| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| K Inou. ATP receptors for the protection of hippocampal functions. Japanese journal of pharmacology. vol 78. issue 4. 1999-03-25. PMID:9920196. |
atp inhibits the release of the excitatory transmitter glutamate and stimulates the release of the inhibitory transmitter gaba from hippocampal neurons. |
1999-03-25 |
2023-08-12 |
Not clear |
| E S Vizi, J P Kis. Neurochemistry and pharmacology of the major hippocampal transmitter systems: synaptic and nonsynaptic interactions. Hippocampus. vol 8. issue 6. 1999-03-22. PMID:9882017. |
therefore the aim of this review is to summarize the neurochemical and pharmacological data on the release of the major neurotransmitters found in the hippocampal region: glutamate (glu), gamma-amino butyric acid (gaba), acetylcholine (ach), noradrenaline (na) and serotonin (5-ht). |
1999-03-22 |
2023-08-12 |
Not clear |
| A Jouvenceau, P Dutar, J M Billar. Alteration of NMDA receptor-mediated synaptic responses in CA1 area of the aged rat hippocampus: contribution of GABAergic and cholinergic deficits. Hippocampus. vol 8. issue 6. 1999-03-22. PMID:9882020. |
the nmdar-mediated fepsps were then recorded (1) in young and aged rats before and after blockade of the gaba(b) receptor-mediated inhibition by the specific antagonist cgp 55845 and (2) in young rats after a selective cholinergic denervation of the hippocampus by the immunotoxin 192 igg-saporin. |
1999-03-22 |
2023-08-12 |
rat |
| B Berger, N De Grissac, C Alvare. Precocious development of parvalbumin-like immunoreactive interneurons in the hippocampal formation and entorhinal cortex of the fetal cynomolgus monkey. The Journal of comparative neurology. vol 403. issue 3. 1999-03-15. PMID:9886033. |
these data provide the first indication that a population of basket cells, a major gamma-aminobutyric acid (gaba)ergic component of the hippocampal intrinsic inhibitory circuitry, reaches its cellular targets several weeks before birth in primates in contrast to rodents. |
1999-03-15 |
2023-08-12 |
rat |
| K E Vogt, R A Nicol. Glutamate and gamma-aminobutyric acid mediate a heterosynaptic depression at mossy fiber synapses in the hippocampus. Proceedings of the National Academy of Sciences of the United States of America. vol 96. issue 3. 1999-03-05. PMID:9927703. |
glutamate and gamma-aminobutyric acid mediate a heterosynaptic depression at mossy fiber synapses in the hippocampus. |
1999-03-05 |
2023-08-12 |
Not clear |
| X Kong, R Ren, L Li. [Effects of zinc deficiency in fodder on brain development, learning and memory in rats]. Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine]. vol 31. issue 5. 1999-02-26. PMID:9812610. |
results showed that 1. brain weight, hippocampal weight, and serum and hippocampal zinc concentrations were significantly lower in zd group than those in controls; 2. proportion of induced long-term potentiation (ltp) was zero in zd group and proportion of active avoidance response decreased profoundly in zd group, significantly lower than that in normal controls whose ltp proportion was 100%; 3. concentrations of excitatory and inhibitory amino acids, glutamic acid, gamma-aminobutyric acid in cerebral cortex and hippocampus and nitrous oxide in hippocampus were significantly higher in zd group than those in normal one, and content of somatostatin in hippocampus and dna in pyramidocytes were significantly lower in zd group than those in normal one; and 4. number of synaptic vesicles in pyramidocytes of hippocampus decreased obviously in zd group. |
1999-02-26 |
2023-08-12 |
rat |
| E X Albuquerque, E F Pereira, M F Braga, H Matsubayashi, M Alkondo. Neuronal nicotinic receptors modulate synaptic function in the hippocampus and are sensitive to blockade by the convulsant strychnine and by the anti-Parkinson drug amantadine. Toxicology letters. vol 102-103. 1999-02-25. PMID:10022256. |
evidence is provided that rapid application of nicotinic agonists to ca1 interneurons in hippocampal slices can trigger responses with at least one of three components: (i) whole-cell currents due to activation of nicotinic receptors (nachrs) on the neuron under study; (ii) fast current transients representing back-propagating action potentials; and (iii) post-synaptic currents mediated by gamma-aminobutyric acid (gaba) released from presynaptic neurons by activation of preterminal nachrs. |
1999-02-25 |
2023-08-12 |
Not clear |
| E X Albuquerque, E F Pereira, M F Braga, H Matsubayashi, M Alkondo. Neuronal nicotinic receptors modulate synaptic function in the hippocampus and are sensitive to blockade by the convulsant strychnine and by the anti-Parkinson drug amantadine. Toxicology letters. vol 102-103. 1999-02-25. PMID:10022256. |
experiments carried out in cultured hippocampal neurons demonstrated that the evoked gaba release can also be reduced by activation of these receptors, and showed that the convulsant strychnine is a competitive antagonist of alpha7 nachrs and a non-competitive antagonist of alpha4beta2 nachrs, whereas the anti-parkinson drug amantadine is a non-competitive antagonist of alpha7, alpha4beta2, and alpha3beta4 nachrs. |
1999-02-25 |
2023-08-12 |
Not clear |
