization of the neuronal hippocampal network. |
2011-10-14 |
2023-08-12 |
mouse |
| Jiu-Gang Xue, Takayoshi Masuoka, Xian-Di Gong, Ken-Shiung Chen, Yuchio Yanagawa, S K Alex Law, Shiro Konish. NMDA receptor activation enhances inhibitory GABAergic transmission onto hippocampal pyramidal neurons via presynaptic and postsynaptic mechanisms. Journal of neurophysiology. vol 105. issue 6. 2011-10-14. PMID:21471392. |
here, we report that a brief application of nmda could induce two distinct actions in ca1 pyramidal neurons in mouse hippocampal slices: 1) an inward current attributed to activation of postsynaptic nmdars; and 2) fast phasic synaptic currents, namely spontaneous inhibitory postsynaptic currents (sipscs), mediated by gaba(a) receptors in pyramidal neurons. |
2011-10-14 |
2023-08-12 |
mouse |
| Gaetan Lesca, Marianne Till, Audrey Labalme, Dominique Vallee, Catherine Hugonenq, Nicole Philip, Patrick Edery, Damien Sanlavill. De novo Xq11.11 microdeletion including ARHGEF9 in a boy with mental retardation, epilepsy, macrosomia, and dysmorphic features. American journal of medical genetics. Part A. vol 155A. issue 7. 2011-10-14. PMID:21626670. |
cb-deficient male mice show reduced exploratory behavior, impaired spatial learning, increased anxiety scores, and reduction of gephyrin-dependent gaba receptor clusters in amygdala and hippocampus. |
2011-10-14 |
2023-08-12 |
mouse |
| Somrudee Saiyudthong, Charles A Marsde. Acute effects of bergamot oil on anxiety-related behaviour and corticosterone level in rats. Phytotherapy research : PTR. vol 25. issue 6. 2011-10-12. PMID:21105176. |
a previous study showed that beo significantly increased gamma-aminobutyric acid levels in rat hippocampus, suggesting potential anxiolytic properties. |
2011-10-12 |
2023-08-12 |
rat |
| T van der Vaart, G M van Woerden, Y Elgersma, C I de Zeeuw, M Schonewill. Motor deficits in neurofibromatosis type 1 mice: the role of the cerebellum. Genes, brain, and behavior. vol 10. issue 4. 2011-10-07. PMID:21352477. |
although cognitive deficits in nf1 have been attributed to increased release of the inhibitory neurotransmitter γ-amino butyric acid (gaba) in the hippocampus, the origin of the motor deficits is unknown. |
2011-10-07 |
2023-08-12 |
mouse |
| Shane A Perrine, Farhad Ghoddoussi, Mark S Michaels, Elisabeth M Hyde, Donald M Kuhn, Matthew P Gallowa. MDMA administration decreases serotonin but not N-acetylaspartate in the rat brain. Neurotoxicology. vol 31. issue 6. 2011-09-29. PMID:20800616. |
glutamate levels were increased in prefrontal cortex and decreased in hippocampus, while gaba levels were decreased only in hippocampus. |
2011-09-29 |
2023-08-12 |
human |
| Shane A Perrine, Farhad Ghoddoussi, Mark S Michaels, Elisabeth M Hyde, Donald M Kuhn, Matthew P Gallowa. MDMA administration decreases serotonin but not N-acetylaspartate in the rat brain. Neurotoxicology. vol 31. issue 6. 2011-09-29. PMID:20800616. |
however, the collective pattern of changes in 5ht, ins, glutamate and gaba is consistent with persistent hippocampal neuroadaptations caused by mdma. |
2011-09-29 |
2023-08-12 |
human |
| Anna Di Vito, Giuseppina Giusi, Raffaella Alò, Antonella Piscioneri, Sabrina Morelli, Loredana De Bartolo, Marcello Canonac. Distinct α GABA(A)R subunits influence structural and transcriptional properties of CA1 hippocampal neurons. Neuroscience letters. vol 496. issue 2. 2011-09-29. PMID:21511007. |
