| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Rong-Xia Liu, You-Yan Xian, Sha Liu, Fei Yu, Hong-Jie Mu, Kao-Xiang Sun, Wan-Hui Li. Development, validation and comparison of surrogate matrix and surrogate analyte approaches with UHPLC-MS/MS to simultaneously quantify dopamine, serotonin and γ-aminobutyric acid in four rat brain regions. Biomedical chromatography : BMC. 2019-11-20. PMID:29727024. |
the concentrations of da and gaba were highest in striatum and hypothalamus, respectively, and the levels of 5-ht were paralleled in striatum and hippocampus almost 2-fold higher than other regions. |
2019-11-20 |
2023-08-13 |
rat |
| Katsuya Sakimura, Tatsuya Maekawa, Kazuo Sasagawa, Yukihito Ishii, Shin-Ichi Kume, Takeshi Oht. Depression-related behavioural and neuroendocrine changes in the Spontaneously Diabetic Torii (SDT) fatty rat, an animal model of type 2 diabetes mellitus. Clinical and experimental pharmacology & physiology. 2019-11-20. PMID:29757463. |
in addition, serotonin (5-hydroxytryptamine; 5-ht), noradrenaline, glutamate and γ-aminobutyric acid (gaba) concentrations in the frontal cortex, hippocampus and brain stem were measured. |
2019-11-20 |
2023-08-13 |
rat |
| Katsuya Sakimura, Tatsuya Maekawa, Kazuo Sasagawa, Yukihito Ishii, Shin-Ichi Kume, Takeshi Oht. Depression-related behavioural and neuroendocrine changes in the Spontaneously Diabetic Torii (SDT) fatty rat, an animal model of type 2 diabetes mellitus. Clinical and experimental pharmacology & physiology. 2019-11-20. PMID:29757463. |
furthermore, there were significant changes in 5-ht concentrations in the prefrontal cortex, and in gaba and glutamate concentrations in the hippocampus in sdt fatty compared with controls. |
2019-11-20 |
2023-08-13 |
rat |
| Alireza Mousavi Majd, Forough Ebrahim Tabar, Arghavan Afghani, Sahand Ashrafpour, Samaneh Dehghan, Mohammad Gol, Manouchehr Ashrafpour, Fereshteh Pourabdolhossei. Corrigendum to "Inhibition of GABA a receptor improved special memory impairment in the local model of demyelination in rat hippocampus" [Behav. Brain Res. 336 (2018) 111-121]. Behavioural brain research. vol 361. 2019-11-20. PMID:30639049. |
corrigendum to "inhibition of gaba a receptor improved special memory impairment in the local model of demyelination in rat hippocampus" [behav. |
2019-11-20 |
2023-08-13 |
rat |
| Yafei Shangguan, Xin Xu, Baigalimaa Ganbat, Yun Li, Wei Wang, Yong Yang, Xi Lu, Chao Du, Xin Tian, Xuefeng Wan. CNTNAP4 Impacts Epilepsy Through GABAA Receptors Regulation: Evidence From Temporal Lobe Epilepsy Patients and Mouse Models. Cerebral cortex (New York, N.Y. : 1991). vol 28. issue 10. 2019-11-06. PMID:28968899. |
down-regulation or overexpression of cntnap4 in the hippocampus influenced the expression of gamma-aminobutyric acid a receptor β2/3 (gabaarβ2/3) membrane protein, without affecting total gabaarβ2/3 protein concentration in epileptic mice. |
2019-11-06 |
2023-08-13 |
mouse |
| Yafei Shangguan, Xin Xu, Baigalimaa Ganbat, Yun Li, Wei Wang, Yong Yang, Xi Lu, Chao Du, Xin Tian, Xuefeng Wan. CNTNAP4 Impacts Epilepsy Through GABAA Receptors Regulation: Evidence From Temporal Lobe Epilepsy Patients and Mouse Models. Cerebral cortex (New York, N.Y. : 1991). vol 28. issue 10. 2019-11-06. PMID:28968899. |
protein interactions between cntnap4, gabaarβ2/3 and gamma-aminobutyric acid receptor-associated protein (gabarap) were observed in the hippocampus of epileptic mice. |
2019-11-06 |
2023-08-13 |
mouse |
| Kaya Xu, Zhaoyang Liu, Likun Wang, Guofeng Wu, Tao Li. Influence of hippocampal low-frequency stimulation on GABA Brain research. vol 1698. 2019-11-04. PMID:30118718. |