| F Morin, C Beaulieu, J C Lacaill. Selective loss of GABA neurons in area CA1 of the rat hippocampus after intraventricular kainate. Epilepsy research. vol 32. issue 3. 1999-02-23. PMID:9839776. |
selective loss of gaba neurons in area ca1 of the rat hippocampus after intraventricular kainate. |
1999-02-23 |
2023-08-12 |
rat |
| C Rivera, J Voipio, J A Payne, E Ruusuvuori, H Lahtinen, K Lamsa, U Pirvola, M Saarma, K Kail. The K+/Cl- co-transporter KCC2 renders GABA hyperpolarizing during neuronal maturation. Nature. vol 397. issue 6716. 1999-02-18. PMID:9930699. |
here we show that, in pyramidal neurons of the rat hippocampus, the ontogenetic change in gaba(a)-mediated responses from depolarizing to hyperpolarizing is coupled to a developmental induction of the expression of the neuronal (cl-)-extruding k+/cl- co-transporter, kcc2. |
1999-02-18 |
2023-08-12 |
rat |
| K Fuxe, A Jansson, Z Diaz-Cabiale, A Andersson, B Tinner, U B Finnman, I Misane, H Razani, F H Wang, L F Agnati, S O Ogre. Galanin modulates 5-hydroxytryptamine functions. Focus on galanin and galanin fragment/5-hydroxytryptamine1A receptor interactions in the brain. Annals of the New York Academy of Sciences. vol 863. 1999-02-16. PMID:9928178. |
moreover, following intracerebroventricular injection galanin was found to be internalized in a population of hippocampal nerve cells mainly representing gaba, somatostatin, and/or npy-immunoreactive nerve cells. |
1999-02-16 |
2023-08-12 |
rat |
| A Rakovska, M G Giovannini, L Della Corte, R Kalfin, L Bianchi, G Pepe. Neurotensin modulation of acetylcholine and GABA release from the rat hippocampus: an in vivo microdialysis study. Neurochemistry international. vol 33. issue 4. 1999-02-10. PMID:9840224. |
neurotensin modulation of acetylcholine and gaba release from the rat hippocampus: an in vivo microdialysis study. |
1999-02-10 |
2023-08-12 |
rat |
| A Rakovska, M G Giovannini, L Della Corte, R Kalfin, L Bianchi, G Pepe. Neurotensin modulation of acetylcholine and GABA release from the rat hippocampus: an in vivo microdialysis study. Neurochemistry international. vol 33. issue 4. 1999-02-10. PMID:9840224. |
the effects of neurotensin (nt) on the release of acetylcholine (ach), aspartate (asp), glutamate (glu) and gamma-aminobutyric acid (gaba) from the hippocampus of freely moving rats were studied by transversal microdialysis. |
1999-02-10 |
2023-08-12 |
rat |
| A Rakovska, M G Giovannini, L Della Corte, R Kalfin, L Bianchi, G Pepe. Neurotensin modulation of acetylcholine and GABA release from the rat hippocampus: an in vivo microdialysis study. Neurochemistry international. vol 33. issue 4. 1999-02-10. PMID:9840224. |
neurotensin (0.2 and 0.5 microm) administered locally through the microdialysis probe to the hippocampus produced a long-lasting and concentration-dependent increase in the basal extracellular levels of gaba and ach but not of glutamate and aspartate. |
1999-02-10 |
2023-08-12 |
rat |
| A Rakovska, M G Giovannini, L Della Corte, R Kalfin, L Bianchi, G Pepe. Neurotensin modulation of acetylcholine and GABA release from the rat hippocampus: an in vivo microdialysis study. Neurochemistry international. vol 33. issue 4. 1999-02-10. PMID:9840224. |
the increase in the extracellular levels of gaba and ach produced by 0.5 microm neurotensin in the hippocampus reached a maximum of about 310% for gaba and 250% for ach. |
1999-02-10 |
2023-08-12 |
rat |
| A Rakovska, M G Giovannini, L Della Corte, R Kalfin, L Bianchi, G Pepe. Neurotensin modulation of acetylcholine and GABA release from the rat hippocampus: an in vivo microdialysis study. Neurochemistry international. vol 33. issue 4. 1999-02-10. PMID:9840224. |
the potentiating effects of neurotensin on gaba and ach release in the hippocampus are probably mediated by (i) nt receptors located on gabaergic cell bodies and (ii) through gaba(a) receptors located on cholinergic nerve terminals. |
1999-02-10 |
2023-08-12 |
rat |
| E M Bernstein, M W Quic. Regulation of gamma-aminobutyric acid (GABA) transporters by extracellular GABA. The Journal of biological chemistry. vol 274. issue 2. 1999-02-05. PMID:9873028. |
to test this hypothesis, gaba uptake assays were performed on primary dissociated rat hippocampal cultures that endogenously express gaba transporters and on mammalian cells stably expressing the cloned rat brain gaba transporter gat1. |
1999-02-05 |
2023-08-12 |
rat |
| C H Hadjiivanova, V Georgie. In vitro effect of angiotensin II on GABA release in rat hippocampus. Neuropeptides. vol 32. issue 5. 1999-02-04. PMID:9845003. |
in vitro effect of angiotensin ii on gaba release in rat hippocampus. |
1999-02-04 |
2023-08-12 |
rat |
| C H Hadjiivanova, V Georgie. In vitro effect of angiotensin II on GABA release in rat hippocampus. Neuropeptides. vol 32. issue 5. 1999-02-04. PMID:9845003. |
in rat hippocampal slices [3h]gaba release evoked by 25 mm kci consisted of ca2+-dependent and ca2+-independent fractions. |
1999-02-04 |
2023-08-12 |
rat |
| T Sooksawate, M A Simmond. Increased membrane cholesterol reduces the potentiation of GABA(A) currents by neurosteroids in dissociated hippocampal neurones. Neuropharmacology. vol 37. issue 9. 1999-02-02. PMID:9833640. |
increased membrane cholesterol reduces the potentiation of gaba(a) currents by neurosteroids in dissociated hippocampal neurones. |
1999-02-02 |
2023-08-12 |
rat |