| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| T Sooksawate, M A Simmond. Increased membrane cholesterol reduces the potentiation of GABA(A) currents by neurosteroids in dissociated hippocampal neurones. Neuropharmacology. vol 37. issue 9. 1999-02-02. PMID:9833640. |
the effects of increased membrane cholesterol on the potentiation of gaba(a) currents by pregnanolone (5beta-pregnan-3alpha-ol-20-one), allopregnanolone (5alpha-pregnan-3alpha-ol-20-one), alphaxalone (5alpha-pregnan-3alpha-ol-11,20-dione) and propofol were investigated in acutely dissociated rat hippocampal neurones using the whole-cell patch clamp technique. |
1999-02-02 |
2023-08-12 |
rat |
| E Moor, P DeBoer, B H Westerin. GABA receptors and benzodiazepine binding sites modulate hippocampal acetylcholine release in vivo. European journal of pharmacology. vol 359. issue 2-3. 1999-01-21. PMID:9832381. |
gaba receptors and benzodiazepine binding sites modulate hippocampal acetylcholine release in vivo. |
1999-01-21 |
2023-08-12 |
Not clear |
| E Moor, P DeBoer, B H Westerin. GABA receptors and benzodiazepine binding sites modulate hippocampal acetylcholine release in vivo. European journal of pharmacology. vol 359. issue 2-3. 1999-01-21. PMID:9832381. |
in the present study, the regulation of acetylcholine release from the ventral hippocampus by gamma-aminobutyric acid (gaba) was investigated in vivo. |
1999-01-21 |
2023-08-12 |
Not clear |
| E Moor, P DeBoer, B H Westerin. GABA receptors and benzodiazepine binding sites modulate hippocampal acetylcholine release in vivo. European journal of pharmacology. vol 359. issue 2-3. 1999-01-21. PMID:9832381. |
gaba receptor agonists and antagonists were administered locally in the medial septum and the adjacent vertical limb of the diagonal band of broca, or in the hippocampus by retrograde dialysis. |
1999-01-21 |
2023-08-12 |
Not clear |
| E Moor, P DeBoer, B H Westerin. GABA receptors and benzodiazepine binding sites modulate hippocampal acetylcholine release in vivo. European journal of pharmacology. vol 359. issue 2-3. 1999-01-21. PMID:9832381. |
intraseptal administration of the gaba(a) receptor agonist muscimol and the gaba(b) receptor agonist baclofen, but not the agonist of the benzodiazepine binding site midazolam, decreased acetylcholine release in the hippocampus. |
1999-01-21 |
2023-08-12 |
Not clear |
| E Moor, P DeBoer, B H Westerin. GABA receptors and benzodiazepine binding sites modulate hippocampal acetylcholine release in vivo. European journal of pharmacology. vol 359. issue 2-3. 1999-01-21. PMID:9832381. |
the gaba(a) receptor antagonist bicuculline and the antagonist of the benzodiazepine binding site flumazenil, but not the gaba(b) receptor antagonist 3-n-(3,4,-dichlorobenzyl) aminopropyl-p-diethoxymethyphosphinic acid (cgp 52432) increased acetylcholine release in the hippocampus upon intraseptal administration. |
1999-01-21 |
2023-08-12 |
Not clear |
| E Moor, P DeBoer, B H Westerin. GABA receptors and benzodiazepine binding sites modulate hippocampal acetylcholine release in vivo. European journal of pharmacology. vol 359. issue 2-3. 1999-01-21. PMID:9832381. |
the same gaba receptor ligands were administered in the ventral hippocampus. |
1999-01-21 |
2023-08-12 |
Not clear |
| E Moor, P DeBoer, B H Westerin. GABA receptors and benzodiazepine binding sites modulate hippocampal acetylcholine release in vivo. European journal of pharmacology. vol 359. issue 2-3. 1999-01-21. PMID:9832381. |
thus, endogenous gaba causes tonic inhibition of acetylcholine release in the ventral hippocampus via septal gaba(a) receptors and, to a lesser extent, via gaba(b) receptors in the medial septum and hippocampus. |
1999-01-21 |
2023-08-12 |
Not clear |
| J Francis, Y Zhang, W Ho, M C Wallace, L Zhang, J H Eubank. Decreased hippocampal expression, but not functionality, of GABA(B) receptors after transient cerebral ischemia in rats. Journal of neurochemistry. vol 72. issue 1. 1999-01-21. PMID:9886058. |
decreased hippocampal expression, but not functionality, of gaba(b) receptors after transient cerebral ischemia in rats. |
1999-01-21 |
2023-08-12 |
human |
| J Francis, Y Zhang, W Ho, M C Wallace, L Zhang, J H Eubank. Decreased hippocampal expression, but not functionality, of GABA(B) receptors after transient cerebral ischemia in rats. Journal of neurochemistry. vol 72. issue 1. 1999-01-21. PMID:9886058. |
at the level of gene expression, no significant change in gaba(b) receptor expression was observed in any hippocampal subfield at either 6 or 12 h after challenge. |
1999-01-21 |
2023-08-12 |
human |
| G B Acost. Administration of cholecystokinin sulphated octapeptide (CCK-8S) induces changes on rat amino acid tissue levels and on a behavioral test for anxiety. General pharmacology. vol 31. issue 4. 1999-01-20. PMID:9792229. |
in the hippocampus, the concentration of both glutamate (27%) and taurine (29%) were reduced, whereas the levels of gaba in the striatum (29%) were increased. |
1999-01-20 |
2023-08-12 |
rat |