influence of hippocampal low-frequency stimulation on gaba this study investigated the therapeutic effect of hippocampal low-frequency stimulation (hip-lfs) and its influence on the type a γ-aminobutyric acid receptor α1 subunit (gaba |
2019-11-04 |
2023-08-13 |
Not clear |
| Hebatalla I Ahmed, Somaia A Abdel-Sattar, Heba S Zak. Vinpocetine halts ketamine-induced schizophrenia-like deficits in rats: impact on BDNF and GSK-3β/β-catenin pathway. Naunyn-Schmiedeberg's archives of pharmacology. vol 391. issue 12. 2019-10-31. PMID:30083945. |
in rats' hippocampus, ketamine induced a drastic increase in tissue levels of dopamine, lipid peroxidation, and pro-inflammatory cytokines along with a significant decrease in glutamate, gaba, sod, and total anti-oxidant capacity. |
2019-10-31 |
2023-08-13 |
rat |
| András Szőnyi, Katalin E Sos, Rita Nyilas, Dániel Schlingloff, Andor Domonkos, Virág T Takács, Balázs Pósfai, Panna Hegedüs, James B Priestley, Andrew L Gundlach, Attila I Gulyás, Viktor Varga, Attila Losonczy, Tamás F Freund, Gábor Nyir. Brainstem nucleus incertus controls contextual memory formation. Science (New York, N.Y.). vol 364. issue 6442. 2019-10-31. PMID:31123108. |
here, we found that γ-aminobutyric acid (gaba)-releasing neurons of the mouse nucleus incertus (ni) selectively inhibit somatostatin-positive interneurons in the hippocampus, both monosynaptically and indirectly through the inhibition of their subcortical excitatory inputs. |
2019-10-31 |
2023-08-13 |
mouse |
| Manimaran Ramani, Ranjit Kumar, Brian Halloran, Charitharth Vivek Lal, Namasivayam Ambalavanan, Lori L McMaho. Supraphysiological Levels of Oxygen Exposure During the Neonatal Period Impairs Signaling Pathways Required for Learning and Memory. Scientific reports. vol 8. issue 1. 2019-10-25. PMID:29967535. |
hyperoxia decreased hippocampal mglu7, trkb, akt, erk2, mtorc1, rps6, and eif4e and increased α3, α5, and ɤ2 subunits of gaba |
2019-10-25 |
2023-08-13 |
mouse |
| Jada H Vaden, Tina Tian, Samantha Golf, John W McLean, Julie A Wilson, Scott M Wilso. Chronic over-expression of ubiquitin impairs learning, reduces synaptic plasticity, and enhances GRIA receptor turnover in mice. Journal of neurochemistry. vol 148. issue 3. 2019-10-25. PMID:30451289. |
while we did not detect global changes in levels of ubiquitin conjugates in the hippocampus, we found that increasing ubiquitin levels reduced ampa (gria1-4) receptor expression without affecting the levels of nmda (grin) or gaba |
2019-10-25 |
2023-08-13 |
mouse |
| Erik H Middlebrooks, Sanjeet S Grewal, Matthew Stead, Brian N Lundstrom, Gregory A Worrell, Jamie J Van Gompe. Differences in functional connectivity profiles as a predictor of response to anterior thalamic nucleus deep brain stimulation for epilepsy: a hypothesis for the mechanism of action and a potential biomarker for outcomes. Neurosurgical focus. vol 45. issue 2. 2019-10-22. PMID:30064322. |
additionally, an inhibitory effect on the hippocampus mediated through increased hippocampal γ-aminobutyric acid (gaba) concentration may contribute to seizure suppression. |
2019-10-22 |
2023-08-13 |
Not clear |
| Lily Q Cao, Michael C Montana, Allison L Germann, Daniel J Shin, Sampurna Chakrabarti, Steven Mennerick, Carla M Yuede, David F Wozniak, Alex S Evers, Gustav Ak. Enhanced GABAergic actions resulting from the coapplication of the steroid 3α-hydroxy-5α-pregnane-11,20-dione (alfaxalone) with propofol or diazepam. Scientific reports. vol 8. issue 1. 2019-10-11. PMID:29985445. |
functional effects of the individual drugs and drug combinations were tested by measuring the decay times of spontaneous inhibitory postsynaptic currents in rat hippocampal neurons, and peak current responses from heterologously expressed concatemeric α1β2γ2l gaba |
