| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Woong Ki Choi, David Wirtshafter, Hyun-Jung Park, Mi-Sook Lee, Song Her, Insop Shi. The characteristics of supramammillary cells projecting to the hippocampus in stress response in the rat. The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology. vol 16. issue 1. 2012-10-02. PMID:22416215. |
by contrast, a few retrogradely labeled cells projecting to the hippocampus were immunoreactive for dopamine, γ-aminobutyric acid (gaba) and no. |
2012-10-02 |
2023-08-12 |
rat |
| Piotr Bregestovski, Christophe Bernar. Excitatory GABA: How a Correct Observation May Turn Out to be an Experimental Artifact. Frontiers in pharmacology. vol 3. 2012-10-02. PMID:22529813. |
however, in vivo measurements as well as observations made in intact hippocampal preparations indicate that gaba is in fact inhibitory in rodents at early neonatal stages. |
2012-10-02 |
2023-08-12 |
Not clear |
| Jia Qi, Wen-Yan Han, Jing-Yu Yang, Li-Hui Wang, Ying-Xu Dong, Fang Wang, Ming Song, Chun-Fu W. Oxytocin regulates changes of extracellular glutamate and GABA levels induced by methamphetamine in the mouse brain. Addiction biology. vol 17. issue 4. 2012-10-01. PMID:22507692. |
in the present study, we investigated the effects of ot on extracellular levels of glutamate (glu) and γ-aminobutyric acid (gaba) induced by methamphetamine (map) in the medial prefrontal cortex (mpfc) and dorsal hippocampus (dhc) of freely moving mice, using in vivo microdialysis coupled to high-performance liquid chromatography and fluorescence detection. |
2012-10-01 |
2023-08-12 |
mouse |
| B S Hemanth Kumar, Sushanta Kumar Mishra, Poonam Rana, Sadhana Singh, Subash Khush. Neurodegenerative evidences during early onset of depression in CMS rats as detected by proton magnetic resonance spectroscopy at 7 T. Behavioural brain research. vol 232. issue 1. 2012-09-27. PMID:22449862. |
the results revealed a significant decrease of glutamate (glu), glutamine (gln), naa+naag, glx and gaba levels in both hippocampus and prefrontal cortex of cms animals and an elevated level of myo-ionisitol (mi) and taurine (tau) was observed only in hippocampus. |
2012-09-27 |
2023-08-12 |
rat |
| Andrea J Hickey, James N Reynolds, Richard J Beninge. Post-weaning social isolation and subchronic NMDA glutamate receptor blockade: effects on locomotor activity and GABA signaling in the rat suggest independent mechanisms. Pharmacology, biochemistry, and behavior. vol 101. issue 2. 2012-09-24. PMID:22293110. |
at p70, all groups were tested for locomotor activity and subsequently sacrificed to assess gat-1 activity and gaba(a) receptor expression in the frontal cortex and hippocampus. |
2012-09-24 |
2023-08-12 |
rat |
| Andrea J Hickey, James N Reynolds, Richard J Beninge. Post-weaning social isolation and subchronic NMDA glutamate receptor blockade: effects on locomotor activity and GABA signaling in the rat suggest independent mechanisms. Pharmacology, biochemistry, and behavior. vol 101. issue 2. 2012-09-24. PMID:22293110. |
si resulted in increased locomotor activity, gat-1 activity in frontal cortex and hippocampus and gaba(a) receptor expression in the frontal cortex; mk-801 increased gaba(a) receptor expression in the hippocampus. |
2012-09-24 |
2023-08-12 |
rat |
| Andrea J Hickey, James N Reynolds, Richard J Beninge. Post-weaning social isolation and subchronic NMDA glutamate receptor blockade: effects on locomotor activity and GABA signaling in the rat suggest independent mechanisms. Pharmacology, biochemistry, and behavior. vol 101. issue 2. 2012-09-24. PMID:22293110. |
activity changes were correlated with changes in hippocampal gat-1 and frontocortical gaba(a) receptor number. |
2012-09-24 |
2023-08-12 |
rat |
| Doodipala Samba Reddy, Jordan Gould, O Gangisett. A mouse kindling model of perimenstrual catamenial epilepsy. The Journal of pharmacology and experimental therapeutics. vol 341. issue 3. 2012-09-24. PMID:22434675. |
the increased susceptibility to seizures and alterations in antiseizure drug responses are associated with increased abundance of the α4 and δ subunits of gaba(a) receptors in the hippocampus. |
2012-09-24 |
2023-08-12 |
mouse |
| Md N Islam, R Fujinaga, A Yanai, M R Jahan, Y Takeshita, K Kokubu, K Shinod. Characterization of the "sporadically lurking HAP1-immunoreactive (SLH) cells" in the hippocampus, with special reference to the expression of steroid receptors, GABA, and progenitor cell markers. Neuroscience. vol 210. 2012-09-21. PMID:22421101. |
characterization of the "sporadically lurking hap1-immunoreactive (slh) cells" in the hippocampus, with special reference to the expression of steroid receptors, gaba, and progenitor cell markers. |
2012-09-21 |
2023-08-12 |
rat |
| R A Saadi, K He, K A Hartnett, K Kandler, M Hershfinkel, E Aizenma. SNARE-dependent upregulation of potassium chloride co-transporter 2 activity after metabotropic zinc receptor activation in rat cortical neurons in vitro. Neuroscience. vol 210. 2012-09-21. PMID:22441041. |
in a recent study, we showed that zn(2+) regulates gaba(a) reversal potentials in the hippocampus by enhancing the activity of kcc2 through an increase in its surface expression. |
