Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
F Peña, R Tapi. Relationships among seizures, extracellular amino acid changes, and neurodegeneration induced by 4-aminopyridine in rat hippocampus: a microdialysis and electroencephalographic study. Journal of neurochemistry. vol 72. issue 5. 1999-05-06. PMID:10217278. |
the three highest concentrations used induced also a dose-dependent enhancement of extracellular glutamate, aspartate, and gaba levels and profound hippocampal damage. |
1999-05-06 |
2023-08-12 |
rat |
P J Harriso. The neuropathology of schizophrenia. A critical review of the data and their interpretation. Brain : a journal of neurology. vol 122 ( Pt 4). 1999-05-06. PMID:10219775. |
a case can be made for impairment of hippocampal and corticocortical excitatory pathways, but in general the relationship between neurochemical findings (which centre upon dopamine, 5-hydroxytryptamine, glutamate and gaba systems) and the neuropathology of schizophrenia is unclear. |
1999-05-06 |
2023-08-12 |
Not clear |
J L Stringer, N Lorenz. The reduction in paired-pulse inhibition in the rat hippocampus by gabapentin is independent of GABA(B) receptor receptor activation. Epilepsy research. vol 33. issue 2-3. 1999-05-04. PMID:10094428. |
the reduction in paired-pulse inhibition in the rat hippocampus by gabapentin is independent of gaba(b) receptor receptor activation. |
1999-05-04 |
2023-08-12 |
rat |
J D Zhang, K Sait. Carbamazepine facilitates effects of GABA on rat hippocampus slices. Zhongguo yao li xue bao = Acta pharmacologica Sinica. vol 18. issue 3. 1999-04-27. PMID:10072939. |
carbamazepine facilitates effects of gaba on rat hippocampus slices. |
1999-04-27 |
2023-08-12 |
rat |
J D Zhang, K Sait. Carbamazepine facilitates effects of GABA on rat hippocampus slices. Zhongguo yao li xue bao = Acta pharmacologica Sinica. vol 18. issue 3. 1999-04-27. PMID:10072939. |
to study the influence of carbamazepine (car) on gaba effect in hippocampus. |
1999-04-27 |
2023-08-12 |
rat |
G W Mathern, D Mendoza, A Lozada, J K Pretorius, Y Dehnes, N C Danbolt, N Nelson, J P Leite, L Chimelli, D E Born, A C Sakamoto, J A Assirati, I Fried, W J Peacock, G A Ojemann, P D Adelso. Hippocampal GABA and glutamate transporter immunoreactivity in patients with temporal lobe epilepsy. Neurology. vol 52. issue 3. 1999-04-23. PMID:10025773. |
hippocampal gaba and glutamate transporter immunoreactivity in patients with temporal lobe epilepsy. |
1999-04-23 |
2023-08-12 |
Not clear |
G W Mathern, D Mendoza, A Lozada, J K Pretorius, Y Dehnes, N C Danbolt, N Nelson, J P Leite, L Chimelli, D E Born, A C Sakamoto, J A Assirati, I Fried, W J Peacock, G A Ojemann, P D Adelso. Hippocampal GABA and glutamate transporter immunoreactivity in patients with temporal lobe epilepsy. Neurology. vol 52. issue 3. 1999-04-23. PMID:10025773. |
this study determined hippocampal gamma-aminobutyric acid (gaba) and glutamate transporter immunoreactivity (ir) in temporal lobe epilepsy (tle) patients. |
1999-04-23 |
2023-08-12 |
Not clear |
J H Ye, J Ren, K Krnjević, P L Liu, J J McArdl. Cocaine and lidocaine have additive inhibitory effects on the GABAA current of acutely dissociated hippocampal pyramidal neurons. Brain research. vol 821. issue 1. 1999-04-22. PMID:10064784. |
in the present study, we investigated how cocaine and lidocaine interact to depress gaba current (igaba), recorded by the whole-cell technique in freshly isolated rat hippocampal neurons. |
1999-04-22 |
2023-08-12 |
rat |
C A Ayala-Grosso, R Urbina-Pae. Septohippocampal adaptive GABAergic responses by AF64A treatment. Journal of neuroscience research. vol 55. issue 2. 1999-04-20. PMID:9972820. |
tissue gamma-aminobutyric acid (gaba) content in the hippocampal and septal brain areas was not affected by af64a, indicating a specific effect on the cholinergic septohippocampal projection. |
1999-04-20 |
2023-08-12 |
Not clear |
C A Ayala-Grosso, R Urbina-Pae. Septohippocampal adaptive GABAergic responses by AF64A treatment. Journal of neuroscience research. vol 55. issue 2. 1999-04-20. PMID:9972820. |
the rate of gaba accumulation induced by aminooxyacetic acid administration was higher in the dorsal hippocampus and medial septum of af64a-treated animals, but not in their ventral hippocampus and lateral septum, where significant changes occurred in chat activity. |
1999-04-20 |
2023-08-12 |
Not clear |
C A Ayala-Grosso, R Urbina-Pae. Septohippocampal adaptive GABAergic responses by AF64A treatment. Journal of neuroscience research. vol 55. issue 2. 1999-04-20. PMID:9972820. |
concomitantly with the changes in gaba metabolism, a significant bmax increase and kd reduction of 3h-flunitrazepam binding in the hippocampus of af64a-treated animals were associated with changes in the chat activity. |