2019-10-11 |
2023-08-13 |
mouse |
| Manar A Nader, Hayam Ateyya, Mohamed El-Shafey, Nagla A El-Sherbeen. Sitagliptin enhances the neuroprotective effect of pregabalin against pentylenetetrazole-induced acute epileptogenesis in mice: Implication of oxidative, inflammatory, apoptotic and autophagy pathways. Neurochemistry international. vol 115. 2019-09-17. PMID:29032011. |
neuronal damage was also assessed by performing tissue staining by hematoxylin and eosin, estimating hippocampus level of glutamate, gamma-aminobutyric acid (gaba), glial fibrillary acidic protein (gfap) and brain-derived neurotrophic factor (bdnf). |
2019-09-17 |
2023-08-13 |
mouse |
| Edit Szodorai, Konstantina Bampali, Roman A Romanov, Siegfried Kasper, Tomas Hökfelt, Margot Ernst, Gert Lubec, Tibor Harkan. Diversity matters: combinatorial information coding by GABA Cellular signalling. vol 50. 2019-09-17. PMID:30006122. |
diversity matters: combinatorial information coding by gaba in the hippocampus, gaba inhibition tunes network oscillations and shapes synchronous activity during spatial learning and memory coding. |
2019-09-17 |
2023-08-13 |
Not clear |
| Julia V Bukanova, Elena I Solntseva, Sergey N Kolbaev, Eva Kudov. Modulation of GABA and glycine receptors in rat pyramidal hippocampal neurones by 3α5β-pregnanolone derivatives. Neurochemistry international. vol 118. 2019-09-16. PMID:29886074. |
modulation of gaba and glycine receptors in rat pyramidal hippocampal neurones by 3α5β-pregnanolone derivatives. |
2019-09-16 |
2023-08-13 |
rat |
| J J Donegan, A M Boley, J Yamaguchi, G M Toney, D J Lodg. Modulation of extrasynaptic GABA Nature communications. vol 10. issue 1. 2019-09-03. PMID:31249307. |
modulation of extrasynaptic gaba hippocampal hyperactivity is correlated with psychosis in schizophrenia patients and likely attributable to deficits in gabaergic signaling. |
2019-09-03 |
2023-08-13 |
Not clear |
| Sueun Lee, Sohi Kang, Mary Jasmin Ang, Juhwan Kim, Jong Choon Kim, Sung-Ho Kim, Tae-Il Jeon, Chaeyong Jung, Seung-Soon Im, Changjong Moo. Deficiency of sterol regulatory element-binding protein-1c induces schizophrenia-like behavior in mice. Genes, brain, and behavior. vol 18. issue 4. 2019-08-27. PMID:30430717. |
the mrna levels of several γ-aminobutyric acid (gaba)-receptor subtypes and/or glutamic acid decarboxylase 65/67 decreased in the hippocampus and medial prefrontal cortex of srebp-1c ko mice. |
2019-08-27 |
2023-08-13 |
mouse |
| Fei Gao, Xuntao Yin, Richard A E Edden, Alan C Evans, Junhai Xu, Guanmei Cao, Honghao Li, Muwei Li, Bin Zhao, Jian Wang, Guangbin Wan. Altered hippocampal GABA and glutamate levels and uncoupling from functional connectivity in multiple sclerosis. Hippocampus. vol 28. issue 11. 2019-08-26. PMID:30069963. |
altered hippocampal gaba and glutamate levels and uncoupling from functional connectivity in multiple sclerosis. |
2019-08-26 |
2023-08-13 |
Not clear |
| Fei Gao, Xuntao Yin, Richard A E Edden, Alan C Evans, Junhai Xu, Guanmei Cao, Honghao Li, Muwei Li, Bin Zhao, Jian Wang, Guangbin Wan. Altered hippocampal GABA and glutamate levels and uncoupling from functional connectivity in multiple sclerosis. Hippocampus. vol 28. issue 11. 2019-08-26. PMID:30069963. |
however, researchers have not clearly determined whether changes in hippocampal gaba and glutamate (glu) levels are associated with cognitive impairment and aberrant neural activity in patients with ms. we used magnetic resonance spectroscopy to measure gaba+ and glu levels in the left hippocampal region of 29 patients with relapsing-remitting ms and 29 healthy controls (hcs). |
2019-08-26 |
2023-08-13 |
Not clear |