| N Savić, M Sciancalepor. Intracellular calcium stores modulate miniature GABA-mediated synaptic currents in neonatal rat hippocampal neurons. The European journal of neuroscience. vol 10. issue 11. 1999-01-14. PMID:9824451. |
these results indicate that in neonatal hippocampal neurons, mobilization of calcium from caffeine-ryanodine-sensitive stores facilitates gaba release. |
1999-01-14 |
2023-08-12 |
rat |
| J L Fisher, V I Pidoplichko, J A Dan. Nicotine modifies the activity of ventral tegmental area dopaminergic neurons and hippocampal GABAergic neurons. Journal of physiology, Paris. vol 92. issue 3-4. 1999-01-13. PMID:9789810. |
the initial arrival of even a low concentration of nicotine increased the firing rate of dopaminergic neurons from the ventral tegmental area (vta) and increased the spontaneous vesicular release of gaba from hippocampal neurons. |
1999-01-13 |
2023-08-12 |
Not clear |
| E X Albuquerque, E F Pereira, M F Braga, M Alkondo. Contribution of nicotinic receptors to the function of synapses in the central nervous system: the action of choline as a selective agonist of alpha 7 receptors. Journal of physiology, Paris. vol 92. issue 3-4. 1999-01-13. PMID:9789829. |
the alpha 7-nicotinic receptor (nachr)-selective agonist choline and nachr-subtype-selective antagonists led to the discovery that activation of both alpha 7 and alpha 4 beta 2 nachrs located in ca1 interneurons in slices taken from the rat hippocampus facilitates the tetrodotoxin (ttx)-sensitive release of gamma-aminobutyric acid (gaba). |
1999-01-13 |
2023-08-12 |
rat |
| E X Albuquerque, E F Pereira, M F Braga, M Alkondo. Contribution of nicotinic receptors to the function of synapses in the central nervous system: the action of choline as a selective agonist of alpha 7 receptors. Journal of physiology, Paris. vol 92. issue 3-4. 1999-01-13. PMID:9789829. |
experiments carried out in cultured hippocampal neurons not only confirmed that preterminal alpha 7 and alpha 4 beta 2 nachrs modulate the ttx-sensitive release of gaba, but also demonstrated that evoked release of gaba is reduced by rapid exposure of the neurons to acetylcholine (ach, 10 microm-1 mm) in the presence of the muscarinic receptor antagonist atropine (1 microm). |
1999-01-13 |
2023-08-12 |
rat |
| E X Albuquerque, E F Pereira, M F Braga, M Alkondo. Contribution of nicotinic receptors to the function of synapses in the central nervous system: the action of choline as a selective agonist of alpha 7 receptors. Journal of physiology, Paris. vol 92. issue 3-4. 1999-01-13. PMID:9789829. |
a complete blockade of ach-induced reduction of evoked release of gaba was achieved only when the neurons were perfused with external solution containing both mla and dh beta e, suggesting that activation of both alpha 7 and alpha 4 beta 2 nachrs modulates the evoked release of gaba from hippocampal neurons. |
1999-01-13 |
2023-08-12 |
rat |
| M Higashima, H Kinoshita, Y Koshin. Differences in the effects of zolpidem and diazepam on recurrent inhibition and long-term potentiation in rat hippocampal slices. Neuroscience letters. vol 245. issue 2. 1999-01-07. PMID:9605489. |
we used the ca1 region of rat hippocampal slices to compare the effects of non-benzodiazepine zolpidem, which binds preferentially to the omega1 sites of gamma-aminobutyric acid a (gaba(a)) receptors, and of benzodiazepine diazepam, which binds equipotently to the omega1 and omega2 sites, on the hippocampal inhibitory mechanism and on long-term potentiation (ltp), a possible cellular mechanism for memory. |
1999-01-07 |
2023-08-12 |
rat |
| S M Sequeira, C B Duarte, A P Carvalho, C M Carvalh. Nitric oxide differentially affects the exocytotic and the carrier-mediated release of [3H] gamma-aminobutyric acid in rat hippocampal synaptosomes. Brain research. Molecular brain research. vol 55. issue 2. 1999-01-05. PMID:9582450. |
nitric oxide differentially affects the exocytotic and the carrier-mediated release of [3h] gamma-aminobutyric acid in rat hippocampal synaptosomes. |
1999-01-05 |
2023-08-12 |
rat |
| S M Sequeira, C B Duarte, A P Carvalho, C M Carvalh. Nitric oxide differentially affects the exocytotic and the carrier-mediated release of [3H] gamma-aminobutyric acid in rat hippocampal synaptosomes. Brain research. Molecular brain research. vol 55. issue 2. 1999-01-05. PMID:9582450. |
we studied the effects of nitric oxide (no) on the ca2+-dependent kcl-evoked release of gamma-aminobutyric acid (gaba) by rat hippocampal synaptosomes, measured in the presence of 1-(2-(((diphenyl-methylene)amino)oxy)ethyl)-1,2,5, 6-tetrahydro-3-pyridine-carboxylic acid (nnc-711), which blocks the gaba carrier. |
1999-01-05 |
2023-08-12 |
rat |
| M D Shumate, D D Lin, J W Gibbs, K L Holloway, D A Coulte. GABA(A) receptor function in epileptic human dentate granule cells: comparison to epileptic and control rat. Epilepsy research. vol 32. issue 1-2. 1998-12-29. PMID:9761314. |
the mossy fiber release of zinc onto dgcs coupled with the enhanced zinc sensitivity of gaba(a)rs in epileptic dgcs, may lead to 'dynamic disinhibition' which could compromise inhibitory efficacy in the epileptic rat and human hippocampus. |
1998-12-29 |
2023-08-12 |
human |