| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Cai Zhang, Allan V Kalueff, Cai Son. Minocycline ameliorates anxiety-related self-grooming behaviors and alters hippocampal neuroinflammation, GABA and serum cholesterol levels in female Sprague-Dawley rats subjected to chronic unpredictable mild stress. Behavioural brain research. vol 363. 2019-08-26. PMID:30703398. |
minocycline ameliorates anxiety-related self-grooming behaviors and alters hippocampal neuroinflammation, gaba and serum cholesterol levels in female sprague-dawley rats subjected to chronic unpredictable mild stress. |
2019-08-26 |
2023-08-13 |
rat |
| Cai Zhang, Allan V Kalueff, Cai Son. Minocycline ameliorates anxiety-related self-grooming behaviors and alters hippocampal neuroinflammation, GABA and serum cholesterol levels in female Sprague-Dawley rats subjected to chronic unpredictable mild stress. Behavioural brain research. vol 363. 2019-08-26. PMID:30703398. |
(2019) study, to examine whether cums affects grooming behavior, and whether minocycline, a microglia antagonist, can correct these behavioral deficits, accompanied by altering hippocampal neuroinflammation, gaba and serum cholesterol levels. |
2019-08-26 |
2023-08-13 |
rat |
| Cai Zhang, Allan V Kalueff, Cai Son. Minocycline ameliorates anxiety-related self-grooming behaviors and alters hippocampal neuroinflammation, GABA and serum cholesterol levels in female Sprague-Dawley rats subjected to chronic unpredictable mild stress. Behavioural brain research. vol 363. 2019-08-26. PMID:30703398. |
serum cholesterol, inflammatory cytokines and gaba levels in hippocampus were assayed by elisa. |
2019-08-26 |
2023-08-13 |
rat |
| Cai Zhang, Allan V Kalueff, Cai Son. Minocycline ameliorates anxiety-related self-grooming behaviors and alters hippocampal neuroinflammation, GABA and serum cholesterol levels in female Sprague-Dawley rats subjected to chronic unpredictable mild stress. Behavioural brain research. vol 363. 2019-08-26. PMID:30703398. |
cums also lowered hippocampal gaba, whereas minocycline normalized cums-induced gaba in the hippocampus. |
2019-08-26 |
2023-08-13 |
rat |
| Cai Zhang, Allan V Kalueff, Cai Son. Minocycline ameliorates anxiety-related self-grooming behaviors and alters hippocampal neuroinflammation, GABA and serum cholesterol levels in female Sprague-Dawley rats subjected to chronic unpredictable mild stress. Behavioural brain research. vol 363. 2019-08-26. PMID:30703398. |
in summary, minocycline ameliorated cums-induced aberrant self-grooming behaviors in rats by altering hippocampal neuroinflammation, gaba and serum cholesterol levels. |
2019-08-26 |
2023-08-13 |
rat |
| Karri Lamsa, Petrina La. Long-term plasticity of hippocampal interneurons during in vivo memory processes. Current opinion in neurobiology. vol 54. 2019-08-22. PMID:30195105. |
recent experiments in anesthetized, as well as in freely moving animals, demonstrate that learning-related hippocampal activities are associated with persistent changes in gabaergic interneuron firing rates and alterations in protein expression levels regulating gaba release. |
2019-08-22 |
2023-08-13 |
Not clear |
| Shauna M Stark, Craig E L Star. Excitatory/Inhibitory Imbalance in Anterior Lateral Occipital Complex Can Impair Hippocampal Mnemonic Discrimination. Neuron. vol 101. issue 3. 2019-08-15. PMID:30731057. |
(2019) explore the influence of the release of cortical inhibition on neural mnemonic representations in the hippocampus and subsequent memory performance by evaluating neural activity via functional mri, both before and after the application of tdcs aimed at increasing gaba in the anterior lateral occipital cortex. |
2019-08-15 |
2023-08-13 |
Not clear |