1999-04-20 |
2023-08-12 |
Not clear |
C A Ayala-Grosso, R Urbina-Pae. Septohippocampal adaptive GABAergic responses by AF64A treatment. Journal of neuroscience research. vol 55. issue 2. 1999-04-20. PMID:9972820. |
this finding suggests an increase of gaba input on the cholinergic somas of the medial septum and an uncompensated gabaergic interneuron activity in the hippocampus. |
1999-04-20 |
2023-08-12 |
Not clear |
M D'Antuono, H Kawasaki, V Tancredi, M Avol. Contribution of GABA(A)-mediated conductances to anoxia-induced depolarization. Neuroreport. vol 9. issue 18. 1999-04-13. PMID:9926871. |
ca1 pyramids were studied intracellularly in rat hippocampal slices to establish the contribution of excitatory amino acid (eaa) and gaba(a) receptors to the depolarizations induced by brief (< 10 min) anoxic episodes. |
1999-04-13 |
2023-08-12 |
rat |
U Bonnet, D Bingman. Missing action of carbamazepine on postsynaptic GABA-responses of hippocampal CA3-neurons (slice, guinea pig). European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 8. issue 4. 1999-04-13. PMID:9928928. |
the present study reveals that cbz failed to alter membrane potential fluctuations mediated by an activation of postsynaptic gaba(a)- and gaba(b)-receptors of hippocampal ca3-neurons even at a bath concentration of 500 microm (ca. |
1999-04-13 |
2023-08-12 |
Not clear |
M Alkondon, E F Pereira, H M Eisenberg, E X Albuquerqu. Choline and selective antagonists identify two subtypes of nicotinic acetylcholine receptors that modulate GABA release from CA1 interneurons in rat hippocampal slices. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 19. issue 7. 1999-04-13. PMID:10087082. |
choline and selective antagonists identify two subtypes of nicotinic acetylcholine receptors that modulate gaba release from ca1 interneurons in rat hippocampal slices. |
1999-04-13 |
2023-08-12 |
rat |
N A Manuel, C H Davie. Pharmacological modulation of GABA(A) receptor-mediated postsynaptic potentials in the CA1 region of the rat hippocampus. British journal of pharmacology. vol 125. issue 7. 1999-04-01. PMID:9884082. |
pharmacological modulation of gaba(a) receptor-mediated postsynaptic potentials in the ca1 region of the rat hippocampus. |
1999-04-01 |
2023-08-12 |
human |
Y Kustova, J H Ha, M G Espey, Y Sei, D Morse, A S Basil. The pattern of neurotransmitter alterations in LP-BM5 infected mice is consistent with glutamatergic hyperactivation. Brain research. vol 793. issue 1-2. 1999-03-29. PMID:9630562. |
significant decreases (60-70%) in acetylcholine concentrations were observed in the striatum, cerebral cortex and hippocampus by 12 weeks after virus inoculation, while striatal gaba concentrations decreased to 50-60% at 8-12 weeks after infection. |
1999-03-29 |
2023-08-12 |
mouse |
M H Kang, I Spigelman, R W Olse. Alteration in the sensitivity of GABA(A) receptors to allosteric modulatory drugs in rat hippocampus after chronic intermittent ethanol treatment. Alcoholism, clinical and experimental research. vol 22. issue 9. 1999-03-29. PMID:9884165. |
alteration in the sensitivity of gaba(a) receptors to allosteric modulatory drugs in rat hippocampus after chronic intermittent ethanol treatment. |
1999-03-29 |
2023-08-12 |
rat |
M H Kang, I Spigelman, R W Olse. Alteration in the sensitivity of GABA(A) receptors to allosteric modulatory drugs in rat hippocampus after chronic intermittent ethanol treatment. Alcoholism, clinical and experimental research. vol 22. issue 9. 1999-03-29. PMID:9884165. |
the alteration of gaba(a) receptor (gaba(a)r) function in the hippocampus was suggested as a possible mechanism underlying the hyperexcitability observed in cie rats, because (1) gaba(a)r agonist (muscimol)-evoked 36cl- efflux was decreased; (2) paired-pulse inhibition in the ca1 area, predominantly due to gaba(a)r-mediated recurrent inhibition, was persistently decreased; and (3) gaba(a)r subunit expression was altered in the hippocampus from cie rats. |
1999-03-29 |
2023-08-12 |
rat |
M H Kang, I Spigelman, R W Olse. Alteration in the sensitivity of GABA(A) receptors to allosteric modulatory drugs in rat hippocampus after chronic intermittent ethanol treatment. Alcoholism, clinical and experimental research. vol 22. issue 9. 1999-03-29. PMID:9884165. |
to further characterize the functional alteration of gaba(a)r after cie treatment, their sensitivity to acute ethanol, a steroid anesthetic (alphaxalone), and a benzodiazepine inverse agonist (dmcm; methyl-6,7-dimethoxy-4-ethyl-beta-carboline-3-carboxylate) were studied using either synaptically evoked gaba(a)r responses or exogenously applied muscimol-evoked responses in hippocampal slices. |
1999-03-29 |
2023-08-12 |
rat |