2012-09-21 |
2023-08-12 |
mouse |
| Ming Teng Ko. [Pharmacological treatment strategies targeting cognitive impairment associated with aging]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica. vol 139. issue 4. 2012-09-20. PMID:22498679. |
because excess hippocampal activation is also observed in amci, our findings support the use of antiepileptic or gaba(a) α5 agonist therapy in amci. |
2012-09-20 |
2023-08-12 |
rat |
| Alexander M Kleschevnikov, Pavel V Belichenko, Mehrdad Faizi, Lucia F Jacobs, Khin Htun, Mehrdad Shamloo, William C Moble. Deficits in cognition and synaptic plasticity in a mouse model of Down syndrome ameliorated by GABAB receptor antagonists. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 32. issue 27. 2012-09-18. PMID:22764230. |
in hippocampal slices, treatment with the gaba(b) receptor antagonists cgp55845 or cgp52432 enhanced long-term potentiation (ltp) in the ts65dn dg. |
2012-09-18 |
2023-08-12 |
mouse |
| Fumihiro Niwa, Hiroko Bannai, Misa Arizono, Kazumi Fukatsu, Antoine Triller, Katsuhiko Mikoshib. Gephyrin-independent GABA(A)R mobility and clustering during plasticity. PloS one. vol 7. issue 4. 2012-09-17. PMID:22563445. |
in cultured hippocampal neurons, quantitative immunocytochemistry showed that the dispersal of synaptic gaba(a)rs accompanied with neuronal excitation evoked by 4-aminopyridine (4ap) or n-methyl-d-aspartic acid (nmda) precedes that of gephyrin. |
2012-09-17 |
2023-08-12 |
Not clear |
| Thiago Vignoli, Astrid Nehlig, Silvia Gomes Massironi, Rita de Cássia Sinigaglia Coimbra, Maria da Graça Naffah Mazzacoratti, Iara Ribeiro Silva, Eduardo Ferreira de Castro Neto, Daniele Suzete Persike, Maria José da Silva Fernande. Consequences of pilocarpine-induced status epilepticus in immunodeficient mice. Brain research. vol 1450. 2012-09-14. PMID:22405727. |
a significant increase in the level of glutamate and gaba was found in the hippocampus and cortex of balb/c mice presenting se in comparison to controls. |
2012-09-14 |
2023-08-12 |
mouse |
| Guillaume Sandoz, Joshua Levitz, Richard H Kramer, Ehud Y Isacof. Optical control of endogenous proteins with a photoswitchable conditional subunit reveals a role for TREK1 in GABA(B) signaling. Neuron. vol 74. issue 6. 2012-09-14. PMID:22726831. |
we find that trek1, typically considered to be a leak channel, contributes to the hippocampal gaba(b) response. |
2012-09-14 |
2023-08-12 |
Not clear |
| Min-Lan Tsai, Melanie Crutchley, Richard Boyce, Jingyi Ma, Francis Boon, D Peter Cain, L Stan Leun. Long-lasting auditory gating deficit accompanied by GABA(B) receptor dysfunction in the hippocampus after early-life limbic seizures in rats. Physiology & behavior. vol 106. issue 4. 2012-09-04. PMID:22504497. |
long-lasting auditory gating deficit accompanied by gaba(b) receptor dysfunction in the hippocampus after early-life limbic seizures in rats. |
2012-09-04 |
2023-08-12 |
rat |
| Min-Lan Tsai, Melanie Crutchley, Richard Boyce, Jingyi Ma, Francis Boon, D Peter Cain, L Stan Leun. Long-lasting auditory gating deficit accompanied by GABA(B) receptor dysfunction in the hippocampus after early-life limbic seizures in rats. Physiology & behavior. vol 106. issue 4. 2012-09-04. PMID:22504497. |
in a previous study, we reported a rat model of early-life limbic seizures which resulted in a loss of gaba(b) receptor inhibition in the hippocampus. |
2012-09-04 |
2023-08-12 |
rat |
| Min-Lan Tsai, Melanie Crutchley, Richard Boyce, Jingyi Ma, Francis Boon, D Peter Cain, L Stan Leun. Long-lasting auditory gating deficit accompanied by GABA(B) receptor dysfunction in the hippocampus after early-life limbic seizures in rats. Physiology & behavior. vol 106. issue 4. 2012-09-04. PMID:22504497. |
since gating of auditory evoked potentials in the hippocampus (auditory gating) requires gaba(b) receptors and spatial behaviors depend on the hippocampus, we hypothesize that rats with early-life limbic seizures manifest deficits of auditory gating and spatial behaviors. |
2012-09-04 |
2023-08-12 |
rat |
| Min-Lan Tsai, Melanie Crutchley, Richard Boyce, Jingyi Ma, Francis Boon, D Peter Cain, L Stan Leun. Long-lasting auditory gating deficit accompanied by GABA(B) receptor dysfunction in the hippocampus after early-life limbic seizures in rats. Physiology & behavior. vol 106. issue 4. 2012-09-04. PMID:22504497. |
heterosynaptic electric paired-pulse depression of hippocampal population excitatory postsynaptic potential in freely moving rats, a measure of hippocampal gaba(b)-receptor mediated inhibition, was decreased in seizure as compared to control rats. |
2012-09-04 |
2023-08-12 |
rat |
| Min-Lan Tsai, Melanie Crutchley, Richard Boyce, Jingyi Ma, Francis Boon, D Peter Cain, L Stan Leun. Long-lasting auditory gating deficit accompanied by GABA(B) receptor dysfunction in the hippocampus after early-life limbic seizures in rats. Physiology & behavior. vol 106. issue 4. 2012-09-04. PMID:22504497. |
in conclusion, early-life limbic seizures induced a long-lasting deficit in auditory gating, likely caused by gaba(b) receptor-mediated inhibition loss in the hippocampus. |
2012-09-04 |
2023-08-12 |
rat |