| Jawad Fares, Zeina Bou Diab, Sanaa Nabha, Youssef Fare. Neurogenesis in the adult hippocampus: history, regulation, and prospective roles. The International journal of neuroscience. vol 129. issue 6. 2019-08-12. PMID:30433866. |
abbreviations ahn adult hippocampal neurogenesis akt protein kinase b bmp bone morphogenic protein brdu bromodeoxyuridine cns central nervous system dg dentate gyrus disc1 disrupted-in-schizophrenia 1 fgf-2 fibroblast growth factor 2 gaba gamma-aminobutyric acid mbd1 methyl-cpg-binding domain protein 1 mecp2 methyl-cpg-binding protein 2 mtor mammalian target of rapamycin nscs neural stem cells ob olfactory bulb; p21: cyclin-dependent kinase inhibitor 1 rbpj recombination signal binding protein for immunoglobulin kappa j region rms rostral migratory stream sgz subgranular zone shh sonic hedgehog sox2 sry (sex determining region y)-box 2 svz subventricular zone wnt3 wingless-type mouse mammary tumor virus. |
2019-08-12 |
2023-08-13 |
mouse |
| Xiong-Jun Mou, Hao Ming, Le-Si Xu, Ying-Ying Yue, Yu Chen, Xin Chen, Song-Lin Li. [Active substance fractions and effects of Shugan Hewei Tang on hippocampal meurotransmitters in rat model of chronic stress-induced depression]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 44. issue 3. 2019-08-08. PMID:30989918. |
after modeling for 3 weeks and administration for 1 week, the effective substance fractions were selected according to the body mass and behavioral performance of sd rats in each group; several neurotransmitters in hippocampus of rats were determined by lc-ms/ms method, including norepinephrine(ne), serotonin(5-ht), 5-indoleacetic acid(5-hiaa), r-aminobutyric acid(gaba), and glutamic acid(glu). |
2019-08-08 |
2023-08-13 |
rat |
| Xiong-Jun Mou, Hao Ming, Le-Si Xu, Ying-Ying Yue, Yu Chen, Xin Chen, Song-Lin Li. [Active substance fractions and effects of Shugan Hewei Tang on hippocampal meurotransmitters in rat model of chronic stress-induced depression]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 44. issue 3. 2019-08-08. PMID:30989918. |
the levels of ne, 5-ht and gaba in the hippocampus of the model group were significantly lower than those in the blank group(p<0.01), and the levels of 5-hiaa and glu were significantly increased(p<0.01). |
2019-08-08 |
2023-08-13 |
rat |
| Sawsan Aboul-Fotouh, Mohamed Habib, Tarek Asaad, Samar K Kassim, Mohamed H Ghane. Behavioral effects of toll-like receptor-4 antagonist 'eritoran' in an experimental model of depression: role of prefrontal and hippocampal neurogenesis and γ-aminobutyric acid/glutamate balance. Behavioural pharmacology. vol 29. issue 5. 2019-07-31. PMID:29561292. |
we investigated the effect of long-term administration of eri in three different doses on behavioral changes, hippocampal and prefrontal cortex (pfc) neurogenesis, and γ-aminobutyric acid (gaba)/glutamate balance in male wistar rats exposed to chronic restraint stress (crs). |
2019-07-31 |
2023-08-13 |
rat |
| Sawsan Aboul-Fotouh, Mohamed Habib, Tarek Asaad, Samar K Kassim, Mohamed H Ghane. Behavioral effects of toll-like receptor-4 antagonist 'eritoran' in an experimental model of depression: role of prefrontal and hippocampal neurogenesis and γ-aminobutyric acid/glutamate balance. Behavioural pharmacology. vol 29. issue 5. 2019-07-31. PMID:29561292. |
long-term administration of eri ameliorated crs-induced depressive-like symptoms and hypothalamic-pituitary-adrenal axis hyperactivity alongside reducing levels of hippocampal and pfc inflammatory cytokines, restoring gaba and glutamate balance, and enhancing pfc and hippocampal neurogenesis, by increasing bdnf gene and protein expression in a dose-dependent manner. |
2019-07-31 |
2023-08-13 |
rat |
| Gongbei Zhu, Xiaofei Sun, Yun Yang, Yao Du, Yuhan Lin, Jianming Xiang, Ningna Zho. Reduction of BDNF results in GABAergic neuroplasticity dysfunction and contributes to late-life anxiety disorder. Behavioral neuroscience. vol 133. issue 2. 2019-07-22. PMID:30714802. |
