| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Min-Lan Tsai, Melanie Crutchley, Richard Boyce, Jingyi Ma, Francis Boon, D Peter Cain, L Stan Leun. Long-lasting auditory gating deficit accompanied by GABA(B) receptor dysfunction in the hippocampus after early-life limbic seizures in rats. Physiology & behavior. vol 106. issue 4. 2012-09-04. PMID:22504497. |
auditory gating loss is a symptom of schizophrenia, and thus gaba(b) receptor inhibition loss in the hippocampus provides a mechanism linking early-life seizures to a psychiatric symptom. |
2012-09-04 |
2023-08-12 |
rat |
| C Geoffrey Lau, Venkatesh N Murth. Activity-dependent regulation of inhibition via GAD67. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 32. issue 25. 2012-08-30. PMID:22723692. |
homozygous deletion of gad1 significantly reduced miniature inhibitory postsynaptic current (mipsc) amplitudes and gaba levels in cultured hippocampal neurons. |
2012-08-30 |
2023-08-12 |
mouse |
| Karim Le Meur, Juan Mendizabal-Zubiaga, Pedro Grandes, Etienne Audina. GABA release by hippocampal astrocytes. Frontiers in computational neuroscience. vol 6. 2012-08-23. PMID:22912614. |
gaba release by hippocampal astrocytes. |
2012-08-23 |
2023-08-12 |
rat |
| Karim Le Meur, Juan Mendizabal-Zubiaga, Pedro Grandes, Etienne Audina. GABA release by hippocampal astrocytes. Frontiers in computational neuroscience. vol 6. 2012-08-23. PMID:22912614. |
here, we used whole-cell recordings in rat acute brain slices and electron microscopy to test whether hippocampal astrocytes release the inhibitory transmitter gaba. |
2012-08-23 |
2023-08-12 |
rat |
| Karim Le Meur, Juan Mendizabal-Zubiaga, Pedro Grandes, Etienne Audina. GABA release by hippocampal astrocytes. Frontiers in computational neuroscience. vol 6. 2012-08-23. PMID:22912614. |
we observed that slow transient inhibitory currents due to the activation of gaba(a) receptors occur spontaneously in principal neurons of the three main hippocampal fields (ca1, ca3, and dentate gyrus). |
2012-08-23 |
2023-08-12 |
rat |
| Karim Le Meur, Juan Mendizabal-Zubiaga, Pedro Grandes, Etienne Audina. GABA release by hippocampal astrocytes. Frontiers in computational neuroscience. vol 6. 2012-08-23. PMID:22912614. |
yet, electron microscopy examination of immunostained hippocampal sections shows that about 80% of hippocampal astrocytes [positive for glial fibrillary acidic protein (gfap)] were immunostained for gaba. |
2012-08-23 |
2023-08-12 |
rat |
| Karim Le Meur, Juan Mendizabal-Zubiaga, Pedro Grandes, Etienne Audina. GABA release by hippocampal astrocytes. Frontiers in computational neuroscience. vol 6. 2012-08-23. PMID:22912614. |
the relevance of the astrocytic release of gaba, and glutamate, on the physiopathology of the hippocampus remains to be established. |
2012-08-23 |
2023-08-12 |
rat |
| Ethel Antunes Wilhelm, Bibiana Mozzaquatro Gai, Ana Cristina Guerra Souza, Cristiani Folharini Bortolatto, Juliano Alex Roehrs, Cristina Wayne Nogueir. Involvement of GABAergic and glutamatergic systems in the anticonvulsant activity of 3-alkynyl selenophene in 21 day-old rats. Molecular and cellular biochemistry. vol 365. issue 1-2. 2012-08-20. PMID:22350757. |
), and [(3)h]γ-aminobutyric acid (gaba) and [(3)h]glutamate uptakes were carried out in slices of cerebral cortex and hippocampus. |
2012-08-20 |
2023-08-12 |
rat |
| Ethel Antunes Wilhelm, Bibiana Mozzaquatro Gai, Ana Cristina Guerra Souza, Cristiani Folharini Bortolatto, Juliano Alex Roehrs, Cristina Wayne Nogueir. Involvement of GABAergic and glutamatergic systems in the anticonvulsant activity of 3-alkynyl selenophene in 21 day-old rats. Molecular and cellular biochemistry. vol 365. issue 1-2. 2012-08-20. PMID:22350757. |
[(3)h]gaba uptake was decreased in cerebral cortex (64%) and hippocampus (58%) slices of 21 day-old rats treated with 3-asp. |
2012-08-20 |
2023-08-12 |
rat |
| Zhengtao Hu, Yi Deng, Chunyan Hu, Pengchi Deng, Qian Bu, Guangyan Yan, Jiaqing Zhou, Xue Shao, Jinxuan Zhao, Yan Li, Ruiming Zhu, Youzhi Xu, Yinglan Zhao, Xiaobo Ce. ¹H NMR-based metabonomic analysis of brain in rats of morphine dependence and withdrawal intervention. Behavioural brain research. vol 231. issue 1. 2012-08-20. PMID:22391120. |
we found that the concentrations of neurotransmitters including glutamate, glutamine and gamma-aminobutyric acid changed differentially in hippocampus, nac, pfc and striatum after repeated morphine treatment. |
2012-08-20 |
2023-08-12 |
rat |
| Joaquin N Lugo, Amy L Brewster, Corinne M Spencer, Anne E Anderso. Kv4.2 knockout mice have hippocampal-dependent learning and memory deficits. Learning & memory (Cold Spring Harbor, N.Y.). vol 19. issue 5. 2012-08-14. PMID:22505720. |