distinct α gaba(a)r subunits influence structural and transcriptional properties of ca1 hippocampal neurons. |
2011-09-29 |
2023-08-12 |
Not clear |
| Mark R Etherton, Katsuhiko Tabuchi, Manu Sharma, Jaewon Ko, Thomas C Südho. An autism-associated point mutation in the neuroligin cytoplasmic tail selectively impairs AMPA receptor-mediated synaptic transmission in hippocampus. The EMBO journal. vol 30. issue 14. 2011-09-29. PMID:21642956. |
specifically, the r704c mutation caused a major and selective decrease in ampa receptor-mediated synaptic transmission in pyramidal neurons of the hippocampus, without similarly changing nmda or gaba receptor-mediated synaptic transmission, and without detectably altering presynaptic neurotransmitter release. |
2011-09-29 |
2023-08-12 |
mouse |
| Mai Marie Holm, Jose Luis Nieto-Gonzalez, Irina Vardya, Kim Henningsen, Magdalena Niepsuj Jayatissa, Ove Wiborg, Kimmo Jense. Hippocampal GABAergic dysfunction in a rat chronic mild stress model of depression. Hippocampus. vol 21. issue 4. 2011-09-28. PMID:20087886. |
in hippocampal brain slices, phasic, and tonic gaba(a) receptor-mediated currents in dentate gyrus granule cells were examined using patch-clamp recordings. |
2011-09-28 |
2023-08-12 |
rat |
| Mai Marie Holm, Jose Luis Nieto-Gonzalez, Irina Vardya, Kim Henningsen, Magdalena Niepsuj Jayatissa, Ove Wiborg, Kimmo Jense. Hippocampal GABAergic dysfunction in a rat chronic mild stress model of depression. Hippocampus. vol 21. issue 4. 2011-09-28. PMID:20087886. |
in summary, we have revealed a hippocampal dysfunction in the gabaergic system in the chronic mild stress model of depression in rats, caused by a reduction in action potential-dependent gaba release. |
2011-09-28 |
2023-08-12 |
rat |
| Sung Ung Kang, Seok Heo, Gert Lube. Mass spectrometric analysis of GABAA receptor subtypes and phosphorylations from mouse hippocampus. Proteomics. vol 11. issue 11. 2011-09-27. PMID:21538884. |
the method used herein enables identification of several gaba(a) r subunits from mouse hippocampus along with phosphorylations of β-1 (t227, y230), β-2 (y215, t439) and β-3 (t282, s406) subunits. |
2011-09-27 |
2023-08-12 |
mouse |
| Nicola Kuczewski, Celine Fuchs, Nadine Ferrand, Jasmina N Jovanovic, Jean-Luc Gaiarsa, Christophe Porche. Mechanism of GABAB receptor-induced BDNF secretion and promotion of GABAA receptor membrane expression. Journal of neurochemistry. vol 118. issue 4. 2011-09-16. PMID:21255015. |
in a previous study, we reported that gaba(b) receptor activation triggers secretion of brain-derived neurotrophic factor (bdnf) and promotes the functional maturation of gabaergic synapses in the developing rat hippocampus. |
2011-09-16 |
2023-08-12 |
rat |
| Z Vadachkoria, L Dzidziguri, E Bakuradze, G Mosidze, I Modebadze, D Dzidzigur. Influence of halothane narcosis on a change of the number of GABA-positive cells in the hippocampus of adult rats with the midasolam premedication. Georgian medical news. issue 193. 2011-09-16. PMID:21617274. |
the purpose of present study is to investigate a change of the quantity of gaba positive cells in the hippocampus of white adult rats under the conditions of halothane narcosis and with the premedication by midazolam. |
2011-09-16 |
2023-08-12 |
human |