compared to young mice, bdnf messenger rna (mrna) and protein levels and those core neuroplasticity factors (neurotransmitter γ-aminobutyric acid [gaba] level, gabaa-r α2 and α5 subunits expression and gaba+ neurons) in hippocampus markedly decreased with anxiety-like behavior in aged mice. |
2019-07-22 |
2023-08-13 |
mouse |
| M Van Zandt, E Weiss, A Almyasheva, S Lipior, S Maisel, J R Naegel. Adeno-associated viral overexpression of neuroligin 2 in the mouse hippocampus enhances GABAergic synapses and impairs hippocampal-dependent behaviors. Behavioural brain research. vol 362. 2019-07-11. PMID:30605713. |
transducing hippocampal neurons with aav-nlgn2 increased neuronal expression of nlgn2 and membrane localization of gabaergic postsynaptic proteins gephyrin and gaba |
2019-07-11 |
2023-08-13 |
mouse |
| Zhibing Tan, Heath L Robinson, Dong-Min Yin, Yu Liu, Fang Liu, Hongsheng Wang, Thiri W Lin, Guanglin Xing, Lin Gan, Wen-Cheng Xiong, Lin Me. Dynamic ErbB4 Activity in Hippocampal-Prefrontal Synchrony and Top-Down Attention in Rodents. Neuron. vol 98. issue 2. 2019-07-10. PMID:29628188. |
these observations identify a role of erbb4-dependent gaba activity in the hippocampus in synchronizing the hippocampal-prefrontal pathway and demonstrate that acute, dynamic erbb4 signaling is required to command top-down attention. |
2019-07-10 |
2023-08-13 |
mouse |
| Saiqa Tabassum, Saara Ahmad, Syeda Madiha, Saima Khaliq, Sidrah Shahzad, Zehra Batool, Saida Haide. Impact of oral supplementation of Glutamate and GABA on memory performance and neurochemical profile in hippocampus of rats. Pakistan journal of pharmaceutical sciences. vol 30. issue 3(Suppl.). 2019-07-09. PMID:28655701. |
impact of oral supplementation of glutamate and gaba on memory performance and neurochemical profile in hippocampus of rats. |
2019-07-09 |
2023-08-13 |
rat |
| Saiqa Tabassum, Saara Ahmad, Syeda Madiha, Saima Khaliq, Sidrah Shahzad, Zehra Batool, Saida Haide. Impact of oral supplementation of Glutamate and GABA on memory performance and neurochemical profile in hippocampus of rats. Pakistan journal of pharmaceutical sciences. vol 30. issue 3(Suppl.). 2019-07-09. PMID:28655701. |
levels of glu, gaba and acetylcholine (ach) were estimated in rat hippocampus. |
2019-07-09 |
2023-08-13 |
rat |
| Saiqa Tabassum, Saara Ahmad, Syeda Madiha, Saima Khaliq, Sidrah Shahzad, Zehra Batool, Saida Haide. Impact of oral supplementation of Glutamate and GABA on memory performance and neurochemical profile in hippocampus of rats. Pakistan journal of pharmaceutical sciences. vol 30. issue 3(Suppl.). 2019-07-09. PMID:28655701. |
results showed that chronic oral administration of glu and gaba tablets has a significant impact on brain function and can alter glu and gaba content in rat hippocampus. |
2019-07-09 |
2023-08-13 |
rat |
| José R Donoso, Dietmar Schmitz, Nikolaus Maier, Richard Kempte. Hippocampal Ripple Oscillations and Inhibition-First Network Models: Frequency Dynamics and Response to GABA Modulators. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 38. issue 12. 2019-07-05. PMID:29453207. |
hippocampal ripple oscillations and inhibition-first network models: frequency dynamics and response to gaba modulators. |
2019-07-05 |
2023-08-13 |
Not clear |
| Bin Qiu, Yuxue Xu, Jun Wang, Ming Liu, Longyu Dou, Ran Deng, Chao Wang, Kent E Williams, Robert B Stewart, Zhongwen Xie, Wei Ren, Zhenwen Zhao, Weinian Shou, Tiebing Liang, Weidong Yon. Loss of FKBP5 Affects Neuron Synaptic Plasticity: An Electrophysiology Insight. Neuroscience. vol 402. 2019-06-21. PMID:30685540. |
the expression of the inhibitory neurotransmitter gaba was found to be enhanced in fkbp5 ko hippocampus. |
2019-06-21 |
2023-08-13 |
mouse |