furthermore, total protein levels of the α5 or δ gaba(a)r subunits, which contribute to tonic inhibition, were unchanged in hippocampus. |
2012-08-14 |
2023-08-12 |
mouse |
| Sivan Subburaju, Francine M Bene. Induction of the GABA cell phenotype: an in vitro model for studying neurodevelopmental disorders. PloS one. vol 7. issue 3. 2012-08-03. PMID:22457755. |
recent studies of the hippocampus have suggested that a network of genes is associated with the regulation of the gad₆₇ (gad1) expression and may play a role in γ-amino butyric acid (gaba) dysfunction in schizophrenia (sz) and bipolar disorder (bd). |
2012-08-03 |
2023-08-12 |
Not clear |
| Sivan Subburaju, Francine M Bene. Induction of the GABA cell phenotype: an in vitro model for studying neurodevelopmental disorders. PloS one. vol 7. issue 3. 2012-08-03. PMID:22457755. |
to obtain a more detailed understanding of how gad₆₇ regulation may result in gabaergic dysfunction, we have developed an in vitro model in which gaba cells are differentiated from the hippocampal precursor cell line, hib5. |
2012-08-03 |
2023-08-12 |
Not clear |
| Sivan Subburaju, Francine M Bene. Induction of the GABA cell phenotype: an in vitro model for studying neurodevelopmental disorders. PloS one. vol 7. issue 3. 2012-08-03. PMID:22457755. |
overall, these results suggest that the hib5 cells can differentiate into functionally mature gaba neurons in the presence of gene products that are associated with gad₆₇ regulation in the adult hippocampus. |
2012-08-03 |
2023-08-12 |
Not clear |
| Logan T Knox, Yu Jing, Michael S Fleete, Nicola D Collie, Hu Zhang, Ping Li. Scopolamine impairs behavioural function and arginine metabolism in the rat dentate gyrus. Neuropharmacology. vol 61. issue 8. 2012-08-01. PMID:21903106. |
after completion of the behavioural testing, the ca1, ca2/3 and dentate gyrus (dg) sub-regions of the hippocampus and the prefrontal cortex were harvested to measure the activity and protein expression of nitric oxide synthase (nos) and arginase, and the levels of l-arginine, l-citrulline, l-ornithine, agmatine, putrescine, spermidine, spermine, glutamate and gaba. |
2012-08-01 |
2023-08-12 |
rat |
| Cristiano Bombard. Neuronal localization of 5-HT2A receptor immunoreactivity in the rat hippocampal region. Brain research bulletin. vol 87. issue 2-3. 2012-08-01. PMID:22119732. |
in the hippocampal formation (dentate gyrus, hippocampus proper and subiculum) and entorhinal cortex, the colocalization of the 5-ht2ar with the inhibitory transmitter γ-aminobutyric acid (gaba) was studied using double immunofluorescence confocal microscopy. |
2012-08-01 |
2023-08-12 |
rat |
| M G Dashniani, M A Burdzhanadze, T L Naneĭshvili, L B Kruashvili, M M Sephashvil. Effects of chronic memantine treatment on hippocampal extracellular glutamate and GABA levels during spatial alternation testing. Georgian medical news. issue 202. 2012-08-01. PMID:22392787. |
effects of chronic memantine treatment on hippocampal extracellular glutamate and gaba levels during spatial alternation testing. |
2012-08-01 |
2023-08-12 |
rat |
| M G Dashniani, M A Burdzhanadze, T L Naneĭshvili, L B Kruashvili, M M Sephashvil. Effects of chronic memantine treatment on hippocampal extracellular glutamate and GABA levels during spatial alternation testing. Georgian medical news. issue 202. 2012-08-01. PMID:22392787. |
these experiments examined the release of glutamate (glu) and gaba in the hippocampus of memantine (2,5mg/kg, i.p. |
2012-08-01 |
2023-08-12 |
rat |
| M G Dashniani, M A Burdzhanadze, T L Naneĭshvili, L B Kruashvili, M M Sephashvil. Effects of chronic memantine treatment on hippocampal extracellular glutamate and GABA levels during spatial alternation testing. Georgian medical news. issue 202. 2012-08-01. PMID:22392787. |
we found increase in kcl-stimulated glutamate and gaba release in the hippocampus of memantine treated rat compared to the saline treated rat. |
2012-08-01 |
2023-08-12 |
rat |
| M Rushaidhi, Y Jing, J T Kennard, N D Collie, J M Williams, H Zhang, P Li. Aging affects L-arginine and its metabolites in memory-associated brain structures at the tissue and synaptoneurosome levels. Neuroscience. vol 209. 2012-07-30. PMID:22387109. |
there were significant differences in l-arginine, l-citrulline, l-ornithine, agmatine, putrescine, spermidine, spermine, and glutamate, but not gaba, in the ca1, ca2/3, and dentate gyrus sub-regions of the hippocampus and the prefrontal, entorhinal, perirhinal, and postrhinal cortices in 24 (aged) and 4 (young) months old rats in a region-specific manner. |
2012-07-30 |
2023-08-12 |
rat |